Keywords: A; adenine; A549; adenocarcinomic human alveolar basal epithelial cells; AKR1C3; Aldo_Keto Reductase; BaP; Benzo(a)pyrene; C; cytosine; CI; Confidence interval; CO; carbon monoxide; CXCL 13; motif chemokine ligand 13; CYP1B1; cytochrome P450 1B1; DKK2; Di
مقالات ISI (ترجمه نشده)
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Keywords: β-CTF; APP beta C-terminal fragment; AA; arachidonic acid; AD; Alzheimer's Disease; APP; Amyloid Precursor Protein; BACE1; beta secretase 1; CE; esterified cholesterol; CHOL; free cholesterol; CNS; central nervous system; COX-2; cyclooxygenase-2; Cyp1b
Keywords: Chronic rhinosinusitis with nasal polyps; aryl hydrocarbon receptor (AhR); kynurenine; mast cell; calmodulin-dependent protein kinase II (CaMKII); AhR; Aryl hydrocarbon receptor; BMMCs; Bone marrow-derived mast cells; CaMKII; Calmodulin-dependent protei
Keywords: E2; 17β-estradiol; 2-OH-E2; 2-hydroxy-17β-estradiol; 4-OH-E2; 4-hydroxy-17β-estradiol; CYP1B1; cytochrome P450 (CYP) 1B1; Î6-E1; Î6-estrone; IC50; 50% inhibition; Fisetin (PubChem CID: 5281614); 17β-Estradiol (PubChem CID: 5757); Flavone (PubChem CI
Keywords: BMI; Body Mass Index; CI; Confidence intervals; COMT; Catechol-O-methyltransferase; CYP17; 17α-hydroxylase and 17, 20-lyase; CYP19; Aromatase; CYP1A1; Cytochrome P450 1A1; CYP1B1; Cytochrome P450 1B1; E2; Estradiol; Ile; Isoleucine; Leu; Leucine; Met; Me
Keywords: CC16; Clara cell secretory protein 16; COPD; chronic obstructive pulmonary disease; CXCL1; C-X-C motif chemokine ligand 1; CYP1A1; cytochrome P450 family 1 subfamily A member 1; CYP1B1; cytochrome P450 family 1 subfamily B member 1; EPA; Environmental Pro
Keywords: ACES; Aravind Comprehensive Eye Survey; ACG; Angle Closure Glaucoma; AD; Autosomal Dominant; APEDS; Andhra Pradesh Eye Disease Study; AR; Autosomal Recessive; ATOH7; Atonal Homolog 7; BACES; British Asian Community Eye Study; CARD10; Caspase Recruitment D
Keywords: AhR; aryl hydrocarbon receptor; AhRR; aryl hydrocarbon receptor repressor; ARNT; AhR nuclear translocator; B[a]P; Benzo[a]Pyren; Ct; total carbon; CYP1A1; cytochrome P4501A1; CYP1B1; cytochrome P4501B1; s; double strand breaks; DL; detection limit; LDH; l
Keywords: Alb; albumin; CYP1A1; cytochrome P450 1A1; CYP1B1; cytochrome P450 1B1; E2; 17β-estradiol; E2-2,3-Q; 17β-estradiol-2,3-quinone; E2-3,4-Q; 17β-estradiol-3,4-quinone; E2-2,3-Q-1-S-NAC and E2-2,3-Q-4-S-NAC; reaction products of E2-2,3-Q with N-acetyl-l-cy
Keywords: glaucoma; primary open-angle glaucoma; association study; polymorphisms; CYP1B1;
Keywords: Protein adducts; Estrogen; Quinones; Biomarker; Alb; albumin; CYP1A1; cytochrome P450 1A1; CYP1B1; cytochrome P450 1B1; E2; 17β-estradiol; E2-2,3-Q; 17β-estradiol-2,3-quinone; E2-3,4-Q; 17β-estradiol-3,4-quinone; E2-2,3-Q-1-S-NAC and E2-2,3-Q-4-S-NAC;
Keywords: AHR; aryl hydrocarbon receptor; AHR-KO; aryl hydrocarbon receptor knockout; Ahrr; aryl hydrocarbon receptor repressor; AIP; aryl hydrocarbon receptor interacting protein; ALB; serum albumin; ALP; alkaline phosphatase; ALT; alanine aminotransferase; ARNT;
Is it the time to study air pollution effects under environmental conditions? A case study to support the shift of in vitro toxicology from the bench to the field
Keywords: Air pollution; In vitro environmental exposure; Air liquid interface; Ultrafine particles toxicology; Secondary aerosol; Correlation PM-Composition and biological effects; AAE; Absorption Ã
ngström Angstrom Exponent; BC; black carbon; Dmed; median diame
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
Cancer chemoprevention revisited: Cytochrome P450 family 1B1 as a target in the tumor and the microenvironment
Keywords: Chemoprevention; Angioprevention; Cancer; Microenvironment; Inflammation; Angiogenesis; Phytochemicals; CYP1 enzymes; CYP1B1;
Glycyrrhiza glabra extract and quercetin reverses cisplatin resistance in triple-negative MDA-MB-468 breast cancer cells via inhibition of cytochrome P450 1B1 enzyme
Keywords: Cisplatin-resistance; CYP1B1; Glycyrrhiza glabra; Quercetin; Glabrol; MDA-MB-468 cells;
Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance
Keywords: Heterocyclic chalcones; AhR antagonism; CYP1A1; Chemoprevention; CYP1B1; Cisplatin chemo-resistance;
Decreased expression of cytochrome p450 1B1 in non-small cell lung cancer
Keywords: Lung cancer; CYP1B1; Smoking; NSCLC;
AHR toxicity and signaling: Role of TIPARP and ADP-ribosylation
Keywords: Aryl hydrocarbon receptor; 2,3,7,8-Tretrachlorodibenzo-p-dioxin; ADP-ribosylation; TCDD-inducible poly-ADP-ribose polymerase; AHR; aryl hydrocarbon receptor; AHRE; AHR response element; ARH; ADP-ribosyl hydrolases; ARNT; AHR nuclear translocator; ARTD; AD
Transcriptome analysis of airborne PM2.5-induced detrimental effects on human keratinocytes
Keywords: ADSP; Asian dust storm particles; CYP1A1; cytochrome P450, family 1, subfamily A, polypeptide 1; CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1; DEG; differentially expressed gene; EDS; energy dispersive X-ray spectrometry; ELISA; enzyme-li
Inhibitors of cytochrome P450 (CYP) 1B1
Keywords: Cytochrome; CYP1B1; Enzyme; Inhibitor; Anticancer agent;
Elimination of dysfunctional mitochondria through mitophagy suppresses benzo[a]pyrene-induced apoptosis
Keywords: Benzo[a]pyrene; Mitophagy; Apoptosis; ATP depletion; CYP1B1; MnSOD;
Cyp1b1 deletion and retinol deficiency coordinately suppress mouse liver lipogenic genes and hepcidin expression during post-natal development
Keywords: Vitamin A; Vitamin A deficiency; Cytochrome P450 1b1; Hepcidin; Lipogenesis; BD; standard breeder diet; Cyp1b1; cytochrome P450 1b1; DIO; diet-induced obesity; E; embryonic day; GVAD; gestational initiation of vitamin A deficient diet; HFD; high fat diet;
ITE Suppresses Angiogenic Responses in Human Artery and Vein Endothelial Cells: Differential Roles of AhR
Keywords: AhR; Aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; CYP1A1; cytochrome P450 family 1 member A1; CYP1B1; cytochrome P450 family 1 member B1; BM; basal RPMI 1640 media; CGM; complete growth medium; FBS; fetal bovine serum; FGF2; fibroblast growth factor
Quinazoline derivatives as selective CYP1B1 inhibitors
Keywords: Quinazoline; CYP1B1; Cancer chemoprevention; Sacchrosomes; Selective CYP1B1 inhibitor;
DNA methylation in lung tissues of mouse offspring exposed in utero to polycyclic aromatic hydrocarbons
Keywords: Polycyclic aromatic hydrocarbon; Lung cancer; DNA methylation; Transplacental; Epigenetics; Methylated DNA immunoprecipitation; AdjBaP; lung tissue adjacent to a tumor from BaP-exposed offspring; AdjDBC; lung tissue adjacent to a tumor from BaP-exposed of
Targeting cytochrome P450 (CYP) 1B1 with steroid derivatives
Keywords: CYP1B1; Enzyme; Inhibitor; Screening; Steroid;
MicroRNA-187-5p suppresses cancer cell progression in non-small cell lung cancer (NSCLC) through down-regulation of CYP1B1
Keywords: hsa-miRNA-187-5p (miR-187-5p); CYP1B1; Non-small cell lung cancer (NSCLC); Proliferation; Apoptosis;
Triclosan activates aryl hydrocarbon receptor (AhR)-dependent apoptosis and affects Cyp1a1 and Cyp1b1 expression in mouse neocortical neurons
Keywords: Triclosan; AhR; Cyp1a1; Cyp1b1; Apoptosis; Neuron;
Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα
Keywords: Cyp1b1; Obesity; Liver; HNF4α; PPARα; Growth hormone
Short communicationHomozygous p.G61E mutation in a consanguineous Pakistani family with co-existence of juvenile-onset open angle glaucoma and primary congenital glaucoma
Keywords: POAG; primary open angle glaucoma; JOAG; juvenile open angle glaucoma; PCG; primary congenital glaucoma; CYP1B1; cytochrome p450 1B1 gene; IOP; intraocular pressure; CYP1B1; JOAG; PCG; G61E; Pakistan;
Interethnic differences of cytochrome P450 gene polymorphisms may influence outcome of taxane therapy in Roma and Hungarian populations
Keywords: CYP1B1; CYP2C8; CYP3A5; Roma; Hungarian; Taxane; Metabolism; Polymorphism
Stability of the aryl hydrocarbon receptor and its regulated genes in the low activity variant of Hepa-1 cell line
Keywords: PAH; polycyclic aromatic hydrocarbon; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocating protein; AHH; aryl hydrocarbon hydroxylase; Hepa-1; mouse hepatoma cell line; WT; wild type; LA1; low AHH-activity, class I variant
Aryl hydrocarbon receptor regulates CYP1B1 but not ABCB1 and ABCG2 in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure
Keywords: Aryl hydrocarbon receptor; CYP1B1; ATP-binding cassette transporters; Blood–brain barrier; hCMEC/D3
Cytochrome P1B1 (CYP1B1) polymorphisms and cancer risk: A meta-analysis of 52 studies
Keywords: Cancer; Polymorphism; CYP1B1; Meta-analysis;
Differential inhibition of CYP1-catalyzed regioselective hydroxylation of estradiol by berberine and its oxidative metabolites
Keywords: Estradiol; CYP1B1; Variants; Berberine; Thalifendine; Demethyleneberberine
Loss of sirtuin 1 (SIRT1) disrupts skin barrier integrity and sensitizes mice to epicutaneous allergen challenge
Keywords: Sirtuin 1 (SIRT1); skin barrier; filaggrin; AD; Atopic dermatitis; AhR; Aryl hydrocarbon receptor; ARNT; Aryl hydrocarbon receptor nuclear translocator; BaP; Benzo(a)pyrene; cHet; Epidermis-specific heterozygous SIRT1 deletion; cKO; Epidermis-specific hom
COMT 158G/A and CYP1B1 432C/G polymorphisms increase the risk of endometriosis and adenomyosis: a meta-analysis
Keywords: Meta-analysis; CYP1B1; Endometriosis; Adenomyosis;
Preferential expression of cytochrome CYP CYP2R1 but not CYP1B1 in human cord blood hematopoietic stem and progenitor cells
Keywords: Cytochrome P450; CYP2R1; CYP1B1; CD34+; Hematopoietic stem cells; Gene expressionbp, base pair; Ct, threshold cycle; CBHSPCs, cord blood HSPCs; FACS, fluorescence-activated cell sorting; HSPCs, hematopoietic stem and early progenitor cells; kbp, kilobase
Combining metabolomic analysis and microarray gene expression analysis in the characterization of the medicinal plant Chelidonium majus L
Keywords: Chelidonii herba; Herbal safety; Gene expression profiling; 1H-NMR fingerprint; IPA; Ingenuity pathway analysis; PCA; Principal component analysis; qRT-PCR; quantitative real-time PCR; AhRR; Aryl-hydrocarbon receptor repressor; AKR1B10; Aldo-keto reductas
Leptin induces CYP1B1 expression in MCF-7 cells through ligand-independent activation of the ERα pathway
Keywords: Leptin; CYP1B1; ERα; ERE
CYP1A1 and CYP1B1-Mediated Biotransformation of the Antitrypanosomal Methamidoxime Prodrug DB844 Forms Novel Metabolites Through Intramolecular Rearrangement
Keywords: CYP1A1; CYP1B1; cytochrome P450; intramolecular rearrangement; drug metabolism; prodrugs; human African trypanosomiasis; nitric oxide; CID, collision-induced dissociation; CNS, central nervous system; CYP, cytochrome P450; HAT, human African trypanosomias
Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone
Keywords: 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d
Modulation of aryl hydrocarbon receptor target genes in circulating lymphocytes from dairy cows bred in a dioxin-like PCB contaminated area
Keywords: PCDDs; polychlorodibenzo-p-dioxins; PCDFs; polychlorodibenzofurans; PCBs; polychlorobiphenyls; DL; dioxin-like; AHR; aryl hydrocarbon receptor; ARNT; AHR nuclear translocator; XREs; xenobiotic-response elements; AHRR; AHR repressor; TCDD; 2,3,7,8 tetrachl
Diphenylarsinic acid, a chemical warfare-related neurotoxicant, promotes liver carcinogenesis via activation of aryl hydrocarbon receptor signaling and consequent induction of oxidative DAN damage in rats
Keywords: AhR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; CYP; cytochrome P450; COX-2; cyclooxygenase-2; DEN; diethylnitrosamine; DMBA; 7,12-dimethylbenz[a]anthracene; DPAA; diphenylarsinic acid; GST-P positive foci; glutathione S-transferase placental form
Inflammatory mediators accelerate metabolism of benzo[a]pyrene in rat alveolar type II cells: The role of enhanced cytochrome P450 1B1 expression
Keywords: Inflammation; CYP1B1; Polycyclic aromatic hydrocarbons; Metabolism; DNA adducts;
Inhibition of CYP1 by berberine, palmatine, and jatrorrhizine: Selectivity, kinetic characterization, and molecular modeling
Keywords: AHH; benzo(a)pyrene hydroxylase; P450, CYP; cytochrome P450; ECOD; 7-ethoxycoumarin O-deethylation; EROD; 7-ethoxyresorufin O-deethylation; MROD; 7-methoxyresorufin O-demethylation; Berberine; CYP1B1; Selective inhibition;
Mercury modulates the cytochrome P450 1a1, 1a2 and 1b1 in C57BL/6J mice: in vivo and in vitro studies
Keywords: AhR, aryl hydrocarbon receptor; Hg2 +, mercury chloride; Cyp450s, cytochrome P450s; HO-1, heme oxygenase-1; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD); XRE, xenobiotic responsive elementAhR; Mercury; Cyp1a1; Cyp1a2; Cyp1b1; TCDD; C57BL/6J; Hepatocyt
Stimulation of mouse Cyp1b1 during adipogenesis: Characterization of promoter activation by the transcription factor Pax6
Keywords: Cyp1b1; Adipogenesis; Pax6; Sp1; PPARγ; Embryo fibroblast
Cloning and tissues expression of the pig CYP1B1 and CYP2J34
Keywords: CYP1B1; CYP2J34; Pig