Keywords: AP; aminopeptidase; CP; carboxypeptidase; EP; endopeptidases; E-64; L-trans-epoxysuccinyl-leucylamide-4-guanidino-butane; FW; fresh weight; LAP; leucine aminopeptidases; MW; molecular weight; PAP; proline aminopeptidases; PMSF; phenylmethylsulfonylfluorid
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Keywords: α-MEM; (alpha-modified Eagle's minimum essential medium); Ail; (attachment-invasion locus); BPW; (buffered peptone water); E-64; (L-trans-epoxysuccinyl-L-leucylamido(4-guanidino)butane); LC-MS/MS; (liquid chromatography coupled to tandem mass spectrome
Keywords: Ethylene; Never ripe mutant; Programmed cell death; Reactive nitrogen forms; Reactive oxygen species; Salt stress; Tomato roots; ACC; 1-aminocyclopropane-1-carboxylic acid; ACO; ACC oxidase; ACS; ACC synthase; APF; Aminophenylfluorescein; AR; 10-Acetyl-3,
How proteolytic inhibitors interact with dentin on glass-fiber post luting over 6 months
Keywords: Bond strength; Chlorhexidine; E-64; EDTA; Root canal;
Proteases catalyzing vicilin cleavage in developing pea (Pisum sativum L.) seeds
Keywords: AEBSF; 4-(2-aminoethyl)benzenesulfonyl fluoride; DAI; days after imbibition; DTT; 1,4-dithiothreitol; E-64; N-[N-(L-3-transcarboxyirane-2-carbonyl)-l-leucyl]-agmatine; PCMPS; p-choromercuriphenylsulfonic acid; PSV; protein storage vacuole; Pisum sativum;
Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S
Keywords: Azapeptide; Bradykinin; Cathepsin; 1,2,3-triazole heterocycle; Protease; Protease inhibitor; Abz; o-aminobenzoic acid; Ahx; 6-aminohexanoic acid; AEBSF; 4-(2-aminoethyl) benzenesulfonyl fluoride hydrochloride; AMC; 7-amino-4-methyl coumarin; BK; bradykini
Establishment of a dietary exposure assay for evaluating the toxicity of insecticidal compounds to Apolygus lucorum (Hemiptera: Miridae)
Keywords: Genetically engineered crop; Cry protein; Environmental risk assessment; Apolygus lucorum; E-64;
Excessive expression and activity of cathepsin B in sheep cumulus cells compromises oocyte developmental competence
Keywords: Sheep oocytes; Cumulus cells; Cathepsin B; Apoptosis; E-64;
Research articleBiochemical characterization of the triticale TsPAP1, a new type of plant prolyl aminopeptidase, and its impact on proline content and flowering time in transgenic Arabidopsis plants
Keywords: Flowering; Proline; Prolyl aminopeptidase; Serine peptidase; Substrate specificity; Triticosecale; DFP; diisopropyl fluorophosphate; E-64; (trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane); β-NA; β-naphthylamide; PAP; prolyl aminopeptidase; PMSF;
Growth arrest and morphological changes triggered by emodin on Trypanosoma cruzi epimastigotes cultivated in axenic medium
Keywords: Trypanosoma cruzi epimastigotes; Emodin; Cytoskeleton; Protein kinase CK2; Tubulin; Cytokinesis; Chagas disease; 2,3-BPG; 2,3-bisphosphoglycerate; DRB; 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole; KN-62; 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-l-ty
Characterization of functional proteases from flowers of tea (Camellia sinensis) plants
Keywords: Amino acid; Camellia sinensis; Flower; Protease; Serine carboxypeptidase-like protein; Tea; L-Asparagine (PubChem CID: 6267); L-Aspartic acid (PubChem CID: 5960); L-Glutamate (PubChem CID: 33032); L-Isoleucine (PubChem CID: 6306); L-Leucine (PubChem CID:
Differential expression of cathepsins K, S and V between young and aged Caucasian women skin epidermis
Keywords: AMC; 7 amino-4 methylcoumarin; DEJ; dermal-epidermal junction; DTT; dithiothreitol; ECM; extracellular matrix; E-64; L-3-carboxy-trans-2, 3-epoxypropionyl-leucylamido-(4-guanidino) butane; MMP; matrix metalloprotease; Z; Benzyloxycarbonyl; Aging; Cystei
Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus
Keywords: AMC; 7-amido-4-methylcoumarin; AMg; anterior midgut; DAPI; 4â²,6-DiAmidino-2-PhenylIndole; E-64; l-trans-epoxysuccinyl-leucylamido (4-guanidino) butane; FP; faecal pellet; FRET; Förster Resonance Energy Transfer; HDM(e); house dust mite (extracts); Hg;
Molecular and functional characterization of metalloserrulases, new metalloproteases from the Tityus serrulatus venom gland
Keywords: Tityus serrulatus; Metalloprotease; Metalloserrulase; Venom; Scorpion; Envenomation; MCA; 7-methoxycoumarin-4-acetic acid; TsMS; metalloserrulase; Ts; Tityus serrulatus; EDTA; ethylenediaminetetraacetic acid; DPA; Nb-(2,4-dinitrophenyl)-L-2,3-diaminopropi
Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation
Keywords: AD; Alzheimer disease; Aβ; β-amyloid; APP; amyloid precursor protein; ASMase; acid sphingomyelinase; BACE; β-secretase β-site amyloid cleaving enzyme; BBB; blood-brain barrier; BCA; bicinchoninic acid; BHT; butylated hydroxytoluene; BSO; buthionine
Deletion of the calmodulin-binding domain of Grb7 impairs cell attachment to the extracellular matrix and migration
Keywords: AEBSF; 4-(2-aminoethyl)-benzenesulfonyl fluoride; CaM; calmodulin; CaM-BD; calmodulin-binding domain; BPS; between PH and SH2; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbeccoâ²s modified Eagleâ²s medium; E-64; N-[N- (L-3-trans-carboxyirane-2-carbo
Carbohydrate digestion in ticks and a digestive α-l-fucosidase
Keywords: MUFUC; 4-methylumbelliferyl α-l-fucopyranoside; E-64; 1-[L-N-(trans-epoxysuccinyl)leucyl]amino-4-guanidinobutane; TLC; thin layer chromatography; Chitinase; Glycoside hydrolases; α-l-fucosidase; Ticks; Digestion; Fucoidan;
Specific cleavage of the lung surfactant protein A by human cathepsin S may impair its antibacterial properties
Keywords: Abz; ortho-aminobenzoic acid; AEBSF; 4-(2-aminoethyl) benzenesulfonyl fluoride hydrochloride; AMC; 7-amino-4-methyl coumarin; BALF; broncho-alveolar lavage fluid; BCA; bicinchoninic acid; CA-074; N-(l-3-trans-propylcarbamoyloxirane-2-carbonyl)-l-isoleucyl
Conformational mobility of active and E-64-inhibited actinidin
Keywords: Actinidin; E-64; Molecular dynamics; Cysteine protease;
Antiparasitic effect of a fraction enriched in tight-binding protease inhibitors isolated from the Caribbean coral Plexaura homomalla
Keywords: AAFP; N-(4-metoxiphenylazoformyl)-L-phenylalanine; ACN; acetonitrile; AMC; 7-amino-4-methyl coumarin; AU; absorbance units; BAPA; benzoyl-arginyl-p-nitro-anilide-HCl; CMD; carboxymethyl dextran; E-64; trans-epoxysuccinyl-l-leucylamido-(4-guanidino)butane;
Characterization of two novel subtilases from common bean (Phaseolus vulgaris L.) and their responses to drought
Keywords: Common bean; Drought; Expression; Phaseolus vulgaris; Protease; Regulation; Subtilase; AHSP; Arachis hypogaea serine protease; AMC; 7-amino-4-methylcoumarin; Bz; N-benzoyl; C; control plants; D I; plants three days after last watering; D II; plants six da
Expression of recombinant human cathepsin K is enhanced by codon optimization
Keywords: CTSK; cathepsin K; proCTSK; procathepsin K; rproCTSK; recombinant proCTSK; IPTG; isopropyl-β-d-thiogalactopyranoside; PMSF; phenylmethanesulfonylfluoride; IB; inclusion body; GSH; reduced glutathione; GSSG; oxidized glutathione; E-64; 1-[l-N-(trans-epoxy
DEVDase activity is induced in potato leaves during Phytophthora infestans infection
Keywords: DEVDase; Plant caspases; Potato; P. infestans; Apoplastic proteins; Ac-DEVD-AFC; N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin; Ac-DEVD-CHO; N-acetyl-Asp-Glu-Val-Asp-CHO (aldehyde); DTT; dithiothreitol; E-64; trans-epoxysuccinyl-l-leucylamid
Purification, kinetic characterization and properties of a novel thermo-tolerant extracellular protease from Kluyveromyces marxianus IFO 0288 with potential biotechnological interest
Keywords: DMF; dimethyl formamide; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; E-64; 1-[[N-(l-3-trans-carboxyoxiran-2-carbonyl)-l-leucyl]amino]-4-guanidinobutane; EDTAK2; ethylene-diaminetetraacetate bi-potassium salt; K. marxianus; Kluyveromyces marxianus (Hans
Substrate specificity of Staphylococcus aureus cysteine proteases - Staphopains A, B and C
Keywords: Protease; Staphopain; Staphylococcal virulence; Substrates library; Substrate specificity; Ac; acetyl; ABZ; amino benzoic acid; ANB-NH2; amide of 5-amino-2-nitrobenzoic acid; ACC; 7-amino-4-carbamoylmethylcoumarin; CL; competition labeling; CLiPS; cellula
Carboxypeptidase I from triticale grains and the hydrolysis of salt-soluble fractions of storage proteins
Keywords: Carboxypeptidase I; Endopeptidase; Expression of carboxypeptidase I gene; Germination; Storage protein hydrolysis; Triticale; CABS-Sepharose 4B; [N-(É-aminocaproyl)-p-aminobenzyl]succinyl-Sepharose 4B; CP; carboxypeptidase; DFP; diisopropylfluorophosphat
Activation of the BRCA1/Chk1/p53/p21Cip1/Waf1 pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells
Keywords: AEBSF; 4-(2-aminoethyl)-benzenesulfonyl fluoride; ATM; ataxia telangiectasia mutated; ATR; AT- and Rad3-related; BRCA1; breast cancer susceptibility protein-1; CDKI; cyclin-dependent kinase inhibitor; DAF-DA; 4,5-diaminofluorescein diacetate; Cdk; cyclin-
The effect of adipokinetic hormone on midgut characteristics in Pyrrhocoris apterus L. (Heteroptera)
Keywords: AEBSF; 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride; AKH; adipokinetic hormone; AM; anterior midgut; DGs; diacylglycerols; DNS; 3,5-dinitrosalicylic acid reagent; DTT; dithiotreitol; E-64; l-trans-epoxysuccinyl-l-leucylamido(4-guanidino) butane;
The peptidases of Trypanosoma cruzi: Digestive enzymes, virulence factors, and mediators of autophagy and programmed cell death
Keywords: CPs; cysteine proteinases; SPs; serine proteinases; MPs; metalloproteinases; APs; aspartyl proteinases; 20S and 26S proteasome: proteasome oligomers with a sedimentation coefficient of 20S and 26S; respectively; Z; N-benzyloxycarbonyl; NHMec; amidomethyl
Molecular cloning and characterization of procirsin, an active aspartic protease precursor from Cirsium vulgare (Asteraceae)
Keywords: AP; aspartic proteinase; DABCYL; [4-((4-(dimethylamino)phenyl)azo)benzoic acid]; E-64; trans-epoxysucciny-L-leucyl-amido (4-guanidino) butane; EDANS; 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid; EDTA; ethylenediaminetetraacetic acid; EPNP; 1,2-epox
Digestive physiology and characterization of digestive cathepsin L-like proteinase from the sugarcane weevil Sphenophorus levis
Keywords: DTT; dithiotreitol; SBTI; soybean trypsin inhibitor; Z-FR48 MCA; benzyloxycarbonyl-Phe-Arg-7-amino-4-methylcoumarin; Z-RR-MCA; benzyloxycarbonyl-Arg-Arg-7-amino-4-methylcoumarin; Z-LR-MCA; benzyloxycarbonyl-Leu-Arg-7-amino-4 methylcoumarin; E-64; l-trans-
Ginger rhizome as a potential source of milk coagulating cysteine protease
Keywords: Zingiber officinale; Zingiberaceae; Purification; Characterization; Plant rennet; Cysteine protease; N-terminal sequence; GP-I; ginger protease I; GP-II; ginger protease II; GP-2; ginger protease 2; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel
Adult and juvenile Fasciola cathepsin L proteases: Different enzymes for different roles
Keywords: Cathepsin L; Fasciola spp.; S2 subsite; Substrate specificity; AMC; 7-amino-4-methylcoumarin; ES; excretory/secretory material; EDTA; ethylene-diamine-tetraacetic acid (tetrasodium salt); E-64; trans-epoxysuccinyl-l-leucylamido(4-guanidino)-butane; NEJ; n
Biochemical characterisation of MX-4, a plant cysteine protease of broad specificity and high stability
Keywords: E-64; trans-epoxysuccinyl-l-leucylamido(4-guanidino)-butane; SDS; sodium dodecyl sulphate; BAPNA; Nα-benzoyl-dl-arginine-p-nitroanylide; EDTA; ethylenediaminetetraacetic acid; BCA; protein assay reagent commercial kit. MX-4, mexicain; GP-I and GP-II; two
Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes
Keywords: Keratinocytes; house dust mite; caspase-1; IL-1β; IL-18; NLRP3; inflammasome; Dermatophagoides pteronyssinus; Der p 1; AD; Atopic dermatitis; ASC; Apoptosis-associated specklike protein containing a caspase-recruitment domain; E-64; Trans-epoxysuccinyl L
Mitochondrial intermediate peptidase: Expression in Escherichia coli and improvement of its enzymatic activity detection with FRET substrates
Keywords: PMSF; phenylmethanesulfonylfluoride; E-64; (2S,3S)-3-(N-{(S)-1-[N-(4-guanidinobutyl)carbamoyl]3-methylbutyl}carbamoyl)oxirane-2-carboxylic acid; JA-2; N-[1-(R,S)-carboxy-3-phenylpropyl]Ala-Aib-Tyr-p-aminobenzoate; FRET; fluorescence resonance energy trans
Downstream effects of haemoglobinase inhibition in Plasmodium falciparum-infected erythrocytes
Keywords: DMSO; dimethylsulphoxide; E-64; l-trans-epoxy-succinyl-leucylamido-(4-guanidino)-butane; IC50; 50% inhibitory concentration; iRBC; infected red blood cell (erythrocyte); MACS; magnet-activated cell sorting; PBS; phosphate-buffered saline; p.i.; post-invas
Comparative study of mature and zymogen mite cysteine protease stability and pH unfolding
Keywords: AMC; 7-amino-4-methylcoumarin; ANS; 8-anilino-1-naphthalenesulfonic acid; BMGY; Yeast Glycerol Buffered Media; Boc; N-t-butoxy-carbonyl; C34A; replacement of the catalytic cysteine (C34) by an alanine; DTT; dithiotreitol; E-64; L-trans-epoxysuccinyl-leucy
Dubiumin, a chymotrypsin-like serine protease from the seeds of Solanum dubium Fresen
Keywords: Solanum dubium Fresen; Solanaceae; Purification; Characterization; Serine protease; Dubiumin; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; PMSF; phenylmethanesulfonyl fluoride; GuHCl; guanidine hydrochloride; EDTA; ethylenediam
Indicain, a dimeric serine protease from Morus indica cv. K2
Keywords: BAPA; NR-benzoylarginine p-nitroanilide; BLAST; basic local alignment search tool; BSA; bovine serum albumin; DFP; diisopropylfluorophosphate; DMSO; dimethyl sulfoxide; DTNB; 5,5μ-dithiobis(2-nitrobenzoic acid); E-64; 3S)-3-(N-{(S)-1-[N-(4-guanidinobutyl
Cellular repressor of E1A-stimulated genes is a bona fide lysosomal protein which undergoes proteolytic maturation during its biosynthesis
Keywords: CA-074; N-(l-3-trans-propylcarbamoyloxirane-2-carbonyl)-l-isoleucyl-l-proline; CREG; Cellular repressor of E1A-stimulated genes; E-64; N-(l-3-trans-carboxyoxirane-2-carbonyl)-l-leucyl-(4-guanidino)-butane; endo H; endo-β-N-acetyl-glucosaminidase H; ER; e
Cystatin C stimulates the differentiation of mouse osteoblastic cells and bone formation
Keywords: Cystatin C; Osteoblast differentiation; Mineralization; Bone formation; BMP-2; Runx2; Osteocalcin; E-64; Ex vivo calvarial culture
Hydrolysis of surimi paste from walleye pollock (Theragra chalcogramma) by cysteine proteinase cathepsin L and effect of the proteinase inhibitor (E-64) on gelation
Keywords: Cathepsin L; Cysteine protease; Walleye pollock surimi; Hydrolysis; E-64; Gel strength
Cysteine proteinase 30 in clinical isolates of T. vaginalis from symptomatic and asymptomatic infected women
Keywords: Trichomonas vaginalis; Cytoadherence; Trichomoniasis; CP30; cysteine proteinase 30; c.p.m.; count per minute; E-64; l-trans-epoxysuccinyl-leucylamide-(4-guanido)-butane; HIS; hyperimmune serum; NRS; normal rabbit serum; VECs; vaginal epithelial cells;
Entamoeba histolytica: ADP-ribosylation of secreted glyceraldehyde-3-phosphate dehydrogenase
Keywords: Ameba; Cysteine synthase A; Extracellular GAPDH; Glyceraldehyde-3-phosphate dehydrogenase phosphorylating (EC 1.2.1.12); Human parasite; Mono-ADP-ribosylation; Protozoa; NAD+; DTT; dithiothreitol; E-64; trans-Epoxysuccinyl-l-leucylamido(4-guanidino)-butan
Plasmodium falciparum: Biochemical characterization of the cysteine protease falcipain-2â²
Keywords: Plasmodium falciparum; Malaria; Cysteine protease; Proteinase; Hemoglobin; Falcipain; DTT; dithiothreitol; GSH; reduced glutathione; AMC; 7-amino-4-methyl coumarin; E-64; trans-epoxysuccinyl-l-leucylamido-(4-guanidino)butane; Mu-Leu-Hph-VSPh; morpholine u
Pathogenesis of Acute Experimental Liver Amebiasis
Keywords: Experimental liver abscess; Hamster; Cysteine proteases; E-64; Inflammation; Complement; Ischemia
Differentiation of Leishmania major is impaired by over-expression of pyroglutamyl peptidase I
Keywords: kb; kilobase(s); bp; base pairs; PPI; gene encoding pyroglutamyl peptidase I; PPI; protein encoded by PPI; rLmPPI; recombinant L. major PPI; PCR; polymerase chain reaction; RT PCR; reverse transcriptase PCR; PAGE; polyacrylamide gel electrophoresis; MTT;
Plasmodium falciparum serine-repeat antigen (SERA) forms a homodimer through disulfide bond
Keywords: SERA; serine-repeat antigen; IP; immunoprecipitation; DFP; diisopropylfluorophosphate; E-64; trans-epoxysuccinyl-l-leucyl-amido(4-guanidino)butane; Plasmodium falciparum; Serine-repeat antigen; Dimer formation; Protein processing;
A novel protease from Entamoeba histolytica homologous to members of the family S28 of serine proteases
Keywords: DPP; dipeptidyl peptidase; PRCP; prolylcarboxypeptidase; Suc-AAF-AMC; N-succinyl-l-Ala-l-Ala-l-Phe-7-amido-4-methylcoumarin; DFP; di-isopropyl fluorophosphate; E-64; 1-trans-epoxysuccinyl-l-leucilamide-(4-guanidine)-butane; EDTA; ethylenediaminetetraaceti