Activation of PKA and Epac proteins by cyclic AMP depletes intracellular calcium stores and reduces calcium availability for vasoconstriction
Keywords: AVP, arginine-vasopressin; [Ca2 +]c, cytoplasmic Ca2 + concentration; cAMP, 3′,5′-cyclic adenosine monophosphate; db-cAMP, dibutyryl cyclic AMP; DMSO, dimethyl sulfoxide; Epac, exchange protein directly activated by cAMP; FBS, foetal bovine serum; KBS, Kr