Keywords: ALK5; activin-like kinase 5; d; days; ECs; endothelial cells; EPCs; endothelial progenitor cells; FITC; fluorescein isothiocyanate; GDF11; growth differentiation factor 11; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; I/R; ischemia/reperfusion; MCA; m
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: ANOVA; analysis of variance; ABP; arterial blood pressure; ALK5; activin-like kinase 5; cVNS; cervical vagus nerve stimulation; CCA; common carotid artery; d; day/days; ECs; endothelial cells; EPCs; endothelial progenitor cells; ELISA; enzyme linked immun
Keywords: α-SMA; α-smooth muscle actin; ALK1; activin receptor-like kinase 1; ALK5; activin receptor-like kinase 5; ANOVA; analysis of variance; ECM; extracellular matrix; Eng; endoglin; ICAM-1; intercellular cell adhesion molecule-1; NO; non-obstructed; O; obstr
Keywords: TGF-β; transforming growth factor-β; MSTN; myostatin gene; LAP; latency-associated peptide; FLRG; follistatin-related gene peptide; FSTL-3; follistatin like 3; GASP; growth/differentiation factor-associated serum protein; LTBP; latent TGF-β-binding pro
Galangin's potential as a functional food ingredient
Keywords: Galangin; Propolis; Alpinia officinarum; Functional food ingredient; Polypharmacology; Flavonoid; AChE; acetylcholinesterase; AD; Alzheimer's disease; ADME; Administration, Distribution, Metabolism and Excretion; AHR; airway hyperresponsive; AhR; aryl h
EW-7197, an activin-like kinase 5 inhibitor, suppresses granulation tissue after stent placement in rat esophagus
Keywords: ALK5; activin-like kinase 5; ECM; extracellular matrix; EMT; epithelial mesenchymal transition; EW-7197; N-[[4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-fluoroaniline; SEMS; self-expanding metallic stent; TGF
ALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles
Keywords: Transforming growth factor beta receptor I; Protein kinase; Inhibitor; Substituted pyrrolo[1,2-b]pyrazoles; ALK5; activin A receptor type II-like kinase; DPP; 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole; TGFβ; transforming growth factor beta; TGFB
Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice
Keywords: Osteoarthritis; Chondrocytes; ALK5; PRG4; CREB;
Novel ALK5 inhibitor TP0427736 reduces TGF-βãinduced growth inhibition in human outer root sheath cells and elongates anagen phase in mouse hair follicles
Keywords: TGF-β; ALK5; Androgenic alopecia; Smad2 phosphorylation; Anagen phase;
Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1
Keywords: miRNA; microRNA; TGF-β1; transforming growth factor-β1; Smad; mammalian homologue of Drosophila Mad and C. elegans Sma; mRISC; miRNA-induced silencing complex; EMT; epithelial-mesenchymal transformation; BSA; bovine serum albumin; NC; negative control;
Follistatin-like 1 protects cardiomyoblasts from injury induced by sodium nitroprusside through modulating Akt and Smad1/5/9 signaling
Keywords: Follistatin-like 1; Sodium nitroprusside; Nitric oxide; Apoptosis; Akt signaling; BMP/Smad1/5/9 signaling; ALK5; activin receptor-like kinase 5; BMP; bone morphogenetic protein; DMEM; Dulbecco's modified Eagle's medium; FSTL1; Follistatin-like 1; PCR; pol
Design, synthesis and optimization of novel Alk5 (activin-like kinase 5) inhibitors
Keywords: Alk5; Inhibitors; Activin; Kinase; Transforming; Growth; Factor; SBDD;
BMP-9 dependent pathways required for the chondrogenic differentiation of pluripotent stem cells
Keywords: Chondrogenesis; BMP; Collagen; ALK5; Noggin;
Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1
Keywords: ALK5; activin receptor-like kinase 5; Bcl-xL; B-cell lymphoma-extra large; DISC; death inducing signaling complex; EGF; epidermal growth factor; ERK; extracellular signal-regulated kinase; FADD; Fas-associated protein with death domain; FLIP; FLICE-like i
Identification of bone morphogenetic protein 9 (BMP9) as a novel profibrotic factor in vitro
Keywords: BMP9; ALK1; ALK5; Fibroblasts; Fibrosis; Extracellular matrix proteins;
Role of ALK5/Smad2/3 and MEK1/ERK Signaling in Transforming Growth Factor Beta 1–modulated Growth, Collagen Turnover, and Differentiation of Stem Cells from Apical Papilla of Human Tooth
Keywords: ALK5; alkaline phosphatase; ERK; signal transduction; Smad2; stem cells from apical papilla; transforming growth factor beta
Salusin-β contributes to vascular remodeling associated with hypertension via promoting vascular smooth muscle cell proliferation and vascular fibrosis
Keywords: AC; adenylate cyclase; ALK5; activin receptor-like kinase 5; Ang II; angiotensin II; CCK-8; cell counting kit-8 kits; CREB; cAMP response element binding protein; CTGF; connective tissue growth factor; ECM; extracellular matrix; EGF; epidermal growth fact
Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction
Keywords: Epilepsy; Albumin; TGF-β; Synaptogenesis; Blood–brain barrier (BBB); Seizures; Astrocytes; Post-insult epilepsy (PIE); Post-traumatic epilepsy (PTE); ALK5
Treatment of cholestatic fibrosis by altering gene expression of Cthrc1: Implications for autoimmune and non-autoimmune liver disease
Keywords: Hepatic fibrosis; Cholestatic liver fibrosis; Hepatic stellate cell; Anti-fibrotic treatment; TGF-β pathway; Cthrc1; collagen triple helix repeat containing-1; TGF-β; transforming growth factor-β; CBDL; common bile duct ligation; DDC; 3, 5-diethoxycarb
Design, synthesis and evaluation of small molecule imidazo[2,1-b][1,3,4]thiadiazoles as inhibitors of transforming growth factor-β type-I receptor kinase (ALK5)
Keywords: Synthesis imidazo [2,1-b][1,3,4]thiadiazole; ALK5; XP docking; Lipinski's rule
An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial–mesenchymal transition
Keywords: Transforming growth factor-β (TGF-β); ALK5; IN-1130; Breast cancer; Metastasis
Cigarette smoke-induced alveolar epithelial-mesenchymal transition is mediated by Rac1 activation
Keywords: EMT; epithelial-mesenchymal transition; COPD; chronic obstructive pulmonary disease; CSE; cigarette smoke extract; TGF-β1; transforming growth factor β1; α-SMA; α-smooth muscle actin; MMP-9; matrix metalloproteinases-9; ATNA; anti-TGF-β1 neutralizi
Original ResearchFull Report: Basic and Translational-Alimentary TractT-Helper 2 Cytokines, Transforming Growth Factor β1, and Eosinophil Products Induce Fibrogenesis and Alter Muscle Motility in Patients With Eosinophilic Esophagitis
Keywords: Primary Human Cells; Transmural Disease; Swallowing; Immune Regulation; ALK5; activin-like kinase 5; ECM; extracellular matrix; EoE; eosinophilic esophagitis; EPX; eosinophil peroxidase; FN; fibronectin; HCMC; human cord blood-derived mast cells; HEF; h
Synthesis and biological evaluation of 1,2,4-trisubstituted imidazoles as inhibitors of transforming growth factor-β type I receptor (ALK5)
Keywords: Transforming growth factor β; ALK5; Kinase inhibitor; Imidazole derivatives;
Human xylosyltransferase-I - A new marker for myofibroblast differentiation in skin fibrosis
Keywords: ALK5; transforming growth factor-β receptor I; α-SMA/ACTA2; alpha-smooth muscle actin; Dpm; disintegrations per minute; GAG; glycosaminoglycan; NHDF; normal human dermal fibroblast; RT-PCR; quantitative real-time pcr; TGF-β1; transforming growth factor
Synthesis and biological evaluation of 1-(6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)-1,2,3-triazoles as transforming growth factor-β type 1 receptor kinase inhibitors
Keywords: ALK5; TGF-β type 1 receptor kinase; Anticancer; Click chemistry; 1,2,3-Triazole
Expression of growth differentiation factor 9 (GDF9), ALK5, and claudin-11 in adult alpaca testis
Keywords: Adult alpaca; Testis; Spermatogenesis; Growth differentiation factor 9; ALK5; Claudin-11
Design, synthesis, and biological evaluation of novel 2-pyridinyl-[1,2,4]triazoles as inhibitors of transforming growth factor β1 type 1 receptor
Keywords: 2-Pyridinyl-[1,2,4]triazoles; Inhibitors; TGF-β1 type 1 receptor; ALK5
Structural basis for specificity of TGFβ family receptor small molecule inhibitors
Keywords: ALK5; SB431542; ALK2; Dorsomorphin; A8301
Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors
Keywords: Transforming growth factor-β; ALK5; P38MAP Kinase; Liver fibrosis
Synthesis and biological evaluation of 1,2,4-trisubstituted imidazoles and 1,3,5-trisubstituted pyrazoles as inhibitors of transforming growth factor β type 1 receptor (ALK5)
Keywords: Transforming growth factor bata; ALK5; Kinase inhibitor
Diabetes-relevant regulation of cultured blood outgrowth endothelial cells
Keywords: Alk1; Alk5; TGFβ; Endothelial cell; Apoptosis; Angiogenesis
IN-1130, a Novel Transforming Growth Factor-β Type I Receptor Kinase (Activin Receptor-like Kinase 5) Inhibitor, Promotes Regression of Fibrotic Plaque and Corrects Penile Curvature in a Rat Model of Peyronie's Disease
Keywords: Peyronie's Disease; Fibrosis; Transforming Growth Factor-Beta; ALK5; IN-1130;
TGF-β type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner
Keywords: TGF-β; Alk5; Craniofacial development; Mouse; Mandible; Tooth
Inhibition of activin receptor-like kinase 5 attenuates Bleomycin-induced pulmonary fibrosis
Keywords: ALK5; TGF-beta; Smad proteins; CTGF; Myofibroblast; Type I collagen; Type III collagen; Fibronectin
IN-1130, a novel transforming growth factor-β type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy
Keywords: IN-1130; ALK5; TGF-β; Renal fibrosis; UUO
Epithelial and ectomesenchymal role of the type I TGF-β receptor ALK5 during facial morphogenesis and palatal fusion
Keywords: Alk5; Cleft face; Cleft palate; Cranial neural crest; Craniofacial malformation; Mandible; Palatal fusion