کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8684904 | 1580204 | 2018 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Reappraisal of cerebellopontine angle medulloblastomas: Report of a fatal case and lessons learned
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کلمات کلیدی
CPAICPEVDGCPGCsEGLPCA - PCADesmoplastic - دسموپلاستیCerebellopontine angle - زاویه CerebellopontineExternal ventricular drainage - زهکشی بطنی خارجیHeadache - سردردPosterior cerebral artery - شریان مغزی پشتیintracranial pressure - فشار درون جمجمهایexternal granular layer - لایه گرانشی خارجیMedulloblastoma - مدولو بلاستوماGlasgow coma scale - مقیاس کما گلاسکوhemiparesis - همیپارزیس
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
مغز و اعصاب بالینی
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چکیده انگلیسی
CPA Medulloblastomas are rare in adults. We describe a case of medulloblastoma in the right CPA in a middle aged male patient who presented with short history and was preoperatively diagnosed as vestibular schwannoma. Intra-operatively it turned out to be a highly vascular and malignant lesion. Histopathology demonstrated medulloblastoma with high ki67 index. Patient was re-explored for hematoma evacuation and remained vegetative postoperatively. This is a unique case considering the older age at presentation, short duration of symptoms with atypical presentation of only 7th, 8th and lower cranial nerve involvement. MRI showed a lobulated heterogeneous extra axial right CPA mass lesion extending in the right acoustic meatus and causing mass effect and effacement of the fourth ventricle with heterogeneous enhancement post-gadolinium, suggestive of vestibular schwannoma. The aggressive behaviour of this tumor with short history has to prompt one to keep less common lesions like medulloblastomas as differential diagnosis in the CPA region. Though medulloblastomas are rare lesions in the CPA they have to be considered in the differential diagnosis based on atypical clinical behaviour, a suspicion of such diagnosis preoperatively can alter the treatment strategy, focusing on tumor embolization, safe surgical excision and adjuvant chemoradiation, aiming towards a better quality of life, in the post-operative period.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Interdisciplinary Neurosurgery - Volume 12, June 2018, Pages 20-23
Journal: Interdisciplinary Neurosurgery - Volume 12, June 2018, Pages 20-23
نویسندگان
Sachin Ranganatha (Attending Consultant), Ashis (Director), Rahat (Consultant), Irneet (Consultant),