Early life overfeeding decreases acylated ghrelin circulating levels and upregulates GHSR1a signaling pathway in white adipose tissue of obese young mice

► Ghrelin receptor in white adipose tissue is upregulated in young obese mice overfed during lactation. ► Ghrelin signaling pathway contributes with adipose tissue gain in offspring of young obese mice overfed during lactation. ► Early life overfeeding decreased plasmatic acylated ghrelin.