کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8453570 1547942 2018 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Smoking, alcohol, and nutritional status in relation to one-year mortality in Danish stage I lung cancer patients
ترجمه فارسی عنوان
سیگار کشیدن، الکل و وضعیت تغذیه در ارتباط با مرگ یک ساله در مرحله دانمارک، بیماران مبتلا به سرطان ریه
کلمات کلیدی
مرحله اول، پیش بینی، توتون و تنباکو، سیگار کشیدن، الکل، تمرین بالینی،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی
We included 221 patients who died within one year after diagnosis (early death) and 410 matched controls who survived more than one year (survivor). The odds ratio (OR) for early death among never-smokers was 0.3 (CI 95%: 0.1-0.9). There was no significant difference between patients who died early and survivors in proportions of current smokers (49 vs. 45%), number of cumulated pack-years (45 vs. 46), daily tobacco consumption (15 vs. 14 cigarettes/day), patients who quit smoking after diagnosis (25 vs. 40%) and the prevalence of chronic obstructive pulmonary disease (COPD) (43 vs. 38%). Patients that died early received more medications for COPD (p = 0.03) and smoked more after diagnosis, 14 vs. 10 cigarettes per day (p = 0.03). The unadjusted OR for high-risk alcohol intake was 2.2 (CI 95% 1.3-3.7) in the early death group vs. the survivors. However, in a treatment-stratified analysis this was observed only for surgically treated patients (OR, 3.2; CI 95% 1.7-6.1). Low nutritional status was associated with early death, unadjusted (OR 2.3; CI 95% 1.4-3.7), while OR was 1.8 (95% CI 1.0-2.3) adjusted for high-risk alcohol intake and COPD. Treatment selection according to and interventions against these factors before and after lung cancer diagnosis may improve outcomes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Lung Cancer - Volume 124, October 2018, Pages 40-44
نویسندگان
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