Keywords: Nitric oxide synthase (NOS); Inducible NOS (iNOS); Endothelial NOS (eNOS); Cyclooxygenase-2 (COX-2); COX-2; Oxidative stress; Cardiovascular diseases;
مقالات ISI (ترجمه نشده)
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Fusopoltide A and fusosterede A, A polyketide with a pentaleno[1,2-c]pyran ring system and A degraded steride, from the fungus Fusarium solani
Keywords: Fusarium solani; Polyketide; Degraded steride; X-ray; Cyclooxygenase-2 (COX-2);
PM2.5 exposure stimulates COX-2-mediated excitatory synaptic transmission via ROS-NF-κB pathway
Keywords: Fine particulate matter (PM2.5); Neurological damage; Reactive oxygen species (ROS); Nuclear factor kappa B (NF-κB); Cyclooxygenase-2 (COX-2); PM2.5; Fine particulate matter; COX-2; Cyclooxygenase-2; ROS; Reactive oxygen species; fEPSP; Field excitatory
MicroRNA-143-3p inhibits growth and invasiveness of melanoma cells by targeting cyclooxygenase-2 and inversely correlates with malignant melanoma progression
Keywords: Malignant melanoma; miR-143-3p; Cyclooxygenase-2 (COX-2); Inflammation; Tumorigenesis;
Teriparatide (human PTH1-34) compensates for impaired fracture healing in COX-2 deficient mice
Keywords: Cyclooxygenase-2 (COX-2); Fracture healing; Parathyroid hormone (PTH); Periosteum; Prostaglandin;
Impact of structural alterations on the radiopharmacological profile of 18F-labeled pyrimidines as cyclooxygenase-2 (COX-2) imaging agents
Keywords: Positron emission tomography (PET); Cyclooxygenase-2 (COX-2); Radiopharmacology; Fluorine-18;
Cyclooxygenase-2 identified as a potential target for novel radiomodulator scopolamine methyl bromide: An in silico study
Keywords: Scopolamine methyl bromide; Antagonist; Cyclooxygenase-2 (Cox-2);
Cyanidin-3-O-glucoside inhibits the UVB-induced ROS/COX-2 pathway in HaCaT cells
Keywords: Cyanidin-3-O-glucoside; HaCaT cells; Ultraviolet B (UVB); Reactive oxygen species (ROS); Cyclooxygenase-2 (COX-2);
Activated hepatic stellate cells directly induce pathogenic Th17 cells in chronic hepatitis B virus infection
Keywords: Chronic hepatitis B; Hepatic stellate cells (HSCs); Th17 cells; Cyclooxygenase-2 (COX-2); Prostaglandin E2 (PGE2);
Celecoxib treatment of fibrous dysplasia (FD) in a human FD cell line and FD-like lesions in mice with protein kinase A (PKA) defects
Keywords: Cyclic AMP; Prostaglandin E2; Cyclooxygenase-2 (COX-2); Bone tumors; McCune-Albright syndrome; Carney complex;
Homeopathic Rhus toxicodendron has dual effects on the inflammatory response in the mouse preosteoblastic cell line MC3T3-e1
Keywords: Rhus toxicodendron (Rhus tox); Cyclooxygenase-2 (COX-2); Prostaglandin E2 (PGE2); Nitric oxide (NO) generation;
Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease
Keywords: Anandamide (AEA); β-amyloid; Cerebral glucose uptake; Cannabinoid CB2 receptor; Cyclooxygenase-2 (COX-2); Positron emission tomography (PET); 2-AG; 2-arachidonoylglycerol; 3Rs; replacement, refinement and reduction of animals in research; ABDH6/12; α/β
Preventive effect of Rhus javanica extract on UVB-induced skin inflammation and photoaging
Keywords: Rhus javanica extract (RJE); Inflammation; Photoaging; Cyclooxygenase-2 (COX-2); Matrix metalloproteinase-1 (MMP-1), mitogen-activated protein kinases (MAPKs), epidermal growth factor receptor (EGFR); RJE; Rhus javanica extract (Gall); COX-2; cyclooxygena
Exercise suppresses COX-2 pro-inflammatory pathway in vestibular migraine
Keywords: Cyclooxygenase-2 (COX-2); Vestibular; Migraine; Exercise
Co-administration of subtherapeutic diazepam enhances neuroprotective effect of COX-2 inhibitor, NS-398, after lithium pilocarpine-induced status epilepticus
Keywords: COX-2; cyclooxygenase-2; EEG; electroencephalogram; PGE2; prostaglandin E2; SE; status epilepticus; cyclooxygenase-2 (COX-2); inflammation; neuroprotection;
Celecoxib sensitizes imatinib-resistant K562 cells to imatinib by inhibiting MRP1-5, ABCA2 and ABCG2 transporters via Wnt and Ras signaling pathways
Keywords: Imatinib mesylate; Chronic myeloid leukemia (CML); ABC transporters; Cyclooxygenase-2 (COX-2); Celecoxib;
Research PaperEffects of taraxasterol on iNOS and COX-2 expression in LPS-induced RAW 264.7 macrophages
Keywords: Taraxasterol; Inducible nitric oxide synthase (iNOS); Cyclooxygenase-2 (COX-2); Mitogen-activated protein kinase (MAPK);
Different detectability of cyclooxygenase-2 (COX-2) protein in standard paraffin sections and tissue microarrays of human melanomas and naevi – Comparative study
Keywords: Cyclooxygenase-2 (COX-2); Immunohistochemistry; Marker; Melanoma; Tissue microarrays (TMAs)
Valproic acid suppresses lipopolysaccharide-induced cyclooxygenase-2 expression via MKP-1 in murine brain microvascular endothelial cells
Keywords: AREs; AU-rich elements; BBB; blood-brain barrier; C/EBPβ; CCAAT enhancer binding protein beta; CNS; central nervous system; COX-2; cyclooxygenase-2; HAT; histone acetyltransferase; HDAC; histone deacetylase; JNK; c-Jun N-terminal kinase; LPS; lipopolys
Coordinate regulation between the nuclear receptor peroxisome proliferator-activated receptor-γ and cyclooxygenase-2 in renal epithelial cells
Keywords: Hyperosmolarity; Cyclooxygenase-2 (COX-2); Peroxisome proliferator-activated receptor gamma (PPARγ); Nephroprotection; Thiazolidinediones (TZD);
Sodium arsenite induces cyclooxygenase-2 expression in human uroepithelial cells through MAPK pathway activation and reactive oxygen species induction
Keywords: Human uroepithelial cell; Arsenite; Cyclooxygenase-2 (COX-2); Mitogen-activated protein kinase (MAPK); Reactive oxygen species (ROS);
Suppression of LPS-induced inflammatory activities by Rosmarinus officinalis L.
Keywords: Rosmarinus officinalis L.; Rosemary; Anti-inflammation; Inducible nitric oxide synthase (iNOS); Cyclooxygenase-2 (COX-2); Macrophage RAW 264.7 cells; 4â²-Methoxytectochrysin;
Amentoflavone inhibits iNOS, COX-2 expression and modulates cytokine profile, NF-κB signal transduction pathways in rats with ulcerative colitis
Keywords: Amentoflavone; Acetic acid; Ulcerative colitis; Pro-inflammatory cytokines; Inducible nitric oxide synthase (iNOS); Cyclooxygenase-2 (COX-2);
Keywords: Rhus toxicodendron (Rhus tox); Cyclooxygenase-2 (COX-2); Type II collagenase (col-II); Prostaglandin E2 (PGE2); MTT assay; RT-PCR; Immunoblot analysis
An apple oligogalactan suppresses endotoxin-induced cyclooxygenase-2 expression by inhibition of LPS pathways
Keywords: An apple oligogalactan (AOG); Lipopolysaccharide (LPS); Cyclooxygenase-2 (COX-2)
Ginsenoside-Rd exhibits anti-inflammatory activities through elevation of antioxidant enzyme activities and inhibition of JNK and ERK activation in vivo
Keywords: Ginsenoside-Rd; Inducible nitric oxide synthase (iNOS); Cyclooxygenase-2 (COX-2); Antioxidant enzymes; Nuclear factor-κB (NF-κB); Mitogen-activated protein kinases (MAPKs)
Assessment of radioligands for PET imaging of cyclooxygenase-2 in an ischemic neuronal injury model
Keywords: Autoradiography; Brain ischemia; Inflammation; Molecular imaging; Positron emission tomography (PET); Cyclooxygenase-2 (COX-2)
Antioxidant, anti-proliferative and cyclooxygenase-2 inhibitory activities of ethanolic extracts from lemon balm (Melissa officinalis L.) leaves
Keywords: Antioxidant; Anti-proliferative; Cyclooxygenase-2 (COX-2); Drying; Melissa officinalis L.;
Antimetastatic activity of pinosylvin, a natural stilbenoid, is associated with the suppression of matrix metalloproteinases
Keywords: Pinosylvin; Antimetastasis; Matrix metalloproteinase (MMP); Cyclooxygenase-2 (COX-2); Pulmonary metastasis model
Design and synthesis of 4-O-methylhonokiol analogs as inhibitors of cyclooxygenase-2 (COX-2) and PGF1 production
Keywords: VCVXWPYYXAANOC-UHFFFAOYSA-N; ZLILBVDASFKRRG-UHFFFAOYSA-N; MYNNLJQBOAOOAA-UHFFFAOYSA-N; QBILFJJRRZNZKH-UHFFFAOYSA-N; AXGJZAMTTKNCTL-UHFFFAOYSA-N; 4-O-Methylhonokiol; Cyclooxygenase-2 (COX-2); Aryl carbamate; Isoxazole; Triazole;
Dipyridamole inhibits lipopolysaccharide-induced cyclooxygenase-2 and monocyte chemoattractant protein-1 via heme oxygenase-1-mediated reactive oxygen species reduction in rat mesangial cells
Keywords: Dipyridamole; Lipopolysaccharide; Cyclooxygenase-2 (COX-2); Monocyte chemoattractant protein-1 (MCP-1); Heme oxygenase-1 (HO-1)
Interleukin-1 beta affects cyclooxygenase-2 expression and cartilage metabolism in mandibular condyle
Keywords: Cyclooxygenase-2 (COX-2); Interleukin-1 beta (IL-1β); Prostaglandin E2 (PGE2); Temporomandibular joint (TMJ); Chondrocytes;
15-Hydroxyprostaglandin dehydrogenase as a novel molecular target for cancer chemoprevention and therapy
Keywords: 15-Hydroxyprostaglandin dehydrogenase (15-PGDH); Tumor suppressor; Chemoprevention; Cyclooxygenase-2 (COX-2); Prostaglandin E2 (PGE2)
The aromatic volatile organic compounds toluene, benzene and styrene induce COX-2 and prostaglandins in human lung epithelial cells via oxidative stress and p38 MAPK activation
Keywords: Volatile organic compound (VOC); Lung epithelial cells; Cyclooxygenase-2 (COX-2); Oxidative stress; p38 MAPK;
Inhibitory effect of glycoprotein isolated from Opuntia ficus-indica var. saboten MAKINO on activities of allergy-mediators in compound 48/80-stimulated mast cells
Keywords: Histamine; Interleukin-4 (IL-4); Nuclear factor kappa B (NF-κB); Arachidonic acid; Extracellular signal-regulated kinase (ERK 1/2); Cyclooxygenase-2 (COX-2)
Anti-inflammatory effect of lucidone in mice via inhibition of NF-κB/MAP kinase pathway
Keywords: Lucidone; Lindera erythrocarpa; Inducible nitric oxide synthase (iNOS); Cyclooxygenase-2 (COX-2); Nuclear factor-κB (NF-κB); Adaptor protein-1 (AP-1)
Prolonged Endochondral Bone Healing in Senescence is Shortened by Low-Intensity Pulsed Ultrasound in a Manner Dependent on COX-2
Keywords: Cyclooxygenase-2 (COX-2); Prostaglandin E2 (PGE2); Fracture healing; Low-intensity pulsed ultrasound (LIPUS);
Malignant salivary gland tumors and cyclo-oxygenase-2: A histopathological and immunohistochemical analysis with implications on histogenesis
Keywords: Cyclooxygenase-2 (cox-2); Oral cancer; Salivary gland; Malignant salivary gland tumors; Histogenesis; Molecular markers
Cyclooxygenase-2 is involved in oxidative damage and alpha-synuclein accumulation in dopaminergic cells
Keywords: Cyclooxygenase-2 (COX-2); Dopamine; Oxidative stress; α-Synuclein; Parkinson's disease
The time-dependent expressions of IL-1β, COX-2, MCP-1 mRNA in skin wounds of rabbits
Keywords: Wound age estimation; Interleukin-1β (IL-1β); Cyclooxygenase-2 (COX-2); Monocyte chemotactic protein-1 (MCP-1); Real-time fluorescent quantitative PCR
Photo-crosslinking of proteins in intact cells reveals a dimeric structure of cyclooxygenase-2 and an inhibitor-sensitive oligomeric structure of microsomal prostaglandin E2 synthase-1
Keywords: Microsomal prostaglandin E2 synthase-1 (mPGES-1); Cyclooxygenase-2 (COX-2); Prostaglandins; Protein photo-crosslinking; Photo-methionine; Selective mPGES-1 inhibitor
The adjuvant effects of Antrodia Camphorata extracts combined with anti-tumor agents on multidrug resistant human hepatoma cells
Keywords: Antrodia camphorata; Hepatoma; Multidrug resistance (MDR); Cyclooxygenase-2 (COX-2); Anti-tumor agents
COX-2 from the injury milieu is critical for the initiation of periosteal progenitor cell mediated bone healing
Keywords: Cyclooxygenase-2 (COX-2); Periosteum; Bone graft transplantation; Bone repair; Periosteal progenitors
Lysophosphatidic acid upregulates vascular endothelial growth factor-C and tube formation in human endothelial cells through LPA1/3, COX-2, and NF-κB activation- and EGFR transactivation-dependent mechanisms
Keywords: Lysophosphatidic acid (LPA); Vascular endothelial growth factor-C (VEGF-C); Cyclooxygenase-2 (COX-2); Nuclear factor kappaB (NF-κB); Endothelial growth factor receptor (EGFR) transactivation; Endothelial cells
Pharmacological nature of nicotine-induced contraction in the rat basilar artery: Involvement of arachidonic acid metabolites
Keywords: Rat basilar artery; Nicotine; Contraction; Endothelium; Cyclooxygenase-2 (COX-2); Arachidonic acid metabolite
Suppression of IL-1β-induced COX-2 expression by trichostatin A (TSA) in human endometrial stromal cells
Keywords: Cyclooxygenase-2 (COX-2); Endometrial; Endometriosis; Histone deacetylase inhibitor; IL-1β; Stromal cells
Chemopreventive effects of sarcophine-diol on skin tumor development in CD-1 mice
Keywords: Chemoprevention; Sarcophine-diol; Apoptosis; Cyclooxygenase-2 (COX-2); Skin cancer;
Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii
Keywords: Tripterygium wilfordii; Celastraceae; Anti-inflammation; Immunosuppression; Tetrahydrofuran lignan; Cyclooxygenase-2 (COX-2); Inducible nitric oxide synthase (iNOS); Interleukin-1β (IL-1β); Polymerase chain reaction (PCR); Triptolide; Tripdiolide;
Temporospatial patterns of COX-2 expression and pyramidal cell degeneration in the rat hippocampus after trimethyltin administration
Keywords: Cyclooxygenase-2 (COX-2); Trimethyltin (TMT); CA1; CA3; Neuronal degeneration; Plasma corticosterone concentration
Role of cyclooxygenase-2 in tetrahydrobiopterin-induced dopamine oxidation
Keywords: Cyclooxygenase-2 (COX-2); Dopamine; Oxidative stress; Tetrahydrobiopterin (BH4); Parkinson's disease;