Keywords: FAP, fibroblast activation protein; POP, prolyl oligopeptidase; TME, tumor microenvironment; DPPIV, dipeptidyl peptidase IV; ECM, extracellular matrix; IHC, immunohistochemistry; CAFs, cancer-associated fibroblasts; MMPs, matrix metalloproteinases
مقالات ISI (ترجمه نشده)
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Keywords: BSA, bovine serum albumin; ECM, extracellular matrix; ELISA, enzyme-linked immunosorbent assay; ERα, estrogen receptor α; ERβ, estrogen receptor β; FAP, fibroblast activation protein; HBSS, Hanks balanced salt solution; IGF, insulin-like growth factor; MI
Digitoxin enhances the growth inhibitory effects of thapsigargin and simvastatin on ER negative human breast cancer cells
Keywords: DAG, diacylglycerol; D7, diospyrin diethylether; ER, endoplasmic reticulum; FAP, fibroblast activation protein; HCC, hepatocellular cancer; HMGR, HMG-CoA reductase; IAP, inhibitor of apoptosis; IP3, inositol 1,4,5-trisphosphate; 4NQO, 4-Nitroquinoline 1-o
MicroRNA-106b in cancer-associated fibroblasts from gastric cancer promotes cell migration and invasion by targeting PTEN
Keywords: CAFs, cancer associated fibroblasts; NFs, normal fibroblasts; miRNA, microRNA; PTEN, protein tyrosine phosphatase and tensin homologue; α-SMA, α-smooth muscle actin; FSP1, fibroblast specific protein 1; FAP, fibroblast activation protein; TGF-β, transform
Design, synthesis and biological evaluation of 4-fluoropyrrolidine-2-carbonitrile and octahydrocyclopenta[b]pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors
Keywords: DPP4 inhibitors; GLP-1; Selectivity; Oral bioavailability; Oral glucose tolerance tests; hERGDPP4, dipeptidyl peptidase IV; GLP-1, glucagon-like peptide-1; FAP, fibroblast activation protein; T2DM, type 2 diabetes mellitus; SARs, structure–activity relati
Lost in disruption: Role of proteases in glioma invasion and progression
Keywords: ADAM, a disintegrin and metalloproteinase; ADAMTS, ADAMs with thrombospondin motifs; bFGF, basic fibroblast growth factor; ECM, extracellular matrix; EGF, epidermal growth factor; FAP, fibroblast activation protein; GAG, glycosaminoglycan; GFAP, glial fib
Dipeptidyl peptidase-IV inhibits glioma cell growth independent of its enzymatic activity
Keywords: DPP, dipeptidyl peptidase; FAP, fibroblast activation protein; SDF-1, stromal cell derived factor; SP, substance P; DMEM, Dulbecco's Modified Eagle's Medium; FBS, fetal bovine serum; GFAP, glial fibrillary acidic protein; BSA, bovine serum albumin; MACS,
Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor
Keywords: DPP, dipeptidyl peptidase; DPP-IV, dipeptidyl peptidase IV; FAP, fibroblast activation protein; FDA, the US Food and Drug Administration; IV, intravenous; SD, Sprague–Dawley; GLP, Good Laboratory Practice; CC50, cytotoxic concentration; AUC, the area unde
Targeted lipid-coated nanoparticles: Delivery of tumor necrosis factor-functionalized particles to tumor cells
Keywords: AEMH, 2-aminoethyl-methacrylate hydrochloride; Chol, cholesterol; EPC, egg phosphatidylcholine; FAP, fibroblast activation protein; L, liposome; LP, lipid-coated particle; Mal-PEG2000-DSPE, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(poly
Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly2-Pro1-cleaving specificity
Keywords: FAP, fibroblast activation protein; DPP-4, dipeptidyl peptidase-4; POP, prolyl oligopeptidase; α2AP, α2-antiplasmin; cmk, chloromethyl ketone; AFC, 7-amino-4-trifluoromethyl coumarin; Ac, acetyl; EDANS, 5-[(2-Aminoethyl)amino]naphthalene-1-sulfonic acid;
Molecular characterization of a novel dipeptidyl peptidase like 2-short form (DPL2-s) that is highly expressed in the brain and lacks dipeptidyl peptidase activity
Keywords: BLAST, Basic Local Alignment Search Tool; DP, dipeptidyl peptidase; DPL, DP-like; FAP, fibroblast activation protein; ISA, A-type Kv current; Kv channel, voltage-gated potassium channel; KChIP, Kv channel interacting protein; GFP, green fluorescent protei