Keywords: Bile acids; Liver; Intestine; Transporters; Lipid metabolism; Energy homeostasisACCII, acetyl-CoA carboxylase 2; APO, apolipoproteins; ASBT, apical sodium-dependent bile acid transporter; BSEP, bile salt export pump; CYP7A1, cholesterol 7α-hydroxylase; DI
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The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator
Keywords: PFIC1, progressive familial intrahepatic cholestasis type 1; CFTR, cystic fibrosis transmembrane conductance regulator; CF, cystic fibrosis; Isc, short circuit current; TGN, trans-Golgi network; ASBT, apical sodium-dependent bile acid transporter; AP, alk
Inflammatory-mediated repression of the rat ileal sodium-dependent bile acid transporter by c-fos nuclear translocation
Keywords: ABP, apical sodium-dependent bile acid transporter binding protein; AP-1, activated protein-1; ASBT, apical sodium-dependent bile acid transporter; bp, base pair; dAP-1, downstream activator protein-1; IEC-6, intestinal epithelial cell-6; IL, interleukin;
Transport and biological activities of bile acids
Keywords: ABCB11, bile salt export pump; ASBT, apical sodium-dependent bile acid transporter; EHC, enterohepatic circulation; FABP1, liver-type fatty acid binding protein; FXRα, farnesoid-x-receptor α; ILBP, ileal lipid binding protein; NTCP, sodium/taurocholate co
PXR Prevents Cholesterol Gallstone Disease by Regulating Biosynthesis and Transport of Bile Salts
Keywords: Fgf15; PCN; Nuclear Receptor; Gene Regulation; Transgenic MiceAbc, ATP binding cassette; Asbt, apical sodium-dependent bile acid transporter; Bsep, bile salt export pump; CAR, constitutive androstane receptor; CGD, cholesterol gallstone disease; CSI, chol
Impact of carriers in oral absorption: Permeation across Caco-2 cells for the organic anions estrone-3-sulfate and glipizide
Keywords: OATP, organic anion transporting polypeptide; ASBT, apical sodium-dependent bile acid transporter; SOAT, sodium-dependent organic anion transporter; MCT, monocarboxylate transporter; BCRP, breast cancer resistant protein; MRP, multidrug-resistant related
Transactivation of the human apical sodium-dependent bile acid transporter gene by human serum
Keywords: ASBT, apical sodium-dependent bile acid transporter; PCR, polymerase chain reaction; FXR, farnesoid X receptor; SHP, small heterodimer partner; LRH, liver receptor homologue; RAR/RXR, retinoic acid receptor/retinoid X receptor; HNF, hepatocyte nuclear fac
Effects of bile acids on expression of the human apical sodium dependent bile acid transporter gene
Keywords: ASBT, Apical sodium-dependent bile acid transporter; PCR, Polymerase chain reaction; FXR, Farnesoid X receptor; RAR/RXR, Retinoic acid receptor/retinoid X receptor; AP-1, Activated protein-1; PPAR, Peroxisome proliferation-activated; UTR, Untranslated reg
Novel bile acid derivatives (BANBs) with cytostatic activity obtained by conjugation of their side chain with nitrogenated bases
Keywords: ASBT, apical sodium-dependent bile acid transporter; BA, bile acid; BANB, bile acid-nitrogenated base conjugate; CA, cholic acid; FAB, fast atom bombardment; GCA, glycocholic acid; HRMS, high-resolution mass spectrometry; MDR, multidrug resistance protein