دانلود مقالات ISI درباره AKR، آلدو کتو ردوکتاز + ترجمه فارسی

مهار انتراسیکلین ردوکتاز انسانی توسط امودین یک درمان احتمالی مقاومت انتراسیکلین

Inhibition of human anthracycline reductases by emodin — A possible remedy for anthracycline resistance

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; SDR, short-chain dehydrogenase/reductase; DAUN, daunorubicin; DOX, doxorubicin; DAUNOL, daunorubicinol; DOXOL, doxorubicinolAnthracycline resistance; Daunorubicin; Aldo-keto reductases; Short-chain dehydrogenases/reductases; Enzy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

بیان ژن و تجزیه و تحلیل پروتئور یک آلدو کتو ردوکتاز گوجه فرنگی جدید در پاسخ به تنش های محیطی

Gene expression and promoter analysis of a novel tomato aldo-keto reductase in response to environmental stresses

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; AsA, ascorbic acid; GalUAR, d-galacturonic acid reductase; GST, glutathione S-transferase; nt, nucleotideAldo-keto reductase; Abiotic stress; Gene expression; Plant hormone; Promoter assay; Solanum lycopersicum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

شناسایی ژنومیک مبتنی بر شناسه ردستاکس جدید استریدروسپورتی جدید از کاندیدا پاراپسلیوز برای کاهش بسیار زیادی از ترکیبات کربونیل

Genomic mining-based identification of novel stereospecific aldo-keto reductases toolbox from Candida parapsilosis for highly enantioselective reduction of carbonyl compounds

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; ORF, open reading frame; IPTG, isopropyl-β-d-thiogalactopyranoside; TCEP, Tris (2-carboxyethyl) phosphine; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresisAldo-keto reductase; Genomic mining; Toolbox; Enantiose

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Glutamate cysteine ligase and the age-related decline in cellular glutathione: The therapeutic potential of γ-glutamylcysteine

Keywords: AKR، آلدو کتو ردوکتاز; Glutathione; Aging; γ-glutamylcysteine; Oxidative stress; Glutamate cysteine ligase4-HNE, 4-hydroxynonenal; γ-GC, γ-glutamylcysteine; γ-GT, γ-glutamyl transpeptidase; AD, Alzheimer's disease; AKR, aldo-keto reductase; AP-1, activator protein-1; AP-2, acti

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Polymer–lipid hybrid nanoparticles synchronize pharmacokinetics of co-encapsulated doxorubicin–mitomycin C and enable their spatiotemporal co-delivery and local bioavailability in breast tumor

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; AUC, area under the curve; CL, total body clearance; cTnI, cardiac troponin I; DMPLN, doxorubicin and mitomycin C co-loaded polymer–lipid hybrid nanoparticles; DOX, doxorubicin; DOXOL, doxorubicinol; EPR, enhanced permeability an

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Protective roles of aldo-keto reductase 1B10 and autophagy against toxicity induced by p-quinone metabolites of tert-butylhydroquinone in lung cancer A549 cells

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; BHQ, tert-butylhydroquinone; C1, (Z)-2-(4-methoxyphenylimino)-7-hydroxy-N-(pyridin-2-yl)-2H-chromene-3-carboxamide; DMSO, dimethylsulfoxide; DPBS, Dulbecco’s phosphate-buffered saline; DTNB, 5,5′-dithiobis(2-nitrobenzoic acid); E

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Butylated hydroxyanisole induces distinct expression patterns of Nrf2 and detoxification enzymes in the liver and small intestine of C57BL/6 mice

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; ARE, antioxidant response element; BHA, butylated hydroxyanisole; BQ, tert-butylquinone; β-TrCP, β-transducin repeat-containing protein; GSK-3, glycogen synthase kinase-3; Gapdh, glyceraldehyde-3-phosphate dehydrogenase; GSH, red

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The aldo-keto reductases (AKRs): Overview

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; PG, prostaglandin; SDR, short-chain dehydrogenase reductase; nsSNP, non-synonymous single nucleotide polymorphism; SSH, succinic semialdehyde dehydrogenaseHydroxysteroid dehydrogenases; Potassium channels; Steroid 5β-reductase; Q

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Plant aldo-keto reductases (AKRs) as multi-tasking soldiers involved in diverse plant metabolic processes and stress defense: A structure-function update

Keywords: AKR، آلدو کتو ردوکتاز; ABA, abscisic acid; ADH, alcohol/aldehyde dehydrogenase; AKR, aldo-keto reductase; AOR, alkenal/one oxidoreductase; AR, aldose reductase; CHR, chalcone reductase; CHS, 6′-deoxychalcone synthase; DMA, deoxymugineic acid; DMAS, deoxymugineic acid synthase;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Stereoselective synthesis of (R)-phenylephrine using recombinant Escherichia coli cells expressing a novel short-chain dehydrogenase/reductase gene from Serratia marcescens BCRC 10948

Keywords: AKR، آلدو کتو ردوکتاز; ADH, alcohol dehydrogenase; AKR, aldo-keto reductase; DDBDH, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; DHMPR, dihydromonapterin reductase; Dro_ADH, D. melanogaster alcohol dehydrogenase; GDH, glucose 1-dehydrogenase B; HBDH, d-beta-hydroxybutyrate

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Structure–activity relationships studies of quinoxalinone derivatives as aldose reductase inhibitors

Keywords: AKR، آلدو کتو ردوکتاز; Quinoxalinone derivatives; Aldose reductase inhibitors; Structure–activity relationshipsALR2, aldose reductase; ALR1, aldehyde reductase; ARIs, aldose reductase inhibitors; AKR, aldo-keto reductase; NADPH, β-nicotinamide adenine dinucleotide phosphate red

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of aldo-keto reductases as NRF2-target marker genes in human cells

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; shNRF2, NRF2 knockdown cell line; sc, nonspecific control cell line; ARE, antioxidant-response element; ROS, reactive oxygen species; GSH, glutathione; NQO1, NAP(D)H: quinone oxidoreductase-1; GST, glutathione S-transferase; GCLC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Oxazaphosphorine bioactivation and detoxification: the role of xenobiotic receptors

Keywords: AKR، آلدو کتو ردوکتاز; ALDH, aldehyde dehydrogenase; AKR, aldo-keto reductase; AhR, aryl hydrocarbon receptor; BCRP, breast cancer resistance protein; CAA, chloroacetaldehyde; CAR, constitutive androstane receptor; CPA, cyclophosphamide; CYP, cytochrome P450; CMF, cyclophospham

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Formation of a 3,4-diol-1,2-epoxide metabolite of benz[a]anthracene with cytotoxicity and genotoxicity in a human in vitro hepatocyte culture system

Keywords: AKR، آلدو کتو ردوکتاز; BA, benz[a]anthracene; BA-3,4-diol-1,2-epoxide, benz[a]anthracene-3,4-diol-1,2-epoxide; CYP, cytochrome P450; AKR, aldo-keto reductase; ROS, reactive oxygen species; B[a]P, benzo[a]pyreneBenz[a]anthracene; Cytochrome P450; Aldo-keto reductase; Benz[a]anth

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Probing the inhibitor selectivity pocket of human 20α-hydroxysteroid dehydrogenase (AKR1C1) with X-ray crystallography and site-directed mutagenesis

Keywords: AKR، آلدو کتو ردوکتاز; HSD, hydroxysteroid dehydrogenase; AKR, aldo-keto reductase; AKR1C1, human 20α-hydroxysteroid dehydrogenase; S-Tetralol, S-(+)-1,2,3,4-tetrahydro-1-naphthol; GABAA, γ-aminobutyric acid type A; CPSA, 3-chloro-5-phenylsalicylic acid; DCSA, 3,5-dichlorosalic

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Activities of aldo-keto reductase 1 enzymes on two inhaled corticosteroids: Implications for the pharmacological effects of inhaled corticosteroids

Keywords: AKR، آلدو کتو ردوکتاز; ACTH, adrenocorticotropic hormone; AKR, aldo-keto reductase; AKR1D1, 5β-reductase; AKR1C1–4, ketosteroid reductases; BUD, budesonide; FLU, flunisolide; GR, glucocorticoid receptor; HSD, hydroxysteroid dehydrogenase; ICS, inhaled corticosteroid(s); 5α-R, 5

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1)

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; AKR1B1, aldose reductase; AKR1C1-1C4, human hydroxysteroid dehydrogenases; AKR1C9, rat 3α-hydroxysteroid dehydrogenase; AKR1D1, human steroid 5β-reductase; AKR1D2, rat steroid 5β-reductase; HSD, hydroxysteroid dehydrogenase; NSAI

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibitors of human 20α-hydroxysteroid dehydrogenase (AKR1C1)

Keywords: AKR، آلدو کتو ردوکتاز; HSD, hydroxysteroid dehydrogenase; AKR, aldo-keto reductase; AKR1C1, human 20α-hydroxysteroid dehydrogenase; AKR1C2, human type 3 3α-hydroxysteroid dehydrogenase; AKR1C3, human type 2 3α-hydroxysteroid dehydrogenase; AKR1C4, human type 1 3α-hydroxysteroid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The Drosophila carbonyl reductase sniffer is an efficient 4-oxonon-2-enal (4ONE) reductase

Keywords: AKR، آلدو کتو ردوکتاز; 1,4DHN, 1,4-dihydroxynon-2-ene; 1HNO, (E)1-hydroxynon-2-en-4-one; 4HNE, (E)-4-hydroxynon-2-enal; CBR, carbonyl reductase; 4ONE, (E)-4-oxonon-2-enal; AKR, aldo-keto reductase; HPLC, high pressure liquid chromatography; ROS, reactive oxygen species; SDR, sh

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Functional characterization of rose phenylacetaldehyde reductase (PAR), an enzyme involved in the biosynthesis of the scent compound 2-phenylethanol

Keywords: AKR، آلدو کتو ردوکتاز; AADC, aromatic amino acid decarboxylase; AKR, aldo-keto reductase; LDR, long-chain dehydrogenase/reductases; MDR, medium-chain dehydrogenase/reductases; PAld, phenylacetaldehyde; PAR, phenylacetaldehyde reductase; 2PE, 2-phenylethanol; l-Phe, l-phenylalan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Glyceraldehyde-3-phosphate dehydrogenase as a quinone reductase in the suppression of 1,2-naphthoquinone protein adduct formation

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; 1,4-BQ, 1,4-benzoquinone; CBB, Coomassie brilliant blue; DAN, 1,2-diacetoxynaphthalene; ESI, electrospray ionization; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GSH, glutathione; 1,2-NQ, 1,2-naphthoquinone; 1,2-NQH2, 1,2-di

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29

Keywords: AKR، آلدو کتو ردوکتاز; AhR, aryl hydrocarbon receptor; AKR, aldo-keto reductase; ARE, antioxidant response element; CYP1A1, cytochrome P450-dependent monooxygenase 1A1; Cox-2, cyclooxygenase-2; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; γ-GCS (GCLC), gamma-glutamylcystein

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Prostaglandin F2α suppresses early phase of adipogenesis, but is not associated with osteoblastogenesis in mouse mesenchymal stem cells

Keywords: AKR، آلدو کتو ردوکتاز; MSC, mesenchymal stem cells; AKR, aldo-keto reductase; PG, prostaglandin; COX, cyclooxygenase; TBP, TATA-binding protein; ALP, alkaline phosphatase; PGFS, PGF2α synthase; N.C., negative control; EIA, enzyme immunoassay; IBMX, 3-isobutyl-1-methylxanthine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

1,10-Phenanthroline stabilizes mRNA of the carcinogen-metabolizing enzyme, cytochrome P450 1a1

Keywords: AKR، آلدو کتو ردوکتاز; ActD, actinomycin D; AhR, aryl hydrocarbon receptor; AKR, aldo-keto reductase; BaP, benzo[a]pyrene; CHX, cycloheximide; CYP, cytochrome P450; DEPs, diesel exhaust particles; FFA, flufenamic acid; indo, indomethacin; 1-NP, 1-nitropyrene; PAHs, polycyclic a

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Structure-based optimization and biological evaluation of human 20α-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors

Keywords: AKR، آلدو کتو ردوکتاز; Aldo-keto reductase; 3-Bromo-5-phenylsalicylic acid; Cancer; Drug design; Human 20α-hydroxysteroid dehydrogenase; Human 3α-hydroxysteroid dehydrogenaseHSD, hydroxysteroid dehydrogenase; AKR, aldo-keto reductase; AKR1C1, human 20α-hydroxysteroid dehydrogen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; AhR, aryl hydrocarbon receptor; CES, carboxylesterase; CAR, constitutive androstane/activated receptor; CYP, cytochrome P450; CCRP, cytoplasmic CAR retention protein; CITCO, 6-(4-chlorophenyl) imidazo[2,1-b][1,3]thiazole-5-carbal

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

The CCAAT box binding transcription factor, nuclear factor-Y (NF-Y) regulates transcription of human aldo-keto reductase 1C1 (AKR1C1) gene

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; DDH, dihydrodiol dehydrogenase 1; PAH, polycyclic aromatic hydrocarbons; HSD, hydroxysteroid dehydrogenase; NRF2, nuclear factor erythroid-derived 2-related factor; ARE, human antioxidant response element; EA, ethacrynic acid; NF

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

The glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations

Keywords: AKR، آلدو کتو ردوکتاز; 11β-HSD, 11β-hydroxysteroid dehydrogenase; AKR, aldo-keto reductase; CYP450, cytochrome P450; ER, endoplasmic reticulum; G6P, glucose-6-phosphate; G6PT, endoplasmic reticulum glucose-6-phophate transporter; GR, glucocorticoid receptor; H6PDH, hexose-6-pho

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Structure–activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; SDR, short-chain dehydrogenase/reductaseAldo-keto reductase; Bile acid metabolism; Homology modelling; Docking; X-ray crystallography

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Vitamin A/retinoids signalling in the human lung

Keywords: AKR، آلدو کتو ردوکتاز; ADC, adenocarcinoma; AKR, aldo-keto reductase; ALDH, aldehyde dehydrogenase; at-RA, all-trans retinoic acid; at-retinol, all-trans retinol; CRABP, cellular retinoic acid-binding protein; CRBP, cellular retinol-binding protein; DBD, DNA-binding domain; IHC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; AR, aldose reductase; FGF, fibroblast growth factor; HSD, hydroxysteroid dehydrogenase; TBE, 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione; RT, reverse transcription; U, unit; FBS, fetal bovine serumAldo-keto reductase superfami

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Type 5 17β-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): Role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; PG, prostaglandin; APCI-MRM/MS, atmospheric pressure chemical ionization-multiple reaction monitoring/mass spectrometry; PGHS, PGH2 synthase; 17β-HSD, 17β-hydroxysteroid dehydrogenase; ER, estrogen receptor; PR, progesterone rece

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Activation of antioxidant defense during dehydration stress in the African clawed frog

Keywords: AKR، آلدو کتو ردوکتاز; GST, glutathione S-transferase; AKR, aldo-keto reductase; Nrf2, NF-E2 related factor 2; ARE, antioxidant response element; ROS, reactive oxygen species; NFE2L2, nuclear factor (erythroid-derived 2) like 2Xenopus laevis; Reactive oxygen species; Nrf2 trans

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

A novel NADPH-dependent aldehyde reductase gene from Saccharomyces cerevisiae NRRL Y-12632 involved in the detoxification of aldehyde inhibitors derived from lignocellulosic biomass conversion

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; DNA, deoxyribonucleic acid; HMF, 5-hydroxymethylfurfural; MDR, medium-chain dehydrogenase/reductase; NADPH, reduced nicotinamide adenine dinucleotide phosphate; ORF, open reading frame; qRT-PCR, real time quantitative reverse tra

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Biochemical and structural characterization of a short-chain dehydrogenase/reductase of Thermus thermophilus HB8: A hyperthermostable aldose-1-dehydrogenase with broad substrate specificity

Keywords: AKR، آلدو کتو ردوکتاز; SDR, short-chain dehydrogenase/reductase; AKR, aldo-keto reductase; MDR, medium-chain dehydrogenase/reductase; DrSDR, Deinococcus radiodurans SDR family oxidoreductase; TAD, T. thermophilus aldose 1-dehydrogenase; GlcD, glucose 1-dehydrogenase; RMSD, root

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells

Keywords: AKR، آلدو کتو ردوکتاز; 3α-diol, 5α-androstane-3α,17β-diol; 15Δ-PGJ2, 15-deoxy-Δ12,14-PGJ2; AKR, aldo-keto reductase; FP, prostaglandin F receptor; PG, prostaglandin; PGFS, prostaglandin F synthase; PI3K, phosphatidylinositol 3-kinaseAldo-keto reductase; Prostaglandin; Prostate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Pre-receptor regulation of the androgen receptor

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; AKR1C1, 20α(3α)-hydroxysteroid dehydrogenase; AKR1C2, human type 3 3α-hydroxysteroid dehydrogenase; AKR1C3, human type 2 3α-hydroxysteroid dehydrogenase, type 5 17β-hydroxysteroid dehydrogenase; AKR1C4, human type 1 3α-hydroxyste

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent m

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; HSD, hydroxysteroid dehydrogenase; CBM, N-(4-chlorobenzoyl)-melatonin; DHT, 5α-dihydrotestosterone, 3α-androstanediol, 5α-androstane-3α,17β-diol; PG, prostaglandin; PPARγ, peroxisome proliferator-activated receptor γ; COX, cycloo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis

Keywords: AKR، آلدو کتو ردوکتاز; AhR, aryl hydrocarbon receptor; AKR, aldo-keto reductase; B[a]P, benzo[a]pyrene; JNK, c-Jun NH2-terminal kinase; CYP, cytochrome P450; DEP, diesel exhaust particle; ERK, extracellular signal-regulated kinase; NB, nitrobenzene; αNF, α-naphthoflavone; NM, n

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Identification of the molecular switch that regulates access of 5α-DHT to the androgen receptor

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; AR, androgen receptor; BPH, benign prostatic hyperplasia; 5α-DHT, 5α-dihydrotestosterone; 3α-diol or 3α-androstanediol, 5α-androstane-3α,17β-diol; ERAB, endoplasmic reticulum β-peptide binding protein; HSD, hydroxysteroid dehydro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Functional studies of aldo-keto reductases in Saccharomyces cerevisiae

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; AR, aldose reductase; GPD, glyceraldehyde 3-phosphate dehydrogenase; IEC, ion exchange chromatography; ORF, open reading frame; YPD, yeast peptone dextrosesynthetic completeAldo-keto reductase; Aldose reductase; Saccharomyces cer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

An approach to evaluate two-electron reduction of 9,10-phenanthraquinone and redox activity of the hydroquinone associated with oxidative stress

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; AZQ, 2,5-ethyl(carboethoxyamino)3,6-diaziridinyl-1,4-benzoquinone; DAP, 9,10-diacetoxyphenanthrene; DEP, diesel exhaust particles; DMPO, 5,5-dimethyl-1-pyrroline N-oxide; DMSO, dimethyl sulfoxide; DNPH, 2,4-dinitrophenylhydrazine

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Mouse 17α-Hydroxysteroid Dehydrogenase (AKR1C21) Binds Steroids Differently from other Aldo-keto Reductases: Identification and Characterization of Amino Acid Residues Critical for Substrate Binding

Keywords: AKR، آلدو کتو ردوکتاز; m17α-HSD, mouse 17α-hydroxysteroid dehydrogenase; AKR, aldo-keto reductase; Δ4, androstenedione; epi-T, epi-testosterone; HSD, hydroxysteroid dehydrogenase; SDR, short chain dehydrogenase/reductase; h3α-HSD3, human type 3 3α-hydroxysteroid dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Depot-specific prostaglandin synthesis in human adipose tissue: A novel possible mechanism of adipogenesis

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; BMI, body mass index; FCS, fetal calf serum; HSD, hydroxysteroid dehydrogenase; hPGT, human prostaglandin transporter; IL-1β, interleukin 1β; iNOS, inducible NO synthase; OM, omental; PG, prostaglandin; PGHS1, prostaglandin synth

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Mouse aldo-keto reductase AKR7A5 protects V79 cells against 4-hydroxynonenal-induced apoptosis

Keywords: AKR، آلدو کتو ردوکتاز; 4-HNE, 4-hydroxynonenal; AKR, aldo-keto reductase; HGPRT, hypoxanthine guanine phosphoribosyl transferase; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide4-Hydroxynonenal; Aldo-keto reductase; V79 cells; Apoptosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Benzo[a]pyrene and glycine N-methyltransferse Interactions: Gene expression profiles of the liver detoxification pathway

Keywords: AKR، آلدو کتو ردوکتاز; PAH, polycyclic aromatic hydrocarbon; BaP, Benzo[a]pyrene; CYP P450, cytochrome P450; BPDE, BaP-7,8-diol 9,10-epoxide; CRR, common reference RNA; GST, glutathione S-transferase; AKR, aldo-keto reductase; UGT, UDP glycosyltransferase; ALDH, aldehyde dehydr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Aldo-keto reductase (AKR) 1C3: Role in prostate disease and the development of specific inhibitors

Keywords: AKR، آلدو کتو ردوکتاز; Adione, Δ4-androstene-3,17-dione; AhR, aryl hydrocarbon receptor; AKR, aldo-keto reductase; 3α-androstanediol, 5α-androstane-3α,17β-diol; 3β-androstanediol, 5α-androstane-3β,17β-diol; AR, androgen receptor; BP, benzo[a]pyrene; BPH, benign prostatic hyperp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Cigarette smoke condensate induces cytochromes P450 and aldo-keto reductases in oral cancer cells

Keywords: AKR، آلدو کتو ردوکتاز; AKR, aldo-keto reductase; ANOVA, analysis of variance; CSC, cigarette smoke condensate; CYP, cytochrome P450; DMEM, Dulbecco modified Eagle's medium; DMSO, dimethyl sulfoxide; FDR, false discovery rate; NHEK, normal human epidermal keratinocytes; OSCC, or

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه