Keywords: Malaria; Plasmodium falciparum; Drug targets; Apicoplast; Cytoplasm; Mitochondria;
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Keywords: RBC; red blood cell; TEM; transmission electron microscopy; IMC; inner membrane complex; PV; parasitophorous vacuole; RT; room temperature; ER; endoplasmic reticulum; Apical complex; Apicoplast; Babesia divergens; Free merozoite; Inner membrane complex; U
Keywords: Apicoplast; Antibiotics; Drug-target; Endosymbiosis; Malaria; Plasmodium falciparum
Keywords: Apicoplast; Chloroplast; Plastid; Apicomplexa; Transcription; Post-transcriptional processing;
Keywords: Apicoplast; DNA replication; Malaria; Drug discovery;
Keywords: Apicoplast; Phylogeny; Evolution; Plasmodium;
Keywords: Malaria; Apicoplast; Cytochrome P450; Clarithromycin; Mefloquine
Keywords: Malaria; plDNA; Gyrase; Topoisomerase; Apicoplast; Fluoroquinolone
Keywords: ACC; acetyl-coenzyme A carboxylase; ACP; acyl carrier protein; ACPS; acyl carrier protein synthase; ACS; acyl-coenzyme A synthetase; CoA; coenzyme A; DHAP; dihydroxyacetone phosphate; dim; cyclohexanedione; DOXP pathway; 1-deoxy-d-xylulose-5-phosphate/non
Keywords: Apicoplast; loop-mediated isothermal amplification; malaria; molecular diagnosis; polymerase chain reaction;
Keywords: Toxoplasma gondii; Apicoplast; Quinoline derivatives
Antiprotozoal treatment of canine babesiosis
Keywords: Imidocarb dipropionate; Diminazene aceturate; Atovaquone; Buparvaquone; Azithromycin; Apicoplast;
Molecular evolution and functional divergence of IspD homologs in malarial parasites
Keywords: IspD; Evolutionary imprints; Non-mevalonate pathway; Divergence; Apicoplast; Antimalarial drugs; Molecular evolution;
Deciphering the role of IspD (2âCâmethylâDâerythritol 4âphosphate cytidyltransferase) enzyme as a potential therapeutic drug target against Plasmodium vivax
Keywords: IspD; (2âCâmethylâd-erythritol 4-phosphate cytidyltransferase); PvIspD; Plasmodium vivax IspD; PfIspD; Plasmodium falciparum IspD; AtIspD; Arabidopsis thaliana IspD; MEP; Methyl erythritol phosphate (Non-mevalonate); HTS; High Throughput Screening;
Invited ReviewThe apicoplast: now you see it, now you don't
Keywords: Apicoplast; Endosymbiosis; Malaria; Plasmodium; Plastid; Toxoplasma;
Characterization of 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (IspG) from Plasmodium vivax and it's potential as an antimalarial drug target
Keywords: Apicoplast; MEP isoprenoids biosynthesis pathway; GcpE/IspG;
Determination of glutathione redox potential and pH value in subcellular compartments of malaria parasites
Keywords: ART; artemisinin; CLSM; confocal laser scanning microscopy; CQ; chloroquine; CS; citrate synthase; DIA; diamide; DTT; 1,4-dithiothreitol; FSM; fosmidomycin; GFP; green fluorescent protein; hGrx1; human glutaredoxin 1; GSH; reduced glutathione; GSSG; gluta
Structural and functional characterization of an iron-sulfur cluster assembly scaffold protein-SufA from Plasmodium vivax
Keywords: Fe-S; iron-sulfur; Suf; sulfur mobilization; Pv; Plasmodium vivax; EPR; electro paramagnetic resonance; Isc; iron-sulfur cluster; Nif; nitrogen fixation; Apicoplast; Suf pathway; Clinical isolates; Immunofluorescence;
Transcripts in the Plasmodium Apicoplast Undergo Cleavage at tRNAs and Editing, and Include Antisense Sequences
Keywords: Apicoplast; chloroplast; RNA processing; Plasmodium; antisense RNA; RNA editing.;
Identification of Toxoplasma TgPH1, a pleckstrin homology domain-containing protein that binds to the phosphoinositide PI(3,5)P2
Keywords: Toxoplasma gondii; Apicoplast; Phosphoinositides; Pleckstrin Homology domain; PI(3,5)P2;
Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure–activity studies
Keywords: Malaria; Plasmodium; Apicoplast; MEP pathway; Non-mevalonate
Two recently sequenced vertebrate genomes are contaminated with apicomplexan species of the Sarcocystidae family
Keywords: Apicomplexa; Apicoplast; Sarcocystis; Apicortin; Host; Phylogenetic tree; Bat; Nephroisospora;
Apicoplast acetyl Co-A carboxylase of the human malaria parasite is not targeted by cyclohexanedione herbicides
Keywords: Acetyl Co-A carboxylase; Apicoplast; Fatty acid biosynthesis; Herbicides; Malaria;
Plastids with or without galactoglycerolipids
Keywords: galactoglycerolipids; plastid; apicoplast; secondary endosymbiosis; Chromera; Plasmodium
Biochemical characterization of the apicoplast-targeted AAA+ ATPase ClpB from Plasmodium falciparum
Keywords: IPTG; isopropyl β-d-1-thiogalactopyranoside; ATPγS; adenosine-5â²-(γ-thio)-triphosphate; Molecular chaperone; Protein aggregation; ClpB; Malaria; Plasmodium falciparum; Apicoplast;
ApicoAMP: The first computational model for identifying apicoplast-targeted transmembrane proteins in Apicomplexa
Keywords: Apicoplast; Apicoplast-targeted membrane proteins; Transmembrane proteins; Apicomplexa; Machine learning; Ensemble classification models
AUTOPHAGY IN PLASMODIUM, A MULTIFUNCTIONAL PATHWAY?
Keywords: Plasmodium; apicoplast; heme; Atg; digestive vacuole
Insight into structural and biochemical determinants of substrate specificity of PFI1625c: Correlation analysis of protein-peptide molecular models
Keywords: Malaria; Drugs; Resistance; Modeling; Peptides; Protein sorting; Metalloprotease; Mitochondria; Apicoplast
The effect of fusidic acid on Plasmodium falciparum elongation factor G (EF-G)
Keywords: Plasmodium falciparum; Fusidic acid; Thiostrepton; Elongation factor-G; Apicoplast; Mitochondria
Babesia bovis: A bipartite signal directs the glutamyl-tRNA synthetase to the apicoplast
Keywords: Babesia bovis; Apicoplast; Traffic; Glutamyl tRNA synthetase; Transfection;
Characterization of acyl carrier protein and LytB in Babesia bovis apicoplast
Keywords: Apicomplexan; Apicoplast; Babesia bovis; Plasmodium falciparum; FASII; MEP; ACP; LytB;
Dual targeting of aminoacyl-tRNA synthetases to the apicoplast and cytosol in Plasmodium falciparum
Keywords: Plasmodium; Malaria; Apicoplast; tRNA synthetase; Aminoacyl-tRNA synthetase; Dual targeting; Borrelidin; Mupirocin;
Plasmodium vivax apicoplast genome: A comparative analysis of major genes from Indian field isolates
Keywords: Plasmodium vivax; Apicoplast; Plastid DNA; Codon usage; Phylogeny;
Wherever I may roam: Protein and membrane trafficking in P. falciparum-infected red blood cells
Keywords: Malaria; Plasmodium; Protein trafficking; PEXEL; Apicoplast; Erythrocyte
The primase domain of PfPrex is a proteolytically matured, essential enzyme of the apicoplast
Keywords: ZBD, zinc-binding domain; TOPRIM, topoisomerase-primase; PAR, 4-(2-pyridylazo)resorcinolPlasmodium falciparum; Malaria; Apicoplast; DNA replication; Primase; Proteolytic processing
Interaction between sulphur mobilisation proteins SufB and SufC: Evidence for an iron–sulphur cluster biogenesis pathway in the apicoplast of Plasmodium falciparum
Keywords: [Fe–S] cluster; Apicoplast; Plasmodium falciparum; Suf pathway; SufB; SufC
Interaction of apicoplast-encoded elongation factor (EF) EF-Tu with nuclear-encoded EF-Ts mediates translation in the Plasmodiumfalciparum plastid
Keywords: Plasmodium falciparum; Apicoplast; Translation; EF-Tu; EF-Ts; Kirromycin;
The search for the missing link: A relic plastid in Perkinsus?
Keywords: Apicoplast; Chromalveolata hypothesis; Genome; Perkinsus; Plastid; Protozoan; Targeting
Selective accumulation of a novel antimalarial rhodacyanine derivative, SSJ-127, in an organelle of Plasmodium berghei
Keywords: SSJ-127; Plasmodium berghei; Antimalarial rhodacyanine; Apicoplast; Mitochondrion
The carbon and energy sources of the non-photosynthetic plastid in the malaria parasite
Keywords: Plastid; Apicoplast; Malaria; Carbon; Energy; Plasmodium;
Diversity and similarity in the tRNA world: Overall view and case study on malaria-related tRNAs
Keywords: tRNA structure; Mitochondria; Apicoplast; Anopheles gambiae; Plasmodium falciparum; Homo sapiens
Apicoplast: keep it or leave it
Keywords: Apicomplexa; Apicoplast; Metabolism; Isoprenoid; Fatty acids; Iron–sulfur cluster; Haem; Lipoic acidFASII, Fatty-acid type II; IPP, Isopentenyl-pyrophosphate; [FE–S], Iron–sulfur; PDH, Pyruvate–dehydrogenase complex; DOXP, 1-Deoxy-d-xylulose 5-phosphate;
Role of chloroplasts and other plastids in ageing and death of plants and animals: A tale of Vishnu and Shiva
Keywords: Ageing; Algae; Apicoplast; Bleaching; Chloroplast; Coral reef; Death; Degeneration; Endosymbiosis; Giant clam; Kleptoplast; Malaria; Monocarpic; Photosynthesis; Plants; Plasmodium; Plastid; Polycarpic; Sea slug; Survival; Symbiosis; Toxoplasma; Vacuole
More Membranes, more Proteins: Complex Protein Import Mechanisms into Secondary Plastids
Keywords: Apicoplast; chloroplast; Apicomplexa; protein import; targeting.
The Clp Chaperones and Proteases of the Human Malaria Parasite Plasmodium falciparum
Keywords: RBC, red blood cell; SEC, size-exclusion chromatography; STEM, scanning transmission electron microscopePlasmodium falciparum; apicoplast; PfClp ATPases; PfClp proteases; protein homeostasisABC, ATP-binding cassette; hmu, heme uptake system; DMSO, dimethy
Toxoplasma gondii: A simple Real-time PCR assay to quantify the proliferation of the apicoplast
Keywords: Toxoplasma gondii; Apicoplast; Real-time PCR; Ciprofloxacin; Clindamycin; Azithromycin
Short communicationMitochondrial localization of functional ferrochelatase from Plasmodium falciparum
Keywords: Ferrochelatase; Heme; Mitochondrion; Apicoplast; Plasmodium falciparum;
Pyruvate kinase type-II isozyme in Plasmodium falciparum localizes to the apicoplast
Keywords: Plasmodium falciparum; Pyruvate kinase II; Apicoplast; Mitochondria; Cell-free expression
Thiolactomycin analogues as potential anti-Toxoplasma gondii agents
Keywords: Apicomplexa; Apicoplast; Thiolactomycin; Fatty acid biosynthesis;
Plasmodium falciparum: Organelle-specific acquisition of lipoic acid
Keywords: ACP; acyl carrier protein; DHLA; dihydrolipoic acid; GCS; glycine cleavage system; KADH; α-keto acid dehdyrogenase complex; LA; lipoic acid; PDH; pyruvate dehydrogenase; PVM; parasitophorous vacuolar membrane; Malaria; Drug target; Apicoplast; Mitochondr