کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
924375 1473968 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A case of expressive-vocal amusia in a right-handed patient with left hemispheric cerebral infarction
ترجمه فارسی عنوان
یک مورد amusia expressive-vocal در یک بیمار راست دست با انفارکتوس مغزی نیمکره چپ
کلمات کلیدی
amusia اکتسابی؛ خونریزی زیر عنکبوتیه؛ ضایعه نیم کره چپ؛ گفتار ناتمام؛ fMRI
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
چکیده انگلیسی


• We report a case of amusia more dominantly related to pitch production in a dextral patient.
• The infarcted areas were limited to the left hemisphere based on MRI.
• Imaging suggested different hemispheric lateralization for speech and singing.
• Results from MRI, fMRI, and musical and neurological tests are discussed.

A 53-year-old right-handed woman had an extensive lesion in the left hemisphere due to an infarction caused by vasospasm secondary to subarachnoid bleeding. She exhibited persistent expressive-vocal amusia with no symptoms of aphasia. Evaluation of the patient’s musical competence using the Montreal Battery for Evaluation of Amusia, rhythm reproduction tests, acoustic analysis of pitch upon singing familiar music, Japanese standard language tests, and other detailed clinical examinations revealed that her amusia was more dominantly related to pitch production. The intactness of her speech provided strong evidence that the right hemisphere played a major role in her linguistic processing. Data from functional magnetic resonance imaging while she was singing a familiar song, a scale, and reciting lyrics indicated that perilesional residual activation in the left hemisphere was associated with poor pitch production, while right hemispheric activation was involved in linguistic processing. The localization of infarction more anterior to the left Sylvian fissure might be related to the dominant deficits in expressive aspects of the singing of the patient. Compromised motor programming producing a single tone may have made a major contribution to her poor singing. Imperfect auditory feedback due to borderline perceptual ability or improper audio-motor associations might also have played a role.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Cognition - Volume 103, March 2016, Pages 23–29
نویسندگان
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