کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9113057 | 1156203 | 2005 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Renal responses to mesotocin in Western painted turtles compared with the antidiuretic response to arginine vasotocin
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
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چکیده انگلیسی
We have examined the renal responses to the two neurohypophysial peptides mesotocin (MT) and arginine vasotocin (AVT) in Western painted turtles (Chrysemis picta). Ureteral urine was collected, after removal of the urinary bladder, to exclude modification by trans-bladder fluxes of ions and or water. Test doses of MT ranged from 5 to 500 ng kgâ1 i.v. but only the uppermost pharmacological doses of 300 and 500 ng kgâ1 were followed by even a small reduction in GFR, a renal tubular antidiuresis, and a decrease in percent relative free-water one word clearance. A much lower, physiological, dose of 5 ng kgâ1 of AVT attenuated significantly the GFR for 30 min and decreased the percent relative free-water clearance until the end of a 150 min observation period. This is the first report of the renal response to MT in a reptile. It was concluded that MT is not a diuretic hormone, as it is in amphibians and that AVT may be the naturally occurring antidiuretic hormone in the Chelonians.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: General and Comparative Endocrinology - Volume 144, Issue 2, November 2005, Pages 101-109
Journal: General and Comparative Endocrinology - Volume 144, Issue 2, November 2005, Pages 101-109
نویسندگان
David G. Butler, Fern S. Snitman,