Analytical evaluation of the novel soluble fms-like tyrosine kinase 1 and placental growth factor assays for the diagnosis of preeclampsia

The new BRAHMS KRYPTOR sFlt-1 and PlGF immunoassay show excellent precision and reliability. The assay results and the diagnostic capacity were highly comparable to established fully automated immunoassays (Elecsys). Hence, sFlt-1/PlGF ratio generated on KRYPTOR immunoassay platform should be suitable for diagnosing preeclampsia in clinical routine laboratory.