Keywords: ARE; antioxidant response elements; CBP; CREB binding protein; CK2; casein kinase 2; Cul3; Cullin 3; IBD; inflammatory bowel disease; IFN-γ; interferon-γ; IKK; IkB kinase; IL-1 β; interleukine-1 β; iNOS; inducible nitric oxide synthase; JAKs; Janus Ki
مقالات ISI (ترجمه نشده)
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Keywords: ARE; Antioxidant responsive element; Cul3; Cullin 3; DEVD; Asp-Glu-Val-Asp; DOX; Doxorubicin; GCLC; Catalytic subunit of glutamate-cysteine ligase; GCLM; Modified subunit of glutamate-cysteine ligase; GSTA4-4; Glutathione S-transferase alpha 4;
Keywords: Bcl-2; B cell lymphoma 2; Bcl-xL; B cell lymphoma-extra large; ARE; antioxidant-response element; Cul3; cullin 3; Cyt c; cytochrome c; Drp1; dynamin-related protein 1; ERK; extracellular signal-regulated kinase; GSH; glutathione; GST; glutathione S-tran
A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis
Keywords: ASK1; apoptosis signal regulating kinase 1; Cul3; cullin 3; DEF; dimethylfumarate; DEM; diethylmaleate; 15d-PGJ2; 15-deoxy-Î12,14-prostaglandin J2; FBS; fetal bovine serum; 5-HI; 5-hydroxyoxindole derivative; HO-1; heme oxygenase-1; iNOS; inducible NO sy
RNA-Seq analysis of peripheral blood mononuclear cells reveals unique transcriptional signatures associated with disease progression in dengue patients
Keywords: PBMCs; peripheral blood mononuclear cells; ELISA; enzyme-linked immunosorbent assay; GAPDH; Glyceraldehyde 3-phosphate dehydrogenase; MPO; Myeloperoxidase; EPHB2; Ephrin type-B receptor 2; ISG15; interferon-stimulated gene 15; USP18; ubiquitin specific pe
Molecular evolution of antioxidant and hypoxia response in long-lived, cancer-resistant blind mole rats: The Nrf2-Keap1 pathway
Keywords: Nrf2; nuclear factor erythroid 2-related factor 2; ROS; reactive oxygen species; ARE; antioxidant response element; EpRE; electrophile response element; Keap1; Kelch-like ECH-associated protein 1; EPO; erythropoietin; VEGF; vascular endothelial growth fac
Proteins involved in sleep homeostasis: Biophysical characterization of INC and its partners
Keywords: Protein-protein interactions; Protein stability; Binding; Homologs; Solution scattering; KCTD; Potassium Channel Tetramerization Domain proteins; BTB; Bric-Ã -brack, Tram-track, Broad complex; Cul3; cullin 3; Cul3NTD; N-terminal region of Cul3 (residues 2
The complex role of NRF2 in cancer: A genomic view
Keywords: NRF2; KEAP1; CUL3; Somatic mutations; Cancer;
Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP
Keywords: Nrf2; Keap1; GSK-3; PKB/Akt; PI3K; PTEN; β-TrCP; ARE; antioxidant response element; tBHQ; tert-butyl hydroquinone; bZIP; basic-region leucine zipper; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; CNC; cap'n'collar; Cul1; cullin-1; Cu
Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms
Keywords: Akt PKB; protein kinase B; APAP; acetaminophen; ALT; alanine aminotransferase; ARE; antioxidant response element; β-Trcp; beta-transducin repeat containing protein; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; Cul3; cullin-3; DMSO;
An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy
Keywords: AA; Ascorbic acid; AEM1; ARE expression modulator 1; AEG1; Astrocyte elevated gene-1; Akt; Protein kinase B; AMPK; AMP-activated protein kinase; APL; Acute promyelocytic leukemia; ARE; Antioxidant response element; ATO; Arsenic trioxide; Bach; BTB and CNC
The transcriptional programs of iNKT cells
Keywords: α-GalCer; α-galactosylceramide; BTB-POZ-ZF; broad complex, tramtrack, bric-a-brac or poxvirus and zinc finger; CCR2; C-C chemokine receptor type 2; CCR10; C-C chemokine receptor type 10; ChIP-seq; chromatin immunoprecipitation with deep sequencing
Identification of Arabidopsis MYB56 as a Novel Substrate for CRL3BPM E3 Ligases
Keywords: CUL3; BPM; MYB; transcription factor; E3 ligase; flowering
Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators
Keywords: Nrf2; Keap1; Protein-protein interaction; Transcription factor; Cul3; Keap1/Nrf2 interaction; BTB; Broad complex, Tramtrack and Bric-Ã -Brac; LE; Ligand efficiency; DMEM; Dubecco's modified Eagle's medium; FBS; fetal bovine serum; HMOX1; heme oxygenase
Functional polymorphisms in Nrf2: implications for human disease
Keywords: AAO; age at onset; ALI; acute lung injury; AMD; age-related macular degeneration; ARE; antioxidant response element; BPD; bronchopulmonary dysplasia; β-TrCP; β-transducin repeats-containing proteins; CCA; cholangiocarcinoma; Cns; non-synonymous coding;
Research ArticleThe genomic landscape of hepatoblastoma and their progenies with HCC-like features
Keywords: HB; hepatoblastoma; HCC; hepatocellular carcinoma; CTNNB1; beta catenin; NFE2L2; nuclear factor (erythroid-derived 2)-like 2; TERT; telomerase reverse-transcriptase; NQO1; NAD(P)H: quinone oxidoreductase 1; KEAP1; kelch-like ECH-associated protein 1; CUL3
Targeting Nrf2-Keap1 signaling for chemoprevention of skin carcinogenesis with bioactive phytochemicals
Keywords: 4-HNE; 4-hydroxynonenal; 8OH-dG; 8-hydroxy-2â²deoxyguanosine; AMPK; cyclic-AMP-activated protein kinase; ARE; antioxidant response element; ATF; activating transcription factor; B[a]P; Benzo[a]pyrene; Bach1; broad-complex, tramtrack and bric a brac; CBP;
Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling
Keywords: ARE; antioxidant response element; Cul3; Cullin 3; DAPI; 4â²,6-diamidino-2-phenylindole; EMSA; electrophoretic mobility shift assay; EpRE; electrophile-responsive element; ERK; extracellular signal-regulated protein kinase; GSH; glutathione; GSK-3β; gly
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography
Keywords: 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi
Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3–SPOP E3 ubiquitin ligase complex
Keywords: BRMS1; SPOP; Cul3; Ubiquitination; Breast cancer cells
Genetic Disruption of KEAP1/CUL3 E3 Ubiquitin Ligase Complex Components is a Key Mechanism of NF-KappaB Pathway Activation in Lung Cancer
Keywords: KEAP1; CUL3; RBX1; IKBKB; NF-κB signaling; Genetic disruption
Adaptive response to oxidative stress: Bacteria, fungi, plants and animals
Keywords: AHP1; alkylhydroperoxide reductase; AHR; aryl hydrocarbon receptor; ARE; antioxidant response element; 2CPA; 2-Cys peroxiredoxin-A; CRD; cysteine rich domain; Cul3; Cullin 3; DPH; diphenylhexatriene; EpRE; electrophile response element; ERK; extracellular
Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1–Cul3 interaction
Keywords: Keap1; Nrf2; Arsenic; Cul3; E3 ubiquitin ligase
Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species
Keywords: ARE; Antioxidant-responsive element; BHA; Butylated hydroxyanisole; BTB; Broad complex-tramtrack-bric-a-brac; bZip; Basic leucine zipper; CBP; CREB binding protein; C/EBPβ; CCAAT/enhancer binding protein β; CNC; Cap' n' collar; Cox2; Cyclooxygenase