Keywords: Nonsteroidal anti-inflammatory drug; Glucuronidation; Acyl glucuronide; Protein binding; Stereoselectivity;
مقالات ISI (ترجمه نشده)
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Keywords: Acyl glucuronide; Drug development; Drug toxicity; In vitro screening; In vivo model; Immune activation; Protein adduct; Reactive metabolite; UDP-glucuronosyltransferase; ADR; adverse drug reaction; AG; acyl glucuronide; AGE; advanced glycation end prod
The practical synthesis of β-acyl glucuronides by using allyl 2,3,4-tri-(O-allyloxycarbonyl)-d-glucuronate and 1-chloro-N,N,2-trimethyl-1-propenylamine
Keywords: WOZQDFXLVFOKMX-ICOHNFKGSA-N; VWGCZKRMVWYVEJ-LSNALIEQSA-N; ZVWMFMGULWTPKG-YNAZQSIESA-N; YNONIMVEZPHEHC-WGFGEXONSA-N; Acyl glucuronide; 1-Chloro-N,N,2-trimethylpropenylamine; Allyl 2,3,4-tri-(O-allyloxycarbonyl)-d-glucuronate; Aryl carboxylic acid;
Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design
Keywords: mPGES-1; Benzoxazole; Solubility; Acyl glucuronide; Conformational analysis
The acyl glucuronide metabolite of mycophenolic acid induces tubulin polymerization in vitro
Keywords: Mycophenolic acid; Immunosuppression; Acyl glucuronide; Tubulin polymerization; Antiproliferative effect
Simultaneous determination of mycophenolic acid and its acyl and phenol glucuronide metabolites in human serum by capillary zone electrophoresis
Keywords: Capillary zone electrophoresis; Mycophenolic acid; Acyl glucuronide; Phenol glucuronide; Renal transplant patient
Proteins identified as targets of the acyl glucuronide metabolite of mycophenolic acid in kidney tissue from mycophenolate mofetil treated rats
Keywords: Acyl glucuronide; Toxico proteomics; Kidney transplant; Mycophenolic acid; Adducts
Transport of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide by human intestinal Caco-2 cells
Keywords: ACSRC; Auckland Cancer Society Research Centre; AP; apical; BL; basolateral; CYP; cytochrome P450; DMSO; dimethyl sulphoxide; DMXAA; 5,6-dimethylxanthenone-4-acetic acid; DMXAA-G; DMXAA acyl glucuronide; HBSS; Hanks' balanced salt solution; HEPES; N-[2-