Keywords: Heterotopic ossification; Fibrodysplasia Ossificans Progressiva; Chondrogenesis and osteogenesis; Retinoid signaling; Retinoid nuclear receptors; ALK2; BMP signaling; Hereditary Multiple Exostoses; Multiple Osteochondromas;
مقالات ISI (ترجمه نشده)
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Keywords: ALKs; activin receptor-like (type I) kinases; BMP; bone morphogenetic protein; BMPRII; BMP type II receptor; FKBP12; FK506-binding protein 12â¯kDa; FOP; Fibrodysplasia Ossificans Progressiva; AMPK; AMP-activated protein kinase; SMKI; small molecule kinas
Imaging assessment of fibrodysplasia ossificans progressiva: Qualitative, quantitative and questionable
Keywords: FOP; fibrodysplasia ossificans progressiva; CT; computed tomography; HO; heterotopic bone; ACVR1; activin A type I receptor; ALK2; activin-like kinase2; mSv; millisievert; AP; anterioposterior; MRI; magnetic resonance imaging; US; Ultrasonography; 99Â m T
Drosophila models of FOP provide mechanistic insight
Keywords: Fibrodysplasia Ossificans Progressiva; ACVR1; ALK2; Sax; BMP signaling; Heterotopic ossification;
Stem cells and heterotopic ossification: Lessons from animal models
Keywords: Animal models; Heterotopic ossification; Stem cells; Progenitor cells; Fibrodysplasia ossificans progressiva; FOP; ACVR1; ALK2; Activin; BMP; Fibro/adipogenic progenitors; FAPs; Satellite cell; Endothelium; Skeletal muscle; Tendon; PDGFRα; TIE2; Scleraxi
ALK3 undergoes ligand-independent homodimerization and BMP-induced heterodimerization with ALK2
Keywords: BMP; Bone morphogenetic protein; ALK2; Activin receptor type-1; ALK3; Activin Receptor-like Kinase; IL; Interleukin; Smad; Small Mothers Against Decapentaplegic Homolog; JAK; Janus kinase; Stat3; Signal transducer and activator of transcription; Cre; caus
Molecular mechanisms for activation of mutant activin receptor-like kinase 2 in fibrodysplasia ossificans progressiva
Keywords: Fibrodysplasia ossificans progressiva; BMP; ALK2; Receptors;
Homocysteine upregulates hepcidin expression through BMP6/SMAD signaling pathway in hepatocytes
Keywords: Hyperhomocysteinemia; Homocysteine; Hepcidin; BMP6/SMAD; Hepatocytes; ALK2; activin receptor-like kinase 2; ALK3; activin receptor-like kinase 3; ALK6; activin receptor-like kinase 6; BMP4; bone morphogenetic protein 4; BMP6; bone morphogenetic protein 6;
ACVR1-Fc suppresses BMP signaling and chondro-osseous differentiation in an in vitro model of Fibrodysplasia ossificans progressiva
Keywords: Fibrodysplasia ossificans progressiva; Heterotopic ossification; BMP signaling; ACVR1; ALK2;
Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders
Keywords: ACVR1; ALK2; Fibrodysplasia Ossificans Progressiva; Diffuse Intrinsic Pontine Gliomas; Orphan diseases; BMP signaling
BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse
Keywords: BMP; Bmpr1a; Bmpr1b; Acvr1; Alk2; Alk3; Alk6; Smad4; Sox9; Cartilage; Mesenchymal condensation; Mouse;
BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints
Keywords: Nfatc1; ALK2; Acvr1; BMP receptor; Heterotopic ossification; Fibrodysplasia ossificans progressive; FOP; Cartilage; Bone; Endochondral ossification;
The phenotype and genotype of fibrodysplasia ossificans progressiva in China: A report of 72 cases
Keywords: Fibrodysplasia ossificans progressiva; Heterotopic ossification; Bone morphogenetic protein; ACVR1; ALK2;
Structural basis for specificity of TGFβ family receptor small molecule inhibitors
Keywords: ALK5; SB431542; ALK2; Dorsomorphin; A8301
Insights from a rare genetic disorder of extra-skeletal bone formation, fibrodysplasia ossificans progressiva (FOP)
Keywords: ACVR1; ALK2; BMP type I receptor; Fibrodysplasia ossificans progressiva (FOP); Bone morphogenetic protein (BMP);
Fibrodysplasia ossificans progressiva
Keywords: fibrodysplasia ossificans progressiva (FOP); heterotopic ossification; bone morphogenetic protein; BMP; ACVR1; ALK2
BMP6 is axonally transported by motoneurons and supports their survival in vitro
Keywords: BMPRII; ALK2; ALK3; Axonal transport; Glia; Motoneuron
Zebrafish Bmp4 regulates left–right asymmetry at two distinct developmental time points
Keywords: Bmp4; Alk2; Alk8; Laterality; Cardiac development; Heterotaxia; Zebrafish
n-Alkane and clofibrate, a peroxisome proliferator, activate transcription of ALK2 gene encoding cytochrome P450alk2 through distinct cis-acting promoter elements in Candida maltosa
Keywords: Candida maltosa; Yeast; Cytochrome P450alk; Clofibrate; Peroxisome proliferator; ALK2; Gene expression; Promoter element; CRE2;
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart
Keywords: Atrioventricular cushion; ALK2; BMP; TGF-β; Transformation; Cardiac development;