Keywords: Atherosclerosis; Cardiovascular diseases; Cell cycle; Proliferation; Pulmonary hypertension; Restenosis; Signaling pathway; Vascular smooth muscle cells; ACE; angiotensin converting enzyme; aFGF; acidic FGF; Ang II; angiotensin II; AP-1; activating protei
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Keywords: AIF; apoptosis-inducing factor; APC; anaphase promoting complex; ATG; autophagy-related; BH; Bcl-2 homology domain; BIR; baculovirus IAP repeat; CAK; CDK-activating kinase; CKI; CDK inhibitor; CPC; chromosomal passenger complex; CSC; checkpoint slide clam
Keywords: APC/C; anaphase-promoting complex/cyclosome; BM; bone marrow; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; CXCL12; chemokine (C-X-C motif) ligand 12; HSC; hematopoietic stem cell; Hsc70; heat shock cognate protein 70; LAP; latency
Keywords: PTH; parathyroid hormone; DTT; dithiothreitol; RP-HPLC; reverse-phase high-performance-liquid-chromatography; SDS-PAGE; sodium dodecyl sulfate and polyacrylamide gel electrophoresis; OPN; osteopontin; BSP; bone sialoprotein; ECM; extracellular matrix; Ca-
Metal- and redox homeostasis in prostate cancer with vitamin D3 supplementation
Keywords: Al; aluminium; ALT; alanine transaminase; AP-1; activated protein-1; AR; androgen receptor; AST; aspartate transaminase; B; boron; Ba; barium; BMI; body mass index; Ca; calcium; CDK4; cyclin dependent kinase; CEA; carcynoembrionic antigene; Chol; choles
Re-evaluating the role of FOXOs in cancer
Keywords: RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen
Pharmacokinetics and cytotoxic study of euphol from Euphorbia umbellata (Bruyns) Pax latex
Keywords: Euphol; Cell culture; Cytotoxic activity; UHPLC-MS; Euphorbia; Pharmacokinetics; 1D and 2D NMR; one and two dimension nuclear magnetic resonance spectroscopy; ACN; acetonitrile; ATCC; american type culture collection; CDCl3; deuterated chloroform; CDK; cy
A partnership with the proteasome; the destructive nature of GSK3
Keywords: AMPK; AMP-activated protein kinase; ARE; antioxidant response element; β-TrCP; beta-transducin repeat containing protein; CKI; casein kinase-1; CHD; chromatin helicase DNA-binding factor; CRY; cryptochrome; EMT; epithelial-mesenchymal transition; FGD; fa
The activation of STIM1 mediates S-phase arrest and cell death in paraquat induced acute lung intoxication
Keywords: ALI; acute lung injury; 2-APB; 2-Aminoethoxydiphenyl borate; BSA; bovine serum albumin; CCNA/CCND/Cyclin A/D; mammalian A/D-type Cyclin; CDK; Cyclin dependent kinase; CKI; Cyclin dependent kinase inhibitor; CRISPR-CAS9; clustered regularly interspaced sho
Short communicationPhosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis
Keywords: 7DHC; 7-dehydrocholesterol; AMPK; AMP-activated protein kinase; CaMKII; calmodulin-dependent kinase II; CHO; Chinese hamster ovary; CKI; casein kinase I; DHCR7; 7-dehydrocholesterol reductase; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; PBGD; porphob
Agastache rugosa Kuntze extract, containing the active component rosmarinic acid, prevents atherosclerosis through up-regulation of the cyclin-dependent kinase inhibitors p21WAF1/CIP1 and p27KIP1
Keywords: AKT; phosphatidylinositol 3-kinase-linked protein kinase; A.rugose; Agastacherugosa Kuntze; BrdU; bromodeoxyuridine; CA; caffeic acid; CCK-8; cell counting Kit-8; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; DAD; diode array UV/VI
GATA4 Is Sufficient to Establish Jejunal Versus Ileal Identity in the Small Intestine
Keywords: Transcriptional Regulation; Jejunal Identity; Enterohepatic Signaling; Fgf15; FXR; bio-ChIP-seq; biotin-mediated chromatin immunoprecipitation with high-throughput sequencing; bp; base pair; cDNA; complementary DNA; cKI; conditional knock-in; cKO; conditi
G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling
Keywords: GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinases; SA-β-Gal; senescence-associated-β-galactosidase; FACS; fluorescence-activated cell sorting; CCK-8; cell counting kit-8; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase
Identification, expression pattern and functional characterization of As-kip2 in diapause embryo restarting process of Artemia sinica
Keywords: As-kip2; p57Kip2 mRNA from Artemia sinica; As-KIP2; p57Kip2 protein from Artemia sinica; As-CARP-1; cell cycle and apoptosis regulator 1 protein from Artemia sinica; As-SODD; silencer of death domain protein from Artemia sinica; CDK; cyclin-dependent kina
Acute kidney injury following hepatectomy for hepatocellular carcinoma: incidence, risk factors and prognostic value
Keywords: AKI; acute kidney injury; KDIGO; kidney disease improving global outcomes; HCC; hepatocellular carcinoma; sCr; serum creatinine; RRT; renal replacement therapy; CKI; chronic kidney injury; eGFR; estimated glomerula filtration rate; ICU; intensive care uni
PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line
Keywords: α3 nAChR; alpha 3 nicotinic Acetylcholine Receptor; ATRA; all-trans Retinoic Acid; BMP-2; Bone morphogenetic protein-2; CCHS; Congenital Central Hypoventilation Syndrome; Cdk; cyclin-dependent kinase; ChIP; chromatin immunoprecipitation; CKI; Cdk inhibit
Opposing actions of the synapse-associated protein of 97-kDa molecular weight (SAP97) and Disrupted in Schizophrenia 1 (DISC1) on Wnt/β-catenin signaling
Keywords: APC; Adenomatous Polyposis Coli protein; CKI; casein kinase-1; DISC1; Disrupted in Schizophrenia 1; DLG1; discs large 1; GSK3β; glycogen synthase kinase 3 beta; HEK; human embryonic kidney; LEF; lymphocyte enhancer-binding factor; PSD; postsynaptic densi
APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription
Keywords: AP-1; activating protein 1; APPL; adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif; CKI; casein kinase I; Dvl; Dishevelled; GST; glutathione S-transferase; JNK; c-Jun N-terminal kinase; LRP; lo
Upregulation of cyclin-dependent kinase inhibitors CDKN1B and CDKN1C in hepatocellular carcinoma-derived cells via goniothalamin-mediated protein stabilization and epigenetic modifications
Keywords: Cyclin-dependent kinase inhibitor; CKI; Goniothalamin; Cell cycle; Hepatocellular carcinoma-derived cells; Epigenetic modification
Antiproliferative activity of the isoindigo 5â²-Br in HL-60 cells is mediated by apoptosis, dysregulation of mitochondrial functions and arresting cell cycle at G0/G1 phase
Keywords: Isoindigo; Anticancer; Apoptosis; Mitochondria dysfunction; Cell cycle; CDK; 5â²-Br; [(E)-1-(5â²-bromo-2â²-oxoindolin-3â²-ylidene)-6-ethyl-2,3,6,9-tetrahydro-2,9-dioxo-1H-pyrrolo[3,2-f]quinoline-8-carboxylic acid]; ÎΨm; difference in mitochondrial t
Associate editor: B. TeicherCo-targeting BRAF and cyclin dependent kinases 4/6 for BRAF mutant cancers
Keywords: BRAF V600E; Melanoma; CDK4/6 inhibitor; Abemaciclib; Cyclin D1; Resistance; CDK; Cyclin dependent kinase; MAPK; Mitogen activated protein kinase; RTK; Receptor tyrosine kinase; CKI; CDK inhibitory protein; EGFR; Epidermal growth factor receptor; PI3K; Pho
Loss of p27 phosphorylation at Ser10 accelerates early atherogenesis by promoting leukocyte recruitment via RhoA/ROCK
Keywords: apoEâ/â; apolipoprotein E-null; apoEâ/âp27Ser10Ala; apolipoprotein E-null p27 Serine-10-Alanine; BM; bone marrow; CKI; cyclin-dependent kinase inhibitor; DMEM; Dulbecco's modified eagle medium; EC(s); endothelial cell(s); ECGS; endothelial cell gr
Liver maturation deficiency in p57Kip2â/â mice occurs in a hepatocytic p57Kip2 expression-independent manner
Keywords: Afp; α-fetoprotein; Bmp; bone morphogenic proteins; C/EBPα; CCAAT/enhancer-binding protein α; CK; cytokeratin; CKI; cyclin-dependent kinase inhibitor; Cyp; cytochrome P450; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; Dlk1; delta-like 1 homol
Molecular cloning and characterization of the β-catenin gene from fine-wool sheep
Keywords: ORF; open reading frame; CDS; coding sequence; RACE; rapid amplification of cDNA ends; GSK3β; glycogen synthase kinase 3β; CKI; casein kinase I; AA; amino acid; APC; adenoma polyposis coli; PP2A; protein phosphatase 2A; LRP; low-density lipoprotein rece
Shikonin induces cell cycle arrest in human gastric cancer (AGS) by early growth response 1 (Egr1)-mediated p21 gene expression
Keywords: CDK; cyclin dependent kinase; ChIP; chromatin immunoprecitiation; CKI; cyclin-dependent kinase; Egr1; early growth response 1; siRNA; small interfering RNA; Anti-proliferation; Cell cycle arrest; Egr1; p21; Shikonin;
Protein degradation during the diatom cell cycle: Annotation and transcriptional analysis of SCF and APC/C ubiquitin ligase genes in Phaeodactylum tricornutum
Keywords: CDK; cyclin dependent kinase; SCF; Skp Cullin F-box; APC/C; anaphase promoting complex/cyclosome; CUL; cullin; CSM; CDH1-specific motif; D-box; destruction box; CKI; CDK inhibitor; RBX; RING box protein; SKP1; S-phase kinase-associated protein 1; CCS52; c
PPARγ1 phosphorylation enhances proliferation and drug resistance in human fibrosarcoma cells
Keywords: PPARγ; peroxisome proliferator-activated receptor γ; PPRE; PPAR-response elements; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; PCNA; proliferating cell nuclear antigen; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
Modelling cell division and endoreduplication in tomato fruit pericarp
Keywords: CDK; cyclin dependent kinase; CKI; cyclin dependent kinase inhibitor; APC/C; anaphase promoting complex; KRP/ICK; Kip-related protein/Interactor of CDKs, family of CKIs; E2F; family of transcription factors; DP; dimerization partner; DEL; dimerization par
Poly(A) polymerase (PAP) diversity in gene expression - Star-PAP vs canonical PAP
Keywords: Poly(A) polymerase (PAP); Canonical PAP; PAP isoforms; PAPα; Star-PAP; PI4,5P2; PIPKIα; CKI; Polyadenylation; Uridylation; 3â²-end processing; Oxidative stress;
Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1
Keywords: Rho GDIα; Rho GDP-dissociation inhibitor α; GFP; green fluorescence protein; BrdU; bromodeoxyuridine; 7-AAD; 7-amino-actinomycin D; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; siRNA; small interfering RNA; Siah1; seven in absen
Novel bioactivity of phosvitin in connective tissue and bone organogenesis revealed by live calvarial bone organ culture models
Keywords: PTH; parathyroid hormone; CKI; casein kinase I; OPN; osteopontin; BSP; bone sialoprotein; ECM; extracellular matrix; Ca-P; calcium phosphate; P-Ser; phosphoserine; P-Thr; phosphothreonine; P-Tyr; phosphotyrosine; mCKII; microsomal casein kinase II; RANKL;
Cell cycle control factors and skeletal development
Keywords: Cell cycle; Transcription factor; Cdk; Cyclin; CKI;
ReviewPP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates
Keywords: CDK; cyclin dependent kinase; CKI; cyclin dependent kinase inhibitor; PP1; protein phosphatase 1; PP2A; protein phosphatase 2A; RB; retinoblastoma; EGF; epidermal growth factor; HEAT; Huntington, elongation factor 3, PR65/A, TOR; GANP; germinal center-ass
Disruptive cell cycle regulation involving epigenetic downregulation of Cdkn2a (p16Ink4a) in early-stage liver tumor-promotion facilitating liver cell regeneration in rats
Keywords: BNF; β-naphthoflavone; Cdc2; cell division cycle 2; Cdc25c; cell division cycle 25 homolog C (S. pombe); Cdk; cyclin-dependent kinase; Chk1; checkpoint kinase 1; CKI; cyclin-dependent kinase inhibitor; DEN; N-diethylnitrosamine; FB; fenbendazole; γH2AX;
Molecular characterization and expression profiles of cdc2 and cyclin B during oogenesis and spermatogenesis in green mud crab (Scylla paramamosain)
Keywords: BCIP; (5-bromo-4-chloro-1H-indol-3-yl) dihydrogen phosphate; BSA; bovine serum albumin; CDC; cell division cycle; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; GSI; gonadosomatic index; GVBD; germinal vesicle breakdown; MPF; matura
Activin A, p15INK4b Signaling, and Cell Competition Promote Stem/Progenitor Cell Repopulation of Livers in Aging Rats
Keywords: p16INK4a; p19ARF; p21/CIP1; Stem Cell Therapy; cdk; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; FLSPC; fetal liver stem/progenitor cell; mRNA; messenger RNA; PH; partial hepatectomy; TGF-β; transforming growth factor-β;
The Physiological Significance of p27KIP1 Expression in Detrusor Function
Keywords: urinary bladder; urinary bladder neck obstruction; cyclin-dependent kinase inhibitor p27; hyperplasia; mice; BOO; bladder outlet obstruction; CDK; cyclin-dependent kinase; CKI; CDK inhibitor; DLPP; detrusor leak point pressure; NFAT; nuclear factor of act
Recent developments in cyclin-dependent kinase biochemical and structural studies
Keywords: CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; T160pCDK2/cyclinA; CDK2 phosphorylated on Thr160 bound to cyclinA; Y15pT160pCDK2/cyclinA; CDK2 phosphorylated on Tyr15 and on Thr160 bound to cyclinA; CBF; cyclin box fold; CDK; Cyclin;
Strategies for the enhancement of recombinant protein production from mammalian cells by growth arrest
Keywords: Controlled proliferation; Hypothermic growth; Sodium butyrate; CHO; Recombinant protein; CDK; CKI
Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats
Keywords: AAF; acetylaminofluorene; ALT; alanine aminotransferase; CdK; cyclin-dependent kinase; CKi; cyclin-dependent kinase inhibitor; CTL; control; CYP; cytochrome p450; DEN; diethylnitrosamine; FAH; foci of altered hepatocytes; GSTp; glutathione S-transferase o
The anti-proliferation mechanism of glucocorticoid mediated by glucocorticoid receptor-regulating gene expression
Keywords: Dex; dexamethasone; GCs; glucocorticoids; GR; glucocorticoid receptor; TGF-β1; transforming growth factor-β1; TβRI; TGF-β receptor type I; TβRII; TGF-β receptor type II; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; RT-PCR; reve
Molecular networks and system-level properties
Keywords: Systems biology; Cell cycle; G1/S transition; Cki; Sic1; Far1; Cln3; CK2; Robustness; Emergent property; Network
Transcriptional control of cell-cycle quiescence during C. elegans development
Keywords: C. elegans; Vulval development; Cell-cycle quiescence; Transcription; FoxB; Ets; Mediator; CKI;
Notch signaling regulates growth and differentiation in the mammalian lens
Keywords: Lens development; Notch signaling; Rbpj; Activated Notch; Growth; Cyclins; CKI
In CK2 inactivated cells the cyclin dependent kinase inhibitor Sic1 is involved in cell-cycle arrest before the onset of S phase
Keywords: Cell cycle; Saccharomyces cerevisiae; Cki; Sic1; CK2; G1/S transition
Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells
Keywords: Cell cycle; Saccharomyces cerevisiae; CK2; Sic1; Cki; 2-D Gel electrophoresis; Mass spectrometry analysis; Co-immunoprecipitation; Phosphorylation; Protein interaction
Regulation of wingless signaling by the CKI family in Drosophila limb development
Keywords: Wg; Wnt; CKI; Kinase; β_catenin; Limb development; Signaling; Cancer;
Activation of the transcription factor NFAT1: concerted or modular regulation?
Keywords: NES; nuclear export signal; NLS; nuclear localisation signal; SP region; serine and proline-rich region; SRR region; serine-rich region; NFAT; nuclear factor of activated T-cells; MAP kinase; mitogen-activated protein kinase; CKI; casein kinase I; GSK3; g
Protein kinases as drug targets in trypanosomes and Leishmania
Keywords: CAK; cdc2-activating kinase; CDK; cyclin-dependent kinase; CKI; casein kinase I; CRK; cdc2-related kinase gene; CRK; cdc2-related kinase protein; ePK; eukaryotic protein kinase; HAT; human African trypanosomiasis; Protein kinase; Cell cycle; Chemotherapy;
Multinuclear giant cell formation is enhanced by down-regulation of Wnt signaling in gastric cancer cell line, AGS
Keywords: APC; adenomatous polyposis coli; CKI; casein kinase I; GSK-3β; glycogen synthase kinase-3β; ICAT; inhibitor of β-catenin; Mab; monoclonal antibody; LiCl; lithium chloride; IF; immunofluorescence; MT; microtubule; AGS cells; Wnt signaling; Giant cell fo