Keywords: GAGs، glycosaminoglycans; CAT, catalase; DCF-DA, 2′,7′-dichlorofluorescein diacetate; DS, dermatan sulfate; eNOS, endothelial nitric oxide synthase; FBS, fetal bovine serum; FMH, fast-moving heparin fraction; GAGs, glycosaminoglycans; GAPDH, glyceraldehyde 3-phosphate dehydrogenas
مقالات ISI GAGs، glycosaminoglycans (ترجمه نشده)
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Keywords: GAGs، glycosaminoglycans; ERT, Enzyme replacement therapy; FEV0.5, forced expiratory volume in 0.5 s; FVC, forced vital capacity; GAGs, glycosaminoglycans; HSCT, hematopoietic stem cell transplantation; IV, intravenous; MMEF, maximum midexpiratory flow; MPS-I, mucopolysaccharidosi
Keywords: GAGs، glycosaminoglycans; 6MWT, Six minute walking test; BAER, Brainstem auditory evoked responses; CNS, Central nervous system; EF, Ejection fraction; ERT, Enzyme replacement therapy; ENT, Ear nose and throat; GAGs, Glycosaminoglycans; HAQ, Health Assessment Questionnaire; I2S, I
Keywords: GAGs، glycosaminoglycans; BMD, bone mineral density; DXA, dual energy X-ray absorptiometry; GAGs, glycosaminoglycans; GLB1, betagalactosidease; HAZ, height-adjusted Z-score; HGMD, The Human Gene Mutation Database; KS, keratan sulfate; LDF, lateral distal femur; LS, lumbar spine; M
Photochemical depolymerisation of dermatan sulfate and analysis of the generated oligosaccharides
Keywords: GAGs، glycosaminoglycans; GAGs, glycosaminoglycans; LMWH, low molecular weight heparin; DS, dermatan sulfate; GalNAc, N-acetylgalactosamine; IdoA, iduronic Acid; HSQC, heteronuclear single quantum coherence; TOCSY, total correlation spectroscopy; HMBC, heteronuclear multiple bond
TrxR2 deficiencies promote chondrogenic differentiation and induce apoptosis of chondrocytes through mitochondrial reactive oxygen species
Keywords: GAGs، glycosaminoglycans; TrxR2, thioredoxin reductase 2; Se, selenium; ROS, reactive oxygen species; GAGs, glycosaminoglycans; Sox9, SRY (sex determining region Y)-box 9; Col X, type X collagen alpha1; Col II, collagen type II; Acan, aggrecan; ECM, extracellular matrix; PTHrP, pa
A new paradigm for XOR-catalyzed reactive species generation in the endothelium
Keywords: GAGs، glycosaminoglycans; GAGs, glycosaminoglycans; GTN, glycerol trinitrate; H2O2, hydrogen peroxide; NO, nitric oxide; NOS, nitric oxide synthase; O2−, superoxide; ROS, reactive oxygen species; SOD, superoxide dismutase; XDH, xanthine dehydrogenase; XO, xanthine oxidase; XOR, xa
Following the enzymatic digestion of chondroitin sulfate by a simple GPC analysis
Keywords: GAGs، glycosaminoglycans; GAGs, glycosaminoglycans; ECM, extracellular matrix; CS, chondroitin sulfates; GalNAc, N-acetylgalactosamine; GlcA, glucuronic acid; HPLC, high-performance liquid chromatography; GPC, gel permeation chromatography; SEC, size-exclusion chromatography; NMR,
The effect of the decoy molecule PA401 on CXCL8 levels in bronchoalveolar lavage fluid of patients with cystic fibrosis
Keywords: GAGs، glycosaminoglycans; CF, cystic fibrosis; BALF, bronchoalveolar lavage fluid; GAGs, glycosaminoglycans; FEV1, forced expiratory volume in 1 sCystic fibrosis; Bronchoalveolar lavage fluid; Glycosaminoglycan; Interleukin-8/CXCL8; Antagonist decoy; Neutrophils
Characterization of the MPS I-H knock-in mouse reveals increased femoral biomechanical integrity with compromised material strength and altered bone geometry
Keywords: GAGs، glycosaminoglycans; MPS I, mucopolysaccharidosis type I; IDUA, α-L-iduronidase; GAGs, glycosaminoglycans; μCT, microcomputed tomography; BMDD, bone mineral density distribution; FWHM, full width at half maximum; BV/TV, bone volume/total volume; SMI, structure model index; Tm
In vitro assessment of biopolymer-modified porous silicon microparticles for wound healing applications
Keywords: GAGs، glycosaminoglycans; ATR-FTIR, attenuated total reflectance Fourier transform infrared; CHI, chitosan; CS, chondroitin sulfate; DMEM, Dulbecco’s modified Eagle’s medium; ECM, extracellular matrix; FTIR, Fourier transform infrared; GAGs, glycosaminoglycans; HA, hyaluronic acid
Xanthine oxidoreductase-catalyzed reactive species generation: A process in critical need of reevaluation
Keywords: GAGs، glycosaminoglycans; GAGs, glycosaminoglycans; H2O2, hydrogen peroxide; I/R, ischemia/reperfusion; •NO, nitric oxide; NOS, nitric oxide synthase; O2•−, superoxide; ROS, reactive oxygen species; XDH, xanthine dehydrogenase; XO, xanthine oxidase; XOR, xanthine oxidoreductase)Fr
Enhancement of thermal stability of chondroitinase ABC I by site-directed mutagenesis: An insight from Ramachandran plot
Keywords: GAGs، glycosaminoglycans; cABC I, Chondroitinase ABC I; C6S, Chondroitin-6-sulfate; C4S, Chondroitin-4-sulfate; DS, Dermatan sulfate; GAGs, Glycosaminoglycans; CSPG, Chondroitin sulfate proteoglycan; SCI, Spinal cord injury; CD, Circular dichroism; PDB, Protein Data BankChondroiti
Characterization of α-l-Iduronidase (Aldurazyme®) and its complexes
Keywords: GAGs، glycosaminoglycans; IDUA, Alpha-l-Iduronidase; GAGs, glycosaminoglycans; 2-DE, Two-dimensional gel electrophoresis; DDM, n-dodecyl β-d-maltosidaseα-l-Iduronidase; Mass spectrometry; Mucopolysaccharide; Mucopolysaccharidosis type I; Post-translational modification; Glycosylat
Stress-relaxation response of human menisci under confined compression conditions
Keywords: GAGs، glycosaminoglycans; BW, Body weight; OA, Osteoarthritis; GAGs, Glycosaminoglycans; DNA, Deoxyribonucleic acid; HA, Aggregate modulus; k, Hydraulic permeability; Eeq, Equilibrium modulus; 1-D, One-dimension(al); AH, Anterior (meniscal) horn; PI, Pars intermedia; PH, Posterior
Heparan sulfate and dermatan sulfate derived disaccharides are sensitive markers for newborn screening for mucopolysaccharidoses types I, II and III
Keywords: GAGs، glycosaminoglycans; MPSs, mucopolysaccharidoses; LSDs, lysosomal storage disorders; GAGs, glycosaminoglycans; HSCT, hematopoietic stem cell transplantation; ERT, enzyme replacement therapy; MPS IIIA, mucopolysaccharidosis type III A; NBS, newborn screening; DBS, dried blood
An improved method for glycosaminoglycan analysis by LC–MS/MS of urine samples collected on filter paper
Keywords: GAGs، glycosaminoglycans; BMT, Bone marrow transplant; CHUS, Centre hospitalier universitaire de Sherbrooke; DS, Dermatan sulfate; ERT, Enzyme replacement therapy; ESI+, Electrospray ionization in positive ion mode; GAGs, Glycosaminoglycans; Gb3, Globotriaosylceramide; HS, Heparan
Oxidative stress in patients with mucopolysaccharidosis type II before and during enzyme replacement therapy
Keywords: GAGs، glycosaminoglycans; CAT, catalase; ERT, enzyme replacement therapy; GAGs, glycosaminoglycans; LSD, lysosomal storage diseases; MDA, malondialdehyde; MPS, mucopolysaccharidoses; SOD, superoxide dismutase; TAS, total antioxidant statusMucopolysaccharidosis type II; Lysosomal s
Dermatan sulfate: Recent structural and activity data
Keywords: GAGs، glycosaminoglycans; APC, activated protein C; BDNF, brain-derived growth factor; CS, chondroitin sulfate; DS, dermatan sulfate; FGF, fibroblast growth factor; GAGs, glycosaminoglycans; GDNF, glial-derived growth factor; GlcA, glucuronic acid; GalNAc, N-acetylgalactosamine; H
Molecular size hyaluronan differently modulates toll-like receptor-4 in LPS-induced inflammation in mouse chondrocytes
Keywords: GAGs، glycosaminoglycans; Hyaluronan; Lipopolysaccharides; Cytokines; Chondrocytes; NF-kB factorDMEM, Dulbecco's modified Eagle's medium; ECM, extracellular matrix; EDTA, ethylenediaminetetraacetic acid; FBS, foetal bovine serum; GAGs, glycosaminoglycans; HA, hyaluronan; HMWHA, hi
Stability of urinary glycosaminoglycans in patients with mucopolysaccharidoses
Keywords: GAGs، glycosaminoglycans; GAGs, Glycosaminoglycans; MPS, Mucopolysaccharidoses; DMB, Dimethylmethylene blue; Stability
Changes in synovial fluid and serum biomarkers with exercise and early osteoarthritis in horses
Keywords: GAGs، glycosaminoglycans; Horse; Synovial fluid; Serum; Biomarkers; Exercise; OsteoarthritisEDTA, Ethylenediaminetetraacetic acid; ELISA, Enzyme linked immunosorbant assay; GAGs, Glycosaminoglycans
Chondroitin sulfate and heparan sulfate-containing proteoglycans are both partners and targets of basic fibroblast growth factor-mediated proliferation in human metastatic melanoma cell lines
Keywords: GAGs، glycosaminoglycans; FGF-2, basic fibroblast growth factor; CS, chondroitin sulfate; DS, dermatan sulfate; HS, heparan sulfate; GAGs, glycosaminoglycans; PGs, proteoglycansFGF-2; Heparan sulfate; Chondroitin sulfate; Human melanoma cell lines
Phosphatidylserine-positive erythrocytes bind to immobilized and soluble thrombospondin-1 via its heparin-binding domain
Keywords: GAGs، glycosaminoglycans; BCAM/LU, basal cell adhesion molecule/Lutheran protein; CSA, chondroitin sulfate A; FITC, fluorescein isothiocyanate; GAGs, glycosaminoglycans; HbSS, sickle cell anemia; HDS, high molecular weight dextran sulfate; IAP, integrin-associated protein; IgG, im
DACS, novel matrix structure composed of chondroitin sulfate proteoglycan in the brain
Keywords: GAGs، glycosaminoglycans; CS, chondroitin sulfate; CSPGs, chondroitin sulfate proteoglycans; DACS, dandelion clock-like structure; DAPI, 4′,6-diamino-2-phenyl-indole dihydro-chloride; ECM, extracellular matrix; GABA, gamma-amino-butylic acid; GAGs, glycosaminoglycans; GFAP, glial
Biophysical investigation of recombinant K5 lyase: Structural implications of substrate binding and processing
Keywords: GAGs، glycosaminoglycans; CD, circular dichroism; dp, degree of polymerisation; GAGs, glycosaminoglycans; GlcA, glucuronic acid; GlcNAc, N-acetyl-glucosamin; HS, heparan sulfate; HA, hyaluronic acid; CS, chondroitin sulfate; Kd, dissociation constant; PBS, phosphate buffered salin
Heparin enhances the furin cleavage of HIV-1 gp160 peptides
Keywords: GAGs، glycosaminoglycans; HIV-1, human immunodeficiency virus type 1; GAGs, glycosaminoglycans; CD, circular dichroism; AIDS, acquired immunodeficiency syndrome; RP-HPLC, reverse phase high performance liquid chromatography; PC, proprotein convertase; BTMD, before trans membrane d
Effect of oversulfated dermatan sulfate derivatives on platelet aggregation
Keywords: GAGs، glycosaminoglycans; DS, dermatan sulfate; GAGs, glycosaminoglycans; AT, antithrombin; HCII, heparin cofactor II, GlcA, glucuronic acid; IdoA, iduronic acid; GalNAc, N-acetyl-galactosamine.Dermatan sulfate; Platelets; Aggregation; Heparin cofactor II; Antithrombin; Coagulatio
Sulfated polymannuroguluronate, a novel anti-AIDS drug candidate, inhibits HIV-1 Tat-induced angiogenesis in Kaposi's sarcoma cells
Keywords: GAGs، glycosaminoglycans; AIDS, acquired immune deficiency syndrome; AIDS-KS, AIDS-associated Kaposi's sarcoma; bFGF, basic fibroblast growth factor; ECM, extracellular matrix; ERK, extracellular-signal regulated kinase; FAK, focal adhesion kinase; GAGs, glycosaminoglycans; GST-Ta
Chondroitin sulfate in normal human plasma is modified depending on the age. Its evaluation in patients with pseudoxanthoma elasticum
Keywords: GAGs، glycosaminoglycans; CS, chondroitin sulfate; FACE, fluorophore-assisted carbohydrate electrophoresis; GAGs, glycosaminoglycans; PXE, pseudoxanthoma elasticumGlycosaminoglycans; Chondroitin sulfate; Pseudoxanthoma elasticum; FACE; Human plasma; Blood
Decorin from different bovine tissues: Study of glycosaminoglycan chain by PAGEFS
Keywords: GAGs، glycosaminoglycans; ABCase, chondroitinase ABC; AMAC, 2-aminoacridone; GAGs, glycosaminoglycans; PAGEFS, polyacrylamide gel electrophoresis of fluorophore labelled saccharides; HPLC, high-performance liquid chromatography; UA, uronic acid; Δdi-nonSCS, 2-acetamido-2-deoxy-3-O
Mixtures of glucosamine and chondroitin sulfate reverse fibronectin fragment mediated damage to cartilage more effectively than either agent alone
Keywords: GAGs، glycosaminoglycans; Glucosamine; Chondroitin sulfate; Fibronectin fragment; Cartilage repair; Cartilage damage; Matrix metalloproteinases; ProteoglycanGluNH2, glucosamine; CS, chondroitin sulfate; GAGs, glycosaminoglycans; OA, osteoarthritis; NSAIDs, nonsteroidal anti-inflam
Respiratory syncytial virus disease mechanisms implicated by human, animal model, and in vitro data facilitate vaccine strategies and new therapeutics
Keywords: GAGs، glycosaminoglycans; Ab, antibody; AR, airway reactivity; BALF, bronchoalveolar lavage fluid; BRSV, bovine respiratory syncytial virus; COX, cyclooxygenase; cp, cold passage; CTLs, cytotoxic T lymphocytes; DCs, dendritic cells; ET, Eustachian tube; GAGs, glycosaminoglycans; H