Keywords: آگوملاتین; agomelatine; amorphous; micro-Raman; ATR-FTIR; X-ray powder diffractometry; bioavailability; pour water-soluble drugs;
مقالات ISI آگوملاتین (ترجمه نشده)
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Keywords: آگوملاتین; Agomelatine; Constant chronic light; Depression; Circadian rhythms; Melatonin; Corticosterone;
Keywords: آگوملاتین; Agomelatine; Inadequate response; Major depressive disorder; Switch; Vortioxetine;
Keywords: آگوملاتین; Agomelatine; Epilepsy; Depression; Interleukin-1β; Neuroglia; Wistar rat;
Keywords: آگوملاتین; Agomelatine; SVR; ANN; OPLS; Spectrofluorimetry; Nonlinear;
Keywords: آگوملاتین; Cerebral ischemia/reperfusion; Agomelatine; Apoptosis; Antioxidant; Melatonin; Nrf2;
Keywords: آگوملاتین; Agomelatine; Bcl-2; BDNF; BrdU; Caspase-3; Hippocampus;
Keywords: آگوملاتین; Agomelatine; Opioid receptor; Hot-plate test; Tail-clip test; Acetic acid-induced writhing test
Keywords: آگوملاتین; Depression; Decreased motivation; Animal model; Operant; Circadian rhythm; Agomelatine;
Keywords: آگوملاتین; Prediction; Joy; Emotion; Sadness; Treatment response; Major depressive disorder; Agomelatine;
Keywords: آگوملاتین; Agomelatine; Analogues; PC12 cells; Corticosterone; Forced swim test;
Keywords: آگوملاتین; Agomelatine; Co-crystal; DITA; Solubility; Ternary phase diagram
Keywords: آگوملاتین; Agomelatine; Glaucoma; Hypertensive condition; IOP; Melatonin; Melatonin receptor;
Keywords: آگوملاتین; Penis; Corpus cavernosum; Imipramine; Agomelatine; Moclobemide; Erectile dysfunction;
Keywords: آگوملاتین; Traxoprodil; Agomelatine; Mianserin; Tianeptine; Forced swim test
Keywords: آگوملاتین; Agomelatine; Depression; Placebo; Dose regimen; Long-termMDD, major depressive disorder
Effect of agomelatine 25-50â¯mg on functional outcomes in patients with major depressive disorder
Keywords: آگوملاتین; Agomelatine; Depression; Placebo; Functioning; Short-term; Sheehan disability scale; Pooled analysis;
Agomelatine-induced modulation of brain-derived neurotrophic factor (BDNF) in the rat hippocampus
Keywords: آگوملاتین; Agomelatine; Chronic unpredictable mild stress; Brain-derived neurotrophic factors; Depression; Fluoxetine;
12-week double-blind randomized multicenter study of efficacy and safety of agomelatine (25-50â¯mg/day) versus escitalopram (10-20â¯mg/day) in out-patients with severe generalized anxiety disorder
Keywords: آگوملاتین; Agomelatine; Escitalopram; Generalized anxiety disorder;
A novel concept of overcoming the skin barrier using augmented liquid nanocrystals: Box-Behnken optimization, ex vivo and in vivo evaluation
Keywords: آگوملاتین; Agomelatine; Box-Behnken; Liquid nanocrystals; Optimization; Transdermal;
CeO2/g-C3N4 nanocomposite: A perspective for electrochemical sensing of anti-depressant drug
Keywords: آگوملاتین; CeO2/g-C3N4 nanocomposite; Agomelatine; Electrochemical sensor; Voltammetry;
Ultrasonically tailored, chemically engineered and “QbD” enabled fabrication of agomelatine nanoemulsion; optimization, characterization, ex-vivo permeation and stability study
Keywords: آگوملاتین; Agomelatine; Nanoemulsion; Pseudo-ternary phase diagram; Ultrasonication; Central composite design; Atomic force microscopy;
Agomelatine's effect on circadian locomotor rhythm alteration and depressive-like behavior in 6-OHDA lesioned rats
Keywords: آگوملاتین; Parkinson's disease; Circadian rhythm; Locomotor activity; 6-OHDA; Agomelatine; Depression;
Effects of agomelatine on pentylenetetrazole-induced kindling, kindling-associated oxidative stress, and behavioral despair in mice and modulation of its actions by luzindole and 1-(m-chlorophenyl) piperazine
Keywords: آگوملاتین; Agomelatine; PTZ-kindling; Forced swim test; Spatial memory; Oxidative stress; Liver enzymes;
Agomelatine, a MT1/MT2 melatonergic receptor agonist with serotonin 5-HT2C receptor antagonistic properties, suppresses Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages
Keywords: آگوملاتین; Agomelatine; Prevotella intermedia; Lipopolysaccharide; Proinflammatory mediators;
Original articleAnhedonia predicts poor psychosocial functioning: Results from a large cohort of patients treated for major depressive disorder by general practitioners
Keywords: آگوملاتین; Unipolar depression; Anhedonia; Psychosocial functioning; Antidepressant; Agomelatine; Quality of life;
Efficacy and safety of agomelatine (10 or 25 mg/day) in non-depressed out-patients with generalized anxiety disorder: A 12-week, double-blind, placebo-controlled study
Keywords: آگوملاتین; Agomelatine; Generalized anxiety disorder; Placebo;
Synthesis and biological evaluation of new naphtho- and quinolinocyclopentane derivatives as potent melatoninergic (MT1/MT2) and serotoninergic (5-HT2C) dual ligands
Keywords: آگوملاتین; Melatonin; Serotonin; Agomelatine; Levogyre; Dextrogyre;
Early effect on general interest, and short-term antidepressant efficacy and safety of agomelatine (25-50 mg/day) and escitalopram (10-20 mg/day) in outpatients with Major Depressive Disorder. A 12-week randomised double-blind comparative study
Keywords: آگوملاتین; MDD; Major Depressive Disorder; 5-HT; Serotonin; Agomelatine; Antidepressant; Escitalopram; General interest; Outpatients;
Studies on the reproductive effects of chronic treatment with agomelatine in the rat
Keywords: آگوملاتین; Agomelatine; Antidepressant; Sexual behavior
Augmentation of antidepressant effects of venlafaxine by agomelatine in mice are independent of kynurenine pathway
Keywords: آگوملاتین; Agomelatine; Venlafaxine; Chronic forced swim test; Tail suspension test; Kynurenine; Tryptophan
Implementation of a reference-scaled average bioequivalence approach for highly variable generic drug products of agomelatine in Chinese subjects
Keywords: آگوملاتین; Reference-scaled average bioequivalence; Agomelatine; 3-Hydroxy-agomelatine; 7-Desmethyl-agomelatine; Chinese subjects; High variability; Generic drug
Heart rate variability in major depressive disorder and after antidepressant treatment with agomelatine and paroxetine: Findings from the Taiwan Study of Depression and Anxiety (TAISDA)
Keywords: آگوملاتین; ANOVA; Analysis of variance; BMI; Body mass index; BDI; Beck Depression Inventory; BAI; Beck Anxiety Inventory; CVD; Cardiovascular disease; DBP; Diastolic blood pressure; HRV; Heart rate variability; HAM-D; Hamilton Depression Rating Scale; HAM-A; Hamilt
Agomelatine affects rat suprachiasmatic nucleus neurons via melatonin and serotonin receptors
Keywords: آگوملاتین; 5-HT, 5-hydroxytryptamine, serotonin; ACSF, artificial cerebrospinal fluid; cAMP, cyclic adenosine monophosphate; DMSO, dimethyl sulfoxide; PLC, phospholipase C; MT, melatonin; SCN, suprachiasmatic nucleusSuprachiasmatic nucleus; Melatonin; Agomelatine; 5
Development, validation and comparison of UHPSFC and UHPLC methods for the determination of agomelatine and its impurities
Keywords: آگوملاتین; Agomelatine; UHPSFC; Ultra-high performance supercritical fluid chromatography; UHPLC; Ultra-high performance liquid chromatography; Method development;
Inclusion complexes of HP-β-cyclodextrin with agomelatine: Preparation, characterization, mechanism study and in vivo evaluation
Keywords: آگوملاتین; Hydroxypropyl-β-cyclodextrin inclusion complex; Agomelatine; Inclusion mechanism; Molecular modeling studies; Absorption; Pharmacokinetics
Research reportConsequences of long-term treatment with agomelatine on depressive-like behavior and neurobiological abnormalities in pinealectomized rats
Keywords: آگوملاتین; Pinealectomy; Agomelatine; Behavior; Serotonin; HPA axis; Neuronal loss;
Development and validation a LC–MS/MS method for the simultaneous determination of agomelatine and its metabolites, 7-desmethyl-agomelatine and 3-hydroxy-agomelatine in human plasma: Application to a bioequivalence study
Keywords: آگوملاتین; LC–MS/MS; Agomelatine; 7-Desmethyl-agomelatine; 3-Hydroxy-agomelatine; Metabolite; Plasma; Bioequivalence
Synthesis and pharmacological evaluation of dual ligands for melatonin (MT1/MT2) and serotonin 5-HT2C receptor subtypes (II)
Keywords: آگوملاتین; Agomelatine; Modulation; Melatonin receptors; MT2-Selectivity; Serotonin 5-HT2C receptor
Melatonin receptor and KATP channel modulation in experimental vascular dementia
Keywords: آگوملاتین; Acetylcholinesterase; Agomelatine; Nicorandil; Donepezil; Mitochondrial enzyme complex; Myeloperoxidase;
Agomelatine restores a physiological response to stress in the aged rat
Keywords: آگوملاتین; Immobilization stress; Younger or Older rats; Slow wave sleep (SWS); Rapid eye movement sleep (REM sleep); Sleep rebound; Agomelatine;
Acute and chronic effects of agomelatine on intravenous penthylenetetrazol-induced seizure in mice and the probable role of nitric oxide
Keywords: آگوملاتین; Agomelatine; Seizure; Penthylenetetrazol; Nitric oxide; Mice
Agomelatine but not melatonin improves fatigue perception: A longitudinal proof-of-concept study
Keywords: آگوملاتین; Fatigue; Dopamine; Noradrenaline; Agomelatine; Melatonin;
Comparable efficacy and safety of 8 weeks treatment with agomelatine 25-50Â mg or fluoxetine 20-40Â mg in Asian out-patients with major depressive disorder
Keywords: آگوملاتین; MDD; major depressive disorder; MT; melatonin; 5-HT; serotonin; Agomelatine; Fluoxetine; Antidepressant; Asian population;
Agomelatine strongly interacts with zwitterionic DPPC and charged DPPG membranes
Keywords: آگوملاتین; Agomelatine; Membrane lipid; FTIR spectroscopy; DSC; Lipid structure;
A placebo-controlled study of three agomelatine dose regimens (10Â mg, 25Â mg, 25-50Â mg) in patients with major depressive disorder
Keywords: آگوملاتین; MDD; major depressive disorder; Agomelatine; Depression; Placebo; Dose regimen;
Impact de l'utilisation de l'agomélatine sur la consommation d'hypnotiques
Keywords: آگوملاتین; Agomélatine; Troubles du sommeil; Dépression; Hypnotiques; Ãtude cas-témoin; Agomelatine; Sleep disorders; Depression; Sedative hypnotics; Case-control study;
The efficacy of agomelatine in previously-treated depressed patients
Keywords: آگوملاتین; Agomelatine; Depression; Efficacy; Meta-analysis; Sertraline
Quantification and structural elucidation of potential impurities in agomelatine active pharmaceutical ingredient
Keywords: آگوملاتین; Agomelatine; Impurity; Quantification; Structural elucidation; RP-HPLC method
Investigation of physicochemical properties and in-vitro in-vivo evaluation of agomelatine polymorphs
Keywords: آگوملاتین; Agomelatine; Polymorphs; Intrinsic dissolution rate; Pharmacokinetics; IVIVC