کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8732495 | 1590488 | 2017 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Evidence for the prevention of bone loss in elderly and old early non-metastatic breast cancer patients treated with aromatase inhibitors
ترجمه فارسی عنوان
شواهد برای جلوگیری از دست دادن استخوان در سالمندان مبتلا به سرطان سینه غیر متاستاتیک سالمند مبتلا به مهارکننده های آروماتاز
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب سالمندان و علم پیری شناسی
چکیده انگلیسی
Breast cancer (BC) is the most common cancer amongst women worldwide. Bone health is emerging as an important issue for BC survivors. In this literature study, we focus on agents for preventing bone loss in early non-metastatic estrogen receptor positive BC in treatment with aromatase inhibitors (AI) and to assess the evidence for antiresorptive treatment of bone loss in early non-metastatic breast cancer. We included randomized controlled trials (RCT's) comparing: (a) bisphosphonates and control; (b) different bisphosphonates; (c) denosumab and control and (d) bisphosphonates vs. denosumab in early non-metastatic BC women in AIÂ treatment. Among antiresorptives, zoledronic acid currently has the highest evidence for prevention of AI associated bone loss in early non-metastatic BC. Data on fracture prevention among all patients, elderly and old is sparse. More randomized controlled studies are needed with the focus of bone loss and fracture prevention especially among the elderly and old early non-metastatic BC women.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Geriatric Medicine - Volume 8, Issues 5â6, NovemberâDecember 2017, Pages 408-412
Journal: European Geriatric Medicine - Volume 8, Issues 5â6, NovemberâDecember 2017, Pages 408-412
نویسندگان
V. Gunmalm, N.R. Jørgensen, B. Abrahamsen, P. Schwarz,