Keywords: آگونیسم انگیخته; G protein-coupled receptor; Calcitonin receptor; GPCR structure-function; Biased agonism; Molecular modelling;
مقالات ISI آگونیسم انگیخته (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: آگونیسم انگیخته; cAMP; 3â²,5â²-cyclic adenosine monophosphate; CHO; Chinese hamster ovary; DMEM; Dulbecco's modified Eagle medium; FBS; fetal bovine serum; GLP-1; glucagon-like peptide-1; GPCR; G protein-coupled receptor; iCa2+; intracellular calcium; pERK; extracellu
Keywords: آگونیسم انگیخته; Biased agonism; Positive allosteric modulator; Stimulus bias; Metabotropic glutamate receptor 5; Glutamate (L-glutamic acid PubChem CID: 33032); DHPG (PubChem CID: 108001); VU0424465 (PubChem CID: 53384864); VU0403602 (PubChem CID: 53384878); VU29 (PubChe
Keywords: آگونیسم انگیخته; G protein coupled receptors; Endothelin; ETA; ETB; Biased agonism; Biased antagonism; β-Arrestin; Bosentan; Pathway selectivity; IRL1620;
Keywords: آگونیسم انگیخته; Neurotensin receptor-1; Pathway; Label-free cell phenotypic profiling; Biased agonism
Keywords: آگونیسم انگیخته; Seven transmembrane-spanning receptor (7TMR); Two-site model; Chemokine stoichiometry; 7TMR activation; Biased agonism;
Keywords: آگونیسم انگیخته; ASM; airway smooth muscle; AHR; airway hyperresponsiveness; β2AR; beta 2 adrenergic receptor; BTR; bitter taste receptor; CysLT1R; cysteinyl leukotriene receptor 1; CaSR; calcium sensing receptor; EP; prostanoid EP receptor; GPCR; G protein-coupled recep
Keywords: آگونیسم انگیخته; Biased agonism; Opioid receptor; Kappa opioid receptor; Dynorphin; Mood disorders;
Keywords: آگونیسم انگیخته; biased signaling; biased agonism; receptor theory
Keywords: آگونیسم انگیخته; G protein-coupled receptors; partial agonism; biased agonism; rational ligand design; dynamic ligand binding; dualsteric binding
Keywords: آگونیسم انگیخته; AC; adenylate cyclase; β-AR; β-adrenergic receptor; CaM; calmoduline; cAMP; cyclic adenosine monophosphate; CHO; Chinese hamster ovary; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; DAG; diacylglycerol; DR; dopamine
Keywords: آگونیسم انگیخته; somatostatin analogs; antitumor efficacy; pharmacotherapy; biased agonism; neuroendocrine tumors
Understanding the mechanism of bias signaling of the insulin-like growth factor 1 receptor: Effects of LL37 and HASF
Keywords: آگونیسم انگیخته; HASF; hypoxia and Akt induced stem cell factor; Biased agonism; LL37; HASF; Extracellular-signal-regulated kinase (ERK); Insulin-like growth factor (IGF); IGF1R;
Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics
Keywords: آگونیسم انگیخته; 7TMR; GPCR; Arrestin; β-Arrestin; Biased agonism; Biased agonist; Mass spectrometry; Proteomics; Pharmacology; Drug discovery;
New insights about the peculiar role of the 28-38 C-terminal segment and some selected residues in PACAP for signaling and neuroprotection
Keywords: آگونیسم انگیخته; ACN; acetonitrile; BBB; bloodbrain barrier; Bip; biphenylalanine; Boc; tert-butoxycarbonyl; BOP; (benzotriazol-1-yloxy)tris(dimethylamino) phosphonium hexafluorophosphate; BRET; bioluminescence resonance energy transfer; CHO cells; Chinese hamster ovary c
Glucagon-like peptide-1 receptor internalisation controls spatiotemporal signalling mediated by biased agonists
Keywords: آگونیسم انگیخته; Glucagon-like peptide 1 receptor; Biased agonism; Receptor trafficking; Internalisation; Spatiotemporal signalling;
Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1
Keywords: آگونیسم انگیخته; Glucagon-like peptide-1 receptor; G protein coupled receptor; Biased agonism; Cell signaling; Peptides;
Noradrenaline, oxymetazoline and phorbol myristate acetate induce distinct functional actions and phosphorylation patterns of α1A-adrenergic receptors
Keywords: آگونیسم انگیخته; ARs; adrenergic receptors; PKC; protein kinase C; NA; noradrenaline; OXY; oxymetazoline; PMA; phorbol 12-myristate 13-acetate; eGFP; enhanced green fluorescent protein; PBS; phosphate-buffered saline; GRKs; G protein-coupled receptors kinases; IL3; intrac
Diverse arrestin-recruiting and endocytic profiles of tricyclic antipsychotics acting as direct α2A adrenergic receptor ligands
Keywords: آگونیسم انگیخته; Antipsychotic; Endocytosis; Arrestin; Biased agonism; α2 adrenergic receptor; Lipid raft;
Clozapine as the most efficacious antipsychotic for activating ERK 1/2 kinases: Role of 5-HT2A receptor agonism
Keywords: آگونیسم انگیخته; Antipsychotics; Clozapine; ERK1/2; AKT; 5-HT2A; Biased agonism;
Molecular insights into allosteric modulation of Class C G protein-coupled receptors
Keywords: آگونیسم انگیخته; GABAB; γ-aminobutyric acid receptor B; BMD; bone mass and density; CaSR; calcium-sensing receptor; CHO; Chinese hamster ovary; CRD; cysteine-rich domain; ER; endoplasmic reticulum; Ca2+o; extracellular calcium; pERK1/2; extracellular signal-regulated kin
GPR40 agonists for the treatment of type 2 diabetes mellitus: The biological characteristics and the chemical space
Keywords: آگونیسم انگیخته; GPR40; G protein-coupled receptor 40; FFA1; free fatty acid receptor 1; PK; pharmacokinetic; GSIS; glucose-stimulated insulin secretion; T2DM; type 2 diabetes mellitus; IDF; International Diabetes Federation; GLP-1; glucagon-like peptide1; GIP; gastric in
Biased signalling is an essential feature of TLR4 in glioma cells
Keywords: آگونیسم انگیخته; TLR4; LPS; NF-kappaB; IRF3; Inflammatory balance; Biased agonism;
Cardiac action of the first G protein biased small molecule apelin agonist
Keywords: آگونیسم انگیخته; Apelin; Biased agonism; G protein coupled receptor; Cardiovascular; In vivo;
Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptor
Keywords: آگونیسم انگیخته; AC; adenylyl cyclase; α-neo; α-neoendorphin; β-arr1 and β-arr2; β-arrestin 1 and 2; BRET; bioluminescence resonance energy transfer; CHO; Chinese hamster ovary; DAMGO; d-Ala2-N-MePhe4-Gly-ol enkephalin; endo; endomorphin; pERK; extracellular signal r
Short CommunicationDelta opioid receptors expressed in forebrain GABAergic neurons are responsible for SNC80-induced seizures
Keywords: آگونیسم انگیخته; DOR; delta opioid receptor; EEG; electroencephalogram; Delta opioid receptor; Conditional knockout; Epileptic seizure; Delta agonist; Biased agonism; In vivo;
Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism
Keywords: آگونیسم انگیخته; Metabotropic glutamate receptor 1; Biased agonism; Glutamate; Quisqualate; DHPG; Cerebellar granule cells; ACPD; 1-Aminocyclopentane-1,3-dicarboxylic acid; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium; DHPG; 3,5-dihydroxyphenylglycine; CPCCOE
Emerging Functional Divergence of β-Arrestin Isoforms in GPCR Function
Keywords: آگونیسم انگیخته; G protein-coupled receptors; arrestin; cellular signaling; biased agonism; desensitization; mitogen-activated protein kinase.
The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?
Keywords: آگونیسم انگیخته; GPR40/FFA1; type 2 diabetes; pancreatic β cell; insulin secretion; biased agonism
Biased agonism of the calcium-sensing receptor
Keywords: آگونیسم انگیخته; Calcium-sensing receptor; Biased agonism; G protein-coupled receptor; Inositol phosphate; Cyclic AMP; ERK
Alternative G protein coupling and biased agonism: New insights into melanocortin-4 receptor signalling
Keywords: آگونیسم انگیخته; ACTH; adrenocorticotropic hormone; cAMP; cyclic 3â²,5â²-adenosine monophosphate; AGRP; agouti-related protein; CTX; cholera toxin; ER; endoplasmic reticulum; ERK-1/2; extracellular signal-regulated kinases; FSK; forskolin; GPCR; G protein-coupled recept
Selective agonism in somatostatin receptor signaling and regulation
Keywords: آگونیسم انگیخته; Somatostatin receptors; Receptor signaling; Receptor internalization; Receptor desensitization; Somatostatin analogs; Biased agonism; Stimulus trafficking