Keywords: کروزاین; Chagas disease; Human african trypanosomiasis; Cruzain; Rhodesain; Inhibitors; Synthesis;
مقالات ISI کروزاین (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: کروزاین; Molecular simplification; 4-Aminoquinolines; 4-Aminopyrimides; Cruzain; Rhodesain; Chagas disease;
Keywords: کروزاین; BBB; blood-brain barrier; CNS; central nervous system; HAT; human African trypanosomiasis; NTDs; neglected tropical diseases; PDB; Protein Data Bank; PPPs; public-private partnerships; R&D; research and development; RNAi; RNA interference; SBDD; structure
Keywords: کروزاین; Chagas' disease; Cruzain; Protease inhibitors; Pharmacokinetics; Lead optimization;
New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8
Keywords: کروزاین; Cysteine protease; Inhibitor; Aziridine; Rhodesain; Cruzain; Leishmania; DCC; Dicyclohexylcarbodiimide; DMAP; 4-(Dimethylamino)pyridine; DPSI; (S,S)-Diphenylsulfimine; GB/VI methodology; Generalized Born/Volume Integral methodology; LE; ligand efficiency;
Gold(III) complexes with ONS-Tridentate thiosemicarbazones: Toward selective trypanocidal drugs
Keywords: کروزاین; Gold(III) complexes; Thiosemicarbazones; Cruzain; Trypanosoma cruzi; Chagas disease;
New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi
Keywords: کروزاین; Antiprotozoal agents; Chagas disease; Thiazole; Hydrazones; Cruzain; Electron microscopy;
Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain
Keywords: کروزاین; Chagas disease; Trypanosoma cruzi; Conformationally constrained analogs; Thiosemicarbazone; Cruzain; Necrosis;
Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of α-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum
Keywords: کروزاین; Malaria; Peptidomimetic; Falcipain; Cruzain; Drug resistance
Design, synthesis and biological evaluation of new aryl thiosemicarbazone as antichagasic candidates
Keywords: کروزاین; Chagas disease; Thiosemicarbazone; Oxidative stress; Cruzain; Docking; MutagenicityMOLCDPMVIXILLZ-MXZHIVQLSA-N; FJCDJOPKILSQQC-WUXMJOGZSA-N; IKXKPKRBUBTOBD-WUXMJOGZSA-N; ULDWASCYNZEGGY-MXZHIVQLSA-N; VAOJXJAGBHUCPY-LFYBBSHMSA-N; OIHUOBSUZMQSOX-LFYBBSHMSA-N
Antitrypanosomal and cysteine protease inhibitory activities of alkyldiamine cryptolepine derivatives
Keywords: کروزاین; Cryptolepine; Indoloquinolines; Trypanosoma; Cruzain; Rhodesain;
Computational study on the inhibition mechanism of cruzain by nitrile-containing molecules
Keywords: کروزاین; Cruzain; Cysteine proteases; Density functional theory; Semi-empirical quantum mechanics; Trypanosoma cruzi
Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice
Keywords: کروزاین; Chagas disease; Trypanosoma cruzi; Cruzain; Oxadiazoles; Hydrazones; Bioisosterism;
Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases
Keywords: کروزاین; Protease inhibitors; Cruzain; Rhodesain; Vinylsulfone
Quantitative structure–activity relationships for a series of inhibitors of cruzain from Trypanosoma cruzi: Molecular modeling, CoMFA and CoMSIA studies
Keywords: کروزاین; Cruzain; Drug design; Chagas’ disease; CoMFA; CoMSIA
Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents
Keywords: کروزاین; Trypanosoma cruzi; Oxadiazole; N-Acylhydrazone; Privileged structures; Molecular docking; Cruzain
Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates
Keywords: کروزاین; Quinoxaline-N-acylhydrazone (NAH) derivatives; Trypanosoma cruzi; Chagas disease; Docking; Cruzain
2D QSAR and similarity studies on cruzain inhibitors aimed at improving selectivity over cathepsin L
Keywords: کروزاین; HQSAR; ROCS; Cruzain; Cathepsin L; Chagas’ disease
Development of α-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease
Keywords: کروزاین; Chagas disease; Cruzain; Cysteine protease inhibitors; Structure-based library design