Keywords: پروتئین کیناز وابسته به cGMP; AA; arachidonic acid; AM; acetoxymethyl; CalDAG-GEFI; calcium- and DAG-regulated guanine nucleotide exchange factor 1; COX; cyclooxygenase; DAG; diacylglycerol; FITC; fluorescein isothiocyanate; FSC; forward scatter; GS; stimulatory G-protein; IP3; inosit
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Keywords: پروتئین کیناز وابسته به cGMP; Environmental association analysis; Molecular epidemiology; Schistosoma mansoni; Disease phenotype; cGMP-dependent protein kinase; Follistatin; Parasite fecundity;
Keywords: پروتئین کیناز وابسته به cGMP; AGE; Advanced Glycation End products; ALDH2; aldehyde dehydrogenase 2; AngII; angiotensin II; BKCa; large conductance Ca2+-activated K+ channel; Ca2+; calcium; [Ca2+]c; cytosolic free Ca2+ concentration; CaD; caldesmon, CaM, calmodulin; cAMP; cyclic adeno
Keywords: پروتئین کیناز وابسته به cGMP; AMPK; AMP-activated protein kinase; cGMP; cyclic guanosine monophosphate; EDH; endothelium-dependent hyperpolarization; H2O2; hydrogen peroxide; NO; nitric oxide; NOS; nitric oxide synthase; PGs; prostaglandins; PKG; cGMP-dependent protein kinase; ROS; re
Keywords: پروتئین کیناز وابسته به cGMP; AS; Angeli's salt; AST; aspartate aminotransferase; ALT; alanine transaminase; BALF; bronchoalveolar lavage fluid; CGRP; calcitonin gene-related peptide; COX-2; cyclooxygenase-2; CFU; colony-forming unity; cGMP; cyclic guanosine monophosphate; PKG; cGMP-d
Keywords: پروتئین کیناز وابسته به cGMP; lHCC; hepatocellular carcinoma; ECM; extracellular matrix; FBLP-1; filamin binding LIM protein -1 (or Migfilin); VASP; vasodilator stimulated phosphoprotein; PBGD; porphobilinogen deaminase; PKA; cAMP-dependent kinase; PKG; cGMP-dependent protein kinase;
Keywords: پروتئین کیناز وابسته به cGMP; cNMPs; Nucleotidyl cyclases; Phosphodiesterases; Protein kinases; Bacterial toxins; Second messengers; AC; adenylyl cyclase; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CC; cytidylyl cyclase; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cGMP; guanos
Keywords: پروتئین کیناز وابسته به cGMP; cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cNMP; 3â²,5â²-cyclic nucleoside monophosphate; cUMP; uridine 3â²,5â²-cyclic monophosphate; cTMP; thymidine 3
Keywords: پروتئین کیناز وابسته به cGMP; Genetic variants; PRKG1; foraging; Maternal sensitivity; Development; Early adversity; Polymorphism; microRNA; Gene-environment interaction; cGMP-dependent protein kinase;
Activation of cyclic GMP-dependent protein kinase blocks alcohol-mediated cell death and calcium disruption in cerebellar granule neurons
Keywords: پروتئین کیناز وابسته به cGMP; Alcohol; cGMP-dependent protein kinase; Fetal alcohol spectrum disorder; Intracellular calcium; Neuroprotection;
Interleukin-15 derived from Guanylin-GC-C-expressing macrophages inhibits fatty acid synthase in adipocytes
Keywords: پروتئین کیناز وابسته به cGMP; dTg; double transgenic; ELISA; enzyme-linked immunosorbent assay; Fasn; fatty acid synthase; Gn; guanylin; GC-C; guanylyl cyclase C; HFD; high-fat diet; IL-2; interleukin-2; IL-2R; interleukin-2 receptor; IL-15; interleukin-15; IL-15R; interleukin-15 rece
Research ArticleFerulic acid-4-O-sulfate rather than ferulic acid relaxes arteries and lowers blood pressure in mice
Keywords: پروتئین کیناز وابسته به cGMP; 4-AP; 4-aminopyridine; Ach; acetylcholine; Ca2+/CaM; Ca2+/calmodulin; cGK; cGMP-dependent protein kinase; cGMP; cyclic guanosine monophosphate; COX; cyclooxygenase; FA; ferulic acid; FA-glu; FA-4-O-glucuronide; FA-sul; ferulic acid-4-O-sulfate; KRB; Krebs
Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells
Keywords: پروتئین کیناز وابسته به cGMP; CBS; cystathionine β-synthase; CSE; cystathionine γ-lyase; Drp1; dynamin-related protein 1; 15d-PGJ2; 15-deoxy-Î12,14-prostaglandin J2; ERK; extracellular signal-regulated kinase; G protein; GTP-binding protein; GC; guanylate cyclase; GDP; guanosine 5'
8-Nitro-cGMP promotes bone growth through expansion of growth plate cartilage
Keywords: پروتئین کیناز وابسته به cGMP; CNP; C-type natriuretic peptide; GC-B; Guanylate cyclase-coupled receptor-B; PKG;; cGMP-dependent protein kinase; L-NAME; L-NG-nitroarginine methyl ester; D-NAME; D-NG-nitroarginine methyl ester; EdU; 5-Ethyl-2â²-deoxyuridine; DAPI; 4â²,6-Diaminidino-2-
Riociguat: Mode of Action and Clinical Development in Pulmonary Hypertension
Keywords: پروتئین کیناز وابسته به cGMP; chronic thromboembolic pulmonary hypertension; pulmonary arterial hypertension; sGC stimulator; 6MWD; 6-minute walking distance; ADMA; asymmetric dimethylarginine; AE; adverse event; BH4; tetrahydrobiopterin; BMPR-2; bone morphogenetic protein receptor-2;
TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats
Keywords: پروتئین کیناز وابسته به cGMP; TRPV3; Carvacrol; Uterus; Radial artery; Pregnancy; TRPV3; transient receptor potential vanilloid type-3 channel; IHC; immunohistochemistry; NO; nitric oxide; NOS; nitric oxide synthase; sGC; soluble guanylate cyclase; PKG; cGMP-dependent protein kinase;
Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus
Keywords: پروتئین کیناز وابسته به cGMP; Nitric oxide; μ-Opioid receptor; Locus coeruleus; Cyclic guanosine monophosphate; Reactive oxygen species; Slice; Firing; A 350619; 3-[2-[(4-chlorophenyl)thiophenyl]-N-[4-(dimethylamino)butyl]-2-propenamide hydrochloride; aCSF; artificial cerebrospinal f
cNMP-AMs mimic and dissect bacterial nucleotidyl cyclase toxin effects
Keywords: پروتئین کیناز وابسته به cGMP; AM; acetoxymethylester; cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cNMP; 3â²,5â²-cyclic nucleoside monophosphate; cUMP; uridine 3â²,5â²-cyclic monophos
MiR-20a regulates the PRKG1 gene by targeting its coding region in pulmonary arterial smooth muscle cells
Keywords: پروتئین کیناز وابسته به cGMP; MicroRNA; cGMP-dependent protein kinase; Coding region; Pulmonary arterial smooth muscle cells; Hypoxia;
cGMP-dependent protein kinase I gamma encodes a nuclear localization signal that regulates nuclear compartmentation and function
Keywords: پروتئین کیناز وابسته به cGMP; PKGI; cGMP-dependent protein kinase I; NLS; nuclear localization signal; CREB; cAMP response element-binding protein; cGMP-dependent protein kinase; cGMP signal transduction; Nuclear translocation; Smooth muscle cell;
Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19)
Keywords: پروتئین کیناز وابسته به cGMP; ELISA; enzyme-linked immunosorbent assay; qRT-PCR; quantitative real-time reverse-transcription polymerase chain reaction; ER; estrogen receptor; SERM; selective estrogen receptor modulator; cAMP; cyclic adenosine monophosphate; ALP; alkaline phosphatase;
Nitroxyl (HNO) suppresses vascular Nox2 oxidase activity
Keywords: پروتئین کیناز وابسته به cGMP; cGMP; cyclic guanosine monophosphate; cGK; cGMP-dependent protein kinase; IPA/NO; isopropylamine NONOate; MCA; middle cerebral artery; ODQ; 1H-[1,2,4]-oxadiazolo[4,3-a]quinoxalin-1-one; PDBu; phorbyl 12,13-dibutyrate; ROS; reactive oxygen species; Rp-8-pC
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways
Keywords: پروتئین کیناز وابسته به cGMP; ANP; atrial natriuretic peptide; BATF; B-cell activating transcription factor; FKHR(Foxo1a); forkhead in human rhabdomyosarcoma; NPRA; natriuretic peptide receptor A; PI3K; phosphatidylinositol 3â²-kinase; PKG; cGMP-dependent protein kinase; ROR; retinoi
The cyclic GMP-dependent protein kinase Iα suppresses kidney fibrosis
Keywords: پروتئین کیناز وابسته به cGMP; cGMP; cGMP-dependent protein kinase; interstitial fibrosis; nitric oxide;
The ruthenium NO donor, [Ru(bpy)2(NO)SO3](PF6), inhibits inflammatory pain: Involvement of TRPV1 and cGMP/PKG/ATP-sensitive potassium channel signaling pathway
Keywords: پروتئین کیناز وابسته به cGMP; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CFA; complete Freund's adjuvant; cGMP; cyclic monophosphate guanosine; GLY; glybenclamide; HTAB; hexadecyltrimethylammonium bromide; KT5823; 2, 3, 9,10, 11, 12-hexahydro-10R-methoxy-2, 9-dime
The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma membrane of developing cerebellar granule cells
Keywords: پروتئین کیناز وابسته به cGMP; AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; AMPAR; AMPA receptor; Angeli's salt; disodium diazem-1-ium-1,2,2-triolate; CaCMKII; Ca2 +-calmodulin kinase II; cGK; cGMP-dependent protein kinase; cGKI; cGMP-dependent protein kinase type I; cGK
cGMP-dependent protein kinase I is involved in neurite outgrowth via a Rho effector, rhotekin, in Neuro2A neuroblastoma cells
Keywords: پروتئین کیناز وابسته به cGMP; NO; nitric oxide; cGK; cGMP-dependent protein kinase; GEF; guanine nucleotide exchange factor; GAP; GTPase-activating protein; 8-pCPT-cGMP; 8-(4-chlorophenylthio)-cGMP; RA; all-trans-retinoic acid; LPA; 1-oleoyl lysophosphatidic acid; VASP; vasodilator-st
Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice
Keywords: پروتئین کیناز وابسته به cGMP; PDE; phosphodiesterase; AED; antiepileptic drug; GBP; gabapentin; VGB; vigabatrin; PTZ; pentylenetetrazole; NO; nitric oxide; NOS; nitric oxide synthase; GC; guanylate cyclase; PKG; cGMP-dependent protein kinase; cGMP; guanosine 3â²,5â²-monophosphate; C
Redox modification of cell signaling in the cardiovascular system
Keywords: پروتئین کیناز وابسته به cGMP; AngII; angiotensin II; ASK1; apoptosis signal-regulating kinase 1; BDNF; brain-derived neurotrophic factor; BH4; tetrahydrobiopterin; CaMKII; Ca2+/calmodulin-dependent protein kinase II; cGMP; cyclic guanosine monophosphate; ETC; electron transport chain;
A guanosine 3â²,5â²-cyclic monophosphate (cGMP) reporter system based on the G-kinase/CREB/CRE signal transduction pathway
Keywords: پروتئین کیناز وابسته به cGMP; GC; guanylate cyclase; cGK; cGMP-dependent protein kinase; CRE; cAMP-responsive element; CREB; CRE binding protein; cAK; cAMP-dependent protein kinase; MMTV; mouse mammary tumor virus; Guanylate cyclase; cGMP; cGMP-dependent protein kinase; cAMP-responsiv
Nitric oxide regulates pulmonary vascular smooth muscle cell expression of the inducible cAMP early repressor gene
Keywords: پروتئین کیناز وابسته به cGMP; NO; nitric oxide; ICER; inducible cAMP early repressor; RPaSMC; rat pulmonary artery smooth muscle cells; VSMC; vascular smooth muscle cells; PKG; cGMP-dependent protein kinase; sGC; soluble guanylate cyclase; sGCα1â/â; mice deficient for the soluble
The amino terminus of cGMP-dependent protein kinase Iβ increases the dynamics of the protein's cGMP-binding pockets
Keywords: پروتئین کیناز وابسته به cGMP; PKG; cGMP-dependent protein kinase; PKA; cAMP-dependent protein kinase; DXMS; deuterium exchange mass spectrometry; H/D; hydrogen/deuterium; cNBD; cyclic nucleotide binding domain; PKG; cGMP-affinity; Leucine zipper; Hydrogen exchange; Mass spectrometry;
Several agents and pathways regulate lipolysis in adipocytes
Keywords: پروتئین کیناز وابسته به cGMP; Lipolysis; Adipose tissue; Intracellular signalling pathways; Hormone-sensitive lipase; Adipose triglyceride lipase; Antilipolysis; ACTH; adrenocorticotrophin hormone; AdPLA; adipose-specific phospholipase A2; Ang II; angiotensin II; ANP; atrial natriuret
Pain and analgesia: The dual effect of nitric oxide in the nociceptive system
Keywords: پروتئین کیناز وابسته به cGMP; 7-NI; 7-nitroindazole; AA; arachidonic acid; Ach; acetylcholine; AG; aminoguanidine hemisulfate; AKT; protein kinase B; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATP; adenosine triphosphate; CFA; complete Freund's adjuvant; cGMP; cycl
cGMP-dependent protein kinase Type I promotes CREB/CRE-mediated gene expression in neurons of the lateral amygdala
Keywords: پروتئین کیناز وابسته به cGMP; cGMP-dependent protein kinase; Lateral amygdala; cAMP-response element binding protein; Transcription
Investigating the role of protein kinase-G in the antidepressant-like response of sildenafil in combination with muscarinic acetylcholine receptor antagonism
Keywords: پروتئین کیناز وابسته به cGMP; Phosphodiesterase 5; cGMP-dependent protein kinase; Sildenafil; Antidepressant; Forced swim test; 8-Br-cGMP; Atropine; Cholinergic
A protein phosphorylation-based assay for screening and monitoring of drugs modulating cyclic nucleotide pathways
Keywords: پروتئین کیناز وابسته به cGMP; Phosphodiesterase inhibitors; Nitric oxide donors; Prostaglandins; cGMP; cAMP; cGMP-dependent protein kinase; cAMP-dependent protein kinase; VASP
(d)-Amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Iα
Keywords: پروتئین کیناز وابسته به cGMP; cGMP; cyclic guanosine 3â²,5â²-mono-phosphate; i.p.; intraperitoneal; i.v.; intravenous; Ki; inhibition constant; MAP; mean arterial blood pressure; Km; Michaelis-Menten constant; MPP; membrane-permeable peptides; PKA; cAMP-dependent protein kinase; P
Secreted amyloid precursor protein-α upregulates synaptic protein synthesis by a protein kinase G-dependent mechanism
Keywords: پروتئین کیناز وابسته به cGMP; Secreted APPα; Protein synthesis; Synaptic plasticity; Synaptoneurosome; cGMP-dependent protein kinase; Aging
Predicting the activity of drugs for a group of imidazopyridine anticoccidial compounds
Keywords: پروتئین کیناز وابسته به cGMP; Anticoccidial drug; Gene expression programming; cGMP-dependent protein kinase; Quantitative structure–activity relationships
The search for a pathophysiological link between gender, cardiac endocrine function, body mass regulation and cardiac mortality: Proposal for a working hypothesis
Keywords: پروتئین کیناز وابسته به cGMP; ANP; Atrial Natriuretic Peptide, COOH-terminal fragment of proANP; BMI; Body mass index; BNP; Brain (or B-type) Natriuretic Peptide, COOH-terminal fragment of proBNP; cAMP; Cyclic adenosine 3â²,5â²-monophosphate; cGMP; Cyclic guanosine 3â²,5â²-monopho
cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity
Keywords: پروتئین کیناز وابسته به cGMP; cGMP-dependent protein kinase; Anchoring proteins; IRAG; Nuclear translocation; Transcriptional regulation; cGMP signal transduction
Phosphorylation of the PKG substrate, vasodilator-stimulated phosphoprotein (VASP), in human cultured prostatic stromal cells
Keywords: پروتئین کیناز وابسته به cGMP; Prostate; Prostatic stromal cells; cGMP-dependent protein kinase; cGMP; Vasodilator-stimulated phosphoprotein; Nitric oxide
Hyposmotic stimulation-induced nitric oxide production in outer hair cells of the guinea pig cochlea
Keywords: پروتئین کیناز وابسته به cGMP; OHCs; outer hair cells; [Ca2+]i, intracellular Ca2+ concentrations; TRPV4; transient receptor potential vanilloid 4; NO; nitric oxide; nitric oxide synthase; NOS; nNOS; neuronal nitric oxide synthase; eNOS; endothelial nitric oxide synthase; IHCs; inner h
Signalling via cGMP: Lessons from Drosophila
Keywords: پروتئین کیناز وابسته به cGMP; cGMP; Drosophila; Renal tubules; cGMP-dependent protein kinase; Phosphodiesterase;
Expression of cGMP-dependent protein kinases (I and II) and neuronal nitric oxide synthase in the developing rat cerebellum
Keywords: پروتئین کیناز وابسته به cGMP; Nitric oxide synthase; cGMP-dependent protein kinase; Rat cerebellum; Quantitative RT-PCR;
Role of the Small Heat Shock Proteins in Regulating Vascular Smooth Muscle Tone
Keywords: پروتئین کیناز وابسته به cGMP; HSP; heat shock protein; HSV; human saphenous vein; IEF; isoelectric focusing; PAGE; polyacrylamide gel electrophoresis; PCA; pig coronary artery; PKA; cAMP-dependent protein kinase; PKG; cGMP-dependent protein kinase; SDS; sodium dodecyl sulfate; SNP; so
Species- and tissue-dependent effects of NO and cyclic GMP on cardiac ion channels
Keywords: پروتئین کیناز وابسته به cGMP; cGMP; Nitric oxide; Cardiac tissue; Ion channels; cAMP; Cyclic nucleotide phosphodiesterases; cGMP-dependent protein kinase; L-type calcium current;
Nitric oxide reduces T lymphocyte adhesion to human brain microvessel endothelial cells via a cGMP-dependent pathway
Keywords: پروتئین کیناز وابسته به cGMP; T cell; Leukocyte; cGMP-dependent protein kinase; Adhesion molecule; Tumor necrosis factor-alpha; E-selectin; ICAM-1 (intercellular adhesion molecule 1);
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4
Keywords: پروتئین کیناز وابسته به cGMP; ACE; angiotensin-converting enzyme; ACh; acetylcholine; AGE; advanced glycation end products; cGK-I; cGMP-dependent protein kinase; DHE; dihydroethidium; DPI; diphenyleneiodonium chloride; DTPA; diethylenetriaminepentaacetic acid; DTT; dithiothreitol; EPR