Corin in clinical laboratory diagnostics

► Corin is a transmembrane protease that processes natriuretic peptides. ► Corin is critical for maintaining normal blood pressure and cardiac function. ► Proteolytic shedding is an important mechanism in regulating corin activity. ► Soluble corin is detected in human blood and its levels are lower in patients with heart failure. ► Soluble corin may be used as a novel biomarker for heart failure.