Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ATF, Activating Transcription Factor; CaMK, Ca2+/Calmodulin-dependent protein kinase; CAT, Catalase; CREB, cAMP Response Element-binding Protein; EE, endurance exercise; ER α, Estrogen Receptor α; FOXO, Fork Head Box; GLUT-4, Glucose Transporter-4; GPX, g
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Keywords: CREB، cAMP پروتئین اتصال دهنده المان; AMPK, AMP-activated protein kinase; ANOVA, analysis of variance; AUC, area under the curve; CREB, cAMP response element-binding protein; DPP4, dipeptidyl peptidase 4; eWAT, epididymal white adipose tissue; FOXO1, forkhead box protein O1; GIP, glucose-depe
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; AD, Alzheimer's disease; Bcl-2, B-cell lymphoma 2 protein; BDNF, brain-derived neurotrophic factor; CNS, central nervous system; COMT, catechol-O-methyltransferase; CREB, cAMP response element-binding protein; DAOA, gene for d-amino acid oxidase activator
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; 5-Aza, 5-Aza-2′-deoxycytidine; cFLIP, cellular FLICE inhibitory protein; CREB, cAMP response element-binding protein; DEDs, death effector domains; DISC, death-inducing signaling complex; FADD, Fas-Associated protein with Death Domain; HDAc, histone deace
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; Akt, also called protein kinase B (PKB); CaMKII and CaMKIV, Ca2 +/calmodulin-dependent protein kinase II and IV; CNS, central nervous system; CREB, cAMP response element-binding protein; (PhSe)2, diphenyldiselenide; LTM, long-term memory; MAPK, mitogen-ac
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; BDNF, brain derived neurotrophic factor; CUMS, chronic unpredictable mild stress; CREB, cAMP response element-binding protein; ERK, extracellular signal-regulated kinase; HPA, hypothalamic–pituitary–adrenal; RT-PCR, reverse transcription-polymerase chain
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; Bdnf, brain-derived neurotrophic factor; BPD, bipolar disorder; CBP, CREB-binding protein; CHD5, chromodomain helicase DNA-binding protein 5; ChIP-Seq, chromatin immunoprecipitation-sequencing; CREB, cAMP response element-binding protein; CUMS, chronic ul
Distinct effect of CacyBP/SIP on the ERK1/2-CREB-BDNF pathway in undifferentiated and differentiated neuroblastoma NB2a cells
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; BDNF; CacyBP/SIP; Cell differentiation; CREB; ERK1/2; NB2a cellsBDNF, brain-derived neurotrophic factor; CREB, cAMP response element-binding protein; DTT, dithiothreitol; ERK1/2, extracellular signal regulated kinases 1 and 2; PAGE, polyacrylamide gel ele
Andrographolide inhibits adipogenesis of 3T3-L1 cells by suppressing C/EBPβ expression and activation
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; CDK, cyclin-dependent kinase; CREB, cAMP response element-binding protein; C/EBP, CCAAT/enhancer-binding protein; EMSA, electrophoretic mobility shift assay; ERK, extracellular signal-regulated kinases; FAS, fatty acid synthase; GSK, glycogen synthase kin
Clivorine, an otonecine pyrrolizidine alkaloid from Ligularia species, impairs neuronal differentiation via NGF-induced signaling pathway in cultured PC12 cells
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; Clivorine; Ligularia species; Pyrrolizidine alkaloids; Neurotoxicity; Neuronal differentiation; Protein kinase BAkt, protein kinase B; CREB, cAMP response element-binding protein; DHP, dehydro-PA; Erk, extracellular signal-regulated kinase; GAPDH, glycera
Estrogen receptors modulate striatal metabotropic receptor type 5 in intact and MPTP male mice model of Parkinson’s disease
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; A, adenosine; DA, dopamine; CNS, central nervous system; CREB, cAMP response element-binding protein; DAT, dopamine transporter; ERK, extracellular signal-regulated kinase; ER, estrogen receptor; ERKO, estrogen receptor knock out; L-DOPA, levodopa; MAPK,
Prostaglandin E2 promotes M2 polarization of macrophages via a cAMP/CREB signaling pathway and deactivates granulocytes in teleost fish
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; Prostaglandins; Macrophages; Acidophilic granulocytes; Polarization; Teleosts; EvolutionAGs, acidophilic granulocytes; cAMP, cyclic adenosine monophosphate; COX, cyclooxygenase; CREB, cAMP response element-binding protein; HPGD, 15 hydroxy-prostaglandin-d
Status epilepticus stimulates NDEL1 expression via the CREB/CRE pathway in the adult mouse brain
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ChIP, chromatin immunoprecipitation; CREB, cAMP response element-binding protein; DAB, diaminobenzidine; DISC1, disrupted in schizophrenia 1; GCL, granule cell layer; GFP, green fluorescent protein; GFAP, glial fibrillary acidic protein; Hil, hilus; LIS1,
Antidepressant therapies inhibit inflammation and microglial M1-polarization
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; 5HT, serotonin; BH4, tetrahydrobiopterin; CBP, CREB-binding protein; CREB, cAMP response element-binding protein; DA, dopamine; ECT, electroconvulsive shock therapy; GR, glucocorticoid-receptor; GSK3 β, glycogen synthase kinase-3β; HAT, histone acetyltran
Repeated forced swim stress affects the expression of pCREB and ΔFosB and the acetylation of histone H3 in the rostral ventromedial medulla and locus coeruleus
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ABC, avidin-biotin-peroxidase complex; BSA, bovine serum albumin; CBP, CREB-binding protein; CCK, cholecystokinin; CFA, complete Freund’s adjuvant; CREB, cAMP response element-binding protein; FS, forced swim stress; GAD, glutamic acid decarboxylase; HAT,
Erk-Creb pathway suppresses glutathione-S-transferase pi expression under basal and oxidative stress conditions in zebrafish embryos
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; Ahr, aryl hydrocarbon receptor; Akt, protein kinase B; AOE, antioxidant enzyme; AP-1, activator protein 1; cAMP, cyclic adenosine monophosphate; cat, catalase; CRE, cAMP response element; Creb, cAMP response element-binding protein; cyp1a, cytochrome P450
d-Serine in the nucleus accumbens region modulates behavioral sensitization and extinction of conditioned place preference
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; 7-CIKY, 7-chlorokynurenate; aCSF, artificial cerebrospinal fluid; BCM, Bienenstock-Cooper-Munro; CAMKII, calcium/calmodulin-dependent kinases II; CPP, the conditioned place preference; CREB, cAMP response element-binding protein; DAAO, D-amino acid oxidas
Determination of a novel phosphodiesterase-4 inhibitor chlorbipram in mouse plasma and brain by UFLC–MS/MS: Application in pharmacokinetic studies after intravenous administration
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; PDE4, phosphodiesterase-4; UFLC–MS/MS, ultra-fast liquid chromatography-tandem mass spectrometry; MRM, multiple reaction monitoring; ESI, electrospray ionization; IS, internal standard; cAMP, cyclic AMP; CREB, cAMP response element-binding protein; BDNF,
Piperine, a component of black pepper, decreases eugenol-induced cAMP and calcium levels in non-chemosensory 3T3-L1 cells
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; CREB, cAMP response element-binding protein; OST, odorant-induced signal transduction; PNF, Piper nigrum fructuscAMP; Black pepper; Olfactory; Piper nigrum; Piperine; 3T3-L1
Clozapine induces chloride channel-4 expression through PKA activation and modulates CDK5 expression in SH-SY5Y and U87 cells
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; CDK5, cyclin-dependent kinase 5; CLC-4, chloride channel-4; CREB, cAMP response element-binding protein; NGF, nerve growth factor; PKA, protein kinase AChloride channel-4; Clozapine; Cyclin-dependent kinase 5; SH-SY5Y; U87
Cloning and characterization of the proximal promoter region of rainbow trout (Oncorhynchus mykiss) interleukin-6 gene
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; Cytokines; IL6; Luciferase reporter assay; NF-κB p50; TeleostAa, amino acids; CEBP, CCAAT/enhancer-binding protein; CREB, cAMP response element-binding protein; GFP, green fluorescent protein; HEK, human embryonic kidney; LUC, luciferase; MCS, multiple cl
Resveratrol abrogates lipopolysaccharide-induced depressive-like behavior, neuroinflammatory response, and CREB/BDNF signaling in mice
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; CREB, cAMP response element-binding protein; FST, forced swimming test; IL, interleukin; LPS, lipopolysaccharide; PFC, prefrontal cortex; TNF-α, tumor necrosis factor-α; TST, tail suspension testResveratrol; Lipopolysaccharide; Depression; Pro-inflammator
Danggui-Jakyak-San enhances hippocampal long-term potentiation through the ERK/CREB/BDNF cascade
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; DJS, Danggui-Jakyak-San; ERK1/2, extracellular signal-regulated kinase 1/2; CREB, cAMP response element-binding protein; BDNF, brain-derived neurotropic factor; LTP, long-term potentiation; LTD, long-term depression; fEPSP, field excitatory postsynaptic p
Intramitochondrial adenylyl cyclase controls the turnover of nuclear-encoded subunits and activity of mammalian complex I of the respiratory chain
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; 8-Br-cAMP, 8-bromoadenosine 3′,5′-cyclic monophosphate; CAI, carbonic anhydrase inhibitor; CREB, cAMP response element-binding protein; DMEM, Dulbecco's modified Eagle's medium; FBS, fetal bovine serum; tmAC, transmembrane adenylyl cyclase; mtDNA, mitocho
Working memory training triggers delayed chromatin remodeling in the mouse corticostriatothalamic circuit
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; cAMP, cyclic adenosine monophosphate; c-fos, FBJ murine osteosarcoma viral oncogene homologue; cGMP, cyclic guanosine monophosphate; CREB, cAMP response element-binding protein; D1-R, dopamine receptor D1; DLSt, dorsolateral striatum; DMSt, dorsomedial st
Functional sequence variants within the SIRT1 gene promoter in indirect inguinal hernia
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; SIRT1, Sirtuin 1; DSVs, DNA sequence variants; IIH, indirect inguinal hernia; ATF4, activating transcription factor 4; CREB, cAMP response element-binding protein; C/EBP, CCAAT/enhancer binding protein alpha; FOXO3, forkhead box transcription factor O3; H
Rutin activates the MAPK pathway and BDNF gene expression on beta-amyloid induced neurotoxicity in rats
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; Aβ, β-amyloid; AD, Alzheimer's disease; Akt/PKB, protein kinase B; Arc, activity-regulated cytoskeleton-associated protein; BDNF, brain-derived neurotrophic factor; CAT, catalase; CREB, cAMP response element-binding protein; GSH, glutathione; GPx, glutath
New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; AC-5/8, adenylyl cyclase isoforms 5 or 8; ddAdo, 2′,5′-dideoxyadenosine; CA, carbonic anhydrase; cAMP, adenosine-3′,5′-cyclic monophosphate; CREB, cAMP response element-binding protein; Epac1/2, exchange proteins activated by cyclic AMP isoforms 1/2; GIP,
Construction and expression of lentiviral vectors encoding recombinant mouse CREBZF in NIH 3T3 cells
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ATF, activating transcription factor; b-ZIP, basic region-leucine zipper; CREB, cAMP response element-binding protein; CREBH, cAMP responsive element-binding protein H; dsRNA, double-stranded RNA; ERRα, estrogen receptor-related receptor; HCF-1, related h
Dynorphin up-regulation in the dentate granule cell mossy fiber pathway following chronic inhibition of GluN2B-containing NMDAR is associated with increased CREB (Ser 133) phosphorylation, but is independent of BDNF/TrkB signaling pathways
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ABC, avidin–biotin–peroxidase complex; APV, D-(−)-2-amino-5-phosphonopentanoic acid; BCA, bicinchoninic acid; BDNF, brain-derived neurotrophic factor; BSA, bovine serum albumin; CREB, cAMP response element-binding protein; DAB, 3,3′-diaminobenzidine; DMSO
Maternal micronutrient imbalance alters gene expression of BDNF, NGF, TrkB and CREB in the offspring brain at an adult age
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; BDNF, brain derived neurotrophic factor; CREB, cAMP response element-binding protein; DAG, diacylglycerol; DHA, docosahexaenoic acid; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; IP3, inositol 1,4,5-trisphosphate; MAPK, mitogen activated protein kinas
Neocortical pCREB and BDNF expression under different modes of hypobaric hypoxia: Role in brain hypoxic tolerance in rats
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; CREB, cAMP response element-binding protein; BDNF, brain-derived neurotrophic factor; SH, severe hypoxia; PC, preconditioningHypobaric hypoxia; Preconditioning; Hypoxic tolerance; Brain; pCREB; BDNF expression
Two natural products, trans-phytol and (22E)-ergosta-6,9,22-triene-3β,5α,8α-triol, inhibit the biosynthesis of estrogen in human ovarian granulosa cells by aromatase (CYP19)
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; cAMP, intracellular cylic AMP; CREB, cAMP response element-binding protein; MAPK, mitogen-activated protein kinase; PI3K, phosphoinositide 3-kinase; PKA, protein kinase A; FSH, follicle-stimulating hormone; PGE2, prostaglandin E2; ELISA, enzyme-linked imm
TSH signaling pathways that regulate MCP-1 in human differentiated adipocytes
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; BSA, bovine serum albumin; CHO, Chinese hamster ovarian; CREB, cAMP response element-binding protein; DMEM, Modified Eagle’s Medium; DPI, diphenyleneiodonium; FBS, fetal bovine serum; FFA, free fatty acids; GPCR, G protein-coupled receptor; IκB, inhibitor
Role of astrocytes in the neuroprotective actions of 17β-estradiol and selective estrogen receptor modulators
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ApoE, apolipoprotein E; BDNF, brain derived neurotrophic factor; CREB, cAMP response element-binding protein; DMT, dimethoate; DPN, diarylpropionitrile (2,3-bis(4-Hydroxyphenyl)-propionitrile est
Creb is modulated in the mouse superior colliculus in developmental and experimentally-induced models of plasticity
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; CREB, cAMP response element-binding protein; RGCs, retinal ganglion cells; dLGN, dorso-lateral geniculate nucleus; SC, superior colliculus; CRE, cAMP response element; P, postnatal day; EDTA, ethylenediaminetetraacetic acid; NaF, sodium fluoride; PMSF, ph
Kami-ondam-tang, a traditional herbal prescription, attenuates the prepulse inhibition deficits and cognitive impairments induced by MK-801 in mice
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ANOVA, Analysis of variance; ASR, Acoustic startle response; BDNF, Brain-derived neurotrophic factor; CREB, cAMP response element-binding protein; ERK, Extracellular signal-regulated kinase; GSK-3β, Glycogen synthase kinase-3β; KODT, Kami-ondam-tang; MK-8
Regulation of mitochondrial biogenesis and PGC-1α under cellular stress
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; AICAR, 5-amino-1-β-d-ribofuranosyl-imidazole-4-carboxamide; AKT, protein kinase B (PKB); AMPK, AMP-activated protein kinase; CO, carbon monoxide; CR, caloric restriction; CREB, cAMP response element-binding protein; DNMT3B, DNA methyltransferase 3b; ERRα,
Induction of neurite outgrowth in PC12 cells by artemisinin through activation of ERK and p38 MAPK signaling pathways
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; cAMP, cyclic AMP; CREB, cAMP response element-binding protein; dbcAMP, dibutyryl cAMP; ERK, extracellular signal-regulated kinase; JNK, c-Jun N-terminal kinase; MAPK, mitogen-activated protein kinase; MTT, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetr
Dynamic plasticity: The role of glucocorticoids, brain-derived neurotrophic factor and other trophic factors
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ACTH, adrenocorticotropic hormone; BDNF, brain-derived neurotrophic factor; BLA, basolateral amygdala; CA, cornu ammonis; CE, central nucleus; CORT, corticosterone; CREB, cAMP response element-binding protein; CRH, corticotrophin-releasing hormone; ERK, e
Mechanisms underlying the interactions between rapid estrogenic and BDNF control of synaptic connectivity
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; AD, Alzheimer’s disease; APP, amyloid precursor protein; BDNF, brain-derived neurotrophic factor; CaMKK, calmodulin-dependent protein kinase; CP-AMPAR, calcium permeable AMPA receptors; CREB, cAMP response element-binding protein; ER, oestrogen receptor;
Remodeling of axo-spinous synapses in the pathophysiology and treatment of depression
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ACd, dorsal anterior cingulate; BD, bipolar disorder; BDNF, brain-derived neurotrophic factor; CREB, cAMP response element-binding protein; CRS, chronic restraint stress; CUS, chronic unpredictable stress; ECS, electroconvulsive seizure; ERK, extracellula
Cadmium activates extracellular signal-regulated kinase 5 in HK-2 human renal proximal tubular cells
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ATF-1, activating transcription factor-1; CdCl2, cadmium chloride; CREB, cAMP response element-binding protein; DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; M
Estrogen and the regulation of mitochondrial structure and function in the brain
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ARKO, aromatase-knockout mice; CamK, calcium-dependent calmodulin kinase; cAMP, cyclic adenosine monophosphate; CGSD, combined glucose-serum deprivation; CNS, central nervous system; COX, cytochrome c oxidase; CREB, cAMP response element-binding protein;
Cannabinoids and monoamine neurotransmission with focus on monoamine oxidase
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; AEA, anandamide; 2-AG, 2-arachidonoylglycerol; BDNF, brain-derived neurotrophic factor; CNS, central nervous system; CREB, cAMP response element-binding protein; GABA, γ-aminobutyric acid; GPCR, G protein-coupled receptor; HU-210, 11-hydroxy-Δ8-THC-dimeth
Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; AD, Alzheimer's disease; B12H, bis(12)-hupyridone; CREB, cAMP response element-binding protein; dbcAMP, dibutyryl cAMP; ERK, extracellular signal-regulated kinase; HA, huperzine A; NGF, nerve growth factor; MEK, mitogen-activated protein kinase kinase; ML
Reward or its denial during the neonatal period affects adult spatial memory and hippocampal phosphorylated cAMP response element-binding protein levels of both the neonatal and adult rat
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; neonatal experience; learning; novelty detection; pCREB; Morris water maze; hippocampusANOVA, analysis of variance; b.w., body weight; CREB, cAMP response element-binding protein; DAB, 3, 3′-diaminobenzidine; DER, denied expected reward; LSD, least square
Hippocampal neuronal death induced by kainic acid and restraint stress is suppressed by exercise
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; chronic exercise; kainic acid; restraint stress; CREB; CaMKII; ERK1/2AD, Alzheimer's disease; CaMKII, calcium/calmodulin-dependent protein kinase II; CREB, cAMP response element-binding protein; ERK1/2, extracellular signal-regulated kinase; Gc, glucocort
Premature ageing of the immune system underlies immunodeficiency in ataxia telangiectasia
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; ATM, ataxia telangiectasia mutated gene product; A-T, ataxia telangiectasia; BCR B, cell receptor; CHK2, cell cycle checkpoint kinase 2; CREB, cAMP response element-binding protein; IGF1, insulin-like growth factor 1; KAP-1, KRAB associated protein; NBS1,
Epigenetic, transcriptional and posttranscriptional regulation of the tyrosine hydroxylase gene
Keywords: CREB، cAMP پروتئین اتصال دهنده المان; AP-1, activator protein 1; ATF1/2, activating transcription factor 1/2; CaMII, calcium/calmodulin dependent protein kinase II; CDP2, CCAAT displacement protein 2; CREB, cAMP response element-binding protein; CREM, cAMP-responsive element modulator; CTFC,