Keywords: آرونوفین; Alphavirus; Chikungunya virus; Protein folding; Protein disulfide isomerase; Thioredoxin reductase; Auranofin;
مقالات ISI آرونوفین (ترجمه نشده)
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Keywords: آرونوفین; Auranofin; Thioredoxin reductase; Glutathione peroxidase; Reactive oxygen species; Oxidative stress; Selenium;
Keywords: آرونوفین; Membrane fluidity; Auranofin; Drug sensitivity; Ovarian cancer; DNA damage; Cell survival;
Keywords: آرونوفین; Repurposing; Auranofin; Multidrug resistance; Topical antimicrobials; Inflammatory cytokines
Keywords: آرونوفین; ANF; auranofin; cDDP; cisplatin (cis-diamminedichloroplatinum(II)); Cys; cysteine; DMSO; dimethylsulfoxide; DMEM; Dulbecco's Modified Eagle's Medium; Dp44mT; 2,2â²-Dipyridyl-N,N-dimethylsemicarbazone; FBS; fetal bovine serum; Fe; iron; GPx; glutathio
Keywords: آرونوفین; Oxidative stress; Reproductive toxicity; Auranofin; Zebrafish; Longitudinal cohort
Keywords: آرونوفین; 2DG; 2-deoxy-d-glucose; NAC; N-acetylcysteine; GSH; glutathione; GSSG; glutathione disulfide; DHEA; dehydroepiandrosterone; Au; auranofin; G6PDH; glucose-6-dehydrogenase; ROS; reactive oxygen species; Trx; thioredoxin; TrxR; thioredoxin reductase; Dehydro
Biochemical and thermodynamic comparison of the selenocysteine containing and non-containing thioredoxin glutathione reductase of Fasciola gigantica
Keywords: آرونوفین; Platyhelminthes; Parasite; Liver fluke; Thioredoxin glutathione reductase; Glutathione reductase; Thioredoxin reductase; Glutathione; Activity; Homology modeling; Auranofin; Inhibition;
Time- and cell-resolved dynamics of redox-sensitive Nrf2, HIF and NF-κB activities in 3D spheroids enriched for cancer stem cells
Keywords: آرونوفین; AUR; auranofin; CA9; carbonic anhydrase IX; CDKN1B; cyclin-dependent kinase inhibitor 1B (p27); CSC; cancer stem cell; DMOG; dimethyloxalylglycine; GSH; glutathione; HIF; hypoxia inducible factor; MUC2; mucin2; NCL; nucleolin; NFE2L2 or Nrf2; nuclear fact
Differential redox sensitivity of cathepsin B and L holds the key to autophagy-apoptosis interplay after Thioredoxin reductase inhibition in nutritionally stressed SH-SY5Y cells
Keywords: آرونوفین; AMS; 4-Acetamido-4â²-Maleimidylstilbene-2,2â²-Disulfonic Acid; Au; auranofin; CA-074-me; CA-074 methyl ester; CCK-8; cell counting kit-8; CTSB; Cathepsin B; CTSL; Cathepsin L; CysC; Cystatin C; DMEM; Dulbecco's modified eagle medium; DTT; dithiothreitol
Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo
Keywords: آرونوفین; Protozoa; Parasite; Antimicrobial therapy; Drug development; Gold compounds; Auranofin;
BRCA1 deficiency increases the sensitivity of ovarian cancer cells to auranofin
Keywords: آرونوفین; Auranofin; BRCA1; Nrf2; DNA damage; Ovarian cancer
Spectroscopic investigation of auranofin binding to zinc finger HIV-2 nucleocapsid peptides
Keywords: آرونوفین; Auranofin; 1-Thio-β-d-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate; TCEP; Tris(2-carboxyethyl)phosphine hydrochloride; PAR; 4-(pyridyl-2-azo)-resorcinol; Auranofin; Zinc finger; HIV-2; Mass spectrometry; CD; Fluorescence;
X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action
Keywords: آرونوفین; Trx; thioredoxin; TrxR; thioredoxin reductase; TGR; thioredoxin-glutathione reductase; DTNB; 5,5â²-dithiobis(2-nitrobenzoic acid); TNB; thionitrobenzoate; Human amebiasis; Entamoeba histolytica; Auranofin; Thioredoxin reductase; Thioredoxin; X-ray struct
Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells
Keywords: آرونوفین; 3-MA; 3-Methyl adenine; AL; autolysosome; AP; autophagosome; ATG; autophagy related; Au; auranofin; Baf A1; bafilomycin A1; CCK-8; cell counting kit-8; CQ; chloroquine; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulfoxide; DTNB; 5,5'-Dithi
In vivo and in vitro auranofin activity against Trypanosoma cruzi: Possible new uses for an old drug
Keywords: آرونوفین; Trypanosoma cruzi; Chemotherapy; Auranofin;
Reactions of model proteins with aurothiomalate, a clinically established gold(I) drug: The comparison with auranofin
Keywords: آرونوفین; Aurothiomalate; Auranofin; Proteins; Mass spectrometry
Auranofin-induced oxidative stress causes redistribution of the glutathione pool in Taenia crassiceps cysticerci
Keywords: آرونوفین; AF; auranofin; BSO; buthionine sulfoximine; GR; glutathione reductase; GSH; reduced-form glutathione; GSSG; glutathione disulfide; NAC; N-acetyl cysteine; PSSG; protein-complexed glutathione; ROS; reactive oxygen species; TGR; thioredoxin-glutathione redu
Evidence that the antiproliferative effects of auranofin in Saccharomyces cerevisiae arise from inhibition of mitochondrial respiration
Keywords: آرونوفین; Auranofin; Yeast; Respiration inhibition; Antiproliferation; Pos5 NADH kinase
Auranofin and related heterometallic gold(I)-thiolates as potent inhibitors of methicillin-resistant Staphylococcus aureus bacterial strains
Keywords: آرونوفین; Antimicrobial; Auranofin; Heterometallic gold-thiolates; MRSA;
Effects of mitochondrial poisons on the neuropathic pain produced by the chemotherapeutic agents, paclitaxel and oxaliplatin
Keywords: آرونوفین; Allodynia; Auranofin; Hyperalgesia; Neuropathic pain; Oligomycin; Rotenone;
Investigation of a potential mechanism for the inhibition of SmTGR by Auranofin and its implications for Plasmodium falciparum inhibition
Keywords: آرونوفین; S. mansoni; P. falciparum; Thioredoxin Glutathione Reductase; Auranofin
On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases
Keywords: آرونوفین; Thioredoxin Glutathione Reductase; Gold–cysteine complex; Gold–selenocysteine complex; Auranofin
Gold-phosphine binding to de novo designed coiled coil peptides
Keywords: آرونوفین; De novo peptide; Coiled coil; Protein design; Gold phosphine; Auranofin
The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity
Keywords: آرونوفین; Multiple myeloma; Auranofin; Apoptosis; Mcl-1; NF-κB; IL-6; JAK/STAT
A study of the relative importance of the peroxiredoxin-, catalase-, and glutathione-dependent systems in neural peroxide metabolism
Keywords: آرونوفین; AF; auranofin; AT; aminotriazole; CuOOH; cumene hydroperoxide; BCNU; 1,3-bis(2-chloroethyl)-1-nitrosourea; CAT; catalase; Chaps; 3-((3-cholamidopropyl)dimethylammonio)-1-propane sulfonate hydrate; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl s
Mitochondrial respiratory chain involvement in peroxiredoxin 3 oxidation by phenethyl isothiocyanate and auranofin
Keywords: آرونوفین; AFN; auranofin; NEM; N-ethylmaleimide; PEITC; phenethyl isothiocyanate; Prx; peroxiredoxin; Ï0; mitochondrial DNA deplete; TrxR; thioredoxin reductase; Hydrogen peroxide; Redox signaling; Oxidative stress; Thioredoxin reductase; Thioredoxin; Mitochondria
Structural analysis of the anti-arthritic drug Auranofin: Its complexes with cysteine, selenocysteine and their fragmentation products
Keywords: آرونوفین; Auranofin; Cysteine; Selenocysteine; Gold; DFT; Mass spectrometry; Collision-induced dissociation
A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: Implications for anticancer therapeutics targeted to mitochondria
Keywords: آرونوفین; ÎÏm; mitochondrial membrane potential; DLC; delocalized lipophilic cation; MPT; membrane permeability transition; Auranofin; 2,3,4,6-tetra-O-acetyl-l-thio-β-d-glucopyranosato-S-triethylphosphine gold(I); TrxR; thioredoxin reductase; Trx; thioredoxin; [
Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4
Keywords: آرونوفین; Auranofin; Gold; Toll-like receptor; LPS; Dimerization; NF-κB; COX-2; MyD88; TRIF; IKKβ
Synthesis and structural characterisation of linear Au(I) N-heterocyclic carbene complexes: New analogues of the Au(I) phosphine drug Auranofin
Keywords: آرونوفین; N-heterocyclic carbene complexes; Gold complexes; Auranofin
The modulation of thiol redox state affects the production and metabolism of hydrogen peroxide by heart mitochondria
Keywords: آرونوفین; Arsenite; Auranofin; BCNU; Diamide; Glutathione; Hydrogen peroxide; Mitochondria; Selenium; Thioredoxin reductase; Thiol redox state;