Keywords: Ngb; neuroglobin; WHO; world health organization; NSCLC; non-small cell lung cancer; ER; estrogen receptor; HCC; hepatocellular carcinoma; MAPK; mitogen-activated protein kinase; NHA; normal human astrocyte; DMEM; Dulbecco minimum essential medium; FCS; f
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CCL5 deficiency rescues pulmonary vascular dysfunction, and reverses pulmonary hypertension via caveolin-1-dependent BMPR2 activation
Keywords: Chemokine CCL5/RANTES; BMPR2; Caveolin-1; Pulmonary artery smooth muscle cells; Artery endothelial cells apoptosis; Pulmonary vascular angiogenesis; PAH; pulmonary arterial hypertension; CCL5; chemokine (C-C motif) ligand 5; CCR1; chemokine receptor 1; CC
Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site
Keywords: Tubulin inhibitor; Colchicine binding site; Combretastatin A-4; Pyrazole analogue; Anti-tumour; Co-crystal structure; ABC; ATP-binding cassette; P-gp; P-glycoprotein; MRP; multidrug resistant proteins; CA-4; combretastatin A-4; SARs; structure-activity re
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents
Keywords: 1,4-Diaryl-2-azetidinone; Combretastatin A-4; Tubulin polymerization; Antitumor; SAR; structure-activity relationship; DABCO; 1,4-diazabicyclo[2.2.2]octane; TBAF; tetrabutylammonium fluoride; NMO; 4-methylmorpholine N-oxide; TBAB; tetrabutylammonium bromi
ANXA1Ac2-26 peptide, a possible therapeutic approach in inflammatory ocular diseases
Keywords: ACTB; Beta-actin; ALDH1A3; Aldehyde Dehydrogenase 1 Family, member A3; ANX; Annexin; ANXA1; Annexin A1; ANXA1Ac2-26; peptide of the ANXA1; ARPE-19; human retinal pigment epithelium cells; BRB; blood retinal barrier; CTGF; Connective Tissue Growth Factor
Identification and expression analysis of cellular and viral microRNAs in CyHV3-infected KCF-1 cells
Keywords: miRNA; microRNA; CyHV-3; Cyprinivirus 3; KHV; Koi Herpesvirus; KCF-1; Koi caudal fin cells-1; Nt; nucleotides; Bp; base pair; UTR; untranslated regions; LPS; lipopolysaccharide; VZV; varicella zoster virus; UVB; ultraviolet radiation b; DMEM; Dulbecco min
Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2
Keywords: GPR64; GPCR; G protein; Molecular pharmacology; Signal transduction; Peptide agonist; 7TM; seven-transmembrane spanning domain; CTF; C-terminal fragment; ECD; extracellular domain; eV; empty vector; DMEM; dulbecco minimum essential medium; ELISA; enzyme-l
Orally administered penicillamine is a potent inhibitor of neointimal and medial thickening in porcine saphenous vein-carotid artery interposition grafts
Keywords: 16; 23; 33; BrdU; bromodeoxyuridine; CABG; coronary artery bypass grafting; DMEM; Dulbecco minimum essential medium; FCS; fetal calf serum; PBS; phosphate-buffered saline solution; PCNA; proliferating cell nuclear antigen; VSMC; vascular smooth muscle cel