Keywords: BB; bevacizumab-bevacizumab; BP; bevacizumab followed by panitumumab; CA9; carbonic anhydrase 9; CRC; colorectal cancer; DEGs; differentially expressed genes; EGFR; epidermal growth factor receptor; EPHA2; ephrin type-A receptor 2; FASN; fatty acid syntha
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Keywords: BBB; blood brain barrier; CAR; chimeric antigen receptor; CNS; central nervous system; CRS; cytokine release syndrome; EGFR; epidermal growth factor receptor; EGFRvIII; variant 3 of epidermal growth factor receptor; epha2; erythropoietin producing hepatoc
Keywords: CPPs; cell-penetrating peptides; CS; chitosan; DBP; DNA binding peptide; DMMAn; dimethylmaleic anhydride; EAP; eight-armed polyethylene glycol; EAPP; EAP-PEI copolymer; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; Eph; hepatocellu
Keywords: Targeted receptor TKIs; Acquired resistance to receptor TKIs; Overcoming drug resistance; Driver oncogenes; Gate keeper receptor mutations; Bypass signaling molecules; ABC; ATP-binding cassette; AKT/PKB; Protein kinase B; ALK; Anaplastic lymphoma kinase;
Keywords: A-bomb; atomic bomb; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; ATPase; adenosine triphosphatase; BER; base excision repair; Ca2+; calcium ions; CDKN1A; cyclin-dependent kinase inhibitor 1A; CHO; Chinese hamster ovary; COX-2; cycloox
Keywords: Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A
Keywords: 17-AAG; 17-(Allylamino)-17-demethoxygeldanamycin; 17-DMAG; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin; AKT; v-akt murine thymoma viral oncogene homolog; APC; antigen presenting cell; ATM; Ataxia telangiectasia mutated; ATR; Ataxia telangiectasia
MicroRNA-124-3p represses cell growth and cell motility by targeting EphA2 in glioma
Keywords: MicroRNA-124-3p; EphA2; Glioma; Motility;
Tyrosine kinase activity of EphA2 promotes its S897 phosphorylation and glioblastoma cell proliferation
Keywords: EphA2; ERK; Cell proliferation; Glioblastoma; BrdU; bromodeoxyuridine; EGF; epidermal growth factor; ICD; intracellular domain; PI3K; phosphatidylinositol 3-kinase; PKA; protein kinase A; RSK; p90 ribosomal S6 kinase; RTK; receptor tyrosine kinase; S897;
Epha2 and Efna5 participate in lens cell pattern-formation
Keywords: EPH; erythropoietin producing hepatocellular-carcinoma; EPHA2; EPH receptor A2 or ephrin type-A receptor 2 protein symbol; EFNA5; ephrin-A5 protein symbol; Epha2; mouse EPHA2 gene symbol; Efna5; mouse ephrin-A5 gene symbol; EdU; 5-ethynyl-2'deoxyuridine;
Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2
Keywords: Sam domains; Stapled peptides; PPI inhibitors; EphA2; Cancer;
Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer
Keywords: HDACs; EphA2; WW437; Breast cancer; Growth; Metastasis;
Design and synthesis of small molecule agonists of EphA2 receptor
Keywords: EphA2; Doxazosin; Small molecular ligand; Dimer; Internalization;
Antibody-drug conjugates (ADCs): Potent biopharmaceuticals to target solid and hematological cancers- an overview
Keywords: Antibody-drug conjugates; Monoclonal antibodies; Anticancer; Drug resistance; Solid tumors; Hematological tumors; ADC; Antibody-Drug Conjugate; ALCL; Anaplastic Large Cell Lymphoma; ALL; Acute Lymphoblastic Leukemia; AML; Acute Myeloid Leukemia; BCMA; B C
Structural investigation of a C-terminal EphA2 receptor mutant: Does mutation affect the structure and interaction properties of the Sam domain?
Keywords: EphA2; Sam domain; NMR; Molecular dynamics;
Permissiveness of human hepatocellular carcinoma cell lines for hepatitis C virus entry and replication
Keywords: HCV; hepatitis C virus; pegIFN-α; pegylated interferon alpha; DAAs; direct acting antivirals; BCLC; Barcelona ClÃnic Liver Cancer; IF; immunofluorescence; HCVpp; HCV pseudoparticles; HCVcc; HCV cell culture; JFH1; Japanese fulminant hepatitis 1; Apo; ap
The role of WT1 isoforms in vasculogenic mimicry and metastatic potential of human triple negative breast cancer cells
Keywords: WT1 isoforms; Triple negative breast cancer; Vasculogenic mimicry; Cell migration; EphA2; β-catenin;
All-trans retinoic acid attenuates bleomycin-induced pulmonary fibrosis via downregulating EphA2-EphrinA1 signaling
Keywords: Bleomycin; Pulmonary fibrosis; All-trans retinoic acid; EphA2; EphrinA1;
The SAM domain inhibits EphA2 interactions in the plasma membrane
Keywords: Receptor tyrosine kinase; EphA2; SAM domain; Interactions;
Chronic TCDD exposure results in the dysregulation of gene expression in splenic B-lymphocytes and in the impairments in T-cell and B-cell differentiation in mouse model
Keywords: Chronic; TCDD; B cell; transcriptome; EphA2; cAMP
EphA2 is a key effector of the MEK/ERK/RSK pathway regulating glioblastoma cell proliferation
Keywords: EphA2; RSK; EGF; Cell proliferation; Glioblastoma;
EphA2 is a biomarker of hMSCs derived from human placenta and umbilical cord
Keywords: biomarker; EphA2; fibroblast; immunomodulation; mesenchymal stem cells
EphA2 modulates radiosensitive of hepatocellular carcinoma cells via p38/mitogen-activated protein kinase-mediated signal pathways
Keywords: EphA2; Hepatocellular carcinoma cells; p38/mitogen-activated protein kinase; Radiosensitivity
Cell-penetrating peptide-siRNA conjugate loaded YSA-modified nanobubbles for ultrasound triggered siRNA delivery
Keywords: Ultrasound; Nanobubbles; EphA2; Cell-penetrating peptides; siRNA delivery;
Preclinical and clinical development of siRNA-based therapeutics
Keywords: 2â²-OMe; 2â²-O-methyl; 2â²-F; 2â²-fluoro; CH/TA; chitosan/thioaptamer; DOPC; 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine; DOTAP; 1,2-dioleoyl-3-trimethylammonium-propane; DOTMA; N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl sulfate; E
EphB6 promotes anoikis by modulating EphA2 signaling
Keywords: EphA2; EphB6; Ephexin4; Anoikis; Heterotypic interaction;
The role of miR-200a in vasculogenic mimicry and its clinical significance in ovarian cancer
Keywords: miR-200a; Vasculogenic mimicry; EphA2; Ovarian cancer;
Ephexin4-mediated promotion of cell migration and anoikis resistance is regulated by serine 897 phosphorylation of EphA2
Keywords: RhoG; Cell migration; Anoikis resistance; EphA2; Ephexin; RhoGEFGEF, guanine nucleotide exchange factor; GAP, GTPase-activating protein; SAM, sterile-α-motif; poly-HEMA, poly-hydroxyethylmethacrylate.
Prognostic Significance of Combinations of RNA-Dependent Protein Kinase and EphA2 Biomarkers for NSCLC
Keywords: PKR; EphA2; Biomarker; Lung cancer
Higher expression of EphA2 and ephrin-A1 is related to favorable clinicopathological features in pathological stage I non-small cell lung carcinoma
Keywords: EphA2; Ephrin-A1; mRNA; Immunohistochemical staining; Pathological stage I; Non-small cell lung cancer (NSCLC); Surgery; Prognosis;
Eph/ephrin signaling in epidermal differentiation and disease
Keywords: Cell–cell communication; Cell adhesion; Desmosome; EphA2; Epithelial; Cadherin
A novel vaccine containing EphA2 epitope and LIGHT plasmid induces robust cellular immunity against glioma U251 cells
Keywords: Vaccine; EphA2; LIGHT; Glioma; Immunotherapy
Molecular targeting of malignant glioma cells with an EphA2-specific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells
Keywords: Immunotoxin; EphA2; Mesenchymal stem cells; Malignant glioma; Gene therapy
Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase
Keywords: Ephexin4; RhoG; Anoikis; PI3-kinase; Akt; EphA2
Pathway-based genome-wide association analysis identified the importance of EphrinA-EphR pathway for femoral neck bone geometry
Keywords: PAK1; p21-activated kinase 1; FAK1; PTK2 protein tyrosine kinase 2; EphA7; Eph receptor A7; PIK3CG; phosphoinositide-3-kinase, catalytic, gamma; PAK7; p21-activated kinase 7; RASA1; RAS p21 protein activator 1; FYN; FYN oncogene related to SRC, FGR, YES;
High yield expression of non-phosphorylated protein tyrosine kinases in insect cells
Keywords: Kinase; Phosphatase; Phosphorylation; Baculovirus; Insect cells; Coexpression; BTK; JAK3; EphA2; YopH;
Expression of EphA2 and VEGF in squamous cell carcinoma of the tongue: Correlation with the angiogenesis and clinical outcome
Keywords: EphA2; VEGF; Tongue neoplasms; Neovascularization; Squamous cell carcinoma; Immunohistochemistry
Receptor EphA2 activation with ephrinA1 suppresses growth of malignant mesothelioma (MM)
Keywords: EphA2; EphrinA1; Malignant mesothelioma; Receptor tyrosine kinase; Proliferation; ERK1/2
Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells
Keywords: Epigallocatechin gallate; Ephrin-A1; EphA2; PI-3K; ERK-1/2; Cell migration; Angiogenesis
Anti-EphA2 Antibodies Decrease EphA2 Protein Levels in Murine CT26 Colorectal and Human MDA-231 Breast Tumors But Do Not Inhibit Tumor Growth
Keywords: EphA2; ephrinAl; antibodies; colorectal cancer; breast cancer;
EphA2 as a Glioma-Associated Antigen: A Novel Target for Glioma Vaccines
Keywords: EphA2; glioma; cancer vaccine; cytotoxic T lymphocytes; human leukocyte antigen (HLA) A2; CTL; cytotoxic T lymphocyte; DC; dendritic cell; E/T ratio; effector-to-target ratio; HLA; human leukocyte antigen; IL; interleukin; PBMC; peripheral blood mononucle
The clinical significance of EphA2 and Ephrin A-1 in epithelial ovarian carcinomas
Keywords: EphA2; Ephrin A-1; Epithelial ovarian carcinoma; OVCAR3; SKOV3; Immunohistochemistry; RT-PCR; Laser capture microdissection; Western blot;