Keywords: C1P، سرامید-1-فسفات; 3-kdhSo, 3-ketodihydrosphingosine; aSMase, acid sphingomyelinase; aCDase, acid ceramidase; C1P, ceramide-1-phosphate; Cer, ceramide; CerK, ceramide kinase; CerS, ceramide synthases; CerT, ceramide transporter protein; cPLA2a, cytosolic phospholipase A2; D
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Specific sphingolipid content decrease in Cerkl knockdown mouse retinas
Keywords: C1P، سرامید-1-فسفات; knockout models; retinal dystrophy; sphingolipidSPL, Sphingolipid; DhSPL, Dihydrosphingolipid; CER, Ceramide; C1P, Ceramide-1-Phosphate; SPH, Sphingosine; S1P, Sphingosine-1-Phosphate; DhCER, Dihydroceramide; MHCer, Monohexosyl Ceramide; GlcCer, Glucosyl
Bioactive lipid mediators in skin inflammation and immunity
Keywords: C1P، سرامید-1-فسفات; AA, arachidonic acid; AEA, N-arachidonoyl ethanolamine; AG, arachidonoylglycerol; ALA, alpha-linolenic acid; BLT, leukotriene B receptor; C1P, ceramide-1-phosphate; CB, cannabinoid receptor; CER, ceramide; COX, cyclooxygenase; cPGES, cytosolic prostagland
Ceramide biosynthesis and metabolism in trophoblast syncytialization
Keywords: C1P، سرامید-1-فسفات; aSMase, acid sphingomyelinase; hCG, human chorionic gonadotropin; SM, sphingomyelin; CERK, ceramide kinase; SPL, sphingolipid; Sph, sphingosine; SPHK, sphingosine kinase; S1P, sphingosine-1-phosphate; C1P, ceramide-1-phosphate; PK, protein kinase; BCRP, b
A ceramide analog inhibits cPLA2 activity and consequent PGE2 formation in LPS-stimulated macrophages
Keywords: C1P، سرامید-1-فسفات; CERA-1, ceramide analogue-1; PCERA-1, phospho-ceramide analogue-1; AA, arachidonic acid; cPLA2, cytosolic phospholipase A2; PG, prostaglandin; COX, cyclooxygenase; NO, nitric oxide; C1P, ceramide-1-phosphate; S1P, sphingosine-1-phosphate; PC, phosphatidyl
Activation of mTOR and RhoA is a major mechanism by which ceramide 1-phosphate stimulates macrophage proliferation
Keywords: C1P، سرامید-1-فسفات; BSA, bovine serum albumin; C1P, ceramide-1-phosphate; ERK, extracellularly regulated kinase; FBS, fetal bovine serum; JNK, c-Jun terminal kinase; MAPK, mitogen activated protein kinase; M-CSF, macrophage-colony stimulating factor; MTS, [3-(4,5-dimethylthi
Hypoxia-induced neuronal apoptosis is mediated by de novo synthesis of ceramide through activation of serine palmitoyltransferase
Keywords: C1P، سرامید-1-فسفات; ACTB, Actin B; CERK, Ceramide kinase (EC 2.7.1.138); C1P, Ceramide-1-phosphate; DL-PPMP, dl-Threo-1-phenyl-2-palmitoylamino-3-morpho-lino-1-propanol; DTT, Dithiothreitol; FB1, Fumonisin B1; GCS, Glucosylceramide synthase (EC 2.4.1.80); LDH, Lactate dehydr
Newly synthetic ceramide-1-phosphate analogs; their uptake, intracellular localization, and roles as an inhibitor of cytosolic phospholipase A2α and inducer of cell toxicity
Keywords: C1P، سرامید-1-فسفات; C1P, ceramide-1-phosphate; PLA2, phospholipase A2; cPLA2α, α type cytosolic phospholipase A2; MM- and DM-C1P, mono- and di-methyl-ester analogs of C1P; CHO, Chinese hamster ovary; PAF, platelet-activating factor; PMA, 4β-phorbol 12-myristate 13-acetate; N
Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease
Keywords: C1P، سرامید-1-فسفات; BMDM, bone marrow-derived macrophages; C2-ceramide, N-acetylsphingosine; C8-ceramide, N-octanoylsphingosine; C1P, ceramide-1-phosphate; DAG, diacylglycerol; ERK, extracellular regulated kinase; GSH, glutathione; LPP, lipid phosphate phosphatase; MAPK, mit
Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro
Keywords: C1P، سرامید-1-فسفات; Cer, ceramide; CerK, ceramide kinase; C1P, ceramide-1-phosphate; DMB-Cer, N-(5-(5,7-dimethyl BODIPY)-l-pentanoyl)-d-erythro-sphingosine; DMECs, dermal microvascular endothelial cells; FCS, fetal calf serum; S1P, sphingosine-1-phosphate; S1PR, S1P receptor
Effects of ceramide, ceramidase inhibition and expression of ceramide kinase on cytosolic phospholipase A2α; additional role of ceramide-1-phosphate in phosphorylation and Ca2+ signaling
Keywords: C1P، سرامید-1-فسفات; PLA2, phospholipase A2; cPLA2α, type α cytosolic PLA2; AA, arachidonic acid; PKC, protein kinase C; ERK, extracellular signal-regulated kinase; C1P, ceramide-1-phosphate; PMA, 4β-phorbol myristate acetate; MAPP, (1S,2R)-D-erythro-2-(N-myristoylamino)-1-ph
Metabolism of sphingolipids in the gut and its relation to inflammation and cancer development
Keywords: C1P، سرامید-1-فسفات; Alk–SMase, alkaline sphingomyelinase; BSSL, bile salt stimulated lipase; C1P, ceramide-1-phosphate; CerS, ceramide synthase; COX, cyclooxygenase; CRC, colorectal cancer; GalCer, galactosylceramide; Glyco-SL, glycosphingolipid; IBD, inflammatory bowel dise
Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice
Keywords: C1P، سرامید-1-فسفات; Cer, ceramide; CerK, ceramide kinase; CerkL, ceramide kinase-like; C1P, ceramide-1-phosphate; DAGK, diacylglycerol kinase; KO, knockout; LPA, lysophosphatidic acid; PA, phosphatidic acid; PCR, polymerase chain reaction; PGP, phosphatidylglycerol phosphate
Involvement of nitric oxide in the promotion of cell survival by ceramide 1-phosphate
Keywords: C1P، سرامید-1-فسفات; A-SMase, acid sphingomyelinase; BMDM, bone marrow-derived macrophages; C1P, ceramide-1-phosphate; C2-, acetyl; C8-, octanoyl; CAPE, caffeic acid phenylethyl ester; DTT, diethyltreitol; FBS, fetal bovine serum; M-CSF, macrophage-colony stimulating factor;
Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells
Keywords: C1P، سرامید-1-فسفات; ACD5, accelerated cell death 5; BrdU, 5-bromo-2′-deoxyuridine; C1P, ceramide-1-phosphate; CerK, ceramide kinase; cPLA2, cytosolic phospholipase A2; EGF, epidermal growth factor; PARP, poly(ADP-ribose)polymerase; PCD, programmed cell death; siRNA, small in
Enhanced ceramide-induced apoptosis in ceramide kinase overexpressing cells
Keywords: C1P، سرامید-1-فسفات; CerK, ceramide kinase; C1P, ceramide-1-phosphate; Cer, ceramide; FACS, fluorescence-activated cell sorter; FCS, fetal calf serum; GlcCer, glucosylceramide; GCS, glucosylceramide synthase; NBD, nitrobenzo-2-oxa-1,3-diazole; SM, sphingomyelin; SMS, sphingom
Ceramide 1-phosphate/ceramide, a switch between life and death
Keywords: C1P، سرامید-1-فسفات; C2-ceramide, N-acetylsphingosine; C8-ceramide, N-octanoylsphingosine; CERK, ceramide kinase; C1P, ceramide-1-phosphate; DAG, diacylglycerol; ERK, extracellular regulated kinase; MAPK, mitogen-activated protein kinase; M-CSF, monocyte-colony stimulating fa
Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway
Keywords: C1P، سرامید-1-فسفات; A-SMase, acid sphingomyelinase; BMDM, bone marrow-derived macrophages; C1P, ceramide-1-phosphate; C2-, acetyl; C8-, octanoyl; CAPE, caffeic acid phenylethyl ester; EMSA, electromobility shift assay; FBS, fetal bovine serum; GAPDH, glyceraldehyde-3-phospha