Keywords: Dioxin hotspot; DHEA; Androstenedione; Testosterone; 17β-Hydroxysteroid dehydrogenase; Endocrine disruption;
مقالات ISI (ترجمه نشده)
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Keywords: 4-dione; 4-androstene-3,17-dione; 17β-HSD; 17β-hydroxysteroid dehydrogenase; 3α-diol; 3α-androstanediol; 3β-diol; 5α-androstane-3β,17β-diol; 3β-HSD; 3β-hydroxysteroid dehydrogenase; AR; androgen receptor; BC; breast cancer; DHEA; dehydroepiandro
Keywords: 17β-HSD; 17β-hydroxysteroid dehydrogenase; ACh; acetylcholine; AChE; acetylcholinesterase; CA1; region 1 of hippocampus proper; CAT; catalase; ER; estrogen receptor; fEPSP; field excitatory postsynaptic potentials; GPx; glutathione peroxidase; HFS; high
Keywords: 11KT; 11-ketotestosterone; 17bhsd; 17β-hydroxysteroid dehydrogenase; 17P; 17α-hydroxyprogesterone; 17,20bP; 17,20β-dihydroxy-4-pregnen-3-one; 20b-HSD; 20β-hydroxysteroid dehydrogenase; 20βS; 17,20β,21-trihydroxy-4-pregnen-3-one; actRIIB; activin rec
Keywords: Triclosan; Exposure; Reproductive endocrine-disruption; Steroidogenesis; Hormone receptor; TCS; triclosan; EDCs; endocrine-disrupting chemicals; PCPs; personal care products; NOAEL; no observed adverse effect level; NHANES; national health and nutrition e
Keywords: ACTH; Adrenocorticotropic hormone; caSmo; Constitutively active form of Smo; CK1; Casein kinase 1; DHEA; Dehydroepiandrosterone; E2; Estradiol; GH; Growth hormone; GSK3β; Glycogen synthase kinase-3β; Hh; Hedgehog; Kif7; Kinesin family member 7; PKA; Pro
Keywords: 11β-HSD; 11β-hydroxysteroid dehydrogenase; 17β-HSD; 17β-hydroxysteroid dehydrogenase; ACAT; acyl-CoA:cholesterol acyltransferase; DTT; dithiothreitol; DMEM; Dulbecco's modified Eagle's medium; ÎR; endoplasmic reticulum; GFP; green-fluorescent protein
Keywords: ALP; alkaline phosphatase; ALT; alanine transaminase; ANOVA; one-way analysis of variance; AST; aspartate transaminase; Cyp11a1; cholesterol side-chain cleavage enzyme; DHT; dihydrotestosterone; FSH; follicle stimulating hormone; 3β-HSD; 3β-hydroxystero
Keywords: 3β-HSD; 3β-hydroxysteroid dehydrogenase; 17β-HSD; 17β-hydroxysteroid dehydrogenase; BMP4; bone morphogenic protein 4; BW; body weight; ChIP; chromatin immunoprecipitation; CYP11A1; cytochrome P450 cholesterol side-chain cleavage enzyme; CYP17A1; cytoc
Keywords: AD; Alzheimer's disease; Aβ; β amyloid peptide; ERT; estrogen replacement therapy; ESR; estrogen receptor; E1; estrone; E2; estradiol; E3; estriol; CYP; cytochrome P450; CYP11A1; cytochrome P450 cholesterol side chain cleavage enzyme; HSD-3β; 3β-hydro
Keywords: 17β-HSD; 17β-hydroxysteroid dehydrogenase; COMT; catechol-O-methyl transferase; DHEA(S); dehydroepiandrosterone (sulfate); DHETNA; O5â²-[9-(3,17β-dihydroxy-1,3,5(10)-estratrien-16β-yl)-nonanoyl]adenosine; DNC; 3,5-dinitrocatechol; E1(S); estrone (sul
Keywords: ACTH; adrenocorticotropic hormone; AR; androgen receptor; 5α-DH-DOC; 5α-dihydro-deoxycorticosterone; CRH; corticotropin-releasing hormone; DOC; deoxycorticosterone; GC; glucocorticoid; GD; gestation day; GR; glucocorticoid receptor; 3β-HSD; 3β-hydroxy
Keywords: ACTH; adrenocorticotropic hormone; cAMP/PKA; cAMP-dependent protein kinase A; CD; cluster of differentiation; CRH; corticotrophin releasing hormone; CYP11A1 or P450scc; cytochrome P450 side-chain cleavage enzyme; CYP11B1; 11β-hydroxylase type 1; CYP11B2;
The anti-estrogenicity of chronic exposure to semicarbazide in female Japanese flounders (Paralichthys olivaceus), and its potential mechanisms
Keywords: SMC; semicarbazide; HPG axis; hypothalamic-pituitary-gonadal axis; GABA; gamma-aminobutyric acid; kiss; kisspeptin; gpr54; g-protein-coupled receptor 54; E2; 17β-estradiol; T; testosterone; ERs; estrogen receptors; VTG; vitellogenin; CHG; choriogenin; Gn
Inefficient UGT-conjugation of adrenal 11β-hydroxyandrostenedione metabolites highlights C11-oxy C19 steroids as the predominant androgens in prostate cancer
Keywords: UDP; uridine diphosphate; UGT; UDP-glucuronosyltransferases; 17βHSD; 17β-hydroxysteroid dehydrogenase; AKR1C3; 17β-hydroxysteroid dehydrogenase type 5; 11βHSD2; 11β-hydroxysteroid dehydrogenase type 2; SRD5A; 5α-reductase; SRD5A1; 5α-reductase type
Effects of daily exposure to saccharin sodium and rebaudioside A on the ovarian cycle and steroidogenesis in rats
Keywords: T1R3; taste receptor type 1 subunit 3; Gα; G protein α-gustducin; T2R38; taste receptor type 2 subunit 38; GPCR; G-protein coupled receptors; PLC-β2; phospholipase C-β2; cAMP; cyclic adenosine monophosphate; FSH; follicle-stimulating hormone; LH; lute
Secretory expression, purification and functional characterization of 17β-hydroxysteroid dehydrogenase type 1 from mammalian HEK293T cells
Keywords: 17β-HydroxySteroid dehydrogenase; Transient expression; Estradiol; Estrone; Enzyme kinetic;
Substrate inhibition of 17β-HSD1 in living cells and regulation of 17β-HSD7 by 17β-HSD1 knockdown
Keywords: 17β-HSD1; 17β-hydroxysteroid dehydrogenase; BC; breast cancer; DHT; 5α-dihydrotestosterone; E1; estrone; DHEA; dehydroepiandrosterone; E2; estradiol; STS; steroid sulfatase; ER+; estrogen-receptor positive; siRNA; small inhibitory RNA; TLC; thin-layer
Insight into the mode of action and selectivity of PBRM, a covalent steroidal inhibitor of 17β-hydroxysteroid dehydrogenase type 1
Keywords: 17β-Hydroxysteroid dehydrogenase; Steroid; Covalent inhibitor; Irreversible inhibitor; Breast cancer; Endometriosis;
Seasonal changes and sexual dimorphism in gene expression of StAR protein, steroidogenic enzymes and sex hormone receptors in the frog brain
Keywords: Neurosteroidogenesis; 3β-Hydroxysteroid dehydrogenase; 17β-Hydroxysteroid dehydrogenase; 5α-Reductase; Cytochrome P450 aromatase; Sex hormone receptors;
Evaluation of the effects of α-cypermethrin on fetal rat testicular steroidogenesis
Keywords: AGD; anogenital distance; BMD; benchmark dose; BMDL; benchmark dose limit; 3βHSD; 3β -hydroxysteroid dehydrogenase; 17βHSD; 17β-hydroxysteroid dehydrogenase; cDNA; complementary DNA; DIBP; diisobutyl phthalate; GAPDH; glyceraldehyde-3-phosphate dehydr
Human dehydrogenase/reductase (SDR family) member 11 is a novel type of 17β-hydroxysteroid dehydrogenase
Keywords: DHRS11; 17β-Hydroxysteroid dehydrogenase; 3β-Hydroxysteroid dehydrogenase; Dehydroepiandrosterone; Neurosteroid; Isolithocholic acid; SDR; short-chain dehydrogenase/reductase; DHRS11; dehydrogenase/reductase (SDR family) member 11; spDHRS11; spliced iso
Alteration of sex hormone levels and steroidogenic pathway by several low molecular weight phthalates and their metabolites in male zebrafish (Danio rerio) and/or human adrenal cell (H295R) line
Keywords: ANOVA; one-way analysis of variance; 3β HSD2; 3β-hydroxysteroid dehydrogenase; 17β hsd; 17β-hydroxysteroid dehydrogenase; 18s rrna; 18s ribosomal rna; BBzP; benzylbutyl phthalate; CHO cell; Chinese hamster ovary cell; cyp11a; cholesterol side-chain cl
Environmental enrichment attenuates the age-related decline in the mRNA expression of steroidogenic enzymes and reduces the methylation state of the steroid 5α-reductase type 1 gene in the rat hippocampus
Keywords: Aging; Environmental enrichment; Hippocampus; Neurosteroidogenic enzymes; DNA methylation; 17β-HSD; 17β-hydroxysteroid dehydrogenase; 17β-HSD-3; 17β-hydroxysteroid dehydrogenase type 3; 3α-HSD; 3α-hydroxysteroid dehydrogenase; 3β-HSD; 3β-hydroxyst
Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3
Keywords: ADT; androsterone; AR; androgen receptor; Ar; aryl group; DBD; DNA binding domain; DCM; dichloromethane; DHT; dihydrotestosterone; DIPEA; N,N-diisopropylethylamine; DMF; dimethylformamide; DMSO; dimethylsulfoxide; Î4-dione; 4-androstene-3,17-dione; EtOAc
Bioactive withanolides from Withania obtusifolia
Keywords: Withania obtusifolia; Cytotoxicity; Withanolides; Withaferin A; 17β-Hydroxysteroid dehydrogenase; 5α-Reductase;
Effects of SNP variants in the 17β-HSD2 and 17β-HSD7 genes and 17β-HSD7 copy number on gene transcript and estradiol levels in breast cancer tissue
Keywords: E2; estradiol; E1; estrone; E1S; estrone sulphate; 17β-HSD; 17β-hydroxysteroid dehydrogenase; CYP19; aromatase; SNP; single nucleotide polymorphism; ER; estrogen receptor; TF; transcription factor; 17β-HSD2; 17β-HSD7; Gene expression; Single nucleotid
Endocrine disrupting effects of benzotriazole in rare minnow (Gobiocypris rarus) in a sex-dependent manner
Keywords: AR; androgen receptor; CYP11A; cytochrome P450 side-chain cleavage; CYP17; cytochrome P450 17; CYP19; cytochrome P450 19; ER; estrogen receptor; E2; 17β-estradiol; FSHβ; follicle stimulating hormone β; FSHR; follicle stimulating hormone receptor; GnRH;
Impairment of reproductive function in a male rat model of non-alcoholic fatty liver disease and beneficial effect of N-3 fatty acid supplementation
Keywords: AC; adenylyl cyclase; cAMP; cyclic adenosine monophosphate; 17β-HSD; 17β-hydroxysteroid dehydrogenase; HC; subhaploid peak; HFD; high fat diet; LH; luteinizing hormone; LHR; luteinizing hormone receptors; NAFLD; non-alcoholic fatty liver disease; ND; no
11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer?
Keywords: Adrenal 11β-hydroxyandrostenedione; 17β-Hydroxysteroid dehydrogenase; Steroid 5α-reductase; Androgen receptor; LNCaP androgen responsive cells;
Estrogen biosynthesis, phase I and phase II metabolism, and action in endometrial cancer
Keywords: Aromatase; Sulfatase/Sulfotransferase; 17β-Hydroxysteroid dehydrogenase; Cytochromes P450; Catechol-O-methyl transferase; Estrogen receptors;
Chemical synthesis, characterisation and biological evaluation of lactonic-estradiol derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 1
Keywords: 17β-Hydroxysteroid dehydrogenase; Enzyme; Inhibitor; Steroid; Synthesis;
11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione
Keywords: 11KA4; 11-ketoandrostenedione; 11KT; 11-ketotestosterone; 11OH-5α-dione; 11β-hydroxy 5α-androstanedione; 11OH-AST; 11β-hydroxyandrosterone; 11OHA4; 11β-hydroxyandrostenedione; 11OHT; 11β-hydroxytestosterone; 11βHSD; 11β-hydroxysteroid dehydrogenas
Anabolic potential of bone mineral in human periosteal fibroblasts using steroid markers of healing
Keywords: ALP; alkaline phosphatase; AR; androgen receptor; B; deproteinized bone mineral; DHT; 5α-dihydrotestosterone; F; finasteride; FBS; foetal bovine serum; GC-MS; gas chromatography/mass spectrometry; GTR; guided tissue regeneration; HA; hydroxyapatite; HPF;
Investigation on the transcription factors of porcine 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase genes
Keywords: Pig; 3β-Hydroxysteroid dehydrogenase; 17β-Hydroxysteroid dehydrogenase; Transcription factor;
Effects of CYP7B1-related steroids on androgen receptor activation in different cell lines
Keywords: 3β-Adiol; 5α-androstane-3β,17β-diol; Aene-diol; 5-androstene-3β,17β-diol; Aene-triol; 5-androstene-3β,7α,17β-triol; AR; androgen receptor; ARE; androgen response element; CYP; cytochrome P450; DHEA; dehydroepiandrosterone; DHT; dihydrotestosteron
The role of Ala231 and Trp227 in the substrate specificities of fungal 17β-hydroxysteroid dehydrogenase and trihydroxynaphthalene reductase: Steroids versus smaller substrates
Keywords: 3HNR; trihydroxynaphthalene reductase; 17β-HSDcl; 17β-hydroxysteroid dehydrogenase from fungus Cochliobolus lunatus; DBO; 4,5-dihydroxy-2H-benzopyran-2-one; DDBO; 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one; PQ; 9,10-phenanthrenequinone; TLC; thin-lay
Identification of ovarian gene expression patterns during vitellogenesis in Atlantic cod (Gadus morhua)
Keywords: MIS; maturation inducing steroid; FOM; final oocyte maturation; GVM; germinal vesicle migration; GVBD; germinal vesicle breakdown; RDA; representational difference analysis; UTR; untranslated region; QPCR; real time quantitative PCR; 20β-HSD; 20β-hydrox
Polymorphisms in androgen signaling pathway predisposing to prostate cancer
Keywords: AKR1C3; 3α-hydroxysteroid dehydrogenase; AR; androgen receptor; CNV; copy number variation; CYP; cytochrome P450; DHEA; dehydroepiandrosterone; DHT; dehydrotestosterone; HSD17B; 17β-hydroxysteroid dehydrogenase; HSD3B; hydroxy-δ-5-steroid dehydrogenase
Synthesis and preliminary evaluation of a modified estradiol-core bearing a fused γ-lactone as non-estrogenic inhibitor of 17β-hydroxysteroid dehydrogenase type 1
Keywords: 17β-Hydroxysteroid dehydrogenase; Steroid; Estradiol; Inhibitor; Enzyme; Breast cancer;
Localization and functional activity of cytochrome P450 side chain cleavage enzyme (CYP11A1) in the adult rat kidney
Keywords: CYP11A1; cytochrome P450 side chain cleavage enzyme; CYP17; cytochrome P450 17α-hydroxylase/17,20 lyase/17,20 desmolase; GAPDH; glyceraldehyde phosphate dehydrogenase; 3β-HSD; 3β-hydroxysteroid dehydrogenase; 11β-HSD; 11β-hydroxysteroid dehydrogenase
1α,25-Dihydroxyvitamin D3 exerts tissue-specific effects on estrogen and androgen metabolism
Keywords: Vitamin D; Calcitriol; Androgens; Estrogens; Breast cancer; Aromatase; 17β-HSD; 17β-hydroxysteroid dehydrogenase; ELISA; enzyme-linked immunosorbent assay; SAM; selective aromatase modulator; TBP; TATA box binding protein; VDR; vitamin D receptor;
Does exposure to testosterone significantly alter endogenous metabolism in the marine mussel Mytilus galloprovincialis?
Keywords: Testosterone; Mytilus galloprovincialis; Testosterone acyltransferase; CYP3A; Androstenedione; 5α-Reductase; 17β-Hydroxysteroid dehydrogenase; Esterification;
Genetic Polymorphisms of 17β-Hydroxysteroid Dehydrogenase 3 and the Risk of Hypospadias
Keywords: Hypospadias; Androgens; Polymorphism; 17β-Hydroxysteroid Dehydrogenase; Development of the Penis;
Analysis of 17β-hydroxysteroid dehydrogenase types 5, 7, and 12 genetic sequence variants in breast cancer cases from French Canadian Families with high risk of breast and ovarian cancer
Keywords: Breast cancer; Genetic susceptibility; 17β-Hydroxysteroid dehydrogenase; Polymorphisms; Estrogen metabolism;
Hippocampal synthesis of estrogens and androgens which are paracrine modulators of synaptic plasticity: Synaptocrinology
Keywords: neurosteroid; P450; hippocampus; estradiol; endocrine disrupter; BPA; bisphenol A; DES; diethylstilbestrol; DHEA; dehydroepiandrosterone; LTP; long-term potentiation; PBR; peripheral benzodiazepine receptor; PREG; pregnenolone; RNase; ribonuclease; StAR;
Biochemical changes in dehydrogenase, hydroxylase and tyrosinase of a permethrin-resistant strain of housefly larvae, Musca domestica L.
Keywords: Housefly; Permethrin resistance; Aflatoxin B1 dehydrogenase; 17β-Hydroxysteroid dehydrogenase; Phenylalanine-4-hydroxylase; Tyrosinase;
Modulation of estrogen action during preimplantation period and in immature estradiol-primed rat uterus by anti-implantation agent, ormeloxifene
Keywords: Ormeloxifene; 17β-Hydroxysteroid dehydrogenase; Estrogen action; Rat; Uterus; Progesterone receptor;
Mammalian lignans and genistein decrease the activities of aromatase and 17β-hydroxysteroid dehydrogenase in MCF-7 cells
Keywords: Phytoestrogens; Lignans; Isoflavones; Aromatase; 17β-Hydroxysteroid dehydrogenase; MCF-7;
Localization of 17β-hydroxysteroid dehydrogenase in Mycobacterium sp. VKM Ac-1815D mutant strain
Keywords: 17β-Hydroxysteroid dehydrogenase; Sterol-transforming mycobacteria; Spheroplast; 17β-Reduction; Cytochemical reaction; Cell fractionation;