دانلود مقالات ISI درباره Crpc + ترجمه فارسی

Retrospective Review of Percutaneous Image-Guided Ablation of Oligometastatic Prostate Cancer: A Single-Institution Experience

Keywords: ADT; androgen-deprivation therapy; CRPC; castrate-resistant prostate cancer; PET; positron emission tomography; PFS; progression free survival; PSA; prostate-specific antigen; SBRT; stereotactic body radiation therapy;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewC-terminally truncated constitutively active androgen receptor variants and their biologic and clinical significance in castration-resistant prostate cancer

Keywords: aa; amino-acids; ADT; androgen deprivation therapy; AR; androgen receptor; ARΔLBD; androgen receptor lacking a functional ligand binding domain; AR-V; AR splice variant; BET; bromodomain and extra-terminal; CE; cryptic exon; CRPC; castration-resistant pr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Adult UrologyOncology: Prostate/Testis/Penis/UrethraAR-V7 Transcripts in Whole Blood RNA of Patients with Metastatic Castration Resistant Prostate Cancer Correlate with Response to Abiraterone Acetate

Keywords: prostatic neoplasms; castration-resistant; neoplasm metastasis; receptors; androgen; biomarkers; tumor; abiraterone; ALP; alkaline phosphatase; AR; androgen receptor; CRPC; castration resistant prostate cancer; Ct; cycle threshold; CTC; circulating tumor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Neutrophil to Lymphocyte Ratio in Castration-Resistant Prostate Cancer Patients Treated With Daily Oral Corticosteroids

Keywords: CRPC; Dexamethasone; NLR; Prednisolone;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Oleanolic acid methyl ester, a novel cytotoxic mitocan, induces cell cycle arrest and ROS-Mediated cell death in castration-resistant prostate cancer PC-3 cells

Keywords: OA; oleanolic acid; OAME; oleanolic acid methylester; AOA; acetyl oleanolic acid; ΔΨm; mitochondrial membrane potential; CRPC; castration-resistant prostate cancer; FBS; fetal bovine serum; XTT; cell proliferation assay kit; diazald; N-methyl-N-nitroso-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleManumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells

Keywords: Manumycin A; Exosome biogenesis and secretion; Ras signaling; hnRNP H1; Prostate cancer; Alix; ALG-2 interacting protein X; CRPC; castration-resistant prostate cancer; ESCRT; endosomal sorting complex required for transport; EVs; extracellular vesicles; h

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Differential proteome expression analysis of androgen-dependent and -independent pathways in LNCaP prostate cancer cells

Keywords: PC; prostate cancer; CRPC; castration-resistant prostate cancer; AR; androgen receptor; DHT; dihydrotestosterone; FSK; forskolin; Prostate cancer; Castration-resistant prostate cancer; Androgen; Androgen receptor; Proteome;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Maximising the potential of AKT inhibitors as anti-cancer treatments

Keywords: AE; adverse event; CRPC; castrate resistant prostate cancer; DLT; dose limiting toxicity; DNA-PK; DNA-dependent protein kinase; DSB; double strand break; GSK3β; glycogen synthase kinase beta; INPP4B; polyphosphate 4-phosphatase type II; MTD; maximum tole

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of protein kinase C-related kinase (PRK) signalling by the TPα and TPβ isoforms of the human thromboxane A2 receptor: Implications for thromboxane- and androgen- dependent neoplastic and epigenetic responses in prostate cancer

Keywords: ADT; androgen deprivation therapy; AR; androgen receptor; ARE; androgen response element; AA; arachidonic acid; BCR; biochemical recurrence; ChIP; chromatin immunoprecipitation; COX; cyclooxygenase/prostaglandin G2/H2 synathase; CRPC; castrate resistant p

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach

Keywords: Aldo-keto reductase 1C3; AKR1C3; 17β-HSD5; Prostate cancer; CRPC; Bioisosterism; Scaffold hopping; Inhibitors; NWCHXFMRNUJDNB-UHFFFAOYSA-N; HZZCFCAKQYBGLE-UHFFFAOYSA-N; YQJHRNZFIOVGQM-UHFFFAOYSA-N; UHUYUGANTDDPEB-UHFFFAOYSA-N; DWGCYTWMYJCZRX-UHFFFAOYSA-N

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Regulated expression of the TPβ isoform of the human T prostanoid receptor by the tumour suppressors FOXP1 and NKX3.1: Implications for the role of thromboxane in prostate cancer

Keywords: 5-aza-dC; 5-aza-2′-deoxycytidine; AA; arachidonic acid; ADT; androgen deprivation therapy; AR; androgen receptor; BCR; biochemical recurrence; ChIP; chromatin immunoprecipitation; CNA; copy number alteration; COX; cyclooxygenase/prostaglandin G2/H2 synt

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Implementation of the AUA Castration Resistant Prostate Cancer Guidelines into Practice: Establishing a Multidisciplinary Clinic

Keywords: prostatic neoplasms, castration-resistant; standards; continuity of patient care; patient care team; interprofessional relations; CRPC; castrate resistant prostate cancer; MDC; multidisciplinary clinic;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Treatment of metastatic castration-resistant prostate cancer (mCRPC) with enzalutamide

Keywords: ADT; androgen deprivation therapy; AR; androgen receptor; AR-V; androgen receptor splice variant; AR-V7; androgen receptor splice variant 7; ASCO; American Society of Clinical Oncology; CRPC; castration-resistant prostate cancer; CTC; circulating tumor ce

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Androgen-induced miR-27A acted as a tumor suppressor by targeting MAP2K4 and mediated prostate cancer progression

Keywords: microRNA; Androgen receptor; PI3K signaling; ADT; CRPC;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Large-scale evaluation of SLC18A2 in prostate cancer reveals diagnostic and prognostic biomarker potential at three molecular levels

Keywords: Prostate cancer; SLC18A2; Diagnosis; Prognosis; Biomarkers; AN; Adjacent normal; BPH; Benign prostatic hyperplasia; CRPC; Castration-resistant prostate cancer; PIN; Prostate intraepithelial neoplasia; MPC; Metastatic prostate cancer; RP; Radical prostatec

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Human antigen R is positively associated with malignant aggressiveness via upregulation of cell proliferation, migration, and vascular endothelial growth factors and cyclooxygenase-2 in prostate cancer

Keywords: BCR; biochemical recurrence; COX; cyclooxygenase; CRPC; castration-resistant prostate cancer; HO; heme oxygenase; HuR; human antigen-R; IRS; immunoreactive score; KD; knockdown; PCa; prostate cancer; PSA; prostate-specific antigen; RP; radical prostatecto

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Long non-coding RNA: A newly deciphered “code” in prostate cancer

Keywords: Androgen receptor; LNCaP; Biomarker; PCa; prostate cancer; ncRNA; non-coding RNAs; lncRNA; long ncRNA; miRNA; microRNA; snRNA; small nuclear RNA; siRNA; small interfering RNA; tRNA; transfer RNA; rRNA; ribosomal RNA; PCA3; PCa antigen 3; PIN; prostatic in

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

A Whole Blood Assay for AR-V7 and ARv567es in Patients with Prostate Cancer

Keywords: prostatic neoplasms; receptors; androgen; blood; biomarkers; tumor; protein isoforms; AR-FL; full-length androgen receptor; CRPC; castration resistant prostate cancer; CTC; circulating tumor cell; EMT; epithelial-to-mesenchymal transition; EpCAM; epitheli

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Long-Term Administration of Docetaxel Over 70 Cycles for Castration-Resistant Prostate Cancer

Keywords: ARD6563; Chemotherapy; CRPC; Long survival; Metastatic;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

[14C]Fluciclovine (alias anti-[14C]FACBC) uptake and ASCT2 expression in castration-resistant prostate cancer cells

Keywords: Fluciclovine; Anti-FACBC; ASCT2; Prostate cancer; CRPC; Positron emission tomography

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA in prostate cancer

Keywords: DGCR8; Digeorge syndrome chromosomal region 8; CCNDs; cyclin Ds; CDK4; cyclin-dependent kinase 4; CDK6; cyclin-dependent kinase 6; E2F; E2 transcription factor; E2F2; E2 transcription factor 2; IGF1R; insulin-like growth factor 1 receptor; ELK1; ELK1 memb

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Les nouvelles thérapies dans le cancer de la prostate métastatique

Keywords: CRPC; Abiratérone; Enzalutamide; Cabozantinib; MOSCATO; CRPC; Abiraterone; Enzalutamide; Cabozantinib; MOSCATO;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Reconsideration of progression to CRPC during androgen deprivation therapy

Keywords: CRPC; DHEA; Androgen deprivation therapy; Mechanism

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms of drug resistance that target the androgen axis in castration resistant prostate cancer (CRPC)

Keywords: ADMET; absorption distribution, metabolism, elimination and toxicity; Δ4-A; 4-androstene-3,17-dione; Δ5-Adiol; 5-androstene-3β,17β-diol; 3α-Adiol; 5α-androstane-3α,17β-diol; Adione; 5α-androstane-3,17-dione; ADT; androgen deprivation therapy; AR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

A low carbohydrate, high protein diet suppresses intratumoral androgen synthesis and slows castration-resistant prostate tumor growth in mice

Keywords: Prostate cancer; CRPC; Intratumoral androgens; Steroidogenesis; Low carbohydrate high protein diet;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy

Keywords: Prostate cancer; Androgen signaling; Taxanes; Therapeutic resistance; Epithelial-mesenchymal transition; ADT; androgen deprivation therapy; AR; androgen receptor; AR-V; androgen receptor splice variant; CRPC; castration-resistant prostate cancer; DHT; dih

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

A Phase II Study of GW786034 (Pazopanib) With or Without Bicalutamide in Patients With Castration-Resistant Prostate Cancer

Keywords: Angiogenesis inhibitors; CRPC; Patient selection; PSA response;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Next-generation steroidogenesis inhibitors, dutasteride and abiraterone, attenuate but still do not eliminate androgen biosynthesis in 22RV1 cells in vitro

Keywords: DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; LHRH; luteinizing hormone releasing hormone; LH; luteinizing hormone; AR; androgen receptor; CRPC; castration resistant prostate cancer; PSA; prostate specific antigen; SRD5A1/2; 5-alpha-reductase is

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Abiraterone inhibits 1α,25-dihydroxyvitamin D3 metabolism by CYP3A4 in human liver and intestine in vitro

Keywords: 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; P450; cytochrome P450; VDR; vitamin D receptor; LC-MS/MS; liquid chromatography-tandem mass spectrometry; HLM; human liver microsomes; HIM; human intestinal microsomes; CRPC; castration-resistant prostate can

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of PRL1 as a novel diagnostic and therapeutic target for castration-resistant prostate cancer by the Escherichia coli ampicillin secretion trap (CAST) method

Keywords: EGFR; PTP4A1; Prognosis; CRPC; MMP9; Immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Protein kinase A (PKA) pathway is functionally linked to androgen receptor (AR) in the progression of prostate cancer

Keywords: cAMP; cyclic adenosine monophosphate; PKA; protein kinase A; CaP; prostate cancer; CRPC; castration-resistant prostate cancer; PDE; phosphodiesterase; GEO; Gene Expression Omnibus; Rolipram; Forskolin; AR; cAMP/PKA pathways; CaP metastasis;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Development, validation and application of a stable isotope dilution liquid chromatography electrospray ionization/selected reaction monitoring/mass spectrometry (SID-LC/ESI/SRM/MS) method for quantification of keto-androgens in human serum

Keywords: A; androsterone; Adione; 5α-androstane-3,17-dione; Δ4-AD; Δ4-androstene-3,17-dione; ADT; androgen deprivation therapy; CD-FBS; charcoal dextran stripped fetal bovine serum; CRPC; castration resistant prostate cancer; CV; coefficient of variation; DHEA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Targeted disruption of the p160 coactivator interface of androgen receptor (AR) selectively inhibits AR activity in both androgen-dependent and castration-resistant AR-expressing prostate cancer cells

Keywords: ANOVA; analysis of variance; AR; androgen receptor; ARDH; AR DNA and hormone-binding domains; ARNTD; AR amino terminus and DNA-binding domain; ATCC; American Type Culture Collection; CARM-1; coactivator associated arginine methyltransferase-1; CRPC; castr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

New platinum(II) complexes conjugated at position 7α of 17β-acetyl-testosterone as new combi-molecules against prostate cancer: Design, synthesis, structure-activity relationships and biological evaluation

Keywords: Platinum(II) complexes; 17β-Acetyl-testosterone; Combi-molecules; Prostate cancer; Anticancer agents; AR; androgen receptor; CRPC; castration-resistant prostate cancer; CDDP; cisplatin; PSA; prostate-specific antigen; CAM; chick chorioallantoic membrane;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

AR Variant ARv567es Induces Carcinogenesis in a Novel Transgenic Mouse Model of Prostate Cancer

Keywords: AR; androgen receptor; AR-FL; AR full length; AR-Vs; androgen receptor splice variants; ARv567es; AR variant with exons 5, 6, and 7 skipped; CRPC; castration-resistant prostate cancer; EMT; epithelial to mesenchymal transition; GSEA; gene set enrichment a

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenomic Alterations in Localized and Advanced Prostate Cancer

Keywords: ASM; allele-specific methylation; CGI; cytosine guanine dinucleotide (CpG) island; CRPC; castration-resistant prostate cancer; ERRBS; Enhanced Reduced Representation Bisulfite Sequencing; PCa; prostate cancer;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Cross Modulation between the Androgen Receptor Axis and Protocadherin-PC in Mediating Neuroendocrine Transdifferentiation and Therapeutic Resistance of Prostate Cancer

Keywords: ADT; androgen deprivation therapy; AR; androgen receptor; CRPC; castration-resistant prostate cancer; DHT; dihydrotestosterone; NE; neuroendocrine; PCDH-PC; protocadherin-PC;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

ETS1 promotes chemoresistance and invasion of paclitaxel-resistant, hormone-refractory PC3 prostate cancer cells by up-regulating MDR1 and MMP9 expression

Keywords: ETS1; E26 transformation specific sequence 1; MDR1; multi drug resistance 1; uPA; urinary type plasminogen activator; MMP; matrix metalloprotease; ECM; extra cellular matrix; TBP; TATA-binding protein; GAPDH; glyceraldehydes 3 phosphate dehydrogenase; ADT

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Transcript Levels of Androgen Receptor Variant AR-V1 or AR-V7 Do Not Predict Recurrence in Patients with Prostate Cancer at Indeterminate Risk for Progression

Keywords: prostate; prostatic neoplasms; receptors, androgen; neoplasm recurrence, local; prostate-specific antigen; AR; androgen receptor; bDNA; branched chain DNA; CRPC; castration resistant prostate cancer; ERG; Ets related gene; FFPE; formalin fixed, paraffin e

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Design of oxobenzimidazoles and oxindoles as novel androgen receptor antagonists

Keywords: Androgen receptor; AR antagonist; Prostate cancer; Ligand efficiency; CRPC; LBD; NHR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery of 3-aryloxy-lactam analogs as potent androgen receptor full antagonists for treating castration resistant prostate cancer

Keywords: Androgen receptor; AR antagonist; Prostate cancer; Ligand efficiency; Polar surface area; PSA; Castration resistant prostate cancer; CRPC; LBD; NHR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Enhanced expression of organic anion transporting polypeptides (OATPs) in androgen receptor-positive prostate cancer cells: Possible role of OATP1A2 in adaptive cell growth under androgen-depleted conditions

Keywords: AR; androgen receptor; STX64; 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate; CRPC; castration-resistant prostate cancer; STS; steroid sulfatase; OATP; organic anion transporting polypeptide; DHEA; dehydroepiandrosterone; DHEAS; dehydroe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Moving Toward Personalized Medicine in Castration-Resistant Prostate Cancer

Keywords: Castration-resistant prostate cancer; CRPC; Personalized medicine; Androgen receptor; ETS; Next-generation sequencing;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Putting the brakes on continued androgen receptor signaling in castration-resistant prostate cancer

Keywords: AAG; 17-N-allylamino-17-demethoxygeldanamycin; ACTH; adrenocorticotropic hormone; AR; androgen receptor; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element-binding; CRPC; castration-resistant prostate cancer; CYP; cytochrome P450; DHEA; deh

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Recommendations on the management of controversies in advanced castrate-resistant prostate cancer

Keywords: Prostate cancer; CRPC; HRPC; Controversies; Docetaxel; Cabazitaxel; Cáncer de próstata; CPRC; CPHR; Controversias; Docetaxel; Cabazitaxel;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Current second-line treatment options for patients with castration resistant prostate cancer (CRPC) resistant to docetaxel

Keywords: Prostate cancer; CRPC; Second-line therapy; Docetaxel; Targeted therapy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Prostate cancer stem cells: Are they androgen-responsive?

Keywords: ABC; ATP-binding cassette; ADT; androgen deprivation therapy; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukaemia; AR; androgen receptor; BM; basement membrane; CaP; prostate cancer; CARN; castration-resistant nkx3.1-expressing cells; CB; committed

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

CommentaryAntioxidants for prostate cancer chemoprevention: Challenges and opportunities

Keywords: 8-oxo-dG; 8-oxo-2′-deoxyguanosine; ADT; androgen-deprivation therapy; AR; androgen receptor; ARE; antioxidant response element; ATBC; Alpha-Tocopherol, Beta-Carotene; BPH; benign prostatic hyperplasia; CARET; Carotene and Retinol Efficacy Trial; CRPC; c

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

ASC-J9 Suppresses Castration-Resistant Prostate Cancer Growth through Degradation of Full-length and Splice Variant Androgen Receptors

Keywords: AR; androgen receptor; CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; fAR; full-length AR; shAR3; short-hairpin AR3;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Design, synthesis, and biological evaluation of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists

Keywords: AR; androgen receptor; CRPC; castration-resistant prostate cancer; CAB; combined androgen blockade; DHT; dihydrotestosterone; SAR; structure-activity relationship; EDC; N-[3-(dimethylamino)propyl]-N′-ethylcarbodiimide hydrochloride; DMT-MM; 4-(4,6-dim

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه