Keywords: همبستگی Dbl; Actin dynamics; Rho GTPases; dendritic spines; postsynapse; Abi-1; Abelson interacting protein 1; Abp1; actin binding protein 1; ACTN4; α-actinin-4; ADF; actin-depolymerizing factor; ADHD; attention deficit/hyperactivity disorder; ADNP; activity-dependen
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Direct regulation of p190RhoGEF by activated Rho and Rac GTPases
Keywords: همبستگی Dbl; RhoGEF; Rho guanine nucleotide exchange factors; RhoGAP; GTPase-activating proteins; DH; Dbl homology; PH; pleckstrin homology; PRG; PDZRhoGEF; TEV; Tobacco Etch Virus; His6; hexahistidine peptide; GST; glutathione S-transferase; ITC; isothermal titration
The C1 domain of Vav3, a novel potential therapeutic target
Keywords: همبستگی Dbl; DAG; diacylglycerol; PKC; protein kinase C; GEF; guanine nucleotide exchange factor; PMA; phorbol 12-myristate 13-acetate; PDBu; phorbol 12,13-dibutyrate; CH domain; calponin homology domain; AD; acidic domain; DH; Dbl homology; PH; Pleckstrin homology; S
PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway
Keywords: همبستگی Dbl; DH; dbl homology; DHR; dock homology region; DMEM; Dulbecco's modified Eagle's medium; Eph; ephrin receptor; FBS; fetal bovine serum; GAP; GTPase activating protein; G-protein; guanosine triphosphate-binding protein; GPCR; heterotrimeric G-protein-coupled
The guanine nucleotide exchange factor Tiam1: A Janus-faced molecule in cellular signaling
Keywords: همبستگی Dbl; DH; Dbl homology; JIP/IB2; c-Jun N-terminal kinase-interacting protein/islet-brain 2; GAP; GTPase-activating protein; GDP; guanosine diphosphate; GDI; guanine dissociation inhibitor; GEF; guanine nucleotide-exchange factor; GTP; guanosine triphosphate; PH
p63RhoGEF-mediated formation of a single polarized lamellipodium is required for chemotactic migration in breast carcinoma cells
Keywords: همبستگی Dbl; DH; Dbl homology; FCS; fetal calf serum; GEF; guanine nucleotide exchange factor; GST; glutathione S-transferase; PH; pleckstrin homology; RBD; Rho-binding domain; shRNA; short hairpin RNA; p63RhoGEF; RhoA; Rho-GEF; Cell migration; Lamellipodium; MDA-MB-2
Modification of p115RhoGEF Ser330 regulates its RhoGEF activity
Keywords: همبستگی Dbl; ATRA; All-trans retinoic acid; DH; Dbl homology; DMEM; Dulbecco's modified Eagle's medium; FBS; Fetal bovine serum; GAP; GTPase activating protein; HPLC-MS/MS; High pressure/tandem mass spectrometry; LARG; Leukemia-associated RhoGEF; LC/MS/MS; Liquid ch
Structural landscape of the proline-rich domain of Sos1 nucleotide exchange factor
Keywords: همبستگی Dbl; Abi1; Abl interactor 1; CD; Circular dichroism; Cdc25; Cell cycle division 25; DH; Dbl homology; DLS; Dynamic light scattering; EGFR; Epidermal growth factor receptor; Eps8; EGFR kinase substrate 8; Grb2; Growth factor receptor binder 2; GuHCl; Guanidine
CommentaryUnderstanding SOS (Son of Sevenless)
Keywords: همبستگی Dbl; AhR; aryl hydrocarbon receptor; Cdc 25; cell division cycle 25; CFC; cardio-facio-cutaneous syndrome; DH; Dbl homology; E3b1; Eps8 SH3 domain binding protein 1; Eps8; EGFR pathway substrate 8; ERK; extracellular signal-regulated protein kinase; Grb2; grow
Gαq allosterically activates and relieves autoinhibition of p63RhoGEF
Keywords: همبستگی Dbl; AF; Alexa Fluor 532; Dbs; Dbl's big sister; DH; Dbl homology; FCPIA; Flow cytometry protein interaction assay; FP; Fluorescence polarization; GFP; Green fluorescent protein; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; MFI; Me
Molecular basis for the substrate specificity of plant guanine nucleotide exchange factors for ROP
Keywords: همبستگی Dbl; At; Arabidopsis thaliana; Cdc42; cell division cycle 42; cDNA; complementary DNA; Dbl; diffuse B-cell lymphoma; DH; Dbl homology; G protein; guanine nucleotide binding protein; GDI; guanine nucleotide dissociation inhibitor; GEF; guanine nucleotide exchan
ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics
Keywords: همبستگی Dbl; ALS2CL; ALS2 carboxy-terminal like; MNDs; motor neuron diseases; GEF; guanine-nucleotide exchange factor; RLD; RCC1-like domain; DH; Dbl homology; PH; pleckstrin homology; VPS9; vacuolar protein sorting 9; MORN; membrane occupation and recognition nexus;
EhGEF2, a Dbl-RhoGEF from Entamoeba histolytica has atypical biochemical properties and participates in essential cellular processes
Keywords: همبستگی Dbl; GEF; guanine nucleotide exchange factor; DH; Dbl homology; PH; Pleckstrin homology; Arm; armadillo; PA; phosphatidic acid; Dbl proteins; Rho GTPases; EhGEF2; Entamoeba histolytica; Armadillo; Phosphatidic acid; Erythrophagocytosis; Proliferation; Chemotax
Role of guanine nucleotide exchange factor P-Rex-2b in sphingosine 1-phosphate-induced Rac1 activation and cell migration in endothelial cells
Keywords: همبستگی Dbl; P-Rex2b; GEF; Cell migration; Endothelial cell; HEK293T cell; Rac1; P-Rex2; PtdIns(3,4,5)P3-dependent Rac exchange factor 2; SRE.L; SRE-Luciferase reporter gene; S1P; spingosine-1 phosphate; GEF; guanine nucleotide exchange factor; PIP3; phosphatidylinosi
Multiple novel isoforms of Trio are expressed in the developing rat brain
Keywords: همبستگی Dbl; GEF; guanine nucleotide exchange factor; SH3; src homology 3; DH; Dbl homology; PH; Plekstrin homology; Ig; immunoglobulin; FN; fibronectin; GST; glutathione S-transferase; BLAT; BLAST-like alignment tool; EST; expressed sequence tag; kDa; kilo Dalton; PC
Entamoeba histolytica: inhibition of cellular functions by overexpression of EhGEF1, a novel Rho/Rac guanine nucleotide exchange factor
Keywords: همبستگی Dbl; Entamoeba histolytica; GEF; guanine nucleotide exchange factor; Dbl; diffuse B-cell lymphoma; mant-GDP; N-methylanthraniloyl-GDP; DH; Dbl homology; PH; pleckstrin homology; HSV; Herpes simplex virus glycoprotein D; GST; glutathione S-transferase;
Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains
Keywords: همبستگی Dbl; DH; dbl homology; FRET; fluorescence resonance energy transfer; GAP; GTPase-activating protein; GTPγS; guanosine 5â²-O-(3-thiotriphosphate); NHS; N-hydroxysuccinimide; PA; phosphatidic acid; PdZA; a chimeric protein consisting of the PH domain of PLC δ