دانلود مقالات ISI درباره oligonucleotide antisense + ترجمه فارسی

یک روش فلوئورسانس یک مرحله ای ساده برای کمبود ناخالصیهای دامیامیتی تک پایه کم در الیگونوکوتیدهای مصنوعی

A facile one-step fluorescence method for the quantitation of low-content single base deamination impurity in synthetic oligonucleotides

Keywords: oligonucleotide antisense; ASO; antisense oligonucleotide; 2′-MOE; 2′-O-methoxyethyl; MB; molecular beacon; PS; pure sequence; DA; deamination marker; cPS; complementary pure sequence; Antisense oligonucleotide; Molecular beacon; Competitive hybridization; Deamination;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

آنتاگونیستی پروتئین مورفوژنیک استخوان 4 موجب تشدید پیشرفت بیماری در یک مدل موش صحرایی از کمردرد جانبی آمیوتروفی

Antagonizing bone morphogenetic protein 4 attenuates disease progression in a rat model of amyotrophic lateral sclerosis

Keywords: oligonucleotide antisense; ALS; Amyotrophic lateral sclerosis; Antisense oligonucleotide; Astrocyte; BMP; Bone morphogenetic protein; Motor neuron; Neuroinflammation; Non-cell autonomous; SOD1;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

فیبروز کبدی: عوامل ضد انعقادی مستقیم و درمان های هدفمند

Liver fibrosis: Direct antifibrotic agents and targeted therapies

Keywords: oligonucleotide antisense; ASO; antisense oligonucleotide; ECM; extracellular matrix; DDR; discoidin domain receptor; FAP; fibroblast activation protein; HSC; hepatic stellate cell(s); MF; myofibroblast(s); Lox; lysyl oxidase; Loxl; lysyl oxidase-like; MMP; matrix metalloproteinase

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

مقاله پژوهشی توسعه یک روش کاتتریزاسیون ساده، سریع و قوی در موش صحرایی

Research articleDevelopment of a simple, rapid, and robust intrathecal catheterization method in the rat

Keywords: oligonucleotide antisense; Intrathecal; Drug delivery; Catheter; Antisense oligonucleotide; Rat; Cerebral spinal fluid; Thecal sack; Subarachnoid space;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

گیرنده پرولاکتین در سرطان سینه و پروستات هدف قرار دادن: بینش جدید به یک چالش قدیمی است

Prolactin receptor targeting in breast and prostate cancers: New insights into an old challenge

Keywords: oligonucleotide antisense; ADT; androgen deprivation therapy; AR; androgen receptor; ASO; antisense oligonucleotide; CARN; castration-resistant Nkx3.1 expressing cells; CK; cytokeratin; CRPC; castration-resistant prostate cancer; DMBA; 7,12-dimethylbenz[a]anthracene; ECM; extracell

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2017 سفارش ترجمه

نظرسنجی ها و رفتارهای سالم: 2015

ReviewEndogenous Opiates and Behavior: 2015

Keywords: oligonucleotide antisense; Ach; acetylcholine; ACL; anterior cruciate ligament; ACTH; adrenocorticotrophic hormone; AMP; adenosine monophosphate; AMPK; 5′adenosine monophosphate-activated protein kinase; AS ODN; antisense oligonucleotide; BDNF; brain-derived neurotrophic factor;

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2017 سفارش ترجمه

بیماری هانتینگتون: به روز رسانی استراتژی های درمانی

Huntington's disease: An update of therapeutic strategies

Keywords: oligonucleotide antisense; HD; Huntington's disease; htt gene; huntingtin gene; HDACi; histone deacetylase inhibitors; RNAi; RNA interference; ASO; antisense oligonucleotide; Tgasei; transglutaminase inhibitors; Huntington's disease (HD); htt gene; Histone deacetylase inhibitors (H

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

وسیله نقلیه تحویل نوکلئوتیدی خوراکی که هدف ماکروفاژهای کولون برای درمان بیماری التهابی روده است

An orally administrated nucleotide-delivery vehicle targeting colonic macrophages for the treatment of inflammatory bowel disease

Keywords: oligonucleotide antisense; Inflammatory bowel disease; Colonic macrophages; TNF-α; Antisense oligonucleotide; Targeting delivery

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

حوضچه های کاتیونی براساس سورفکتانت های غیر یونیک و آمینولیپیدهای مصنوعی به طور متوسط ​​تحویل الیگونوکلئوتید های آنتیسنس را به سلول های پستاندار

Cationic vesicles based on non-ionic surfactant and synthetic aminolipids mediate delivery of antisense oligonucleotides into mammalian cells

Keywords: oligonucleotide antisense; Cationic lipids; Cationic vesicles; Non-ionic surfactant vesicles; Antisense oligonucleotide; Antisense therapy; Gene delivery;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

پیشرفت های اخیر در داروسازی برای افزایش هیپرگلیسیریدمی

Recent advances in pharmacotherapy for hypertriglyceridemia

Keywords: oligonucleotide antisense; AAV1; adeno-associated virus serotype 1; ACC; American College of Cardiology; ACCELERATE; A Study of Evacetrapib in High-Risk Vascular Disease; ACCORD; Action to Control Cardiovascular Risk in Diabetes; ADA; American Diabetes Association; AMP; adenosine m

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

آتروفی عضلانی ستون فقرات: به روز رسانی در مورد پیشرفت درمانی

Spinal muscular atrophy: An update on therapeutic progress

Keywords: oligonucleotide antisense; ALS; amyotrophic lateral sclerosis; ASO; antisense oligonucleotide; BBB; blood brain barrier; CREB; cyclic AMP response element binding protein; FDA; Food and Drug Administration; GSK-3; glycogen synthase kinase 3; HDAC; histone deacetylase; hnRNP A1; het

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

تلقیح درمان برای بیماری عصبی-عضلانی

Splicing therapy for neuromuscular disease

Keywords: oligonucleotide antisense; 2′OMePS; 2′-O-methyl phosphorothioate; 2′MOE-PS; 2′-O-methoxyethyl phosphorothioate; AON; antisense oligonucleotide; CPP; cell-penetrating peptide; DMD; Duchenne muscular dystrophy; PMO; phosphorodiamidate morpholino; PPMO; peptide-conjugated phos

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2013 سفارش ترجمه

Single-center experience with intrathecal administration of Nusinersen in children with spinal muscular atrophy type 1

Keywords: oligonucleotide antisense; Spinal muscular atrophy; Lumbar puncture; Nusinersen; ASO; antisense oligonucleotide; CHOP INTEND; Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders; CNS; central nervous system; CSF; cerebrospinal fluid; EAP; expanded access prog

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Therapeutic silencing of FSP27 reduces the progression of atherosclerosis in Ldlr-/- mice

Keywords: oligonucleotide antisense; FSP27; Atherosclerosis; Obesity; Hypertriglyceridemia; Antisense therapy; ASO; antisense oligonucleotide; CVD; cardiovascular disease; CIDEC; cell death-inducing DFFA-like effector C; FSP27; fat-specific protein 27; gWAT; gonadal white adipose tissue; HDL

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal

Keywords: oligonucleotide antisense; Arg1; Arginase 1; α-SMA; alpha-smooth muscle actin; ASO; antisense oligonucleotide; BW; body weight; CCL2; chemokine (C-C motif) ligand 2; CCl4; carbon tetrachloride; Col1a1; procollagen α1(I) transcript; DAPI; 4,6-diamidino-2-phenylindole; DKO; doubl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

A randomized placebo-controlled phase 3 trial of an antisense oligonucleotide, drisapersen, in Duchenne muscular dystrophy

Keywords: oligonucleotide antisense; Duchenne muscular dystrophy; Drisapersen; Dystrophin; Antisense oligonucleotide; Exon skipping; six-minute walking distance;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Gene-based antiangiogenic applications for corneal neovascularization

Keywords: oligonucleotide antisense; cornea; neovascularization; angiogenesis; gene therapy; vascular endothelial growth factor; antisense oligonucleotide; miRNA;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Antidepressant-like actions by silencing of neuronal ELAV-like RNA-binding proteins HuB and HuC in a model of depression in male mice

Keywords: oligonucleotide antisense; Adult neurogenesis; Depression; ELAV-Like RBP; Hippocampal CA3 region; Sucrose preference test; Tail suspension test; aODN; antisense oligonucleotide; BDNF; brain-derived neurotrophic factor; CREB; cyclic-AMP response element-binding protein; DG; dentate

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Angubindin-1; Blood-brain barrier; Tricellular tight junction; Angulin-1; Tricellulin;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Transdermal immunomodulation: Principles, advances and perspectives

Keywords: oligonucleotide antisense; AD; atopic dermatitis; AHR; airway hyper responsiveness; APCs; antigen-presenting cells; AS-ODN; antisense oligonucleotide; BCG; Bacillus Calmette-Guérin; CTLs; cytotoxic T cells; dDCs; dermal dendritic cells; DfE; Dermatophagoides farinae extract; EAE;

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Effect of mipomersen on LDL-cholesterol in patients with severe LDL-hypercholesterolaemia and atherosclerosis treated by lipoprotein apheresis (The MICA-Study)

Keywords: oligonucleotide antisense; Lipoprotein; Familial hypercholesterolaemia; Antisense oligonucleotide; Apolipoprotein B;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

The transient receptor potential ankyrin-1 mediates mechanical hyperalgesia induced by the activation of B1 receptor in mice

Keywords: oligonucleotide antisense; AS-ODN; antisense oligonucleotide; DABK; des-Arginine9-bradykinin; DALBK; des-Arginine9-[Leucine8]-bradykinin; Iba-1; ionized calcium binding adaptor molecule; Mrgprs; Mas-related GPCR; MM-ODN; mismatch oligonucleotide; PAR-2 and PAR-4; proteinase-activat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Feature ArticleHER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug

Keywords: oligonucleotide antisense; HER2+ breast cancer; Polymer nanoconjugate; Trastuzumab mimetic peptide; 8-arm starPEG; Polymalic acid; AHNP; anti-HER2/neu peptide; Alexa; Alexa Fluor 680 (fluorescent dye); anti-TfR; anti-transferrin receptor; AON; antisense oligonucleotide; ATCC; Ameri

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Silencing of the RNA-binding protein HuR attenuates hyperalgesia and motor disability in experimental autoimmune encephalomyelitis

Keywords: oligonucleotide antisense; Multiple sclerosis; Central nervous system; Neuropathic pain; HuR; Relapsing-remitting experimental autoimmune encephalomyelitis; aODN; antisense oligonucleotide; dODN; degenerate oligonucleotide; ELAV protein; embryonic lethal abnormal vision protein; GF

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Alternative polyadenylation expands the mRNA isoform repertoire of human CD46

Keywords: oligonucleotide antisense; 5′ss; 5′ splice site; 3′RACE; 3′ Rapid Amplification of cDNA Ends; 3′UTR; 3′ UnTranslated Region; APA; Alternative PolyAdenylation; ASO; AntiSense Oligonucleotide; CCP; Complement Control Protein; CD46; Cluster of Differentiation gene 46; CD46

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Inhaled ENaC antisense oligonucleotide ameliorates cystic fibrosis-like lung disease in mice

Keywords: oligonucleotide antisense; Cystic fibrosis; ENaC; Antisense oligonucleotide; Aerosol;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Comparison of ambulatory capacity and disease progression of Duchenne muscular dystrophy subjects enrolled in the drisapersen DMD114673 study with a matched natural history cohort of subjects on daily corticosteroids

Keywords: oligonucleotide antisense; Duchenne muscular dystrophy; Antisense oligonucleotide; Comparative study; Exercise test; Dystrophin synthesis; Drug therapy;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Knocking down amygdalar PTP1B in diet-induced obese rats improves insulin signaling/action, decreases adiposity and may alter anxiety behavior

Keywords: oligonucleotide antisense; Amygdala; PTP1B; Insulin; Anxiety; Obesity; Akt; protein kinase B; ASO; antisense oligonucleotide; BAT; brown adipose tissue; CeA; central nucleus of the amygdala; CNS; central nervous system; EPM; elevated plus maze; ER; endoplasmatic reticulum; FI; food

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Oligonucleotide-based pharmaceuticals: Non-clinical and clinical safety signals and non-clinical testing strategies

Keywords: oligonucleotide antisense; Antisense oligonucleotide; siRNA; Aptamer; Toxicity; Immunostimulation; Immunosuppression; Pharmacokinetics; Non-clinical; ALP; alkaline phosphatase; ALT; alanine aminotransferase; APTT; activated partial thromboplastin time; AST; aspartate aminotransfera

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewTargeting telomerase and telomeres to enhance ionizing radiation effects in in vitro and in vivo cancer models

Keywords: oligonucleotide antisense; TMM; telomere maintenance mechanism; T/TTC; telomere/telomerase targeting compound; G4; G-quadruplex; DSB; double strand break; ALT; alternative lengthening of telomeres; GBM; glioblastoma multiforme; AS-ODN; antisense oligonucleotide; TIF; telomere-induc

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

'Dual' peptidyl-oligonucleotide conjugates: Role of conformational flexibility in catalytic cleavage of RNA

Keywords: oligonucleotide antisense; RNA cleavage; Peptidyl-oligonucleotide conjugate; Supramolecular self-assembly; Hybridization; Conformation; ASO; antisense oligonucleotide; DC; dual conjugate; POC; peptidyl-oligonucleotide conjugate; FITC; fluorescein isothiocyanate; MALDI; matrix-assis

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Clinical potential of oligonucleotide-based therapeutics in the respiratory system

Keywords: oligonucleotide antisense; AGO; Argonaute; ASO; antisense oligonucleotide; CCR3; C-C chemokine receptor 3; CPP; cell penetrating peptide; COPD; chronic obstructive pulmonary disease; CD; cluster designation; GMCSF; granulocyte monocyte-colony stimulating factor; IL; interleukin;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy

Keywords: oligonucleotide antisense; (up to 6) Seckel syndrome-1; Exonic splicing silencer; modified U1snRNA; Antisense oligonucleotide; correction approaches;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor-Rac1 Activation to Inhibit Keratinocyte Motility

Keywords: oligonucleotide antisense; AS; antisense oligonucleotide; GCS; glucosylceramide synthase; GCSI; glucosylceramide synthase inhibitor; GM3S; ganglioside GM3 synthase; IGF-1; insulin-like growth factor-1; IGF1R; insulin-like growth factor-1 receptor; IR; insulin receptor; M2D3; GM2/GD

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis of antisense oligonucleotides containing acyclic alkynyl nucleoside analogs and their biophysical and biological properties

Keywords: oligonucleotide antisense; Acyclic nucleoside; Antisense oligonucleotide; Alkyne; RNase H; Thermal stability; Nuclease resistance;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Noninvasive delivery of oligonucleotide by penetratin-modified polyplexes to inhibit protein expression of intraocular tumor

Keywords: oligonucleotide antisense; Intraocular drug delivery; Antisense oligonucleotide; Penetratin; Polyplex; Luciferase expression;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Evolution, expression analysis, and functional verification of Catharanthus roseus RLK1-like kinase (CrRLK1L) family proteins in pear (Pyrus bretchneideri)

Keywords: oligonucleotide antisense; CrRLK1L; Catharanthus roseus RLK1-like kinases; RLKs; receptor-like kinases; PERKs; proline-rich extensin-like receptor-kinases; CRKs; cysteine-rich; LRR-RLKs; leucine-rich repeat RLKs; HERK1; HERCULES Receptor Kinase 1; RALFs; rapid alkalinization factor

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Small Nucleolar Noncoding RNA SNORA23, Up-Regulated in Human Pancreatic Ductal Adenocarcinoma, Regulates Expression of Spectrin Repeat-Containing Nuclear Envelope 2 to Promote Growth and Metastasis of Xenograft Tumors in Mice

Keywords: oligonucleotide antisense; Pancreatic Cancer; Liver Metastasis; Oncogene; Non-Coding RNA; AmNA; amido-bridged nucleic acids; ASO; antisense oligonucleotide; cDNA; complementary DNA; CEA; carcinoembryonic antigen; HLMC; highly liver metastatic cell; IPMN; intraductal papillary mucin

دانلود رایگان متن کامل مقاله ISI 71 صفحه سال انتشار : 2017 سفارش ترجمه

Contributions of Japanese patients to development of antisense therapy for DMD

Keywords: oligonucleotide antisense; Duchenne muscular dystrophy; Becker muscular dystrophy; Exon skipping; Antisense oligonucleotide; Reading frame; Treatment

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Pathological microRNAs in acute cardiovascular diseases and microRNA therapeutics

Keywords: oligonucleotide antisense; Non-protein coding RNAs; Antisense oligonucleotide; Hypertension

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis of novel caged antisense oligonucleotides with fluorescence property

Keywords: oligonucleotide antisense; Caged compound; Thiochromone; Antisense oligonucleotide; Fluorescence; Luciferin-luciferase reaction;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleIn vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides

Keywords: oligonucleotide antisense; HBV; hepatitis B virus; ASO; antisense oligonucleotide; HBsAg; hepatitis B surface antigen; HCC; hepatocellular carcinoma; NTCP; sodium taurocholate cotransporting polypeptide; cccDNA; circular covalently closed DNA; RT; reverse transcriptase; HBcAg; hepa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Increase of neurofilament-H protein in sensory neurons in antiretroviral neuropathy: Evidence for a neuroprotective response mediated by the RNA-binding protein HuD

Keywords: oligonucleotide antisense; aODN; antisense oligonucleotide; BDNF; brain derived neurotrophic factor; ddC; 2⿲,3⿲-dideoxycitidine; DMSO; dimethylsulfoxide; DRG; dorsal root ganglia; i.p.; intraperitoneal; i.t.; intrathecal; LFB; luxol fast blue; NF-L; neurofilament light; NF-M; n

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Integrated analysis of the prostate cancer small-nucleolar transcriptome reveals SNORA55 as a driver of prostate cancer progression

Keywords: oligonucleotide antisense; Prostate cancer; SNORA55; Non-coding RNAs; Patient-derived xenograft; Next generation sequencing; Antisense oligonucleotide;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Osmolality of antisense oligonucleotide parenteral formulations: Implications on counterion dissociation and recommended osmometry techniques

Keywords: oligonucleotide antisense; Osmolality; Osmometry; Counterion dissociation; Antisense oligonucleotide;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Oral delivery of macromolecular drugs: Where we are after almost 100 years of attempts

Keywords: oligonucleotide antisense; ADH; anti-diuretic hormone; AON; antisense oligonucleotide; 5-CNAC; N-(5-chlorosalicyloyl)-8-aminocaprylic acid; EDTA; ethylenediaminetetraacetate; FDA; Food and Drug Administration; GC C; guanylyl cyclase C; GI; gastrointestinal; GLP-1; glucagon-like pep

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Evaluation of the effects of chemically different linkers on hepatic accumulations, cell tropism and gene silencing ability of cholesterol-conjugated antisense oligonucleotides

Keywords: oligonucleotide antisense; Cholesterol conjugation; Linkage; Antisense oligonucleotide;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Survivin-targeted nanoparticles for pancreatic tumor imaging in mouse model

Keywords: oligonucleotide antisense; Survivin; Antisense oligonucleotide; Magnetic nanoparticles; Pancreatic cancer; Magnetic resonance imaging;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Targeting PCSK9 as a promising new mechanism for lowering low-density lipoprotein cholesterol

Keywords: oligonucleotide antisense; ALT; alanine transaminase; ASO; antisense oligonucleotide; apoB; apolipoprotein B; CVD; cardiovascular disease; EGF; epidermal growth factor; LDL-C; low-density lipoprotein cholesterol; MTP; microsomal triglyceride transfer protein; PCSK9; proprotein conv

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2016 سفارش ترجمه

XRN2 is required for the degradation of target RNAs by RNase H1-dependent antisense oligonucleotides

Keywords: oligonucleotide antisense; Antisense oligonucleotide; RNase H1; Exoribonuclease; RNA degradation; siRNA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه