کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8752005 | 1594313 | 2018 | 31 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Isolation and genetic characterization of encephalomyocarditis virus 1 from a deceased captive hamadryas baboon
ترجمه فارسی عنوان
جداسازی و شناسایی ژنتیکی ویروس آنسفالومویوکاردیت 1 از یک بابون همدریایی اسیر مرحوم
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ویروس شناسی
چکیده انگلیسی
In 2007, numerous hamadryas baboons (Papio hamadryas) died suddenly in an aviary of a primate institute in Sochi, Russia, in the absence of prior clinical signs. Necropsies were suggestive of encephalomyocarditis virus infection, but RT-PCR assays with commonly used primers were negative. Here we report the histopathological results obtained during necropsies and the isolation and genomic characterization of a divergent strain of encephalomyocarditis virus 1 (EMCV-1) from heart tissue of one of the succumbed hamadryas baboons. Phylogenetic analysis indicates that the isolated virus belongs to the newly proposed EMCV-1 lineage G, which clusters alongside lineage C (“Mengo virus”). This study is the first report describing a lineage G strain of EMCV-1 as the etiological agent of a lethal disease outbreak among captive nonhuman primates in Europe.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Virus Research - Volume 244, 15 January 2018, Pages 164-172
Journal: Virus Research - Volume 244, 15 January 2018, Pages 164-172
نویسندگان
Oleg I. Vyshemirskii, Aslan A. Agumava, Akop A. Kalaydzyan, Andrey V. Leontyuk, Jens H. Kuhn, Alexey M. Shchetinin, Tatyana V. Vishnevskaya, Aykaz A. Eremyan, Sergey V. Alkhovsky,