Keywords: DBD، دامنه اتصال DNA; ACTH, adrenocorticotropic hormone; AP1, activator protein 1; CGA, chorionic gonadotrophin alpha subunit; DBD, DNA binding domain; EGR1, early growth response protein 1; e, embryonic day; FSH, follicle-stimulating hormone; FBE, forkhead binding element; FO
مقالات ISI DBD، دامنه اتصال DNA (ترجمه نشده)
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Liver X Receptor (LXR) in yellow catfish Pelteobagrus fulvidraco: Molecular characterization, mRNA tissue expression and transcriptional regulation by insulin in vivo and in vitro
Keywords: DBD، دامنه اتصال DNA; AF, activation function; BW, body weight; DBD, DNA binding domain; LBD, ligand binding domain; LXR, liver X receptor; LXRE, LXR responsive elements; ORF, open reading frame; SEM, standard error of means; UTR, untranslated regionsPelteobagrus fulvidraco; l
Fish IRF6 is a positive regulator of IFN expression and involved in both of the MyD88 and TBK1 pathways
Keywords: DBD، دامنه اتصال DNA; IRF6; Positive regulator; Interferon; TBK1; MyD88CPE, cytopathic effect; DBD, DNA binding domain; EPC, epithelioma papulosum cyprini; IAD, IRF association domain; IFN, interferon; IRF, Interferon regulatory factor; ISG, IFN-stimulated gene; ISRE, IFN-stim
Identification, classification, and expression profiles of heat shock transcription factors in tea plant (Camellia sinensis) under temperature stress
Keywords: DBD، دامنه اتصال DNA; AHA, activator motif; CTAD, C-terminal activation domains; DBD, DNA binding domain; HSF, heat shock transcription factor; HSP, heat shock protein; HSR, heat shock response; NES, nuclear export signal; NLS, nuclear localization signal domain; OD, oligomeri
Sulfide exposure results in enhanced sqr transcription through upregulating the expression and activation of HSF1 in echiuran worm Urechis unicinctus
Keywords: DBD، دامنه اتصال DNA; SQR, sulfidequinone oxidoreductase; HSF1, heat shock factor 1; DBD, DNA binding domain; HR, heptad repeats domain; HSE, heat shock element; PSU, practical salinity units; RACE, rapid amplification of cDNA ends; IPTG, isopropyl β-D-1-thiogalactopyranoside;
An evolutionary, structural and functional overview of the mammalian TEAD1 and TEAD2 transcription factors
Keywords: DBD، دامنه اتصال DNA; DBD, DNA binding domain; IAP, Inhibitor of Apoptosis Protein; LATS, Large Tumor Suppressor; MST, Mammalian Ste20-like Protein Kinase; TEA, transcriptional enhancer activator; TEAD, TEA domain; VGLL, Vestigial like; YAP, Yes-associated protein; YBD, YAP bi
Molecular characterization and analysis of the porcine NURR1 gene
Keywords: DBD، دامنه اتصال DNA; DNA methylation; NURR1; Parkinson's disease; Pig; SNP; Transcription factorCNS, central nervous system; DAN, dopaminergic neuron; DAT, dopamin transporter; DBD, DNA binding domain; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; NTD, N-terminal domain; P
A novel gain-of-function STAT1 mutation resulting in basal phosphorylation of STAT1 and increased distal IFN-γ-mediated responses in chronic mucocutaneous candidiasis
Keywords: DBD، دامنه اتصال DNA; CMC, chronic mucocutaneous candidiasis; STAT1, signal transducer and activator of transcription 1; P-STAT1, phosphorylated STAT1; GOF, gain-of-function; CCD, coiled-coil domain; DBD, DNA binding domain; IL, interleukin; IFN, interferon; IP-10, IFN-gamma-i
The estrogen receptor alpha nuclear localization sequence is critical for fulvestrant-induced degradation of the receptor
Keywords: DBD، دامنه اتصال DNA; Breast cancer; Degradation; Endocrine therapy; Estrogen receptor; Fulvestrant; Nuclear localization sequenceAF-1, activation function 1; AF-2, activation function 2; ChIP, Chromatin immunoprecipitation; DBD, DNA binding domain; DMSO, Dimethyl sulfoxide; D
Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding
Keywords: DBD، دامنه اتصال DNA; DBD, DNA binding domain; Hox, Homeobox gene; HMGB1, High mobility group B1; NMR, Nuclear magnetic resonance; ITC, Isothermal titration calorimetric; EMSA, Electrophoretic mobility shift assayNMR; Hox; Homeodomain; HMGB1; Transcription
Lysine Deacetylases Regulate the Heat Shock Response Including the Age-Associated Impairment of HSF1
Keywords: DBD، دامنه اتصال DNA; HSF1, heat shock factor 1; HSR, heat shock response; HSE, heat shock element; EMSA, electrophoretic mobility shift assay; DBD, DNA binding domain; RD, regulatory domain; AD, activation domain; MEF, mouse embryonic fibroblast; PD, population doubling; GR,
Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ
Keywords: DBD، دامنه اتصال DNA; 17β-E, 17β-estradiol; AR, androgen receptor; ARA55, AR interacting protein 55; C/EBP, CCAAT enhancer binding protein; DBD, DNA binding domain; DHT, dihydrotestosterone; IGF-I, insulin-like growth factor I; PAI, plasminogen activator inhibitor; PGE2, prost
Identification of an estrogen receptor gene in the natural freshwater snail Bithynia tentaculata
Keywords: DBD، دامنه اتصال DNA; DBD, DNA binding domain; EDCs, endocrine disrupting chemicals; EE2, ethinylestradiol; ER/er, the estrogen receptor; LBD, ligand binding domainEstrogen receptor; 17α-Ethinylestradiol; Mollusk; Bithynia
DptR2, a DeoR-type auto-regulator, is required for daptomycin production in Streptomyces roseosporus
Keywords: DBD، دامنه اتصال DNA; A, adenosine; bp, base pair(s); C, cytidine; cDNA, DNA complementary to RNA; DBD, DNA binding domain; DeoR, deoxyribose regulator; DNase, deoxyribonuclease; dNTP, deoxyribonucleoside triphosphate; egfp, enhanced green fluorescent protein; EMSA, electropho
Annotation of the Daphnia magna nuclear receptors: Comparison to Daphnia pulex
Keywords: DBD، دامنه اتصال DNA; NR, nuclear receptor; CDD, conserved domain database; DBD, DNA binding Domain; LBD, Ligand binding Domain; Pfam, Protein family; ML, Maximum Likelihood; EcR, Ecdysone Receptor; KNR, Knirp; THRL, Thyroid hormone receptor-like; RARL, Retinoid Acid Receptor-
A single amino acid change humanizes long-chain fatty acid binding and activation of mouse peroxisome proliferator-activated receptor α
Keywords: DBD، دامنه اتصال DNA; PPARα, peroxisome proliferator-activated receptor alpha; DBD, DNA binding domain; LBD, ligand binding domain; RXRα, retinoid X receptor alpha; LCFA, long-chain fatty acids; LCFA-CoA, long-chain fatty acyl-CoA; mPPARα, mouse PPARα; hPPARα, human PPARα; F27
Homodimerization propensity of the intrinsically disordered N-terminal domain of Ultraspiracle from Aedes aegypti
Keywords: DBD، دامنه اتصال DNA; NTD, N-terminal domain; DBD, DNA binding domain; LBD, ligand binding domain; 20E, 20-hydroxyecdysone; EcR, ecdysone receptor; RXR, retinoid X receptor; Usp, Ultraspiracle; HR38, hormone receptor 38; IDP, intrinsically disordered protein; EcR-NTD, N-termin
Role of Rev-erbα domains for transactivation of the connexin43 promoter with Sp1
Keywords: DBD، دامنه اتصال DNA; Cx43, connexin43; AB, A/B region; DBD, DNA binding domain; H, hinge region; LBD, ligand binding domain; ER, Estrogen ReceptorConnexin43; Nuclear receptor; Rev-erbα; Rev-erbβ; Sp1
Enteral calcium infusion used successfully as treatment for a patient with hereditary vitamin D resistant rickets (HVDRR) without alopecia: A novel mutation
Keywords: DBD، دامنه اتصال DNA; HVDRR, Hereditary vitamin D resistant rickets; VDR, Vitamin D receptor; DBD, DNA binding domain; LBD, Ligand binding domain; PTH, Parathyroid hormone; RXR, Retinoid X receptor; PICC, Peripherally inserted central catheter; IV, IntravenousHereditary vitami
Cyclin D1/Cdk4 increases the transcriptional activity of FOXM1c without phosphorylating FOXM1c
Keywords: DBD، دامنه اتصال DNA; aa, amino acid; Cdk, cyclin-dependent kinase; CKI, Cdk inhibitor; CMV, cytomegalovirus; DBD, DNA binding domain; dn, dominant-negative; FOXM1c, Forkhead box M1, splice variant c; GST, glutathione-S-transferase; HA, hemagglutinin; HSV, herpes simplex virus
Structure and function of the DNA ligases encoded by the mammalian LIG3 gene
Keywords: DBD، دامنه اتصال DNA; BRCT, breast cancer susceptibility protein 1-related C-terminal; DBD, DNA binding domain; DNA PK, DNA-dependent protein kinase; DSB, DNA double-strand break; LIG, DNA ligase encoding gene; MLS, mitochondrial leader sequence; NEIL, Nei endonoclease VIII-li
Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in Zebrafish (Danio rerio)
Keywords: DBD، دامنه اتصال DNA; ABC transporters, ATP-binding cassette transporters; ARNT2, aryl hydrocarbon receptor nuclear translocator; CAR, constitutive androstane receptor; CLO, clotrimazole; CYP, cytochrome P450; DBD, DNA binding domain; DMSO, dimethylsulfoxide; EF1α, elongation
Epigenomic regulation of bile acid metabolism: Emerging role of transcriptional cofactors
Keywords: DBD، دامنه اتصال DNA; FXR, farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptor; DBD, DNA binding domain; LBD, ligand binding domain; GPCR, G-protein coupled receptor; GLP-1, glucagon-like peptide 1; ChIP, chromatin immunoprecipitation; Cyp7a1, chol
Understanding stress-effects in the brain via transcriptional signal transduction pathways
Keywords: DBD، دامنه اتصال DNA; AF-1, activation function-1; AF-2, activation function 2; cKO, conditional knockout; CRTCs, CREB-regulated transcriptional coregulators; DBD, DNA binding domain; ER, estrogen receptor; GR, glucocorticoid receptor; GREs, glucocorticoid response elements; H
Allosteric Controls of Nuclear Receptor Function in the Regulation of Transcription
Keywords: DBD، دامنه اتصال DNA; DBD, DNA binding domain; LBD, ligand binding domain; RE, response element; RID, receptor interacting domain; GRE, GR binding sitenuclear receptors; allosteric regulation
FoxA1 corrupts the antiandrogenic effect of bicalutamide but only weakly attenuates the effect of MDV3100 (Enzalutamide™)
Keywords: DBD، دامنه اتصال DNA; AR, androgen receptor; ARE(s), androgen response element(s); BIC, bicalutamide; bp, basepair; DBD, DNA binding domain; DMS, dimethylsulphate; DHSs, DNase I hypersensitive sites; DNase I, deoxyribonuclease I; ER, estrogen receptor; FoxA1, forkhead box tran
Headful DNA packaging: Bacteriophage SPP1 as a model system
Keywords: DBD، دامنه اتصال DNA; DBD, DNA binding domain; dsDNA, double-stranded DNA; bp, base pairs; CTD, C-terminal domain; gpx, gene product X; HTH, helix-turn-helix domain; LT, large terminase subunit; PL1, late promoter 1; PL2, late promoter 2; pacC, gp2 cleavage subsite; pacL, non-
Multiple structurally distinct ERα mRNA variants in zebrafish are differentially expressed by tissue type, stage of development and estrogen exposure
Keywords: DBD، دامنه اتصال DNA; AF, activation function; BPA, bisphenol A; DBD, DNA binding domain; DES, diethylstilbestrol; DMSO, dimethyl sulfoxide; E2, 17β-estradiol; EDC, endocrine disrupting chemicals; ER, estrogen receptor; hpf, hours post fertilization; LBD, ligand binding domain
Intrinsically disordered regions of p53 family are highly diversified in evolution
Keywords: DBD، دامنه اتصال DNA; ASA, solvent accessible surface area; CDF, cumulative distribution function; CH, charge-hydropathy; CTD, C-terminal domain; DBD, DNA binding domain; ER, endoplasmic reticulum; IDP, intrinsically disordered protein; IDPR, intrinsically disordered protein r
Monoubiquitination-dependent chromatin loading of FancD2 in silkworms, a species lacking the FA core complex
Keywords: DBD، دامنه اتصال DNA; FA, Fanconi anemia; MMC, mitomycin C; ICL, DNA interstrand cross-link; NLS, nuclear localization signal; RACE, rapid amplification of cDNA ends; dsRNA, double-stranded RNA; DBD, DNA binding domain; AD, transcriptional activation domain; UAS, GAL4 upstream
Expression of a dominant negative estrogen receptor alpha variant in transgenic mice accelerates uterine cancer induced by the potent estrogen diethylstilbestrol
Keywords: DBD، دامنه اتصال DNA; αERKO, estrogen receptor alpha knockout; DES, diethylstilbestrol; DBD, DNA binding domain; ERα, estrogen receptor alpha; ERβ, estrogen receptor beta; ERE, estrogen response element; PR, progesterone receptor; WT, wild-typeDiethylstilbestrol; Dominant nega
Estrogen receptor dependent gene expression by osteoblasts – Direct, indirect, circumspect, and speculative effects
Keywords: DBD، دامنه اتصال DNA; ER, estrogen receptor; AF-1, activation function 1; DBD, DNA binding domain; ERE, estrogen response element; LBD, ligand binding domain; AF-2, activation function 2; GPCR, G protein coupled receptor; GPER, G protein coupled estrogen receptor; ERR, estroge
FoxA1 and glucocorticoid receptor crosstalk via histone H4K16 acetylation at a hormone regulated enhancer
Keywords: DBD، دامنه اتصال DNA; au, arbitrary units; CR, conserved region; DBD, DNA binding domain; DMS, dimethylsulphate; DNase I, deoxyribonuclease I; FoxA1, the forkhead box transcription factor FoxA1; GR, glucocorticoid receptor; LTR, long terminal repeat; MMTV, mouse mammary tumor
CIDEA interacts with liver X receptors in white fat cells
Keywords: DBD، دامنه اتصال DNA; CIDEA, cell death-inducing DNA fragmentation factor alpha-like effector A; DBD, DNA binding domain; GFP, green fluorescence protein; GST, glutathione S-transferase; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor γNuclear receptor
Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modifications
Keywords: DBD، دامنه اتصال DNA; FXR, Farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptors; AF-1, activation function 1; AF-2, activation function 2; DBD, DNA binding domain; LBD, ligand binding domain; CDCA, chenodeoxycholic acid; FXRE, FXR response element;
β-Catenin independent cross-control between the estradiol and Wnt pathways in osteoblasts
Keywords: DBD، دامنه اتصال DNA; DBD, DNA binding domain; GSK, glycogen synthase kinase; RE, response element; RT-PCR, real time polymerase chain reaction; Runx, runt homology domain transcription factor; TCF, T cell factor; WAg, Wnt pathway agonist17βE; Estrogen receptor; TCF-4; Runx2;
Structural and Thermodynamic Signatures of DNA Recognition by Mycobacterium tuberculosis DnaA
Keywords: DBD، دامنه اتصال DNA; MtDnaA, Mycobacterium tuberculosis DnaA; DBD, DNA binding domain; SPR, surface plasmon resonance; ITC, isothermal titration calorimetry; PDB, Protein Data Bankprotein–DNA interactions; ITC; tuberculosis; replication initiation; DnaA
Crosstalk and DC-SCRIPT: Expanding nuclear receptor modulation
Keywords: DBD، دامنه اتصال DNA; ECM, extracellular matrix; NR, nuclear receptor; DBD, DNA binding domain; ER, Estrogen Receptor; PR, Progesterone Receptor; AR, Androgen Receptor; GR, Glucocorticoid Receptor; RXR, Retinoid X Receptor; RAR, Retinoic Acid Receptor; PPAR, peroxisome prolife
3rd US–EU Workshop: Systems level understanding of DNA damage responses
Keywords: DBD، دامنه اتصال DNA; AT, ataxia telangiectasia; ATM, Ataxia telangiectasia mutated; ATR, ataxia telangiectasia related; CC, catalytic core; DBD, DNA binding domain; DDR, DNA damage response; DSB, double strand break; HR, homologous recombination; HRD, HR-defective; MEF, mouse
Nuclear receptor coregulators as a new paradigm for therapeutic targeting
Keywords: DBD، دامنه اتصال DNA; NR, nuclear hormone receptor; LBD, ligand binding domain; DBD, DNA binding domain; SERM, selective estrogen receptor modulator; SRC, steroid receptor coactivator; ACTR, activator for receptors; AIB1, amplified in breast cancer 1; TIF2, transcriptional int
Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation
Keywords: DBD، دامنه اتصال DNA; DAPI, 4′,6-diamidino-2-phenylindole; DBD, DNA binding domain; DMEM, Dulbecco's modified eagles medium; EGFP, enhanced green fluorescent protein; KO, knock out; Mdm2, mouse double minute 2; NEDD8, neural precursor cell expressed developmentally down-regula
Folding of Tetrameric p53: Oligomerization and Tumorigenic Mutations Induce Misfolding and Loss of Function
Keywords: DBD، دامنه اتصال DNA; TD, tetramerization domain; DBD, DNA binding domain; WT, wild type; EMSA, electrophoretic mobility shift assaycancer; aggregation; protein stability; DBD; tetramerization
Protein–Protein Interactions Between σ70 Region 4 of RNA Polymerase and Escherichia coli SoxS, a Transcription Activator That Functions by the Prerecruitment Mechanism: Evidence for “Off-DNA” and “On-DNA” Interactions
Keywords: DBD، دامنه اتصال DNA; RNAP, RNA polymerase; σ70 R4, region 4 of σ70; CAP, catabolite activator protein; αCTD, C-terminal domain of the RNAP α subunit; Y2H, yeast two-hybrid; AIA, affinity immobilization assay; his6, hexa-histidine; DBD, DNA binding domain; AD, activation domai
Specific involvement of glycogen synthase kinase-3 in the function and activity of sex steroid hormone receptors reveals the complexity of their regulation
Keywords: DBD، دامنه اتصال DNA; AR, androgen receptor; Cdk, cyclin-dependent kinase; DBD, DNA binding domain; ER, estrogen receptor; EGFR, epidermal growth factor receptor; GSK-3, glycogen synthase kinase-3; GST, glutathione S-transferase; IGF, insulin-like growth factor; IGF-IR, type I
p53 mutations as fingerprints for aristolochic acid – an environmental carcinogen in endemic (Balkan) nephropathy
Keywords: DBD، دامنه اتصال DNA; AA, aristolochic acid; EN, endemic nephropathy; DBD, DNA binding domain; AAN, aristolochic acid-associated nephropathy; TCC, transitional cell carcinoma; OTA, ocratoxin A; IACR, International Agency for Research on CancerEnvironmental carcinogen; Aristolo
Gtr1p differentially associates with Gtr2p and Ego1p
Keywords: DBD، دامنه اتصال DNA; TOR, target of rapamycin; SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis; GTP, Guanosine Triphosphate; GDP, Guanosine Diphosphate; DBD, DNA binding domain; AD, Activation Domain; HA, hemagglutinin; Mr, Molecular weight; PDB, Protein D
Orthologues of the Drosophila melanogaster E75 molting control gene in the filarial parasites Brugia malayi and Dirofilaria immitis
Keywords: DBD، دامنه اتصال DNA; NR, nuclear receptor; DBD, DNA binding domain; LBD, ligand binding domain; RT-PCR, reverse transcription-polymerase chain reaction; PCR, polymerase chain reaction; CTE, carboxy terminal extension; EMSA, electrophoretic mobility shift assay; AF-2 AD, activ
Phosphorylation of estrogen receptor alpha, serine residue 305 enhances activity
Keywords: DBD، دامنه اتصال DNA; AF, activation function; AR, androgen receptor; BrdU, bromo-deoxyuridine; CDT, charcoal dextran treated; ChIP, chromatin immunoprecipitation; CMV, cytomegalovirus; DBD, DNA binding domain; ER, estrogen receptor; ERE, estrogen response element; E2, estradi
Integration of progesterone receptor action with rapid signaling events in breast cancer models
Keywords: DBD، دامنه اتصال DNA; AF, activation function; AR, androgen receptor; CDK2, cyclin-dependent protein kinase 2; DBD, DNA binding domain; EGF, epidermal growth factor; ER, estrogen receptor; H, hinge; HBD, hormone binding domain; Hsp, heat shock protein; MAPK, p42/p44 mitogen ac
Gene structures and promoter characteristics of interferon regulatory factor 1 (IRF-1), IRF-2 and IRF-7 from snakehead Channa argus
Keywords: DBD، دامنه اتصال DNA; IFN, interferon; IRF, interferon regulatory factor; ISG, interferon stimulated gene; STAT, signal transducer and activator of transcription; ORF, open reading frame; UTR, untranslated region; aa, amino acid; nt, nucleotide; DBD, DNA binding domain; IAD, I