کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8749722 | 1593673 | 2018 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
H-NS is an activator of exopolysaccharide biosynthesis genes transcription in Vibrio parahaemolyticus
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Vibrio parahaemolyticus is capable of surviving in biofilm communities attached to biotic and abiotic surfaces. The exopolysaccharide (EPS) plays a key role in the maturing of the biofilm. The VPA1403-1412 (cpsA-J) operon is responsible for EPS production in V. parahaemolyticus. The expression of cpsA-J is controlled by ScrABC, intracellular concentration of c-di-GMP, CpsS-CpsR-CpsQ regulatory cascade, and quorum sensing. The data presented here showed that H-NS activates the EPS-dependent bacterial colony morphology and the transcription of cpsQ and cpsA-J. H-NS has negative regulatory activity on scrABC transcription, and thereby may result in enhancing the intracellular concentration of c-di-GMP. Thus, a regulatory circuit involved in regulating cpsA-J/EPS production by H-NS, ScrABC and CpsQ was identified in V. parahaemolyticus.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microbial Pathogenesis - Volume 116, March 2018, Pages 164-167
Journal: Microbial Pathogenesis - Volume 116, March 2018, Pages 164-167
نویسندگان
Linlin Zhang, Yiwei Weng, Yu Wu, Xueying Wang, Zhe Yin, Huiying Yang, Wenhui Yang, Yiquan Zhang,