کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8840961 | 1614703 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Electro-olfactogram Responses Before and After Aversive Olfactory Conditioning in Humans
ترجمه فارسی عنوان
الکتروالفکتوگرافی قبل و بعد از تهویه مطبوع در انسان ها پاسخ می دهد
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کلمات کلیدی
EOGRM-ANOVAOSNsISI - آی اس آیElectro-olfactogram - الکتروالفکتوگرافیolfactory epithelium - اپیتلیوم بویاییrepeated-measures analysis of variance - تجزیه و تحلیل واریانس تکرار می شودfMRI - تصویرسازی تشدید مغناطیسی کارکردیfunctional magnetic resonance imaging - تصویرسازی تشدید مغناطیسی کارکردیAversive conditioning - تهویه عصبیOlfactory conditioning - تهویه مطبوعOlfactory sensory neurons - عصب های حساس ریهInterstimulus interval - فاصله بین فاصله
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
چکیده انگلیسی
The aim of the present study was to investigate whether repetitive aversive odor conditioning induced changes at the level of the peripheral olfactory system in humans. A total of 51 volunteers participated. A pair of indistinguishable odor enantiomers [(+)-rose oxide and (â)-rose oxide] were used as stimuli. During the pre-conditioning, participants' ability to discriminate between the two odors was assessed using a three-alternative, forced-choice discrimination test. In addition, electro-olfactograms (EOG) from the olfactory epithelium were recorded. Participants underwent three conditioning sessions on consecutive days. The experimental group received an electrical stimulus to the forearm only following (+)-rose oxide presentation, whereas its enantiomer sibling was never paired with the aversive stimulus; the control group did not receive any electrical stimulation. During the post-conditioning session, their ability to discriminate the two enantiomers was assessed again using the discrimination test and EOG recordings were obtained similarly to the pre-conditioning session. Results showed significant differences in the peripheral electrophysiological responses between the conditioned and the unconditioned stimulus, demonstrating contextually induced changes at the level of the first neuron in the olfactory system.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 373, 1 March 2018, Pages 199-206
Journal: Neuroscience - Volume 373, 1 March 2018, Pages 199-206
نویسندگان
Annachiara Cavazzana, Sophia C. Poletti, Cagdas Guducu, Maria Larsson, Thomas Hummel,