Keywords: ACVR1; Activin A receptor, type I; BMP; Bone morphogenetic protein; bTBI; Blast-related traumatic brain injury; CNS; Central nervous system; FOP; Fibrodysplasia ossificans progressive; HIF-1α; Hypoxia inducible factor alpha; HO; Heterotopic ossification;
مقالات ISI (ترجمه نشده)
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Keywords: FOP; POH; AHO; GNAS; Gsα; ACVR1; Trauma-induced; Neurogenic; TGF-β; Osteoblast; XLαs; NESP55; Imprint; Osseous metaplasia; Malignancies; ALK; BMP; Gli; PTHrP; Hedgehog;
Keywords: ACVR1; Activin A receptor type1; ATRX; A-thalassemia/mental retardation syndrome X-linked; BMP; Bone morphogenetic protein; BRAF; v-Raf murine sarcoma viral oncogene homolog B; CNS; Central nervous system; DAXX; Death domain-associated protein; DNMT; DNA
Keywords: ALKs; activin receptor-like (type I) kinases; BMP; bone morphogenetic protein; BMPRII; BMP type II receptor; FKBP12; FK506-binding protein 12â¯kDa; FOP; Fibrodysplasia Ossificans Progressiva; AMPK; AMP-activated protein kinase; SMKI; small molecule kinas
Keywords: Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A
Longitudinal patient-reported mobility assessment in fibrodysplasia ossificans progressiva (FOP)
Keywords: Fibrodysplasia ossificans progressiva; Heterotopic ossification; ACVR1; Joint function; Patient-reported outcomes;
Cartilage-derived retinoic acid-sensitive protein (CD-RAP): A stage-specific biomarker of heterotopic endochondral ossification (HEO) in fibrodysplasia ossificans progressiva (FOP)
Keywords: Fibrodysplasia ossificans progressiva (FOP); Heterotopic ossification; Cartilage-derived retinoic acid-sensitive protein (CD-RAP); RARγ agonists; Biomarker; ACVR1;
Acute unilateral hip pain in fibrodysplasia ossificans progressiva (FOP)
Keywords: Fibrodysplasia ossificans progressiva (FOP); Heterotopic ossification; Bone morphogenetic protein (BMP); Bone morphogenetic protein signaling; ACVR1;
Activin A amplifies dysregulated BMP signaling and induces chondro-osseous differentiation of primary connective tissue progenitor cells in patients with fibrodysplasia ossificans progressiva (FOP)
Keywords: Fibrodysplasia ossificans progressiva (FOP); Heterotopic ossification; Bone morphogenetic protein (BMP); Bone morphogenetic protein signaling; ACVR1; Activin A;
ACVR1 is essential for periodontium development and promotes alveolar bone formation
Keywords: ACVR1; BMP signaling; Cell interaction; RANKL/OPG; Osteoblast; Osteoclast;
Acute and chronic rapamycin use in patients with Fibrodysplasia Ossificans Progressiva: A report of two cases
Keywords: Fibrodysplasia Ossificans Progressiva (FOP); Heterotopic ossification; Rapamycin; ACVR1;
Variant BMP receptor mutations causing fibrodysplasia ossificans progressiva (FOP) in humans show BMP ligand-independent receptor activation in zebrafish
Keywords: FOP; BMP signaling; ACVR1; Smad1/5; Zebrafish; Dorsal-ventral embryonic patterning;
The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva
Keywords: Fibrodysplasia Ossificans Progressiva; Heterotopic Ossification; Activin A; ACVR1; Anti-Activin antibody; Progenitor cells;
Imaging assessment of fibrodysplasia ossificans progressiva: Qualitative, quantitative and questionable
Keywords: FOP; fibrodysplasia ossificans progressiva; CT; computed tomography; HO; heterotopic bone; ACVR1; activin A type I receptor; ALK2; activin-like kinase2; mSv; millisievert; AP; anterioposterior; MRI; magnetic resonance imaging; US; Ultrasonography; 99Â m T
Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases
Keywords: Fibrodysplasia ossificans progressiva (FOP); Heterotopic ossification; Imatinib; Bone morphogenetic protein (BMP) signaling; HIF1-α; ACVR1; PDGFRα; c-Kit;
Variable signaling activity by FOP ACVR1 mutations
Keywords: ACVR1; activin A receptor type 1; BMP; bone morphogenetic protein; HO; heterotopic ossification; FOP; fibrodysplasia ossificans progressiva; LBD; extracellular ligand-binding domain; GS; glycine-serine rich domain; PK; protein kinase domain; TGF-beta; tra
Drosophila models of FOP provide mechanistic insight
Keywords: Fibrodysplasia Ossificans Progressiva; ACVR1; ALK2; Sax; BMP signaling; Heterotopic ossification;
Mast cell inhibition as a therapeutic approach in fibrodysplasia ossificans progressiva (FOP)
Keywords: Mast cells; Fibrodyplasia ossificans progressiva (FOP); Heterotopic ossification; ACVR1; Cromolyn;
Stem cells and heterotopic ossification: Lessons from animal models
Keywords: Animal models; Heterotopic ossification; Stem cells; Progenitor cells; Fibrodysplasia ossificans progressiva; FOP; ACVR1; ALK2; Activin; BMP; Fibro/adipogenic progenitors; FAPs; Satellite cell; Endothelium; Skeletal muscle; Tendon; PDGFRα; TIE2; Scleraxi
Joint-specific risk of impaired function in fibrodysplasia ossificans progressiva (FOP)
Keywords: Fibrodysplasia ossificans progressiva; Heterotopic ossification; Bone morphogenetic protein signaling; ACVR1; Joint survival; Risk;
ECSIT links TLR and BMP signaling in FOP connective tissue progenitor cells
Keywords: Fibrodysplasia ossificans progressiva (FOP); Heterotopic ossification; Bone morphogenetic protein (BMP); Bone morphogenetic protein signaling; ACVR1; Activin A; Toll-like receptor (TLR); ECSIT; Innate immune system;
BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development
Keywords: BMP Smad signaling; Bmpr1a; Bmpr1b; Acvr1; Craniosynostosis;
The congenital great toe malformation of fibrodysplasia ossificans progressiva? - A close call
Keywords: Fibrodysplasia ossificans progressiva; Heterotopic ossification; Brachydactyly; Bone morphogenetic protein (BMP) signaling; ACVR1; BMP receptor IB;
A cumulative analogue joint involvement scale (CAJIS) for fibrodysplasia ossificans progressiva (FOP)
Keywords: Fibrodysplasia ossificans progressiva; Heterotopic ossification; Bone morphogenetic protein signaling; ACVR1; Activities of daily living; Ambulation;
A novel ACVR1 mutation detected by whole exome sequencing in a family with an unusual skeletal dysplasia
Keywords: Whole exome sequencing; ACVR1; Skeletal dysplasia; Fibrodysplasia ossificans progressiva; FOP variant
ACVR1-Fc suppresses BMP signaling and chondro-osseous differentiation in an in vitro model of Fibrodysplasia ossificans progressiva
Keywords: Fibrodysplasia ossificans progressiva; Heterotopic ossification; BMP signaling; ACVR1; ALK2;
Micronome revealed miR-19a/b as key regulator of SOCS3 during cancer related inflammation of oral squamous cell carcinoma
Keywords: OSCC; Oral Squamous Cell Carcinoma; miRNA; MicroRNA; NGS; Next Generation Sequencing; STRING; Search Tool for Retrieval of Interacting Genes/Proteins; ACTREC; Advanced Centre for Treatment Research and Education in Cancer; HNOCDB; Head Neck Oral Cancer Da
Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders
Keywords: ACVR1; ALK2; Fibrodysplasia Ossificans Progressiva; Diffuse Intrinsic Pontine Gliomas; Orphan diseases; BMP signaling
Original Full Length ArticleInhibition of TGFβ signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease
Keywords: FOP; fibrodysplasia ossificans progressiva; FCS; fetal calf serum; BMP; bone morphogenetic protein; TGFβ; transforming growth factor β; Runx2; runt-related transcription factor 2; Alp; alkaline phosphatase; OC; osteocalcin; ACVR1; activin receptor IA; A
Granting immunity to FOP and catching heterotopic ossification in the Act
Keywords: Fibrodysplasia ossificans progressiva (FOP); Heterotopic ossification; Bone morphogenetic protein (BMP); Bone morphogenetic protein signaling; Innate immune system; ACVR1; Activin A; Toll-like receptor (TLR);
BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse
Keywords: BMP; Bmpr1a; Bmpr1b; Acvr1; Alk2; Alk3; Alk6; Smad4; Sox9; Cartilage; Mesenchymal condensation; Mouse;
BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints
Keywords: Nfatc1; ALK2; Acvr1; BMP receptor; Heterotopic ossification; Fibrodysplasia ossificans progressive; FOP; Cartilage; Bone; Endochondral ossification;
The phenotype and genotype of fibrodysplasia ossificans progressiva in China: A report of 72 cases
Keywords: Fibrodysplasia ossificans progressiva; Heterotopic ossification; Bone morphogenetic protein; ACVR1; ALK2;
Fibrodysplasia ossificans progressiva in Spain: epidemiological, clinical, and genetic aspects
Keywords: Fibrodysplasia ossificans progressiva; FOP; Heterotopic ossification; ACVR1; BMP type I receptor
A novel ACVR1 mutation in the glycine/serine-rich domain found in the most benign case of a fibrodysplasia ossificans progressiva variant reported to date
Keywords: Fibrodysplasia ossificans progressiva; FOP; ACVR1; Heterotopic ossification; Mutation
Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1
Keywords: ACVR1; activin A receptor type I; ALK; activin receptor-like kinase; BMP; bone morphogenetic protein; BMPR; BMP receptor; DEXA; dual-emission X-ray absorptiometry; E; embryonic day; FOP; fibrodysplasia ossificans progressiva; HBM; high bone mass; P; postn
The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling
Keywords: Fibrodysplasia ossificans progressiva; Heterotopic ossification; Bone morphogenetic protein (BMP) receptor; BMP signaling; Metamorphosis; Metamorphogene; ACVR1; Activin-like kinase 2 (ALK2);
Insights from a rare genetic disorder of extra-skeletal bone formation, fibrodysplasia ossificans progressiva (FOP)
Keywords: ACVR1; ALK2; BMP type I receptor; Fibrodysplasia ossificans progressiva (FOP); Bone morphogenetic protein (BMP);
Fibrodysplasia ossificans progressiva
Keywords: fibrodysplasia ossificans progressiva (FOP); heterotopic ossification; bone morphogenetic protein; BMP; ACVR1; ALK2
Expression of Fgf and Tgfβ signaling related genes during embryonic endochondral ossification
Keywords: Endochondral ossification; Chondrocyte differentiation; Ihh; Pthr; Bmp2; Bmp3; Bmp4; Bmp6; Bmp7; Noggin; Follistatin; Inhβa; Activin; Tgfβ1; Tgfβ2; Tgfβ3; Bmpr1a; Bmpr1b; Bmpr2; Acvrl1; Acvr1; Acvr1b; Acvr2; Tgfβr1; Smad1; Smad3; Smad5; Fgf2; Fgf8; F