NACT and laparoscopic-assisted radical vaginal trachelectomy in young patients with large (2-5 cm) high risk cervical cancers: Safety and obstetrical outcome

- NACT + C1 radical LARVT: a safe fertility-sparing approach for cervical tumors >2 cm.
- Parametrium excision minimizes oncological risk, with good obstetrical outcome.
- Pathological response informs decisions about continuing fertility sparing therapy.
- CR to NACT corresponds to low relapse risk similar to tumors <2 cm treated by LARVT.
- SD, and post NACT LVSI+, patients counseled to abandon fertility sparing therapy.