Keywords: CSCs، سلول های بنیادی سرطانی; Small cell lung cancer; Cellular immunotherapy; Maintenance therapyCBR, clinical benefit rate; CI, confidence interval; CIK, cytokine-induced killer; CIT, cellular immunotherapy; CR, complete remission; CT, computed tomography; CSCs, cancer stem cells; CT
مقالات ISI CSCs، سلول های بنیادی سرطانی (ترجمه نشده)
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Keywords: CSCs، سلول های بنیادی سرطانی; ES cell, embryonic stem cell; CSCs, cancer stem cells; IR, ionizing radiation; RT-PCR, reverse transcription polymerase chain reaction; Cy3, cyanine 3; Cy5, cyanine 5; GO, gene ontology; Gy, gray; qRT-PCR, quantitative real-time RT-PCR; SD, standard devia
Keywords: CSCs، سلول های بنیادی سرطانی; Clinical trials; Biomarkers; Diarrhea; Notch signaling; Monoclonal antibodies (mAbs); γ-Secretase inhibitorsADAM, a disintegrin and metalloproteases; CR, complete response; CSCs, cancer stem cells; DLL, Delta-like ligand; DLT, dose limiting toxicity; EDTA
Keywords: CSCs، سلول های بنیادی سرطانی; NK, nature killer cells; CSCs, cancer stem cells; ROS, redox oxygen species; ULBP, UL16-binding proteins; MIC, MHC class I chain–related moleculesCancer stem cells; NK cells; NKG2D; ROS
CD24 suppresses malignant phenotype by downregulation of SHH transcription through STAT1 inhibition in breast cancer cells
Keywords: CSCs، سلول های بنیادی سرطانی; Breast cancer; CD24; Sonic hedgehog; STAT1; Cancer stem cellHh, hedgehog; BCCs, breast cancer cells; CSCs, cancer stem cells
The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair
Keywords: CSCs، سلول های بنیادی سرطانی; Breast cancer stem cells; Chloroquine; Mitochondrial damage; Oxidative stressTNBC, triple negative breast cancer; CSCs, cancer stem cells; CQ, chloroquine; FACS, fluorescence-activated cell sorting; MSFE, mammosphere formation efficiency; EM, electron mic
Lipopolysaccharide supports maintaining the stemness of CD133+ hepatoma cells through activation of the NF-κB/HIF-1α pathway
Keywords: CSCs، سلول های بنیادی سرطانی; HCC, hepatocellular carcinoma; CSCs, cancer stem cells; TICs, tumor initiating cells; LPS, lipopolysaccharide; EMT, epithelial–mesenchymal transition; FBS, fetal bovine serum; 5-Fu, 5-fluorouracil; TLR4, toll-like receptor 4; PAMPs, pathogen-associated mo
Aldehyde dehyderogenase (ALDH1A1) delineating the normal and cancer stem cells in spectral lung lesions: An immunohistochemical appraisal
Keywords: CSCs، سلول های بنیادی سرطانی; ALDH1A1; Lung; NSCLCs; SCLCALDH1A1, aldehyde dehyderogenase 1A1; NSCLC, non small cell lung cancer; SCLC, small cell lung cancer; CSCs, cancer stem cells; IASLC/ATS/ERS, International Association for the Study of the Lung Cancer/American Thoracic Society/
Phosphodiesterase 5/protein kinase G signal governs stemness of prostate cancer stem cells through Hippo pathway
Keywords: CSCs، سلول های بنیادی سرطانی; Cancer stem cells; Stemness; PDE5; Hippo pathway; TAZ5'-GMP, guanosine-5'-monophosphate; cGMP, cyclic guanosine monophosphate; CSCs, cancer stem cells; ED, erectile dysfunction; eNOS, endothelial NOS; GC, guanylyl cyclase; iNOS, inducible NOS; LATS, nucle
CD44highCD24low molecular signature determines the Cancer Stem Cell and EMT phenotype in Oral Squamous Cell Carcinoma
Keywords: CSCs، سلول های بنیادی سرطانی; CD, Cluster of differentiation; CSCs, Cancer Stem Cells; EMT, Epithelial to mesenchymal transition; OSCC, Oral Squamous Cell Carcinoma; SP, Side Population; ABC, ATP-binding Cassette
Autophagy contributes to the enrichment and survival of colorectal cancer stem cells under oxaliplatin treatment
Keywords: CSCs، سلول های بنیادی سرطانی; Colorectal cancer; Autophagy; Cancer stem cells; ChemoresistanceCRC, colorectal cancer; CSCs, cancer stem cells; 5-FU, 5-fluorouracil; OXA, oxaliplatin; H/S, hypoxia/starvation environment; 3-MA, 3-methyladenine; CQ, chloroquine
Human papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation
Keywords: CSCs، سلول های بنیادی سرطانی; HPV, Human papillomavirus; CSCs, Cancer stem cells; OSCC, Oral/oropharyngeal squamous cell carcinomas; miRNA, MicroRNA; IL4, ALDH1, Aldehyde dehydrogenase 1; siRNA, small interfering RNAHPV; OSCC; cancer stem cells; miR-181
TGF-β1 acts through miR-155 to down-regulate TP53INP1 in promoting epithelial–mesenchymal transition and cancer stem cell phenotypes
Keywords: CSCs، سلول های بنیادی سرطانی; Epithelial–mesenchymal transition; Cancer stem cell; MiR-155; Tumour sphere; TP53INP1EMT, epithelial–mesenchymal transition; CSCs, cancer stem cells; TGF-β1, transforming growth factor β1
miRNAs in pancreatic cancer: Therapeutic potential, delivery challenges and strategies
Keywords: CSCs، سلول های بنیادی سرطانی; Ago, Argonaute; ASO, Antisense oligonucleotide; bFGF, Basic fibroblast growth factor; CPP, Cell-penetrating peptide; CSCs, Cancer stem cells; cRGD, Cyclo Arg-Gly-Asp; DNA, Deoxyribonucleic acid; ECM, Extracellular matrix; EGFR, Epidermal growth factor rec
The pharmacological impact of ATP-binding cassette drug transporters on vemurafenib-based therapy
Keywords: CSCs، سلول های بنیادی سرطانی; ABC transporter; Drug resistance; Melanoma; P-glycoprotein; VemurafenibABC, ATP-binding cassette; AML, acute myeloid leukemia; BBB, blood–brain barrier; CNS, central nervous system; CSCs, cancer stem cells; GI, gastrointestinal; MAPK, mitogen-activated pr
MiR-34a regulates therapy resistance by targeting HDAC1 and HDAC7 in breast cancer
Keywords: CSCs، سلول های بنیادی سرطانی; CSCs, cancer stem cells; HDAC, histone deacetylase; HSP70, heat shock protein 70; 3′UTR, 3′ untranslated region; HDACi, histone deacetylase inhibitormicroRNA; Histone deacetylase; Deacetylation; HSP70
Maintenance of the stemness in CD44+ HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression
Keywords: CSCs، سلول های بنیادی سرطانی; CRC, colorectal carcinoma; CSCs, cancer stem cells; HA, hyaluronan; EMT, epithelial–mesenchymal transition; miRNAs, microRNAs; FCS, fetal calf serum; FACS, fluorescence activated cell sorting; ChIP, chromatin immunoprecipitation; shRNA, short hairpin RNA;
Embryonic signature in breast cancers; Pluripotency roots of cancer stem cells
Keywords: CSCs، سلول های بنیادی سرطانی; CSCs, cancer stem cells; ALDH, aldehyde dehydrogenase; SP, side population cells; GSK, glycogen synthase kinaseCancer stem cells (CSCs); Breast tumorigenesis; Pluripotency gene
Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells
Keywords: CSCs، سلول های بنیادی سرطانی; Notch signaling; EMT; EndMT; Cancer stem cells; Notch inhibitorsADAM10/17, A Disintegrin And Metalloprotease 10/17; CSCs, cancer stem cells; CSL, CBF-1, Suppressor of Hairless/LAG1; EGFR, epidermal growth factor receptor; EMT, epithelial mesenchymal trans
Liver tumor-initiating cells as a therapeutic target for hepatocellular carcinoma
Keywords: CSCs، سلول های بنیادی سرطانی; Chemoresistance; HCC; Self-renewal; Tumor-initiating cells; TumorigenicityALDH, aldehyde dehydrogenase; CSCs, cancer stem cells; EpCAM, epithelial cell adhesion molecule; GEP, granulin–epithelin precursor; OSM, oncostatin; PTEN, phosphatase and tensin hom
Exploring stemness gene expression and vasculogenic mimicry capacity in well- and poorly-differentiated hepatocellular carcinoma cell lines
Keywords: CSCs، سلول های بنیادی سرطانی; VM, vasculogenic mimicry; HCC, hepatocellular carcinoma; EMT, epithelial–mesenchymal transition; CSCs, cancer stem cells; HGF, hepatocyte growth factor; VEGF, vascular endothelial growth factor; MMPs, matrix metalloproteinases; qRT-PCR, quantitative rever
Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells
Keywords: CSCs، سلول های بنیادی سرطانی; CSCs, cancer stem cells; PARR, (ADP-ribose) polymerase (PARP); PKC-δ, protein kinase C delta; ROTT, rottlerinAutophagy; Pancreatic cancer; Apoptosis; PI3K; AKT; Rottlerin; Atg7; Beclin1
Suicide gene therapy in cancer: Where do we stand now?
Keywords: CSCs، سلول های بنیادی سرطانی; AMSCs, adipose tissue mesenchymal stromal cells; CD, cytosine deaminase; CSCs, cancer stem cells; DOTAP, 1,2-dioleoyl-3-(trimethylammonium) propane; Chol, cholesterol; 5-FC, 5-fluorocytosine; 5-FU, 5-fluorouracil; GCV, ganciclovir; GvHD, graft-versus-host
Emerging inorganic nanomaterials for pancreatic cancer diagnosis and treatment
Keywords: CSCs، سلول های بنیادی سرطانی; MDR, multidrug resistance; P-gp, P-glycoprotein; CSCs, cancer stem cells; SPIONs, super-paramagnetic iron oxide nanoparticles; CNTs, carbon nanotubes; SWNTs, single-walled carbon nanotubes; MWNTs, multi-walled carbon nanotubes; siRNA, small interfering RN
Glioma stem cells targeted by oncolytic virus carrying endostatin–angiostatin fusion gene and the expression of its exogenous gene in vitro
Keywords: CSCs، سلول های بنیادی سرطانی; GSCs, glioma stem cells; CSCs, cancer stem cells; HSV-1, herpes simplex virus type 1; Endo–Angio, endostatin and angiostatin; GBM-SCs, glioblastoma stem cells; WHO, the world health organization; HBMEC, human brain microvascular endothelial cells; MOI, mu
Cancer stem cells sustaining the growth of mouse melanoma are not rare
Keywords: CSCs، سلول های بنیادی سرطانی; CSC, cancer stem cell; CSCs, cancer stem cells; FBS, fetal bovine serum; SFM, serum-free medium; SP, side population; DMEM, Dulbecco’s modified Eagle’s mediumCancer stem cell; Side population; B16-F10; Tumor sphere
Immunohistochemical staining of cancer stem cell markers in hepatocellular carcinoma
Keywords: CSCs، سلول های بنیادی سرطانی; ALDH, Aldehyde dehydrogenase; CSCs, Cancer stem cells; DAPI, 4′,6-Diamidino-2-phenylindole; HB, Hepatoblastoma; HCC, Hepatocellular carcinomaAldehyde dehydrogenase; Cancer stem cells; CD44; CD90; CD133; Hepatocellular carcinoma and hepatoblastoma
Spheres derived from the human SK-RC-42 renal cell carcinoma cell line are enriched in cancer stem cells
Keywords: CSCs، سلول های بنیادی سرطانی; Tumor spheres; Cancer stem cells; Renal cell carcinoma; Immunological phenotype; Immune evasionRCC, renal cell carcinoma; CSCs, cancer stem cells; SFCs, sphere-forming cells; MACs, monolayer adherent cells; FBS, fetal bovine serum; SFM, serum-free medium;
Chemokines in neuroectodermal development and their potential implication in cancer stem cell-driven metastasis
Keywords: CSCs، سلول های بنیادی سرطانی; NC, neural crest; CSCs, cancer stem cells; EMT, epithelial–mesenchymal transition; CNS, central nervous systemNeuroectoderm; CNS; Neural crest; EMT; Chemokines; Cancer stem cells; Metastasis
Targeting cancer stem cells for more effective therapies: Taking out cancer's locomotive engine
Keywords: CSCs، سلول های بنیادی سرطانی; CSCs, cancer stem cells; CML, chronic myeloid leukemia; SCLC, small cell lung carcinoma; NSCLC, non-small cell lung carcinoma; HCC, hepatocellular carcinoma; 5-FU, 5-fluorouracil; SP, side population; DCIS, ductal carcinoma in situ; PI3K, phosphatidylinos
Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter
Keywords: CSCs، سلول های بنیادی سرطانی; CRC, colorectal carcinoma; CSCs, cancer stem cells; ECM, extracellular matrix; HCC, hepatocellular carcinoma; 3D, three-dimensionalCancer stem cells; Tumour-initiating cells; Hepatocellular carcinoma; Colorectal carcinoma; Migration
Abnormal differentiation, hyperplasia and embryonic/perinatal lethality in BK5-T/t transgenic mice
Keywords: CSCs، سلول های بنیادی سرطانی; Cytokeratin 5; Stem cells; Differentiation; SV40 large T; Tongue papillae; TransgenicBK5, bovine keratin 5; CK5, cytokeratin 5; CSCs, cancer stem cells; SCs, stem cells; SV40 T/t, Simian Virus 40 large T and small t antigens
Evolution of cancer stem cells
Keywords: CSCs، سلول های بنیادی سرطانی; CSCs, cancer stem cells; TA, transiently amplifying precursors; LOH, loss of heterozygosity; LOI, loss of imprinting; EZH2, enhancer of Zeste homolog 2; hTERT, human telomerase reverse transcriptase; mtDNA, mitochondrial genome; ROS, reactive oxygen speci
Identification and Characterization of Tumorigenic Liver Cancer Stem/Progenitor Cells
Keywords: CSCs، سلول های بنیادی سرطانی; AFP, α-fetoprotein; ALB, albumin; CSCs, cancer stem cells; CK18, cytokeratin 18; HCC, hepatocellular carcinoma; IHC, immunohistochemistry; TTR, transthyretin