Keywords: Alzheimer's disease; Diabetes; Insulin resistance; Inflammation; Gangliosides; mTOR; PTP1B; AβOs; Aβ peptide oligomers; AD; Alzheimer's disease; APP; amyloid precursor protein; AICD; amyloid precursor protein intracellular domain; BDNF; brain-derived ne
مقالات ISI (ترجمه نشده)
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Keywords: Inflammatory pain; Sialidase; Gangliosides;
Keywords: Alzheimer's disease; Ceramides; Cellular model; Gangliosides; Sphingolipids;
Assessment of ganglioside age-related and topographic specificity in human brain by Orbitrap mass spectrometry
Keywords: Gangliosides; Human brain; High resolution mass spectrometry; Age-and topographic specificity; Mapping; Sequencing;
Keywords: AFM; atomic force microscopy; ANS; 1-anilino-8-naphthalene sulfonate; BLES; bovine lung extract surfactant; BAM; Brewster angle microscopy; BSA; bovine serum albumin; CLSE; calf lung surfactant extract; CMC; critical micellar concentration; DM-; dimyristo
Keywords: Leukocytes; Inflammation; Maturation; Peptides; Gangliosides; Immunoglobulins; Long-chain polyunsaturated fatty acids;
Keywords: Ion mobility separation mass spectrometry (IMS MS); Gangliosides; Human fetal hippocampus; Collision-induced dissociation; Cholinergic activity;
Keywords: Alzheimer's disease; Amyloid-beta peptide; APP processing; Ceramides; Gangliosides; Sphingolipids;
Keywords: Lung cancer; Metabolomics; Biomarkers; Sputum; Polyamines; Gangliosides
Keywords: Oxidative stress; Cognitive impairments; Hesperidin; Streptozotocin; Gangliosides; Phospholipids
Keywords: Antibodies; Gangliosides; Neuropathy; Sulfatides
Keywords: Phospholipids; Hydroxyapatite chromatography; Egg yolk; Buttermilk; Gangliosides; Lipidomics
Keywords: ABPs; Antibacterial peptides; BnGalNac; benzyl-2-acetamido-2-deoxy-a-d-galactopyranoside; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; FITC; fluorescein isothiocyanate; FITC-SNA; FITC labeled Sa
Aberrant Expression of Gangliosides in Human Renal Cell Carcinomas
Keywords: kidney; glycolipids; gangliosides; carcinoma, renal cell;
Sphingolipid signaling in renal fibrosis
Keywords: Fibrosis; Kidney; Sphingolipids; Ceramide; Sphingosine 1-phosphate; Gangliosides;
Physiologically-relevant levels of sphingomyelin, but not GM1, induces a β-sheet-rich structure in the amyloid-β(1-42) monomer
Keywords: Peptide-membrane interactions; Sphingomyelin; Lipid rafts; Amyloid-β peptide; Molecular dynamics; Membrane simulations; GM1; Gangliosides; Peptide-ganglioside interactions;
Membrane-lipid homeostasis in a prodromal rat model of Alzheimer's disease: Characteristic profiles in ganglioside distributions during aging detected using MALDI imaging mass spectrometry
Keywords: AD; Alzheimer's Disease; Aβ; Beta-amyloid; GSL; Glycosphingolipids; IMS; Imaging Mass Spectrometry; MALDI; Matrix-Assisted Laser Desorption Ionization; Tg; Transgenic; Wt; Wild type; Gangliosides; MALDI imaging mass spectrometry; Aging brain; Transgenic
Membrane restructuring following in situ sialidase digestion of gangliosides: Complex model bilayers by synchrotron radiation reflectivity
Keywords: Gangliosides; NEU2; X-ray reflectometry; Single model membrane; Biomembrane; GEMs;
Aberrant ganglioside composition in glioblastoma multiforme and peritumoral tissue: A mass spectrometry characterization
Keywords: Gangliosides; Glioblastoma; Peritumoral tissue; Biomarkers; Mass spectrometry; C; chloroform; CID; collision-induced dissociation; CNS; central nervous system; GG; ganglioside; GG-SA; ganglioside-bound sialic acid; GSL; glycosphingolipid; HPTLC; high-perf
Sialidase NEU3 defines invasive potential of human glioblastoma cells by regulating calpain-mediated proteolysis of focal adhesion proteins
Keywords: FAK; Focal adhesion kinase; FA; Focal adhesion; ECM; Extracellular matrix; Suc-LLVY-AMC; Succinyl-L-leucyl-L-leucyl-L-valyl-L-tyrosine 4-methylcoumaryl-7-amide; PIP2; Phosphatidylinositol 4, 5-bisphosphate; TLC; Thin-layer chromatography; Sulfo-NHS-biotin
Water response to ganglioside GM1 surface remodelling
Keywords: Gangliosides; Sugar/water interactions; Water structuring; Raman Scattering; Depolarized Rayleigh Scattering; OH-exchange rate; NMR; Quasielastic Neutron Scattering;
Gangliosides and hearing
Keywords: Gangliosides; GM3 synthase; Auditory system; Deafness; Hair cells; Stereocilia;
Quantification of monosialogangliosides in human plasma through chemical derivatization for signal enhancement in LC–ESI-MS
Keywords: Gangliosides; Mass spectrometry; Derivatization; Signal enhancement; GM3 synthase deficiency; Neurological disorders
Diets with different lipid contents do not modify the neuronal membrane lipid raft profile in a scrapie murine model
Keywords: Prion disease; Murine model; Lipid rafts; Phospholipids; Gangliosides; Hyperlipidic diet; Hypolipidic diet
Mass spectrometry of gangliosides in extracranial tumors: Application to adrenal neuroblastoma
Keywords: Extracranial tumors; Gangliosides; Neuroblastoma; Chip-nanoelectrospray; High-resolution mass spectrometry; Fragmentation analysis; MS; mass spectrometry; nanoESI; nanoelectrospray ionization; MS/MS; tandem MS; QTOF; quadrupole time-of-flight; CID; coll
On multivalent receptor activity of GM1 in cholesterol containing membranes
Keywords: Gangliosides; Cholera toxin; Fluorescence correlation spectroscopy; Energy transfer; Antibunching;
Distinct selectivity of gangliosides required for CD4+ T and CD8+ T cell activation
Keywords: ST3Gal5; GM3 synthase; B4Galnt1; GM2/GD2 synthase; GSLs; glycosphingolipids; SA; sialic acid; CTx-B; cholera toxin B subunit; Gangliosides; Lipid rafts; T cell activation; Asthma;
Ischemic conditions and β-secretase activation: The impact of membrane cholesterol enrichment as triggering factor in rat brain endothelial cells
Keywords: CNS; central nervous system; AD; Alzheimer's disease; RBE4; rat brain endothelial cell line; OGD; oxygen and glucose deprivation; ogR; oxygen and glucose Restoration; BACE1; amyloid precursor protein (APP) β-secretase; PSEN1; presenilin-1; Aβ; amyloid p
Gangliosides: glycosphingolipids essential for normal neural development and function
Keywords: dementia; gangliosides; lipid rafts; neural development; signal transduction
Inhibition of GSK3β by pharmacological modulation of sphingolipid metabolism occurs independently of ganglioside disturbance in a cellular model of Alzheimer's disease
Keywords: Alzheimer's disease; Ceramides; Gangliosides; Glycogen synthase kinase 3; Sphingolipids;
Profiling gangliosides from milk products and other biological membranes using LC/MS
Keywords: GM; mono-sialylated gangliosides; GD; di-sialylated gangliosides; GT; tri-sialylated gangliosides; MFGM; milk fat globule membrane; TLC; thin layer chromatography; HPTLC; high performance thin layer chromatography; T-LBSA; total lipid bound sialic acid; M
Cell clustering and delay/arrest in T-cell division implicate a novel mechanism of immune modulation by E. coli heat-labile enterotoxin B-subunits
Keywords: BCR; B cell receptor; DIGs; detergent-insoluble glycolipid-enriched membranes; μ; human IgM; OVA; ovalbumin; TLR; Toll-like receptor; B cells; T cells; GM1; TLR-2; GD1; Gangliosides; Enterotoxins; Adjuvant; Vaccine;
Altered levels of α-synuclein and sphingolipids in Batten disease lymphoblast cells
Keywords: JNCL, juvenile neuronal ceroid lipofuscinosis; AD, Alzheimer's disease; PD, Parkinson's disease; GD, Gaucher's diseaseBatten disease; α-Synuclein; Sphingomyelin; Gangliosides; Autophagy; Apoptosis
Rapid and sensitive LC-ESI-MS of gangliosides
Keywords: Glycolipids; Gangliosides; LC-ESI-MS; Hydrophilic interaction chromatography
Depletion of gangliosides enhances cartilage degradation in mice
Keywords: Osteoarthritis; Mice; Gangliosides; Glycosphingolipids; Interleukin-1α;
Sphingolipid metabolism regulates development and lifespan in Caenorhabditis elegans
Keywords: Longevity; Oxidative stress; Ceramide; Gangliosides; Sphingomyelin
Sialosignaling: Sialyltransferases as engines of self-fueling loops in cancer progression
Keywords: ALL; acute lymphocytic leukemia; AML; acute myeloblastic leukemia; 5-AZA; 5â²-azacytidine; BCG; Bacillus Calmette-Guerin; CIN; chromosome instability; DP; degree of polymerization; ECM; extracellular matrix; EGF; epidermal growth factor; EGFR; epiderma
A new liquid chromatography/tandem mass spectrometry method for quantification of gangliosides in human plasma
Keywords: Gangliosides; Mass spectrometry; GM3 synthase deficiency; Neurological disorders;
Gangliosides and sialic acid effects upon newborn pathogenic bacteria adhesion: An in vitro study
Keywords: Caco-2; Gangliosides; Pathogenic bacterial adhesion; Sialic acid;
Type II heat-labile enterotoxins: Structure, function, and immunomodulatory properties
Keywords: Enterotoxins; Gangliosides; Toll-like receptors; Vaccines; Adjuvants
Very Small Size Proteoliposomes (VSSP) and Montanide combination enhance the humoral immuno response in a GnRH based vaccine directed to prostate cancer
Keywords: Cancer vaccines; GnRH; VSSP; Gonadotrophin; Gangliosides; Proteoliposomes;
Association of complex lipids containing gangliosides with cognitive development of 6-month-old infants
Keywords: Gangliosides; Complex lipids; Cognitive; Human milk; Infant formula; Infant
Altered ganglioside GD3 in HeLa cells might influence the cytotoxic abilities of NK cells
Keywords: cervical cancer; cytotoxicity; gangliosides; natural killer cells; sialidases
Serotype-specific differences in inhibition of reovirus infectivity by human-milk glycans are determined by viral attachment protein Ï1
Keywords: Reovirus; Human milk components; Gangliosides; Glucocerebroside; Sialyllactose;
Self-assembled micelles of monosialogangliosides as nanodelivery vehicles for taxanes
Keywords: Gangliosides; Paclitaxel; Docetaxel; Micelles; Drug-delivery;
Role of the 9-O-acetyl GD3 in subventricular zone neuroblast migration
Keywords: Subventricular zone; Neuroblasts; Chain migration; Gangliosides; RMS;
Expression of GD3 synthase modifies ganglioside profile and increases migration of MCF-7 breast cancer cells
Keywords: Gangliosides; GD3 synthase; Breast cancer; C-Met; MCF-7β3Gal T4, GM1a/GD1b synthase; β4GalNAc T1, GM2/GD2 synthase; BSA, Bovine Serum Albumin; Cer, ceramide; DMEM, Dulbecco's Modified Eagle's Medium; EDTA, Ethylene Diamine Tetra-acetic Acid; EGFR, Epithel
The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis
Keywords: Sialidosis; MG 132; Celastrol; Gangliosides; Lysosomal Storage Disorder; Enzyme enhancement treatment;
Applied nutritional investigationCharacterization and chronological changes of preterm human milk gangliosides
Keywords: Gangliosides; GD3; GM3; Human milk; Mothers with preterm delivery;
Estimate of dietary ganglioside intake in a group of healthy Edmontonians based on selected foods
Keywords: Gangliosides; Glycosphingolipids; Ceramides; N-acetylneuraminic acid; Milk; Cheese; Yogurt; Ground beef; Eggs; Tuna; Dietary intake; Food analysis; Food data management; Food composition;