Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs
Keywords: CBR; carbonyl reductase; SDR; short-chain dehydrogenase/reductase; CYP; cytochrome P450; AKR; aldo-keto reductase; DOX; doxorubicin; FA; fatty acid; ONE; 4-oxo-2-nonenal; 13h; 8-hydroxy-2-imino-2H-chromene-3-carboxylic acid (2-chlorophenyl)amide; DHRS4; d