SOD2 is a C-myc target gene that promotes the migration and invasion of tongue squamous cell carcinoma involving cancer stem-like cells

- Cancer stem-like cells play an important role in TSCC migration and invasion.
- SOD2 mediated TSCC migration and invasion involve cancer stem-like cells.
- C-myc directly targets and regulates the expression of SOD2.
- C-myc-SOD2 pathway mediates TSCC migration and invasion involving CSCs.