Keywords: CHC، هپاتیت مزمن C; ALT, Alanine aminotransferase; APRI, Aspartate transaminase to platelet ratio index; AST, Aspartate transaminase; CHC, Chronic hepatitis C; CLD, Chronic liver disease; CT, Computed tomography; EASL, European Association for the Study of the Liver; HCC, He
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Keywords: CHC، هپاتیت مزمن C; CHC, Chronic hepatitis C; PEG, Pegylated; SVR, Sustained virological response; RCT, Randomized controlled trial; HCV, Hepatitis C virus; KPS, Karnofsky performance status
Association between IFNL4 rs368234815 polymorphism and sustained virological response in chronic hepatitis C patients undergoing PEGylated interferon/ribavirin therapy: A meta-analysis
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; HCV, hepatitis C virus; IFNL4, interferon lambda 4; OR, odds ratio; peg-IFN, pegylated interferon; RBV, ribavirin; SNP, single nucleotide polymorphism; SVR, sustained virological responseIFNL4; CHC; SVR; PEG-IFN/RBV; Meta-analysi
Influence of IL10 Gene polymorphisms on the sustained virologic response of patients with chronic hepatitis C to PEG-interferon/ribavirin therapy
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; CI, confidence intervals; HCV, hepatitis C virus; HWE, Hardy–Weinberg equilibrium; IL10, interleukin 10; OR, odds ratio; PEG-IFN-a, pegylated interferon alpha; SNPs, single-nucleotide polymorphisms; SVR, sustained virological res
Host – hepatitis C viral interactions: The role of genetics
Keywords: CHC، هپاتیت مزمن C; AHC, acute hepatitis C; CHC, chronic hepatitis C; CNV, copy number variant; CRS, cirrhosis risk score; DC, dendritic cell; EWAS, epigenome-wide association study; GWAS, genome wide association study; HBV, hepatitis B virus; HCV, hepatitis C virus; HCC, he
PNPLA3 gene in liver diseases
Keywords: CHC، هپاتیت مزمن C; GWAS, genome-wide association studies; CHC, chronic hepatitis C; SNP, single nucleotide polymorphism; HCV, hepatitis C virus; PNPLA3, patatin-like phospholipase domain containing 3; NAFLD, nonalcoholic fatty liver disease; ALT, alanine aminotransferase; B
Interferon lambda-3 is not associated with clinical outcome in patients with HCV-induced compensated cirrhosis: A long-term cohort study
Keywords: CHC، هپاتیت مزمن C; HCV, chronic hepatitis C virus; CHC, chronic hepatitis C; APRI, AST to platelet ratio index; MELD, model for end stage liver disease; EV, esophageal varices; ESLD, end stage liver disease; HCC, hepatocellular carcinoma; LT, liver transplant; IFN, interfer
Optimal Duration of Pegylated Interferon Plus Ribavirin Therapy for Chronic Hepatitis C Genotype 3 Patients who do not Achieve Rapid Virological Response
Keywords: CHC، هپاتیت مزمن C; 36 weeks therapy; chronic hepatitis C; pegylated interferon; ribavirin; RVR non-achieversHCV, Hepatitis C virus; CHC, Chronic hepatitis C; SVR, sustained virologic response; EVR, early virological response; HIV, Human Immunodeficiency virus; HBV, hepatiti
Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease
Keywords: CHC، هپاتیت مزمن C; AST, aspartate aminotransferase; ALT, alanine aminotransferase; BMI, body mass index; CHB, chronic hepatitis B; CHC, Chronic hepatitis C; HOMA-IR, homeostasis model assessment; HBsAg, hepatitis B surface antigen; IR, insulin resistance; NAFLD, non-alcohol
Divergent effects of type-I interferons on regulatory T cells
Keywords: CHC، هپاتیت مزمن C; APC, antigen-presenting cell; cAMP, cyclic adenosine monophosphate; CHC, chronic hepatitis C; IFN, interferon; IFNAR, interferon α/β receptor; IL, interleukin; IRF, interferon regulatory factor; IRFE, interferon regulatory factor-binding element; ISG, int
Early predictive efficacy of core antigen on antiviral outcomes in genotype 1 hepatitis C virus infected patients
Keywords: CHC، هپاتیت مزمن C; HCV, hepatitis C virus; PegIFN, pegylated interferon; RBV, ribavirin; DAA, direct acting antiviral; CHC, chronic hepatitis C; SVR, sustained virologic response; LLOD, lower limit of detection; HCVcAg, HCV core antigen; YPegIFN, type Y pegylated interferon
Sustained Virological Response Rates to Antiviral Therapy in Genotype 1 and 3 Chronic Hepatitis C Patients: A Study from North India
Keywords: CHC، هپاتیت مزمن C; hepatitis C virus; liver disease; interferon; antivirals; sustained viral responseALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CHC, chronic hepatitis C; ETR, end of treatment response; EVR, early virological respon
Predictive factors for adverse dermatological events during pegylated/interferon alpha and ribavirin treatment for hepatitis C
Keywords: CHC، هپاتیت مزمن C; HCV, hepatitis C virus; Peg IFN-α, pegylated interferon-alpha; DAAs, direct-acting antiviral agents; CHC, chronic hepatitis C; AEs, adverse events; IFN-α, interferon-alpha; SVR, sustained virologic response; LP, lichen planus; DRESS, drug reaction with eo
Efficacy and safety of peginterferon plus ribavirin for patients aged ≥ 65 years with chronic hepatitis C: A systematic review and meta-analysis
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; SVR, sustained virological response; RVR, rapid virological response; EVR, early virological response; ETR, end-of-treatment virological response; HCV, hepatitis C virus; CI, confidence interval; ITT, intention-to-treat; PP, per-
Therapy of chronic hepatitis C virus infection in the era of direct-acting and host-targeting antiviral agents
Keywords: CHC، هپاتیت مزمن C; Chronic hepatitis C; Direct-acting antivirals; Host-targeting antivirals; Interferon; Protease inhibitors; RibavirinBOC, boceprevir; CHC, chronic hepatitis C; CV, cryoglobulinemic vasculitis; DAA, direct-acting antiviral; DVR, delayed virological response
Keywords: CHC، هپاتیت مزمن C; Vitamin D deficiency; Parathyroid hormone; Chronic hepatitis C; Health problem; Calcium; PhosphateVitD, vitamin D; CHC, chronic hepatitis C; PTH, parathyroid hormone; CVs, coefficients of variation
Longitudinal assessment of liver stiffness in patients undergoing antiviral treatment for hepatitis C
Keywords: CHC، هپاتیت مزمن C; AR, attributable risk; CHC, chronic hepatitis C; CLD, chronic liver diseases; HCV, hepatitis C virus; IQR, interquartile range; NR, null response; RR, relative risk; SOC, standard of care; SVR, sustained virologic response; TE, transient elastographyAntiv
Interleukin-28B rs12979860C/T and rs8099917T/G contribute to spontaneous clearance of hepatitis C virus in Caucasians
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; CI, confidence interval; GWAS, genome-wide association study; HBV, hepatitis B virus; HCV, hepatitis C virus; HIV, human immunodeficiency virus; IFN, interferon; IL28B, interleukin-28B; kbs, kilobases; NA, not available; ORs, odd
Th1 and Th2 cytokine profiles induced by hepatitis C virus F protein in peripheral blood mononuclear cells from chronic hepatitis C patients
Keywords: CHC، هپاتیت مزمن C; HCV, hepatitis C virus; CHC, chronic hepatitis C; HCC, hepatocellular carcinoma; Th, T helper; F protein, alternate reading frame protein; PBMC, peripheral blood mononuclear cells; HLA, human leukocyte antigen; ELISA, enzyme-linked immunosorbent assay; EL
Host interleukin-28B genetic variants versus viral kinetics in determining responses to standard-of-care for Asians with hepatitis C genotype 1
Keywords: CHC، هپاتیت مزمن C; ALT, alanine aminotransferase; AST, aspartate aminotransferase; APRI, the aspartate aminotransferase-to-platelet ratio index; CHC, chronic hepatitis C; EOTVR, end-of-treatment virological response; GWAS, genome-wide associated studies; HCV, hepatitis C vi
Interleukin-28B polymorphisms on the SVR in the treatment of naïve chronic hepatitis C with pegylated interferon-α plus ribavirin: A meta-analysis
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; CI, confidence interval; GWAS, genome-wide association study; HCV, hepatitis C virus; HIV, human immunodeficiency virus; IL, interleukin; OR, odds ratio; PEG-IFN-α, pegylated interferon-alpha; RVR, rapid virological response; SNP
Circulating Microparticles as Disease-Specific Biomarkers of Severity of Inflammation in Patients With Hepatitis C or Nonalcoholic Steatohepatitis
Keywords: CHC، هپاتیت مزمن C; Noninvasive Assay; Lymphocyte; Serum Assay; Biomarker AssayALT, alanine aminotransferase; AUROC, areas under the receiver operating characteristics; CHC, chronic hepatitis C; FACS, fluorescence-activated cell sorting; HSC, hepatic stellate cells; iNKT, in
Diagnostic value of multiple biomarker panel for prediction of significant fibrosis in chronic hepatitis C
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; APRI, AST to platelet ratio index; AUROC, area under the receiver-operating–characteristic curve; AST, aspartate aminotransferaseChronic hepatitis C; Liver fibrosis; Biomarker
Prediction on liver fibrosis using different APRI thresholds when patient age is a categorical marker in patients with chronic hepatitis B
Keywords: CHC، هپاتیت مزمن C; HBV, Hepatitis B virus; CHB, Chronic hepatitis B; HCC, Hepatocellular carcinoma; PLT, Platelet; ASPRI, Age-spleen-PLT ratio index; APRI, Aspartate aminotransferase (AST)-to-PLT ratio index; HBsAg, Hepatitis B surface antigen; CHC, Chronic hepatitis C; HE,
No increase in depression with low-dose maintenance peginterferon in prior non-responders with chronic hepatitis C
Keywords: CHC، هپاتیت مزمن C; ANOVA, Analysis of variance; BDI-II, Beck Depression Inventory II; CHC, Chronic hepatitis C; CIDI, Composite International Diagnostic Interview; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders-IV; HALT-C, Hepatitis C Antiviral Long-term Trea
Non-invasive assessment of hepatic fat accumulation in chronic hepatitis C by 1H magnetic resonance spectroscopy
Keywords: CHC، هپاتیت مزمن C; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CHC, chronic hepatitis C; HCL, hepatocellular lipids; HCV, hepatitis C virus; HOMA-IR, homeostasis model assessment index; MRS, magnetic resonance spectroscopy; NAFLD, non-alcoholic fatty liv
Enhanced expression of lymphomagenesis-related genes in peripheral blood B cells of chronic hepatitis C patients
Keywords: CHC، هپاتیت مزمن C; ACTB, actin beta; AID, activation-induced cytidine deaminase; ELISA, enzyme-linked immunosorbent assay; CHC, chronic hepatitis C; HCV, hepatitis C virus; NHL, non-Hodgkin's lymphoma; PBMCs, peripheral blood mononuclear cells; RT-PCR, reverse-transcription
Prevalence and Challenges of Liver Diseases in Patients With Chronic Hepatitis C Virus Infection
Keywords: CHC، هپاتیت مزمن C; Hepatitis C Virus; Burden of Disease; Hepatic Comorbidities; PrevalenceAASLD, American Association for the Study of Liver Diseases; CHC, chronic hepatitis C; ECC, extrahepatic cholangiocarcinoma; HCC, hepatocellular carcinoma; HIV, human immunodeficiency
Functional phenotypes and gene expression profiles of peripheral blood mononuclear cells in chronic hepatitis C patients who developed non-Hodgkin’s B-cell lymphoma
Keywords: CHC، هپاتیت مزمن C; AID, activation-induced cytidine deaminase; CARD, caspase recruitment domain; CHC, chronic hepatitis C; HCV, hepatitis C virus; B-NHL, B-cell non-Hodgkin’s lymphoma; NK, natural killer; PBMCs, peripheral blood mononuclear cellsHCV; Non-Hodgkin’s B-cell ly
Ursodeoxycholic acid induces glutathione synthesis through activation of PI3K/Akt pathway in HepG2 cells
Keywords: CHC، هپاتیت مزمن C; ROS, reactive oxygen species; UDCA, ursodeoxycholic acid; CHC, chronic hepatitis C; ALT, alanine aminotransferase; PI3K, phosphatidylinositol 3-kinase; Nrf2, nuclear factor-E2-related factor-2; GCL, glutamine-cysteine ligase; GSHS, GSH synthetase; CDCFH,
Hepatic IL-17 responses in human and murine primary biliary cirrhosis
Keywords: CHC، هپاتیت مزمن C; IL-17; Primary biliary cirrhosis; IL-2 receptor alpha; Liver; CD46; Tr1; Microenvironment; CD4+ T cellsAIH, autoimmune hepatitis; APC, antigen presenting cell; CHC, chronic hepatitis C; EAE, experimental autoimmune encephalomyelitis; IL-2Rα KO, interleuki
Association between transforming growth factor-beta 1 polymorphism and virologic characteristics of chronic hepatitis C
Keywords: CHC، هپاتیت مزمن C; ALT, alanine aminotransferase; anti-HCV, HCV antibody; AST, aspartate aminotransferase; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; CHC, chronic hepatitis C; CI, confidence interval; OR, odds ratio; PCR, polymerase chain reaction; SNP, single n
Correlation of FIBROSpect II With Histologic and Morphometric Evaluation of Liver Fibrosis in Chronic Hepatitis C
Keywords: CHC، هپاتیت مزمن C; APRI, aspartate aminotransferase to platelet ratio index; AUROC, area under the receiver operating characteristic curve; CHC, chronic hepatitis C; FSII, FIBROSpect II; HCV, hepatitis C virus; ROC, receiver operating characteristic curve analysis
Daily Cannabis Use: A Novel Risk Factor of Steatosis Severity in Patients With Chronic Hepatitis C
Keywords: CHC، هپاتیت مزمن C; BMI, body mass index; CHC, chronic hepatitis C; CI, confidence interval; OR, odds ratio
Interplay between oxidative stress and hepatic steatosis in the progression of chronic hepatitis C
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; HCV, hepatitis C virus; HAI, hepatitis activity index; HOMA-IR, homeostasis model assessment of insulin resistance; MDA-HSA, malondialdehyde adducted human serum albuminOxidative stress; Steatosis; Lipid peroxidation; HCV infecti
Insulin Resistance in Chronic Hepatitis C: Association With Genotypes 1 and 4, Serum HCV RNA Level, and Liver Fibrosis
Keywords: CHC، هپاتیت مزمن C; BMI, body mass index; CHB, chronic hepatitis B; CHC, chronic hepatitis C; HBV, hepatitis B virus; HCV, hepatitis C virus; HOMA-IR, Homeostasis Model for Assessment of Insulin Resistance; IR, insulin resistance
Hepatitis C Virus Replicates in the Same Immune Cell Subsets in Chronic Hepatitis C and Occult Infection
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; IFN, interferon; IL, interleukin; IRES, internal ribosomal entry site; mAb, monoclonal antibody; NAH, nucleic acid hybridization; NS5A, nonstructural protein 5A; PBMC, peripheral blood mononuclear cell; PHA, phytohemagglutinin; R
Disease Progression in Chronic Hepatitis C: Modifiable and Nonmodifiable Factors
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; HAART, highly active antiretroviral therapy; HIV-1, human immunodeficiency virus type 1
Percutaneous Liver Biopsy Is Safe in Chronic Hepatitis C Patients With End-Stage Renal Disease
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; CT, computerized tomography; dDAVP, deamino-8-D-arginine vasopressin; ESRD, end-stage renal disease; PCNB, percutaneous liver biopsy; PT, prothrombin time.
Phase 2 study of the combination of merimepodib with peginterferon-α2b, and ribavirin in nonresponders to previous therapy for chronic hepatitis C
Keywords: CHC، هپاتیت مزمن C; PEG-IFN-α, peginterferon-α2b (PEG-Intron™/ViraferonPeg™); RBV, ribavirin; CHC, chronic hepatitis C; SVR, sustained virological response; HCV, hepatitis C virus; MMPD, merimepodib; IMPDH, inosine monophosphate dehydrogenase; IFN-α, interferon-α; ALT, alani
Complementary and Alternative Medicine in Hepatology: Review of the Evidence of Efficacy
Keywords: CHC، هپاتیت مزمن C; ALD, alcoholic liver disease; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CAM, complementary and alternative medicine; CHC, chronic hepatitis C; FDA, Food and Drug Administration; HBeAg, hepatitis B e antigen; HBV, hepatitis B virus; H
Reciprocal Effects of Micro-RNA-122 on Expression of Heme Oxygenase-1 and Hepatitis C Virus Genes in Human Hepatocytes
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; CNS3, HCV replicon expressing HCV subgenomic protein core through nonstructural protein 3; CoPP, cobalt protoporphyrin; DGCR8, the DiGeorge syndrome critical region gene 8; GAPDH, glyceraldehyde phosphate dehydrogenase; HCV, hepa
Relationship of Smoking and Fibrosis in Patients With Chronic Hepatitis C
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; HCV, hepatitis C virus; s-Flt, fms-like tyrosine kinase receptor; s-KDR, kinase insert domain receptor; VEGF, vascular endothelial growth factor
Rapid Decline of Viral RNA in Hepatitis C Patients Treated With VX-950: A Phase Ib, Placebo-Controlled, Randomized Study
Keywords: CHC، هپاتیت مزمن C; CHC, chronic hepatitis C; HCV, hepatitis C virus; q8h, every 8 hours; q12h, every 12 hours
Polymorphism of interferon–gamma gene at position +874 and clinical characteristics of chronic hepatitis C
Keywords: CHC، هپاتیت مزمن C; CA, cytosine adenine; CHC, chronic hepatitis C; CI, confidence interval; ELISA, enzyme-linked immunosorbent assay; HAI, histological activity index; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; HCV, hepatitis C virus; IFN, interferon; IL, i
Viral and metabolic factors influencing alanine aminotransferase activity in patients with chronic hepatitis C
Keywords: CHC، هپاتیت مزمن C; Cholesterol; Triglyceride; Sustained virological response; Ribavirin; Peginterferon alfa-2a (40KD)ALT, alanine aminotransferase; BMI, body mass index; CHC, chronic hepatitis C; HCV, hepatitis C virus; SVR, sustained virological response
Relationship Between Steatosis, Inflammation, and Fibrosis in Chronic Hepatitis C: A Meta-Analysis of Individual Patient Data
Keywords: CHC، هپاتیت مزمن C; BMI, body mass index; CHC, chronic hepatitis C
Different viral kinetics between hepatitis C virus genotype 1 and 2 as on-treatment predictors of response to a 24-week course of high-dose interferon-alpha plus ribavirin combination therapy
Keywords: CHC، هپاتیت مزمن C; ALT, alanine transaminase; CHC, chronic hepatitis C; CPMP, Committee for Proprietary Medicinal Products; EVR, early virological response; HCV, hepatitis C virus; HCV-1, HCV genotype 1; HCV-2, HCV genotype 2; ICH, International Conference on Harmonization;
Cost-effectiveness of peginterferon alfa-2a (40 kDa) plus ribavirin in patients with HIV and hepatitis C virus co-infection
Keywords: CHC، هپاتیت مزمن C; AASLD, American Association for the Study of Liver Disease; APRICOT, AIDS Pegasys Ribavirin International Co-infection Trial; CHC, chronic hepatitis C; DC, decompensated cirrhosis; EVR, early virological response; HCV, hepatitis C virus; HCC, primary hepa