Keywords: EPO, eosinophil peroxidase; ECP, eosinophil cationic protein; MBP, major basic protein; EDN, eosinophil-derived neurotoxin; TM, thrombomodulin; BSA, bovine serum albumin; BMMCs, bone marrow-derived mast cells; TNP, trinitrophenyl; OVA, ovalbumin; IL, inte
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IL-33 promotes ICAM-1 expression via NF-kB in murine mast cells
Keywords: Ag, Antigen; APC, Allophycocyanin; BMMCs, Bone marrow-derived mast cells; β-hex, β-hexosaminidase; FITC, fluorescein isothiocyanate; ICAM-1, Intercellular adhesion molecule-1; MCs, Mast cells; PBS, Phosphate buffered saline; PE, R-Phycoerythrin; 7-AAD, 7-
15,16-Dihydrotanshinone I suppresses IgE-Ag stimulated mouse bone marrow-derived mast cell activation by inhibiting Syk kinase
Keywords: AA, arachidonic acid; BMMCs, bone marrow-derived mast cells; COX-1,-2, cyclooxygenase-1, -2; cPLA2, cytosolic phospholipase A2; DMSO, dimethyl sulfoxide; DNP, dinitrophenol; DTT, dithiothreitol; EIA, enzyme immunoassay; ERK1/2, extracellular signal regula
5-Lipoxygenase inhibitors suppress RANKL-induced osteoclast formation via NFATc1 expression
Keywords: 5-LO, 5-lipoxygenase; LTs, leukotrienes; BMMs, bone marrow-derived macrophages; BMMCs, bone marrow-derived mast cells; LPS, lipopolysaccharide; M-CSF, macrophage-colony stimulating factor; RANK, a receptor of RANKL; RANKL, receptor activator of nuclear fa
A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses
Keywords: Ag, antigen; BMMCs, bone marrow-derived mast cells; FcεRI, high affinity IgE receptor; hu, human; MC, mast cell; m, mouse; SCF, stem cell factorDegranulation; FcεRI; KIT; Mast cells; KIT; SCF
IgE production in CD40/CD40L cross-talk of B and mast cells and mediator release via TGase 2 in mouse allergic asthma
Keywords: AHR, Airway hyperresponsiveness; BAL, Bronchoalveolar lavage; BMMCs, Bone marrow-derived mast cells; MCh, Methacholine; MMPs, Matrix metalloproteinases; PAS, Periodic acid-Schiff; PLA2, Phospholipase A2; PCA, Passive cutaneous anaphylaxis; TLR, Toll like
Vacuolin-1-modulated exocytosis and cell resealing in mast cells
Keywords: BMMCs, bone marrow-derived mast cells; BSA, bovine serum albumin; BSS, buffered salt solution; CCM, complete culture medium; CIM, complete Iscove's medium; DIDS, 4,4′-diisothiocyanatostilbene-2,2′-disulphonate; DIOA, (dihydroindenyl)oxy/alkanoic acid; DMS
Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation
Keywords: Oxysterol-binding protein; Oxysterol-binding protein-related protein; ORP9; PDK-2; Akt; Mast cells; Hydrophobic motif; PKCBIM, bisindolylmaleimide; BMMCs, bone marrow-derived mast cells; Btk, Bruton's tyrosine kinase; ER, endoplasmic reticulum; HM, hydrop
G protein-coupled receptors and the modification of FcɛRI-mediated mast cell activation
Keywords: BMMCs, bone marrow-derived mast cells; cAMP, cyclic adenosine monophosphate; EP, E prostanoid receptor; FcɛRI, high affinity IgE-receptor; GPCR, G protein-coupled receptor; IgE, immunoglobulin E; LPA, lysophosphatidic acid; LT, leukotriene; MIP-1α, macrop
Super-oxidized solution inhibits IgE-antigen-induced degranulation and cytokine release in mast cells
Keywords: SOS, super-oxidized solution; SCF, stem cell factor; MCs, mast cells; BMMCs, bone marrow-derived mast cells; CCL3/MIP1-α, macrophage inhibitory protein 1 alpha; IgE, Immunoglobulin E; FcεRI, High affinity-IgE receptor; NFAT, nuclear factor of activated T
Generation of adenosine A3 receptor functionally humanized mice for the evaluation of the human antagonists
Keywords: A3AR, adenosine A3 receptor; A3ARc/c mice, A3AR-chimeric mice; A3ARh/h mice, A3AR-humanized mice; BMMCs, bone marrow-derived mast cells; [Ca2+]i, intracellular Ca2+ concentration; Cl-IB-MECA, 2-chloro-N6-(3-iodobenzyl)adenosine-5′-N-methyluronamide; DT-A,