Expression of human and mouse adenine nucleotide translocase (ANT) isoform genes in adipogenesis

- The main expressed isoforms are mANT2 in 3T3-L1 cells and hANT3 in SGBS adipocytes.
- Adipogenesis is associated with an increase of mANT2 in 3T3-L1 and hANT3 in SGBS.
- Adipogenic factors increase mANT2 in mouse and hANT2 and hANT3 in human adipocytes.
- ANT isoforms expression pattern differs between human WAT depots.
- ANT activity is essential for adipocyte differentiation.