Keywords: CNS، سیستم عصبی مرکزی; PD, Parkinson’s disease; DAergic, dopaminergic; SNpc, substantia nigra pars compacta; DA, dopamine; LB, lewy body; α-syn, alpha synuclein; L-DOPA, levodopa; MAO, monoamine oxidase; CNS, central nervous system; DDS, drug delivery systems; MPs, microparticl
مقالات ISI CNS، سیستم عصبی مرکزی (ترجمه نشده)
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Keywords: CNS، سیستم عصبی مرکزی; Rhamnaceae; Pain; Inflammation; Antinociception; Scutia buxifoliaS. buxifolia, Scutia buxifolia Reissek; SBE, Scutia buxifolia extract; CNS, central nervous system; COX, ciclooxigenase; PGs, prostaglandins; LOD, limit of detection; LOQ, limit of quantific
Keywords: CNS، سیستم عصبی مرکزی; CNS, central nervous system; COX, cyclooxygenase; CSF, cerebrospinal fluid; EAAT2, excitatory amino acid transporter 2; GWAS, genome-wide association study; HLA, human leukocyte antigen; IFN, interferon; IL, interleukin; KYP, kynurenine pathway; LPS, lipo
Keywords: CNS، سیستم عصبی مرکزی; hAFS, cellshuman amniotic fluid-derived cells; hESCs, human embryonic stem cells; SVZ, subventrical zone; EBs, embryoid bodies; CNS, central nervous system; iPSCs, induced pluripotent stem cells; GSK3, Glycogen synthase kinase 3; NPCs, neural precursor/pr
Keywords: CNS، سیستم عصبی مرکزی; Type 1 diabetes; Glucose; Vagotomy; Sympathectomy; Brown adipose tissue; Streptozotocin6OHDA, 6-hydroxydopamine; ANS, autonomic nervous system; BAT, brown adipose tissue; CNS, central nervous system; CCK, cholecystokinin; iBAT, interscapular BAT; STZ, str
Keywords: CNS، سیستم عصبی مرکزی; ANS, autonomic nervous system; CNS, central nervous system; DβH, dopamine β hydroxylase; PBS, phosphate buffered saline; SD, Sprague-Dawley; SHR, spontaneously hypertensive rats; TH, tyrosine hydroxylase; WKY, Wistar-KyotoMicroglia; Iba1; Tyrosine hydroxy
Keywords: CNS، سیستم عصبی مرکزی; Autophagy; Optic nerve; Axonal degeneration; Retinal ganglion cells; Glaucoma; Optic atrophyAAV, adeno-associated viral vector; ADOA, autosomal dominant optic atrophy; CMA, chaperone-mediated autophagy; CNS, central nervous system; IOP, intraocular pressu
Keywords: CNS، سیستم عصبی مرکزی; AP, antipsychotic; CD, cluster of differentiation; CNS, central nervous system; COMT, catechol-O-methyltransferase; COX, cyclooxygenase; CSF, cerebrospinal fluid; CSF2RA, colony stimulator factor receptor 2 alpha; DISC, disrupted in schizophrenia; GWAS, g
Keywords: CNS، سیستم عصبی مرکزی; Estrogen; Estrogen receptor alpha; MAO; P38; Parkinson's diseaseAD, Alzheimer's disease; CNS, central nervous system; DA, dopamine acid; DAT, dopamine transporter; DOPAC, 3,4-dihydroxyphenylacetic acid; GFAP, glial fibrillary acidic protein; KO, knockout;
Keywords: CNS، سیستم عصبی مرکزی; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CNS, central nervous system; Cu, Copper; kgBWt, kg Body Weight; LEC, Long Evans Cinnamon; MRI, magnetic resonance imaging; WD, Wilson diseaseCopper; Liver; Kidney; B
Keywords: CNS، سیستم عصبی مرکزی; BMDMs, bone marrow-derived macrophages; Ca2+, calcium; CNS, central nervous system; EAE, experimental autoimmune encephalomyelitis; FACS, fluorescence-activated cell sorting; IFN, interferon; iNOS, inducible nitric oxide synthase; LPS, lipopolysaccharide;
Keywords: CNS، سیستم عصبی مرکزی; AD, Alzheimer’s disease; BrdU, 5-bromo-2′-deoxyuridine; CAT, catalase; CCK-8, cell counting Kit-8; CNS, central nervous system; DCF, dichlorofluorescin; DCF-DA, 2′,7′-dichlorofluorescin diacetate; DMEM, Dulbecco’s modified Eagle’s medium; FITC, fluorescei
Keywords: CNS، سیستم عصبی مرکزی; BLBP, brain lipid-binding protein; BM, basement membrane; BSA, bovine serum albumin; CNS, central nervous system; CP, cortical plate; DAPI, 4′,6-diamidino-2-phenylindole; GFAP, glial fibrillary acidic protein; IUE, in utero electroporation; IZ, intermedia
Keywords: CNS، سیستم عصبی مرکزی; TLE, temporal lobe epilepsy; CNS, central nervous system; OPC, oligodendrocyte precursor cell; AEDs, anti-epileptic drugs; SC, status convulsion; NG2, chondroitin sulfate proteoglycan; PDGFR-α, platelet-derived growth factor receptor α; SRS, spontaneous r
Selective 5-HT2C receptor agonists: Design and synthesis of pyridazine-fused azepines
Keywords: CNS، سیستم عصبی مرکزی; ADME, absorption, distribution, metabolism, and excretion; CHO, Chinese hamster ovary; CNS, central nervous system; ER, efflux ratio; FLIPR, fluorescence imaging plate reader; HLM, human liver microsomes; MDCK, Madin–Darby Canine Kidney cell line; MDR-1,
Alterations of miRNAs reveal a dysregulated molecular regulatory network in Parkinson’s disease striatum
Keywords: CNS، سیستم عصبی مرکزی; PD, Parkinson’s disease; CNS, central nervous system; DA, dopamine; miRNA, microRNA; mRNA, messenger RNA; RIN, RNA integrity number; L-dopa, levodopa; LID, L-dopa induced dyskinesia; DE, differentially expressed; LTP, long term potentiation; TNFSF13B, TNF
Mutation of the key residue for extraribosomal function of ribosomal protein S19 cause increased grooming behaviors in mice
Keywords: CNS، سیستم عصبی مرکزی; ANOVA, analysis of variance; CNS, central nervous system; RP S19, ribosomal protein S19; KI, knock-in; WT, wild-type; Gln, glutamine; Glu, glutamic acid; C5a, complement 5aAnxiety-like behavior; Complement system; Extraribosomal function; Fear memory; Gro
Aggregatibacter aphrophilus ventriculitis following C1-C2 transarticular screw fixation
Keywords: CNS، سیستم عصبی مرکزی; CNS, central nervous system; CSF, cerebrospinal fluid; IE, infective endocarditis; RA, rheumatoid arthritis; NSAIDS, non-steroidal anti-inflammatory drugs; MRI, magnetic resonance imaging; NECCT, non-enhanced cranial computed tomography; GCS, Glasgow Coma
Lower Urinary Tract Symptoms and Risk of Nonspine Fractures among Older Community Dwelling U.S. Men
Keywords: CNS، سیستم عصبی مرکزی; lower urinary tract symptoms; male; aged; fractures, boneAUA-SI, American Urological Association Symptom Index; BMD, bone mineral density; BPH, benign prostatic hyperplasia; CNS, central nervous system; LUTS, lower urinary tract symptoms
CD4+HLA-G+ regulatory T cells: Molecular signature and pathophysiological relevance
Keywords: CNS، سیستم عصبی مرکزی; cAMP, cyclic adenosine monophosphate; CCR5, chemokine (C–C motif) receptor 5; CNS, central nervous system; FoxP3, forkhead box protein P3; GvHD, graft-versus-host disease; MS, multiple sclerosis; TCR, T-cell receptor; Teff, effector T cells; tTreg, thymus
The immunomodulatory effect of laquinimod in CNS autoimmunity is mediated by the aryl hydrocarbon receptor
Keywords: CNS، سیستم عصبی مرکزی; AhR, aryl hydrocarbon receptor; APC, antigen-presenting cell; BDNF, brain-derived neurotrophic factor; CNS, central nervous system; DC, dendritic cell; EAE, experimental autoimmune encephalomyelitis; KO, knockout; MOG, myelin oligodendrocyte glycoprotein;
In-vivo edema inhibition of Hyoscyamus albus antioxidant extracts rich in calystegines
Keywords: CNS، سیستم عصبی مرکزی; AAPH, 2,2′-Azobis(2-amidinopropane) dihydrochloride; ABTS, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); BHA, butylhydroxyanisol; BHT, butylhydroxytoluene; CNS, central nervous system; DPPH, 1,1-diphenyl-2-picrylhydrazyl; DW, Dry Weight; GC–MS,
Preferred transduction with AAV8 and AAV9 via thalamic administration in the MPS IIIB model: A comparison of four rAAV serotypes
Keywords: CNS، سیستم عصبی مرکزی; MPS IIIB; Mucopolysaccharidosis type III B; Gene therapy; Adeno-associated virus; AAV; Lysosomal storage diseaserAAV, recombinant adeno-associated virus; ANOVA, analysis of variance; MPS IIIB, mucopolysaccharidosis type III B; CNS, central nervous system;
Prospective study on the chemokine CXCL13 in neuroborreliosis and other aseptic neuroinfections
Keywords: CNS، سیستم عصبی مرکزی; AI, antibody index; APRIL, A proliferation inducing ligand; BAFF, B-cell activating factor; CNS, central nervous system; CC, chemokines motif C–C; CR, Czech Republic; CSF, cerebrospinal fluid; CXC, chemokines motif C–X–C; DNA, deoxyribonucleic acid; ELISA
Anti-IL-17A blocking antibody reduces cyclosporin A-induced relapse in experimental autoimmune encephalomyelitis mice
Keywords: CNS، سیستم عصبی مرکزی; CNS, central nervous system; CsA, cyclosporine A; EAE, Experimental autoimmune encephalomyelitis; IL, interleukin; MOG, myelin oligodendrocyte glycoprotein; MS, multiple sclerosis; NFAT, Nuclear factor of activated T-cells; PLP, proteolipid protein; ROR-γ
Differential A-to-I RNA editing of the serotonin-2C receptor G-protein-coupled, HTR2C, in porcine brain tissues
Keywords: CNS، سیستم عصبی مرکزی; Ageing; Brain; Phylogenetic conservation; Pig; RNA editingADAR, adenosine deaminases acting on RNA; CBE, cerebellum; CNS, central nervous system; FCO, frontal cortex; FPKM, fragments per kilobase of exon per million fragments mapped; HYPO, hypothalamus; M
Agatoxin-like peptides in the neuroendocrine system of the honey bee and other insects
Keywords: CNS، سیستم عصبی مرکزی; AKH, adipokinetic hormone; ALP, agatoxin-like peptide; CAM, carbamidomethylation; CC, corpora cardiaca; CDS, coding DNA sequence; CNS, central nervous system; CRF-DH, corticotropin-releasing factor-like diuretic hormone; PP, precursor peptideAgatoxin; Adi
In vitro evaluation of inorganic and methyl mercury mediated cytotoxic effect on neural cells derived from different animal species
Keywords: CNS، سیستم عصبی مرکزی; 1640, RPIM-1640 medium; BSA, bovine serum albumin; BV-2, mouse microglia cells; CB, Coomassie blue; CHME-5, transformed human microglia cells; CNS, central nervous system; DMEM, Dulbecco's Modified Eagle's Medium; DMSO, dimethyl sulfoxide; FBS, fetal bovi
Spatio-temporal regulations and functions of neuronal alternative RNA splicing in developing and adult brains
Keywords: CNS، سیستم عصبی مرکزی; AMPAR, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; ASD, autism-spectrum disorder; AS4, alternatively spliced segment 4; CaMKIV, Ca2+/calmodulin-dependent kinase IV; CCK, cholecystokinin; CNS, central nervous system; DSCAM, Down syndrome
Design and comparative anticonvulsant activity assessment of CNS-active alkyl-carbamoyl imidazole derivatives
Keywords: CNS، سیستم عصبی مرکزی; CNS, central nervous system; AED, antiepileptic drug; NIH, National Institute of Health; SAR, structure–activity relationship; MES, maximal electroshock seizure; scMet, subcutaneous metrazol; ED50, dose effective in 50% of test subjects; TD50, dose neurot
Structure–activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport
Keywords: CNS، سیستم عصبی مرکزی; AP, apical; BL, basolateral; CNS, central nervous system; DBHs, dibenzoylhydrazines; DDI, drug–drug interactions; ESI, electrospray ionization; esp, electrostatic potential; FBS, fetal bovine serum; GA, Genetic Algorithm; HBSS, Hank’s balanced salt soluti
Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action
Keywords: CNS، سیستم عصبی مرکزی; CA, carbonic anhydrase; CNS, central nervous system; GABA, gamma-aminobutyric acidCarbonic anhydrase; Sulfamides; Docking; Epilepsy; Sodium cyclamate
Evidence that activation of nuclear peroxisome proliferator-activated receptor alpha (PPARα) modulates sleep homeostasis in rats
Keywords: CNS، سیستم عصبی مرکزی; 5-HT, serotonin; AcbC, nucleus accumbens; AD, adenosine; CNS, central nervous system; DA, dopamine; EEG, electroencephalogram; EMG, electromyogram; HPLC, high-performance liquid chromatography; NE, norepinephrine; OEA, oleoylethanolamide; PPARα, peroxisom
Nicotinic receptor blockade decreases fos immunoreactivity within orexin/hypocretin-expressing neurons of nicotine-exposed rats
Keywords: CNS، سیستم عصبی مرکزی; CNS, central nervous system; DA, dopamine; ir, immunoreactivity; nAChR, nicotinic acetylcholine receptor; NAcc, nucleus accumbens; OxA, orexin-A; Ox1R, orexin receptor subtype 1; Ox2R, orexin receptor subtype 2; PBS, phosphate-buffered saline; VTA, ventra
Alcohol intake alters immune responses and promotes CNS viral persistence in mice
Keywords: CNS، سیستم عصبی مرکزی; AST, aspartate aminotransferase; BBB, blood brain barrier; CNS, central nervous system; EtOH, ethanol; HCV, hepatitis C virus; LCMV, lymphocytic choriomeningitis virus; PFU, plaque forming unitsBlood brain barrier; Ethanol; Hepatitis C virus; Lymphocytic
Effects of peripherally administered urotensin II and arginine vasotocin on the QT interval of the electrocardiogram in trout
Keywords: CNS، سیستم عصبی مرکزی; ANS, autonomic nervous system; AVT, arginine vasotocin; CNS, central nervous system; ECG, electrocardiogram; IA, intra-arterial; PDA, dorsal aortic blood pressure; PQ, PQ interval of the ECG; QRS, QRS interval of the ECG; QT, QT interval of the ECG; QTc,
Estrogen receptors modulate striatal metabotropic receptor type 5 in intact and MPTP male mice model of Parkinson’s disease
Keywords: CNS، سیستم عصبی مرکزی; A, adenosine; DA, dopamine; CNS, central nervous system; CREB, cAMP response element-binding protein; DAT, dopamine transporter; ERK, extracellular signal-regulated kinase; ER, estrogen receptor; ERKO, estrogen receptor knock out; L-DOPA, levodopa; MAPK,
Clinicopathological, Radiological, and Genetic Analyses of Cerebellar Gangliogliomas with Long-Term Survival
Keywords: CNS، سیستم عصبی مرکزی; BRAF V600E mutation; Cerebellum; Ganglioglioma; Isocitrate dehydrogenase 1 mutation; Pediatric; MGMT promoter methylation; PrognosisBRAFV600E, V-RAF murine sarcoma viral oncogene homolog B V600E; CNS, Central nervous system; IDH-1, Isocitrate dehydrogenas
Activation of the adenosine A2A receptor exacerbates experimental autoimmune neuritis in Lewis rats in association with enhanced humoral immunity
Keywords: CNS، سیستم عصبی مرکزی; A2AR, A2A receptor; EAN, experimental autoimmune neuritis; Treg, regulatory T cell; Tfh, T follicular helper cell; Teff, effector T cell; GBS, Guillain–Barré syndrome; PNS, peripheral nervous system; CNS, central nervous system; EAE, experimental autoimmu
Toll-like receptor (TLR)7 and TLR9 agonists enhance interferon (IFN) beta-1a's immunoregulatory effects on B cells in patients with relapsing-remitting multiple sclerosis (RRMS)
Keywords: CNS، سیستم عصبی مرکزی; TLR, toll-like receptor; IFN, interferon; RRMS, relapsing-remitting multiple sclerosis; IFNAR, IFN receptor; HC, healthy control; LOX, loxorubin; CNS, central nervous system; EAE, experimental autoimmune encephalomyelitis; Treg, T regulatory cells; Breg,
Early and late outcomes of repaired acute DeBakey type I aortic dissection after graft replacement
Keywords: CNS، سیستم عصبی مرکزی; aortic dissection; total arch replacement; long term resultADIAD, acute DeBakey type I aortic dissection; CI, confidence interval; CNS, central nervous system; CT, computed tomography; GRF, gelatin-resorcin-formalin; HR, hazard ratio; TAR, total arch repl
Identifying microRNAs related to Alzheimer's disease from differential methylation signatures
Keywords: CNS، سیستم عصبی مرکزی; miRNA, microRNA; AD, Alzheimer's disease; RISC, RNA induced silencing complex; CNS, central nervous system; SP, senile plaques; Aß, amyloid-beta; NFT, neurofibrillary tangles; GWAS, genome-wide association studies; EWAS, epigenome-wide association studies
Deletion of Atf6α enhances kainate-induced neuronal death in mice
Keywords: CNS، سیستم عصبی مرکزی; ATF6α; Kainate; Neuronal death; UPR; Ca2+ATF6α, activating transcription factor 6α; CNS, central nervous system; CHOP, C/EBP homologous protein; DAPI, 4′,6-diamidino-2-phenylindole; ER, endoplasmic reticulum; FJC, Fluoro-Jade C; GFAP, glial fibrillary aci
N-methyl-N-nitrosourea-induced schwannomas in male Sprague-Dawley rats with a literature review of inducible and spontaneous lesions
Keywords: CNS، سیستم عصبی مرکزی; SMA, α smooth muscle actin; CNS, central nervous system; ENU, N-ethyl-N-nitrosourea; GLP, good laboratory practice; H&E, hematoxylin and eosin; INHAND, International Harmonization of Nomenclature and Diagnostic Criteria; NIEHS, National Institute of Envir
Transdermal immunotherapy: Past, present and future
Keywords: CNS، سیستم عصبی مرکزی; AD, atopic dermatitis; AIT, allergen immunotherapy; CIA, collagen-induced arthritis; CNS, central nervous system; COLL II, type II collagen; CpG, unmethylated cytidine–guanosine dinucleotides; DC, dermal dendritic cells; DNFB, 2,4-dinitrofluorobenzene; EA
Increased apoptosis and abnormal visual behavior by histone modifications with exposure to para-xylene in developing Xenopus
Keywords: CNS، سیستم عصبی مرکزی; AI, avoidance index; CNS, central nervous system; FETAX, frog embryo teratogenesis assay-Xenopus; GA, d-glucuronolactone; HDACs, histone deacetylases; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; PX, para-xyleneXenopus; para-xylene; apoptosi
Intranasal insulin protects against substantia nigra dopaminergic neuronal loss and alleviates motor deficits induced by 6-OHDA in rats
Keywords: CNS، سیستم عصبی مرکزی; 6-OHDA, 6-hydroxydopamine; CNS, central nervous system; CSF, cerebrospinal fluid; IGF-1, insulin-like growth factor-1; IR, insulin receptor; METH, methamphetamine; NTFs, neurotrophic factors; PD, Parkinson’s disease; PFA, paraformaldehyde; SN, substantia
Kinetics modeling and occupancy studies of a novel C-11 PET tracer for VAChT in nonhuman primates
Keywords: CNS، سیستم عصبی مرکزی; ACh, acetylcholine; AChE, acetylcholinesterase; AD, Alzheimer's disease; AIR, automated image registration; BPND, binding potential (non-displaceable); ChAT, choline acetyltransferase; CNS, central nervous system; CR, radiotracer concentration in the refe
Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study
Keywords: CNS، سیستم عصبی مرکزی; DM, type 2 diabetes; GLP-1, glucagon-like peptide-1; fMRI, functional magnetic resonance imaging; CNS, central nervous system; DLPFC, dorsolateral prefrontal cortex; pre-SMA, pre-supplementary motor area; BMI, body mass index; BIDMC, Beth Israel Deaconess
Involvement of MEK-ERK1-2 pathway in the anti-oxidant response in C6 glioma cells after diesel exhaust particles exposure
Keywords: CNS، سیستم عصبی مرکزی; UFPs, ultrafine particles; CNS, central nervous system; DEP, diesel exhaust particles; PAHs, polycyclic aromatic hydrocarbons; ROS, reactive oxygen species; Nrf2, nuclear factor (erythroid-derived 2)-like 2; ARE, antioxidant responsive elements; HO-1, hem