Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; CRAC, cholesterol recognition/interaction amino acid consensus; ER, endoplasmic reticulum; GABA, γ-amino butyric acid; GPCR, G protein-coupled receptors; HDL, high-den
مقالات ISI ABCA1، ATP اتصال گیرنده کاست A1 (ترجمه نشده)
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Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ACS, acute coronary syndrome; ADCY9, adenylate cyclase 9; apo, apolipoprotein; CAD, coronary artery disease; CETP, cholesteryl ester transfer protein; CHD, coronary heart disease; CKD, chronic kidney disease; eN
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ApoA-1, apolipoprotein A-1; ApoE, apolipoprotein E; CNS, central nervous system; COX, cyclooxygenase; COX-2, cyclooxygenase-2; Cyp46a1, cholesterol 24-hydroxylase; Dhcr24, 24-dehydrocholesterol reductase; Dhcr7,
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; Abca1, ATP-binding cassette transporter a1; BA, bile acid; CA, cholic acid; Bsep, bile salt-export pump; CDCA, chenodeoxycholic acid; Cyp, cytochrome P450; DCA, deoxycholic acid; Fxr, farnesoid X receptor; GAPDH, glyceraldehyde 3-phosphate dehydrogenase;
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ACAT, acyl-CoA:cholesterol acyltransferase; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; APOE, apolipoprotein E; BBB, blood–brain barrier; CEs, cholesterol esters; CJD, Creutzfeldt–Jakob disease;
E17110 promotes reverse cholesterol transport with liver X receptor β agonist activity in vitro
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; ApoA-I, apolipoprotein A-I; GAPDH, glyceraldehyde-phosphate dehydrogenase; HDL, high-density lipoprotein; LBD, ligand-binding domain; LXR, liver X receptor; LXRE, LXR
Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathway
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG5, ATP-binding cassette sub-family G member 5; ACC, acetyl-Coenzyme A carboxylase; ACL, ATP citrate lyase; ACS, acyl-CoA synthetase; AKT, protein kinase B (PKB); ApoE, apolipoprotein E; BAT, brown adipose ti
The natural compound berberine positively affects macrophage functions involved in atherogenesis
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; Berberine; Macrophages; Cholesterol; Atherosclerosis; InflammationacLDL, acetylated LDL; ApoA-I, apolipoprotein A-I; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; BBR, berberine; BSA, bovine serum albumin; CE, est
Isomer-specific effects of conjugated linoleic acid on HDL functionality associated with reverse cholesterol transport
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; APOA1, apolipoprotein A1; aSR-BI, antibody against SR-BI; CETP, cholesterol ester transfer protein; CLA, conjugated linoleic acid; DMEM, Dulbecco's modified Eagle's me
CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G 1; AF, activation function; AR, androgen receptor; CCAR2, cell cycle and apoptosis regulator 2; COUP-TF1, chicken ovalbumin upstream promoter transcription factor 1; ER,
microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; microRNA; RNA-binding proteins (RBPs); Cholesterol metabolism; Low density lipoprotein receptor (LDLR); Posttranscriptional regulation3′-UTR, 3′-untranslated region; ABCA1, ATP-binding cassette transporter A1; ARE, AU-rich element; FFL, feedforward loop;
Increased expression of ATP-binding cassette transporter A1 (ABCA1) as a possible mechanism for the protective effect of cilostazol against hepatic steatosis
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; PDE3, phosphodiesterase 3; HDL, high-density lipoprotein; TG, triglyceride; VLDL, very low-density lipoprotein; siRNA, small interfering RNA; ABCA1, ATP-binding cassette transporter A1; OGTT, oral glucose tolerance test; H&E, hematoxylin and eosin; PPARγ,
Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; (ABC)G1, ATP-binding cassette sub-family G member 1; apoE, apolipoprotein; CDCA, chenodeoxycholic acid; DCCC, droplet-counter-current-chromatography; FXR, farnesoid-X-receptor; GAs, gymnemic acids; LXR, liver X
The ABCA1 domain responsible for interaction with HIV-1 Nef is conformational and not linear
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; HIV-1, human immunodeficiency virus type 1; Nef, negative factor; HDL, high density lipoprotein; HEK, human embryonic kidney cells; Hcf1, host cell factor 1ABCA1; HIV-1; Nef; Interaction; Yeast 2-hybrid; Co-immu
Reduction of Liver X Receptor β expression in primary rat neurons by antisense oligodeoxynucleotides decreases secreted amyloid β levels
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; Aβ, amyloid β; ADAM10, α-secretase; AD, Alzheimer's disease; APP, amyloid-beta precursor protein; As-ODN, antisense oligodeoxynucleotides; BACE1, β-secretase; CYP46, cholesterol 24-hydroxylase; LXR, Liver X Rece
Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; AD, Alzheimer's disease; atRA, all-trans retinoic acid; CYP46A1, cholesterol 24-hydroxylase; FITC, fluorescein isothiocyanate; HDL, high-density lipoprotein; LDH, lact
Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ApoB, apolipoprotein B; HMGCoAR, 3-hydroxy-3-methylglutaryl-CoA reductase; LDL-C, low-density lipoprotein-cholesterol; LDLR, low-density lipoprotein receptor; PCSK9, proprotein convertase subtilisin/kexin 9; Q3G
Organic anion-transporting polypeptide 1a4 (Oatp1a4) is important for secondary bile acid metabolism
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; Abca1, ATP-binding cassette transporter a1; BA, bile acid; CA, cholic acid; Bsep, bile salt-export pump; CDCA, chenodeoxycholic acid; Cyp, cytochrome P450; DCA, deoxycholic acid; Fxr, farnesoid X receptor; Gapdh, glyceraldehyde 3-phosphate dehydrogenase;
Overexpression of stearoyl-coenzyme A desaturase 1 in macrophages promotes reverse cholesterol transport
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; SCD1, stearoyl-coenzyme A desaturase 1; RCT, reverse cholesterol transport; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; SR-BI, scavenger receptor class B, type ISCD1; Macrophage; Reverse cholesterol transport; H
Inflammation alters HDL composition and function: Implications for HDL-raising therapies
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; ACS, acute coronary syndrome; Akt, protein kinase B; apoA-I, apoprotein A-I; apoA-II, apoprotein A-II; apoA-IV, apoprotein A-IV; apoB, apoprotein B; apoC-II, apoprotei
Laboratory investigation of dysfunctional HDL
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; apo-A1, apolipoprotein A-1; CAD, coronary artery disease; CFA, cell-free assay; CETP, cholesteryl ester transfer protein; DCFH-DA, dichlorofluorescein diacetate; eNOS, endothelial nitric oxide synthase; FERHDL,
Role of LXR in trout adipocytes: Target genes, hormonal regulation, adipocyte differentiation and relation to lipolysis
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; 22(R)-OH, 22(R)-hydroxycholesterol; ABCA1, ATP-binding cassette transporter A1; DMSO, dimethyl sulfoxide; FAS, fatty acid synthase; GH, growth hormone; LA or 18:2n-6, linoleic acid; LPL, lipoprotein lipase; LXR, liver X receptor; LXRE, LXR response elemen
Meta-analysis on association between the ATP-binding cassette transporter A1 gene (ABCA1) and Alzheimer's disease
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; AD, Alzheimer's disease; ABCA1, ATP-binding cassette transporter A1; Aβ, Amyloid beta; CI, Confidence interval; EOAD, Early onset Alzheimer's disease; LOAD, Late onset Alzheimer's disease; HWE, Hardy–Weinberg equilibrium; OR, Odds ratioAlzheimer's disease
MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; LXR, liver X receptors; miRNA, microRNA; qPCR, quantitative PCR; ABCA1, ATP-binding cassette transporter A1; ARL7, ADP-ribosylation factor-like 7; RCT, reverse cholesterol transport; 3′UTRs, 3′ untranslated regions.MicroRNA; MiR-26; LXR; Cholesterol efflu
The HDL proteome in acute coronary syndromes shifts to an inflammatory profile
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; ACS, acute coronary syndromes; C3, complement C3; C4B, complement C4B; CAD, coronary artery disease; CRP, C-reactive protein; emPAI, exponentially modified protein ind
Site-specific oxidation of apolipoprotein A-I impairs cholesterol export by ABCA1, a key cardioprotective function of HDL
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; AGE, advanced glycation end products; ALE, advanced lipoxidation end products; apoA-I, apolipoprotein A-I; BHK, baby hamster kidney; CAD, coronary artery disease; DHP-
Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ER, Endoplasmic reticulum; Exo70, Exocyst complex protein of 70 kDa; GST, Glutathione-S-transferase; NPC, Nuclear Pore Complex; NUP62, Nucleoporin p62; ORP, OSBP-related protein; OSBP, Oxysterol-binding protein;
Detection of chymase-digested C-terminally truncated apolipoprotein A-I in normal human serum
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; apoA-I, apolipoprotein A-I; apoA-II, apolipoprotein A-II; apoE, apolipoprotein E; LDL, low-density lipoprotein; HDL, high-density lipoprotein; RCT, reverse cholesterol transport; ABCA1, ATP-binding cassette transporter A1; LCAT, lecithin cholesterol acylt
ATP-Binding cassette transporter A1 is involved in hepatic α-tocopherol secretion
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; α-TTP, α-tocopherol transfer protein; ABCA1, ATP-binding cassette transporter A1; apoA-I, apolipoprotein A-I; HDL, high-density lipoprotein; LDL, low-density lipoprotein; VLDL, very low density lipoproteinα-Tocopherol; ATP-Binding cassette transporter A1
PPARγ activates ABCA1 gene transcription but reduces the level of ABCA1 protein in HepG2 cells
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; HDL, high-density lipoproteins; LXR, liver X receptor; LXRE, LXR response element; PPAR, peroxisome proliferator-activated receptorABCA1; HDL; LXR; MEK1/2; PPARγ
Panax notoginseng saponins decrease cholesterol ester via up-regulating ATP-binding cassette transporter A1 in foam cells
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; AS, atherosclerosis; PNS, Panax notoginseng saponins; ABCA1, ATP-binding cassette transporter A1; LXRα, liver X receptor αPanax notoginseng saponins; ATP-binding cassette transporter A1; Foam cell; Macrophage; Cholesterol ester
Microvesiculation and cell interactions at the brain–endothelial interface in cerebral malaria pathogenesis
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; CM, cerebral malaria; CM-R, CM-resistant; CM-S, CM-susceptible; EC, endothelial cells; HBEC, human brain endothelial cells; MP, microparticles; MRI, multimodal resonance imaging; PfEMP-1, P. falciparum erythrocy
Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; AMPK, AMP-activated protein kinase; FAS, fatty acid synthase; FFA, free fatty acid; GSK-3β, glycogen synthase kinase-3β; HFD, high-fat diet; HNE, hydroxynonenal; LXRα, liver X receptor-α; LXRE, LXRα-response ele
HIF-1beta determines ABCA1 expression under hypoxia in human macrophages
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; HIF-1alpha, hypoxia-inducible factor, alpha subunit; ARNT (HIF-1beta), aryl-hydrocarbon receptor nuclear translocator (hypoxia-inducible factor, beta subunit); ABCA1, ATP-binding cassette transporter A1; VEGF, vascular endothelial growth factor; COX-2 (PT
Niacin and fibrates in atherogenic dyslipidemia: Pharmacotherapy to reduce cardiovascular risk
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; ACCORD, Action to Control Cardiovascular Risk in Diabetes; AFCAPS/TexCAPS, Air Force/Texas Coronary Atherosclerosis Prevention Study; AFREGS, Armed Forces Regression S
Defining lipid-binding regions of human serum amyloid A using its fragment peptides
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; apoA-I, apolipoprotein A-I; CD, circular dichroism; HDL, high-density lipoprotein; PC, phosphatidylcholine; SAA, serum amyloid A; SUV, small unilamellar vesicle; TFE, trifluoroethanol; Trp, tryptophan; WMF, wave
Eicosapentaenoic acid reduces ABCA1 serine phosphorylation and impairs ABCA1-dependent cholesterol efflux through cyclic AMP/protein kinase A signaling pathway in THP-1 macrophage-derived foam cells
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; EPA, eicosapentaenoic acid; ABCA1, ATP-binding cassette transporter A1; RCT, reverse cholesterol transport; FATP, fatty acid transfer protein; ACS, acyl-CoA synthetase; AC, adenyl cyclase; PDE, phosphodiesterase; cAMP, cyclic AMP; PKA, protein kinase A; d
Increased incorporation of dietary plant sterols and cholesterol correlates with decreased expression of hepatic and intestinal Abcg5 and Abcg8 in diabetic BB rats
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; BB, BioBreeding; Abcg5, ATP-binding cassette transporter G5; Abcg8, ATP-binding cassette transporter G8; Abca1, ATP-binding cassette transporter A1; Npc1l1, Niemann–Pick C1-like 1 protein; Lxrα, liver X receptor α; Lxrβ, liver X receptor β; Srebp2, sterol
IFN-γ down-regulates ABCA1 expression by inhibiting LXRα in a JAK/STAT signaling pathway-dependent manner
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; IFN-γ, interferon gamma; ABCA1, ATP-binding cassette transporter A1; JAK, Janus kinase; STAT, signal transducer and activator of transcription; LXRs, liver X receptors; TC, total cholesterol; FC, free cholesterol; CE, cholesterol esterATP-binding cassette
Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; APN, adiponectin; APN-KO, adiponectin knockout; ApoA-I, apolipoprotein A-I; BSA, bovine serum albumin; CAD, coronary artery disease; HDL, high density lipoprotein; LDL
Effects of coumestrol on lipid and glucose metabolism as a farnesoid X receptor ligand
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; AP, alkaline phosphatase; apoB, apolipoprotein B; apoC-III, apolipoprotein C-III; BAP, bacterial alkaline phosphatase; CDCA, chenodeoxy cholic acid; CoA-BAP, coactivator-bacterial alkaline phosphatase; DMSO, dim
ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-β peptide (1–40) at the blood–brain barrier
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; Aβ, amyloid-β peptide; ABCA1, ATP-binding cassette transporter A1; AD, Alzheimer's disease; apo A–I, apolipoprotein A–I; APP, amyloid precursor protein; BBB, blood–brain barrier; BEI, brain efflux index; ECF, extracellular fluid; hAβ(1–40), human Aβ(1–40)
Lipidation of apolipoprotein A-I by ATP-binding cassette transporter (ABC) A1 generates an interaction partner for ABCG1 but not for scavenger receptor BI
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; HDL, high density lipoprotein; rHDL, reconstituted HDL; apoA-I, apolipoprotein A-I; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; SR-BI, scavenger receptor BI; LDL, low density lipoprotein; acLDL, acetylated LDL;
Cholesteryl ester transfer protein genetic polymorphisms, HDL cholesterol, and subclinical cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; CAC, coronary artery calcium; CETP, cholesteryl ester transfer protein; CVD, cardiovascular disease; HDL, high-density lipoprotein; HDL-C, HDL-cholesterol; IMT, intimal-medial thickness; MESA, Multi-Ethnic Study
The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; apoAI, apolipoprotein AI; HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-CoA; HMDMs, human monocyte-derived macrophages; HPβCD, 2-hydroxypropyl-β-cyclodextrin; LXRα, li
Adiponectin deficiency suppresses ABCA1 expression and ApoA-I synthesis in the liver
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; APN, adiponectin; apoA-I, apolipoprotein A-I; apoB-100, apolipoprotein B-100; CAD, coronary artery disease; CM, chylomicron; FC, free cholesterol; HDL, high density li
Hypolipidemic effects and mechanisms of Panax notoginseng on lipid profile in hyperlipidemic rats
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; LXRα, liver X receptor α; FXR, Farnesoid X receptor; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ABCA1, ATP-binding Cassette Transporter A1; ABCG5, ATP-binding Cassette
22-Hydroxycholesterols regulate lipid metabolism differently than T0901317 in human myotubes
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; 22-R-HC, 22-R-hydroxycholesterol; 22-S-HC, 22-S-hydroxycholesterol; ACSL1, acyl-CoA synthetase long chain family member 1; ABCA1, ATP-binding cassette transporter A1; CD36, fatty acid transporter; DAG, diacylglycerol; FAS, fatty acid synthase; FFA, free f
Overexpression of SND p102, a rat homologue of p100 coactivator, promotes the secretion of lipoprotein phospholipids in primary hepatocytes
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; aa, amino acid; ABCA1, ATP-binding cassette transporter A1; apo, apolipoprotein; Ch, cholesterol; ChE, cholesteryl ester; DAPI, 4′,6-diamidino-2-phenylindol; ECL, enhanced chemiluminescence; ER, endoplasmic reticulum; HDL, high density lipoprotein; m.o.i.
Increased cellular cholesterol efflux in glycogen storage disease type Ia mice: A potential mechanism that protects against premature atherosclerosis
Keywords: ABCA1، ATP اتصال گیرنده کاست A1; GSD-Ia, glycogen storage disease type Ia; SR-BI, scavenger receptor class B type I; ABCA1, ATP-binding cassette transporter A1; G6Pase-α, glucose-6-phosphatase-α; HDL, high density lipoprotein; LDL, low density lipoprotein; VLDL, very low density lipoprot